设为首页
收藏本站
网站地图
|
English
|
公务邮箱
About the library
Background
History
Leadership
Organization
Readers' Guide
Opening Hours
Collections
Help Via Email
Publications
Electronic Information Resources
常用资源
电子图书
期刊论文
学位会议
外文资源
特色专题
内部出版物
Wiley电子期刊(5)
NATURE电子期刊(1)
ACS电子期刊(22)
SpringerLink电子期刊(80)
Elsevier电子期刊(167)
在“
Elsevier电子期刊
”中,
命中:
167
条,耗时:0.0679668 秒
在所有数据库中总计命中:
275
条
1.
Drug
-to-
antibody
determination for an
antibody
-
drug
-conjugate utilizing cathepsin B digestion coupled with reversed-phase high-pressure liquid chromatography analysis
作者:
Michael
Ada
mo
a
;
michael.
ada
mo@bms.com
;
Guoyong Sun
a
;
Difei Qiu
b
;
Joseph Valente
b
;
Wenkui Lan
b
;
Hangtian Song
a
;
Mark Bolgar
b
;
Amit Katiyar
a
;
Girija Krishnamurthy
a
关键词:
Cathepsin B
;
DAR
;
Drug
to
antibody
ratio
;
ADC
;
Antibody
drug
conjugate
刊名:Journal of Chromatography A
出版年:2017
2.
Inhibition of interleukin-5 induced false positive anti-
drug
antibody
responses against mepolizumab through the use of a competitive blocking
antibody
作者:
Karen Liao
;
karen.x.liao@gsk.com
;
Erik Meyer
;
Thomas N. Lee
;
Amy Loercher
;
Daniel Sikkema
关键词:
Anti-
drug
antibodies (
ADA
)
;
Immunogenicity
;
IL-5
;
Mepolizumab
刊名:Journal of Immunological Methods
出版年:2017
3.
Withania somnifera chemotype NMITLI 101R significantly increases the efficacy of antileishmanial
drug
s by generating strong IFN-γ and IL-12 mediated immune responses in Leishmania donovani infected hamsters
作者:
Chandra Dev Pati Tripathi
a
;
Pramod Kumar Kushawaha
a
;
d
;
Rajender Singh Sangwan
b
;
Chitra Mandal
c
;
Shailja Misra-Bhattacharya
a
;
Anuradha Dube
a
;
anuradhadube@gmail.com
;
anuradha_dube@rediffmail.com
;
anuradha_dube@hotmail.com
关键词:
Withania somnifera
;
Chemotype NMITLI 101R
;
Leishmania donovani
;
Th1 response
;
Delayed type hypersensitivity (DTH)
刊名:Phytomedicine
出版年:2017
4.
Indirect assessment of neutralizing anti-
drug
antibodies utilizing pharmacokinetic assay data
作者:
Christian Vettermann
1
;
Jessica Ortiz
;
Stephanie Lee
;
Sergio Sanchez
;
Hannah P. Victor
;
Mark Ma
;
Timothy Heath
;
Shalini Gupta
;
shalinig@amgen.com" class="auth_mail" title="E-mail the corresponding author
关键词:
ADA
;
anti-
drug
antibody
;
ACP
;
assay cutpoint
;
CDM
;
compact disc microstructures
;
CDR
;
complementary determining region
;
Fc
;
Fragment crystallizable
;
F/T
;
ratio of free to total
drug
concentrations
;
iNAb
;
indirect NAb assessment
;
LLRD
;
lower limit of reliable detection
;
LLOQ
;
lower limit of quantification
;
NAb
;
neutralizing anti-
drug
antibody
;
PCS
;
pooled cynomolgus monkey serum
;
QC
;
quality control
;
PK
;
pharmacokinetic
;
RLU
;
relative luminescence unit
;
SEM
;
standard error of the mean
;
STD
;
stand
刊名:Journal of Immunological Methods
出版年:2016
5.
Practical method development for the separation of monoclonal antibodies and
antibody
-
drug
-conjugate species in hydrophobic interaction chromatoraphy, part 2: Optimization of the phase system
作者:
Alessandra Cusumano
a
;
Davy Guillarme
b
;
Alain Beck
c
;
1
;
Szabolcs Fekete
b
;
szabolcs.fekete@unige.ch" class="auth_mail" title="E-mail the corresponding author
关键词:
Hydrophobic interaction chromatography
;
Monoclonal
antibody
;
Antibody
-
drug
-conjugate
;
Method development
;
Brentuximab-vedotin
刊名:Journal of Pharmaceutical and Biomedical Analysis
出版年:2016
6.
Affinity capture elution bridging assay: A novel immunoassay format for detection of anti-therapeutic protein antibodies
作者:
Yan Q. Chen
;
Thomas G. Pottanat
;
Quincy L. Carter
;
Jason S. Troutt
;
Robert J. Konrad
;
John H. Sloan
关键词:
MSD
;
MesoScale Discovery
;
ECL
;
electrochemiluminescence
;
ACE
;
affinity capture elution
;
ADA
;
anti-
drug
antibody
;
TAb
;
therapeutic
antibody
;
MRD
;
minimum require dilution
;
TMB
;
3
;
3&prime
5 ;
5&prime
;
tetramethylbenzidine
;
HRP
;
horseradish peroxidase
;
NHS
;
normal human serum
;
TBS
;
Tris-buffered saline
;
SEM
;
standard error of the mean
刊名:Journal of Immunological Methods
出版年:2016
7.
Advancing pharmaceutical quality: An overview of science and research in the U.S. FDA’s Office of Pharmaceutical Quality
作者:
Ada
m C. Fisher
a
;
Sau L. Lee
a
;
sau.lee@fda.hhs.gov
;
Daniel P. Harris
a
;
Lucinda Buhse
a
;
Steven Kozlowski
a
;
Lawrence Yu
a
;
Michael Kopcha
a
;
Janet Woodcock
b
关键词:
ADF
;
abuse deterrent formulation
;
API
;
active pharmaceutical ingredient
;
T-DM1
;
Ado-Trastuzumab Emtansine
;
ADC
;
antibody
-
drug
conjugate
;
CDER
;
center for
drug
evaluation and research
;
CBRN/EID
;
chemical
;
biological
;
radiological/nuclear and emerging infectious disease
;
CMC
;
chemistry
;
manufacturing
;
and controls
;
DMD
;
Duchenne muscular dystrophy
;
DLS
;
dynamic light scattering
;
FDA
;
food and
drug
administration
;
FTIR
;
Fourier transform infrared spectroscopy
;
GA
;
glatiramer acetate
;
IVIVC
;
in vivo
刊名:International Journal of Pharmaceutics
出版年:2016
8.
Design of a Bayesian
ada
ptive phase 2 proof-of-concept trial for BAN2401, a putative disease-modifying monoclonal
antibody
for the treatment of Alzheimer's disease
作者:
Andrew Satlin
a
;
Andrew_Satlin@eisai.com" class="auth_mail" title="E-mail the corresponding author
;
Jinping Wang
a
;
Veronika Logovinsky
a
;
Scott Berry
b
;
Chad Swanson
a
;
Shobha Dhadda
a
;
Donald A. Berry
b
关键词:
Bayesian analysis
;
Ada
ptive trial
;
Alzheimer's disease
;
Interim analysis
;
Monoclonal
antibody
;
Clinical trial simulation
刊名:Alzheimer's & Dementia: Translational Research & Clinical Interventions
出版年:2016
9.
Immune response to enzyme replacement therapies in lysosomal storage diseases and the role of immune tolerance induction
作者:
Priya S. Kishnani
a
;
priya.kishnani@duke.edu" class="auth_mail" title="E-mail the corresponding author
;
Patricia I. Dickson
b
;
pdickson@labiomed.org" class="auth_mail" title="E-mail the corresponding author
;
Laurie Muldowney
c
;
laurie.muldowney@fda.hhs.gov" class="auth_mail" title="E-mail the corresponding author
;
Jessica J. Lee
c
;
jessica.j.lee@fda.hhs.gov" class="auth_mail" title="E-mail the corresponding author
;
Amy Rosenberg
d
;
amy.rosenberg@fda.hhs.gov" class="auth_mail" title="E-mail the corresponding author
;
Rekha Abichandani
e
;
rabichan@shire.com" class="auth_mail" title="E-mail the corresponding author
;
Jeffrey A. Bluestone
f
;
jeff.bluestone@ucsf.edu" class="auth_mail" title="E-mail the corresponding author
;
Barbara K. Burton
g
;
bburton@luriechildrens.org" class="auth_mail" title="E-mail the corresponding author
;
Maureen Dewey
c
;
maureen.dewey@fda.hhs.gov" class="auth_mail" title="E-mail the corresponding author
;
Alexandra Freitas
h
;
afreitas@rarediseases.org" class="auth_mail" title="E-mail the corresponding author
;
Derek Gavin
h
;
dgavin@rarediseases.org" class="auth_mail" title="E-mail the corresponding author
;
Donna Griebel
c
;
donna.griebel@fda.hhs.gov" class="auth_mail" title="E-mail the corresponding author
;
Melissa Hogan
i
;
melissa@savingcase.com" class="auth_mail" title="E-mail the corresponding author
;
Stephen Holland
j
;
steve.holland@thomsonreuters.com" class="auth_mail" title="E-mail the corresponding author
;
Pranoot Tanpaiboon
k
;
ptanpaib@childrensnational.org" class="auth_mail" title="E-mail the corresponding author
;
Laurence A. Turka
l
;
lturka@partners.org" class="auth_mail" title="E-mail the corresponding author
;
Jeanine J. Utz
m
;
utz002@umn.edu" class="auth_mail" title="E-mail the corresponding author
;
Yow-Ming Wang
n
;
yowming.wang@fda.hhs.gov" class="auth_mail" title="E-mail the corresponding author
;
Chester B. Whitley
m
;
whitley@umn.edu" class="auth_mail" title="E-mail the corresponding author
;
Zoheb B. Kazi
a
;
zoheb.kazi@dm.duke.edu" class="auth_mail" title="E-mail the corresponding author
;
Anne R. Pariser
o
;
anne.pariser@fda.hhs.gov" class="auth_mail" title="E-mail the corresponding author
关键词:
Ab
;
antibody
;
ADA
s
;
anti-
drug
antibodies
;
Ag
;
antigen
;
BiPAP
;
bilevel positive airway pressure
;
CDER
;
Center for
Drug
Evaluation and Research
;
CNS
;
central nervous system
;
CRIM
;
cross-reactive immunologic material
;
DGIEP
;
Division of Gastroenterology and Inborn Errors of Metabolism
;
ERT
;
enzyme replacement therapy
;
FcR
;
Fc receptor
;
FDA
;
Food and
Drug
Administration
;
GAA
;
acid alpha glucosidase
;
GAG
;
glycosaminoglycans
;
HLA
;
human leukocyte antigen
;
HSAT
;
high and sustained anti-rhGAA IgG antibo
刊名:Molecular Genetics and Metabolism
出版年:2016
10.
Immunogenicity screening assay development for a novel human-mouse chimeric anti-CD147 monoclonal
antibody
(Metuzumab)
作者:
Li Mi
a
;
1
;
Wei Li
b
;
1
;
Maohua Li
c
;
Tao Chen
a
;
Muyang Wang
c
;
Le Sun
c
;
sunl@
antibody
china.com" class="auth_mail" title="E-mail the corresponding author
;
Zhinan Chen
d
;
znchen@fmmu.edu.cn" class="auth_mail" title="E-mail the corresponding author
关键词:
Anti-CD147 mAb (Metuzumab)
;
Anti-
drug
antibody
(
ADA
)
;
Immunogenicity
;
Bridging ELISA assay
刊名:Journal of Immunological Methods
出版年:2016
1
2
3
4
5
6
7
8
9
按检索点细分(167)
关键词(27)
文摘(95)
按出版年细分(167)
2027年及以后(9)
2017年(3)
2016年(17)
2015年(6)
2013年(26)
2012年(15)
2011年(16)
2010年(17)
2009年(8)
2008年(12)
2007年(8)
2006年(3)
2005年(2)
2004年(2)
2003年(2)
2002年(1)
2001年(1)
2000年(4)
2000年及以前(15)
NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via
email
.