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Wiley电子期刊(1)
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Elsevier电子期刊(136)
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NATURE电子期刊(4)
ACS电子期刊(47)
在“
Elsevier电子期刊
”中,
命中:
136
条,耗时:0.015993 秒
在所有数据库中总计命中:
240
条
1.
Synthesis, structure-activity relationships and biological evaluation of 7-phenyl-pyrroloquinolinone 3-amide derivatives as potent
antimitotic
agents
作者:
Davide Carta
a
;
Roberta Bortolozzi
b
;
Mattia Sturlese
a
;
Veronica Salmaso
a
;
Ernest Hamel
c
;
Giuseppe Basso
b
;
Laura Calderan
a
;
Luigi Quintieri
a
;
Stefano Moro
a
;
Giampietro Viola
b
;
Maria Grazia Ferlin
a
;
mariagrazia.ferlin@unipd.it
关键词:
Microtubules
;
Phenylpyrroloquinolinone
;
Tubulin
;
Apoptosis
;
Molecular docking
;
Structure-activity relationships
刊名:European Journal of Medicinal Chemistry
出版年:2017
2.
Design, synthesis of phenstatin/isocombretastatin-oxindole conjugates as
antimitotic
agents
作者:
G. Bharath Kumar
a
;
V. Lakshma Nayak
a
;
Ibrahim Bin Sayeed
a
;
Vangala Santhosh Reddy
a
;
Anver Basha Shaik
a
;
Rasala Mahesh
a
;
Mirza Feroz Baig
a
;
Mohd Adil Shareef
a
;
A. Ravikumar
b
;
Ahmed Kamal
a
;
b
;
c
;
ahmedkamal@iict.res.in" class="auth_mail" title="E-mail the corresponding author
关键词:
Phenstatin/isocombretastatin-oxindole
;
Tubulin depolymerization
;
Annexin V-FITC and mitochondrial membrane depolarization
刊名:Bioorganic & Medicinal Chemistry
出版年:2016
3.
Design and synthesis of cis-restricted benzimidazole and benzothiazole mimics of combretastatin A-4 as
antimitotic
agents
with apoptosis inducing ability
作者:
Md. Ashraf
a
;
Thokhir B. Shaik
a
;
c
;
M. Shaheer Malik
a
;
Riyaz Syed
a
;
Prema L. Mallipeddi
b
;
M.V.P.S. Vishnu Vardhan
a
;
Ahmed Kamal
a
;
ahmedkamal@iict.res.in" class="auth_mail" title="E-mail the corresponding author
关键词:
Tubulin inhibitor
;
Combretastatin A-4
;
Benzimidazole
;
Benzothiazole
;
Apoptosis
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2016
4.
Vascular disrupting activity of combretastatin analogues
作者:
Elena Porcù
;
a
;
1
;
Alessia Salvador
b
;
1
;
Irina Primac
b
;
Stefania Mitola
c
;
Roberto Ronca
c
;
Cosetta Ravelli
c
;
Roberta Bortolozzi
a
;
Daniela Vedaldi
b
;
Romeo Romagnoli
d
;
Giuseppe Basso
a
;
Giampietro Viola
a
;
giampietro.viola.1@unipd.it" class="auth_mail" title="E-mail the corresponding author
关键词:
Vascular disrupting
agents
;
Angiogenesis
;
Combretastatin
;
Tubulin binding
agents
;
HUVEC
刊名:Vascular Pharmacology
出版年:2016
5.
CWF-145, a novel synthetic quinolone derivative exerts potent
antimitotic
activity against human prostate cancer: Rapamycin enhances
antimitotic
drug-induced apoptosis through the inhibition of Akt/mTOR pathway
作者:
Chao-Ming Hung
a
;
b
;
Ying-Chao Lin
c
;
d
;
e
;
Liang-Chih Liu
f
;
g
;
Sheng-Chu Kuo
h
;
Chi-Tang Ho
i
;
Tzong-Der Way
j
;
k
;
tdway@mail.cmu.edu.tw" class="auth_mail" title="E-mail the corresponding author
关键词:
CWF-145
;
Prostate cancer
;
G2/M arrest
;
Akt/mTOR
;
Rapamycin
刊名:Chemico-Biological Interactions
出版年:2016
6.
Dual effect of F-actin targeted carrier combined with
antimitotic
drug on aggressive colorectal cancer cytoskeleton: Allying dissimilar cell cytoskeleton disrupting mechanisms
作者:
Shahrouz Taranejoo
a
;
b
;
Mohsen Janmaleki
c
;
d
;
Mohammad Pachenari
c
;
d
;
Seyed Morteza Seyedpour
e
;
Ramya Chandrasekaran
a
;
Wenlong Cheng
a
;
Kerry Hourigan
b
;
kerry.hourigan@monash.edu" class="auth_mail" title="E-mail the corresponding author
关键词:
Cytoskeleton
;
Actin microfilaments
;
Microtubules
;
Cancer
;
Microtubule-targeting agent
;
Albendazole
刊名:International Journal of Pharmaceutics
出版年:2016
7.
Synthesis and biological evaluation of 6H-pyrido[2鈥?1鈥?2,3]imidazo[4,5-c]isoquinolin-5(6H)-ones as
antimitotic
agents
and inhibitors of tubulin polymerization
作者:
Tao Meng
;
Wei Wang
;
Zhixiang Zhang
;
Lanping Ma
;
Yongliang Zhang
;
Zehong Miao
;
Jingkang Shen
关键词:
6H-Pyrido[2&prime
;
1&prime
2 ;
3]imidazo[4
;
5-c]isoquinolin-5(6H)-ones
;
Antitumor
agents
;
Inhibitors of tubulin polymerization
;
Colchicine binding site
刊名:Bioorganic and Medicinal Chemistry
出版年:15 January, 2014
8.
Antimitotic
and vascular disrupting
agents
: 2-Hydroxy-3,4,5-trimethoxybenzophenones
作者:
Chih-Yi Chang
a
;
Hsun-Yueh Chuang
a
;
Hsueh-Yun Lee
a
;
Teng-Kuang Yeh
e
;
Ching-Chuan Kuo
e
;
Chi-Yen Chang
b
;
Jang-Yang Chang
b
;
d
;
jychang@nhri.org.tw" class="auth_mail
;
Jing-Ping Liou
a
;
c
;
jpl@tmu.edu.tw" class="auth_mail
关键词:
Vascular-disrupting
agents
;
Antiproliferative
;
CA-4
刊名:European Journal of Medicinal Chemistry
出版年:22 April, 2014
9.
Elaboration of thorough simplified vinca alkaloids as
antimitotic
agents
based on pharmacophore similarity
作者:
Jing Zheng
;
Lijuan Deng
;
Minfeng Chen
;
Xuzhi Xiao
;
Shengwei Xiao
;
Cuiping Guo
;
Gaokeng Xiao
;
Liangliang Bai
;
Wencai Ye
;
Dongmei Zhang
;
Heru Chen
关键词:
Pharmacophore similarity
;
Vinca alkaloid
;
Antimitotic
agent
;
Anticancer
刊名:European Journal of Medicinal Chemistry
出版年:2013
10.
SP600125 overcomes
antimitotic
drug-resistance in cancer cells by increasing apoptosis with independence of P-gp inhibition
作者:
Ju-Hwa Kim
;
Minji Chae
;
Ae-Ran Choi
;
Hyung Sik Kim
;
Sungpil Yoon
关键词:
Jnk
;
c-Jun N-terminal kinase
;
S.D.
;
Standard deviation
;
SP
;
SP600125
;
PAC
;
Paclitaxcel
;
DOC
;
Docetaxcel
;
VIB
;
Vinblastine
;
COL
;
Colchicine
;
DOX
;
Doxorubicin
;
MDR
;
Multi drug-resistance
;
P-gp
;
P-glycoprotein
;
DMSO
;
Dimethylsulfoxide
;
FACS
;
Fluorescence-activated cell sorting
;
FBS
;
Fetal bovine serum
;
TCA
;
Trichloroacetic acid
;
C-PARP
;
Cleaved poly ADP ribose polymerase
;
PBS
;
Phosphate buffered saline
;
SDS-PAGE
;
Sodium dodecyl sulfate-polyacrylamide gel electrophoresis
;
RT
;
Room temperature
刊名:European Journal of Pharmacology
出版年:15 January, 2014
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