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在“
Elsevier电子期刊
”中,
命中:
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在所有数据库中总计命中:
2,675
条
1.
Shikonin inhi
b
its gefitini
b
-resistant non-small
cell
lung cancer
b
y inhi
b
iting TrxR and
activating
the EGFR proteasomal degradation pathway
作者:
Xia Li
1
;
Xing-Xing Fan
1
;
Ze-
B
o Jiang
;
Wings TY Loo
;
Xiao-Jun Yao
;
Elaine Lai-Han Leung
;
lhleung@must.edu.mo
;
Louis WC Chow
;
wcchow@must.edu.mo
;
Liang Liu
;
lliu@must.edu.mo
关键词:
NSCLC
;
non-small
cell
lung cancer
cell
;
ROS
;
reactive oxygen species
;
EGFR
;
epidermal growth
factor
receptor
;
T790M
;
a su
b
stitution mutation of threonine with methionine at position 790 of EGFR
;
TrxR
;
thioredoxin reductases
;
MTT
;
3-(4
;
5-dimetrylthiazol)-2
;
5-diphenyltetrazolium
b
romide
;
DCFDA
;
dichlorofluorescein diacetate
;
P
B
S
;
phosphate-
b
uffered saline
;
RIPA
;
radioimmunoprecipitation assay
;
PARP
;
poly (ADP-ri
b
osyl) polymerase
;
NAC
;
N-acetyl-l-cysteine
;
MG132
;
proteasomal degradation pathway inh
刊名:Pharmacological Research
出版年:2017
2.
Treatment Rationale and Study Design for the RELAY Study: A Multicenter, Randomized, Dou
b
le-Blind Study of Erlotini
b
With Ramuciruma
b
or Place
b
o in Patients With Epidermal Growth
Factor
Receptor
Mutation-Positive Metastatic Non-Small-
Cell
Lung Cancer
作者:
Edward
B
. Garon
1
;
Martin Reck
2
;
Luis Paz-Ares
3
;
Santiago Ponce
3
;
Jesus Corral Jaime
4
;
Oscar Juan
5
;
Ernest Nadal
6
;
Pa
b
lo Lee
7
;
Rita Dalal
7
;
Jingyi Liu
8
;
Shuang He
8
;
Joseph Treat
8
;
Kazuhiko Nakagawa
9
;
nakagawa@med.kindai.ac.jp
关键词:
Epidermal growth
factor
receptor
mutation
;
Erlotini
b
;
Non-small
cell
lung cancer
;
Ramuciruma
b
;
RELAY trial
刊名:Clinical Lung Cancer
出版年:2017
3.
Phase 2 Study of Erlotini
b
in Com
b
ination With Linsitini
b
(OSI-906) or Place
b
o in Chemotherapy-Naive Patients With Non-Small-
Cell
Lung Cancer and
Activating
Epidermal Growth
Factor
Receptor
Mutations
作者:
Natasha
B
. Leighl
1
;
Naiyer A. Rizvi
2
;
Lopes Gil
b
erto de Lima Jr.
3
;
4
;
Wichit Arpornwirat
5
;
Charles M. Rudin
6
;
Al
b
erto A. Chiappori
7
;
Myung-Ju Ahn
8
;
Laura Q.M. Chow
9
;
Lyudmila
B
azhenova
10
;
Arunee Dechaphunkul
11
;
Patrapim Sunpaweravong
12
;
Keith Eaton
13
;
14
;
Jihong Chen
15
;
Sonja Medley
15
;
Srinivasu Poondru
15
;
Margaret Singh
15
;
Joyce Stein
b
erg
15
;
Rosalyn A. Juergens
16
;
juergensr@hhsc.ca
;
Shirish M. Gadgeel
17
;
18
关键词:
Com
b
ination
;
Epidermal growth
factor
receptor
inhi
b
itor
;
First-line therapy
;
Insulin-like growth
factor
-1 inhi
b
itor
;
Tyrosine kinase inhi
b
itor
刊名:Clinical Lung Cancer
出版年:2017
4.
Cord
b
lood natural killer
cell
s expressing a dominant negative TGF-β
receptor
: Implications for adoptive immunotherapy for glio
b
lastoma
作者:
Eric S. Yvon
1
;
Rachel
B
urga
2
;
Allison Powell
2
;
Conrad R. Cruz
2
;
Rohan Fernandes
2
;
Cecilia
B
arese
2
;
Tuongvan Nguyen
1
;
Mohamed S. A
b
del-Baki
3
;
Catherine M.
B
ollard
2
;
c
b
ollard@cnmc.org
关键词:
cord
b
lood natural killer
cell
s
;
dominant negative
receptor
;
glioma
;
immunotherapy
;
TGF-β
刊名:Cytotherapy
出版年:2017
5.
Role of
B
cell
s in the pathogenesis of systemic sclerosis
作者:
S. Sanges
a
;
b
;
c
;
d
;
e
;
T. Guerrier
a
;
b
;
f
;
D. Launay
a
;
b
;
c
;
d
;
e
;
david.launay@chru-lille.fr
;
G. Lefè
;
vre
a
;
b
;
c
;
d
;
e
;
f
;
M. La
b
alette
a
;
b
;
e
;
f
;
A. Forestier
a
;
b
;
c
;
d
;
e
;
V. So
b
anski
a
;
b
;
c
;
d
;
e
;
J. Corli
a
;
b
;
e
;
g
;
C. Hauspie
a
;
b
;
f
;
M. Jendou
b
i
a
;
b
;
I. Yakou
b
-Agha
a
;
b
;
e
;
h
;
P.-Y. Hatron
a
;
c
;
d
;
e
;
E. Hachulla
a
;
b
;
c
;
d
;
e
;
S. Du
b
ucquoi
a
;
b
;
e
;
f
关键词:
Systemic sclerosis
;
B
cell
;
CD19
;
B
AFF
;
Rituxima
b
刊名:La Revue de Médecine Interne
出版年:2017
6.
Tricking the
b
alance: NK
cell
s in anti-cancer immunity
作者:
Jens Pahl
;
j.pahl@dkfz.de" class="auth_mail" title="E-mail the corresponding author
;
Adelheid Cerwenka
a.cerwenka@dkfz.de" class="auth_mail" title="E-mail the corresponding author
关键词:
NK
cell
;
Innate immunity
;
Cancer
;
Immunotherapy
刊名:Immuno
b
iology
出版年:2017
7.
The
b
inding of the
b
one morphogenetic protein antagonist gremlin to kidney heparan sulfate: Such
b
inding is not essential for BMP antagonism
作者:
Arnold Junior Tatsinkam
a
;
1
;
Naomi Rune
a
;
Joy Smith
a
;
2
;
Jill T. Norman
b
;
B
ar
b
ara Mulloy
a
;
Christopher C. Rider
a
;
c.rider@rhul.ac.uk
关键词:
B
MP
;
b
one morphogenetic protein
;
CAN
;
Cer
b
erus and DAN
;
CKD
;
chronic kidney disease
;
DAN
;
differentially screening selected gene a
bb
erative in neuro
b
lastoma
;
FGF
;
fi
b
ro
b
last growth
factor
;
GAG
;
glycosaminoglycan
;
HS
;
heparan sulfate
;
MGR
;
mutant gremlin
;
TGFβ
;
transforming growth
factor
b
eta
;
VEGF
;
vascular endothelial growth
factor
;
VEGFR2
;
VEGF
receptor
2
刊名:The International Journal of
B
iochemistry &
Cell
Biology
出版年:2017
8.
Intra
cell
ular signaling modifications involved in the anti-inflammatory effect of 4-alkoxy-6,9-dichloro[1,2,4]triazolo[4,3-a]quinoxalines on macrophages
作者:
Antonio J. Ruiz-Alcaraz
a
;
ajruiz@um.es
;
Marí
;
a Tristá
;
n-Manzano
a
;
Antonio Guirado
b
;
Jesú
;
s Gá
;
lvez
c
;
Marí
;
a Martí
;
nez-Esparza
a
;
Pilar Garcí
;
a-Peñ
;
arru
b
ia
a
;
pigarcia@um.es
关键词:
ATF
;
activating
transcription
factor
;
CCM
;
complete culture medium
;
ERK
;
extra
cell
ular signal-regulated kinase
;
IKK
;
Iκ
B
kinase
;
IL-6
;
interleukin 6
;
JNK
;
c-Jun N-terminal kinase
;
LPS
;
lipopolysaccharide
;
MAPK
;
mitogen-activated protein kinase
;
NSAIDs
;
non-steroidal anti-inflammatory drugs
;
NFκ
B
;
nuclear
factor
kappa-light-chain-enhancer of activated
B
cell
s
;
PAMP
;
pathogen-associated molecular patterns
;
PI3K
;
phosphatidylinositol 3-kinase
;
PK
B
;
protein kinase
B
;
PRRs
;
PAMP recognition
receptor
s
刊名:European Journal of Pharmaceutical Sciences
出版年:2017
9.
Randomized Phase 2 Trial of Pharmacodynamic Separation of Pemetrexed and Intercalated Erlotini
b
Versus Pemetrexed Alone for Advanced Nonsquamous, Non-small-
cell
Lung Cancer
作者:
Tianhong Li
1
;
6
;
thli@ucdavis.edu
;
B
ilal Piperdi
2
;
William V. Walsh
3
;
Mimi Kim
4
;
Laurel A.
B
eckett
1
;
5
;
Rasim Gucalp
2
;
Missak Haigentz Jr.
2
;
Venu G.
B
athini
3
;
Huiyu Wen
1
;
Kaili Zhou
1
;
Patricia
B
. Pasquinelli
1
;
Srikanth Gajavelli
2
;
Meera Sreedhara
3
;
Xianhong Xie
4
;
Primo N. Lara Jr.
1
;
David R. Gandara
1
;
Roman Perez-Soler
2
关键词:
EGFR wild type
;
Multiplex genotyping
;
Plasma circulating tumor DNA
;
Randomized phase 2 study
;
Second line
刊名:Clinical Lung Cancer
出版年:2017
10.
Multifunctions of dietary polyphenols in the regulation of intestinal inflammation
作者:
Makoto Shimizu
;
ms205346@nodai.ac.jp
关键词:
epithelial
cell
;
functional food
;
intestinal inflammation
;
polyphenol
刊名:Journal of Food and Drug Analysis
出版年:2017
1
2
3
4
5
6
7
8
9
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