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1.Orally active epoxyeicosatrienoic acid analog does not exhibit antihypertensive and reno- or cardioprotective actions in two-kidney, one-clip Goldblatt hypertensive rats

作者：Petra Al&aacute ; nov&aacute ; ^a ; ^{Petra.Alanova@fgu.cas.cz" class="auth_mail" title="E-mail the corresponding author} ; Zuzana Huskov&aacute ; ^b ; ^{zuzka.huska@email.cz" class="auth_mail" title="E-mail the corresponding author} ; Libor Kopkan^b ; ^{likp@medicon.cz" class="auth_mail" title="E-mail the corresponding author} ; Alexandra Sporkov&aacute ; ^b ; ^{alhc@medicon.cz" class="auth_mail" title="E-mail the corresponding author} ; &Scaron ; &aacute ; rka Jí ; chov&aacute ; ^b ; ^{savr@medicon.cz" class="auth_mail" title="E-mail the corresponding author} ; Jan Neck&aacute ; 艡^a ; ^c ; ^{neckar@biomed.cas.cz" class="auth_mail" title="E-mail the corresponding author} ; John D. Imig^c ; ^{jdimig@mcw.edu" class="auth_mail" title="E-mail the corresponding author} ; Martina Klevstig^a ; ^{kolar@biomed.cas.cz" class="auth_mail" title="E-mail the corresponding author} ; Franti&scaron ; ek Kol&aacute ; 艡^a ; ^{kolar@biomed.cas.cz" class="auth_mail" title="E-mail the corresponding author} ; N. Rami Reddy^d ; ^{J.Falck@UTSouthwestern.edu" class="auth_mail" title="E-mail the corresponding author} ; John R. Falck^d ; ^{J.Falck@UTSouthwestern.edu" class="auth_mail" title="E-mail the corresponding author} ; Janusz Sadowski^e ; ^{sajan0@op.pl" class="auth_mail" title="E-mail the corresponding author} ; Akira Nishiyama^f ; ^{akira@kms.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Herbert J. Kramer^g ; ^{hkramer@uni-bonn.de" class="auth_mail" title="E-mail the corresponding author} ; Vojt臎ch Melenovský ; ^h ; ^{vome@medicon.cz" class="auth_mail" title="E-mail the corresponding author} ; Lenka 膶ervenkov&aacute ; ^b ; ^{cerl@medicon.cz" class="auth_mail" title="E-mail the corresponding author} ; Petr Kujal^b ; ⁱ ; Zdenka Vernerov&aacute ; ^b ; ⁱ ; Lud臎k 膶ervenka^b ; ^j ; ^{luce@medicon.cz" class="auth_mail" title="E-mail the corresponding author} ; ^{ludek.cervenka@ikem.cz" class="auth_mail" title="E-mail the corresponding author}

关键词：2K1C ; two-kidney ; one-clip ; ANG 1-7 ; angiotensin-(1-7) ; AT1 ; receptors for angiotensin II ; type 1 ; AT2 ; receptors for angiotensin II ; type 2 ; ANG II ; angiotensin II ; ANG III ; angiotensin III ; Akt ; protein kinase B ; AR ; area at risk ; BP ; blood pressure ; CYP ; cytochrome P-450 ; DHETEs ; dihydroxyeicosatrienoic acids ; EET-A ; 14 ; 15-epoxyeicosatrienoic acids analog ; EETs ; epoxyeicosatrienoic acids ; GSK-3ß ; glycogen synthase kinase 3ß ; HanSD rats ; Hannover Sprague-Dawley transgene-negative r

刊名：Vascular Pharmacology

出版年：2015

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