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Elsevier电子期刊(447)

在“Elsevier电子期刊”中，命中：447条，耗时：小于0.01 秒

在所有数据库中总计命中：447条

1.ADX71943 and ADX71441, novel positive allosteric modulators of the GABA_B receptor with distinct central/peripheral profiles, show efficacy in the monosodium iodoacetate model of chronic osteoarthritis pain in the rat

作者：Mikhail Kalinichev^a ; ^{mikhail.kalinichev@ipsen.com} ; Tansy Donovan-Rodriguez^a ; Franç ; oise Girard^a ; Hasnaá ; Haddouk^a ; Isabelle Royer-Urios^a ; Manfred Schneider^a ; Simon T. Bate^b ; Cheryl Marker^c ; James D. Pomonis^c ; Sonia Poli^a

关键词：Allosteric modulation ; GABA ; GABAB ; Chronic pain ; Osteoarthritis ; ADX71943 ; ADX71441 ; Inflammatory pain ; Neuropathic pain

刊名：European Journal of Pharmacology

出版年：2017

2.The drug candidate, ADX71441, is a novel, potent and selective positive allosteric modulator of the GABA_B receptor with a potential for treatment of anxiety, pain and spasticity

作者：Mikhail Kalinichev ; ^{mikhail.kalinichev@ipsen.com} ; Franç ; oise Girard ; Hasnaà ; Haddouk ; Mé ; lanie Rouillier ; Eric Riguet ; Isabelle Royer-Urios ; Vincent Mutel ; Robert Lü ; tjens ; Sonia Poli

关键词：Allosteric modulator ; GABA ; Anxiety ; Pain ; Body temperature ; Baclofen ; Spasticity ; Clinical candidate

刊名：Neuropharmacology

出版年：2017

3.The steroid metabolite 16(β)-OH-androstenedione generated by CYP21A2 serves as a substrate for CYP19A1

作者：J. Neunzig^a ; M. Milhim^a ; L. Schiffer^a ; Y. Khatri^a ; J. Zapp^b ; A. Sá ; nchez-Guijo^c ; M.F. Hartmann^c ; S.A. Wudy^c ; R. Bernhardt^a ; ^{ritabern@mx.uni-saarland.de}

关键词：16bOHA4 ; 16beta hydroxy-androstenedione ; DOC ; deoxycorticosterone ; A4 ; androstenedione ; E1 ; estrone ; AdR ; adrenodoxin reductase ; E2 ; estradiol ; Adx ; adrenodoxin ; ER ; estrogen receptor ; AR ; androgen receptor ; FAD ; flavin adenine dinucleotide ; CPR ; cytochrome P450 reductase ; FMN ; flavin mononucleotide ; CYP ; cytochrome P450 ; p16bOHE1 ; putative 16beta hydroxy-estrone ; DHEA ; dehydroepiandrosterone ; RSS ; 11-deoxycortisol ; DLPC ; dilauroyl phosphatidylcholin ; T ; testosterone

刊名：The Journal of Steroid Biochemistry and Molecular Biology

出版年：2017

4.NMDA receptor antagonist prevents cell death in the hippocampal dentate gyrus induced by hyponatremia accompanying adrenal insufficiency in rats

作者：Hisakazu Izumida^a ; Hiroshi Takagi^a ; Haruki Fujisawa^a ; Naoko Iwata^a ; Kohtaro Nakashima^a ; Seiji Takeuchi^a ; Shintaro Iwama^a ; Takashi Namba^b ; Yukio Komatu^c ; Kozo Kaibuchi^b ; Yutaka Oiso^a ; Hiroshi Arima^a ; Yoshihisa Sugimura^a ; ^{sugiyosi@med.nagoya-u.ac.jp" class="auth_mail" title="E-mail the corresponding author}

关键词：Hyponatremia ; Adrenal insufficiency ; NMDA receptor antagonist ; Memantine ; Cell death ; Apoptosis ; Hippocampal dentate gyrus ; Basal synaptic transmission ; Long term potentiation

刊名：Experimental Neurology

出版年：2017

5.Effective adsorption of phenolic compound from aqueous solutions on activated semi coke

作者：Xiaoming Gao ; ^{dawn1026@163.com} ; Yuan Dai ; Yu Zhang ; Feng Fu ; ^{yadxfufeng@126.com}

关键词：Adsorption ; Phenolic compound ; Modification ; Coal-based ; Activated semi coke

刊名：Journal of Physics and Chemistry of Solids

出版年：2017

6.Distance and tube zeta functions of fractals and arbitrary compact sets

作者：M.L. Lapidus^a ; ¹ ; ^{lapidus@math.ucr.edu} ; G. Radunović^b ; ² ; ^{goran.radunovic@fer.hr} ; D. Žubrinić^b ; ² ; ^{darko.zubrinic@fer.hr}

关键词：Zeta function ; Distance zeta function ; Tube zeta function ; Fractal set ; Fractal string ; Box dimension ; Complex dimensions ; Principal complex dimensions ; Minkowski content ; Minkowski measurable set ; Residue ; Dirichlet-type integral ; Transcendentally quasiperiodic set ; Fractality and complex dimensions

刊名：Advances in Mathematics

出版年：2017

7.Radiosynthesis and evaluation of 5-methyl-N-(4-[¹¹C]methylpyrimidin-2-yl)-4-(1H-pyrazol-4-yl)thiazol-2-amine ([¹¹C]ADX88178) as a novel radioligand for imaging of metabotropic glutamate receptor subtype 4 (mGluR4)

作者：Masayuki Fujinaga^a ; ^&dagger ; ; Tomoteru Yamasaki^a ; ^&dagger ; ; Nobuki Nengaki^a ; ^b ; Masanao Ogawa^a ; ^b ; Katsushi Kumata^a ; Yoko Shimoda^a ; Joji Yui^a ; Lin Xie^a ; Yiding Zhang^a ; Kazunori Kawamura^a ; Ming-Rong Zhang^a ; ^{zhang@nirs.go.jp" class="auth_mail" title="E-mail the corresponding author}

关键词：mGluR4 ; PET ; Autoradiography ; [11C]ADX88178

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

8.Genetic and structural analyses of cytochrome P450 hydroxylases in sex hormone biosynthesis: Sequential origin and subsequent coevolution

作者：Jared V. Goldstone^b ; ¹ ; Munirathinam Sundaramoorthy^a ; ¹ ; Bin Zhao^a ; Michael R. Waterman^a ; John J. Stegeman^b ; ^{jstegeman@whoi.edu" class="auth_mail" title="E-mail the corresponding author} ; David C. Lamb^c ; ^{D.C.Lamb@swansea.ac.uk" class="auth_mail" title="E-mail the corresponding author}

关键词：Adx ; adrenodoxin ; CYP ; cytochrome P450 monooxygenase ; HSD ; hydroxysteroid dehydrogenase ; PREG ; pregnenolone ; DHEP ; dehydroepiandrostenedione ; AND ; androstenedione ; PRG ; progesterone ; TEST ; testosterone ; POR ; cytochrome P450 reductase

刊名：Molecular Phylogenetics and Evolution

出版年：2016

9.Biotransformation of the mineralocorticoid receptor antagonists spironolactone and canrenone by human CYP11B1 and CYP11B2: Characterization of the products and their influence on mineralocorticoid receptor transactivation

作者：Lina Schiffer^a ; ¹ ; Anne-Rose Mü ; ller^a ; ¹ ; Anna Hobler^a ; Simone Brixius-Anderko^a ; Josef Zapp^b ; Frank Hannemann^a ; Rita Bernhardt^a ; ^{ritabern@mx.uni-saarland.de" class="auth_mail" title="E-mail the corresponding author}

关键词：AdR ; adrenodoxin reductase ; Adx ; adrenodoxin ; DOC ; 11-deoxycorticosterone ; E. coli ; Escherichia coli ; MR ; mineralocorticoid receptor ; MRA ; mineralocorticoid receptor antagonist ; NMR ; nuclear magnetic resonance ; RSS ; 11-deoxycortisol (Reichstein&rsquo ; s substance S)

刊名：Journal of Steroid Biochemistry and Molecular Biology

出版年：2016

10.Metabotropic glutamate receptors as targets for new antipsychotic drugs: Historical perspective and critical comparative assessment

作者：Joanna M. Wierońska^a ; Stevin H. Zorn^b ; Dario Doller^b ; Andrzej Pilc^a ; ^{nfpilc@cyf-kr.edu.pl" class="auth_mail" title="E-mail the corresponding author}

关键词：ACPT-I ; (1S ; 3R ; 4S)-1-Aminocyclopentane-13 ; 4-tricarboxylic acid ; ADX ; addex ; AMN082 ; N ; N&prime ; -Bis(diphenylmethyl)-1 ; 2-ethanediamine dihydrochloride ; L-AP-4 ; L-(+)-2-Amino-4-phosphonobutyric acid ; AMP ; amphetamine ; APO ; apomorphine ; BINA ; Biphenyl-indanone A ; CAR ; conditioned avoidance reaction ; CDPPB ; 3-Cyano-N-(1 ; 3-diphenyl-1H-pyrazol-5-yl)benzamide ; CFMTI ; 2-cyclopropyl-5-[1-(2-fluoropyridin-3-yl)-5-methyl-1H-12 ; 3-triazol-4-yl]-2 ; 3-dihydro-1H-isoindol-1-one ; CNS ; central nervous system ; CSF

刊名：Pharmacology and Therapeutics

出版年：2016

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