设为首页
收藏本站
网站地图
|
English
|
公务邮箱
About the library
Background
History
Leadership
Organization
Readers' Guide
Opening Hours
Collections
Help Via Email
Publications
Electronic Information Resources
常用资源
电子图书
期刊论文
学位会议
外文资源
特色专题
内部出版物
Wiley电子期刊(7)
SpringerLink电子期刊(30)
NATURE电子期刊(3)
Elsevier电子期刊(69)
在“
Elsevier电子期刊
”中,
命中:
69
条,耗时:0.1359351 秒
在所有数据库中总计命中:
109
条
1.
Exploring the potential of genome editing
CRISPR
-Cas
9
technology
作者:
Vijai Singh
a
;
vijaisingh15@gmail.com
;
vijai.singh@issb.genopole.fr
;
Darren Braddick
a
;
Pawan Kumar Dhar
b
关键词:
Cas
;
CRISPR
-
associated
protein
s
;
cccDNA
;
covalently closed circular DNA
;
CCR5
;
C-C chemokine receptor type 5
;
CHO
;
Chinese hamster ovary
;
CRISPR
s
;
clustered regularly interspaced short palindromic repeats
;
CRISPR
a
;
CRISPR
activation
;
CRISPR
i
;
CRISPR
interference
;
crRNAs
;
CRISPR
RNAs
;
dCas
9
;
dead Cas
9
;
DMD
;
Duchenne muscular dystrophy
;
DSB
;
double-strand break
;
eGFP
;
enhanced green fluorescent
protein
;
HDR
;
homology-directed repair
;
HEK 2
9
3
;
human embryonic kidney 2
9
3
;
Indel
;
insertion and deleti
刊名:Gene
出版年:2017
2.
Deciphering, Communicating, and Engineering the
CRISPR
PAM
作者:
Ryan T. Leenay
;
Chase L. Beisel
;
cbeisel@ncsu.edu
关键词:
CRISPR
;
clustered regularly interspaced short palindromic repeat
;
Cas
;
CRISPR
-
associated
;
PAM
;
protospacer-adjacent motif
;
crRNAs
;
CRISPR
RNAs
;
PFS
;
protospacer-flanking sequence
;
rPAM
;
RNA PAM
刊名:Journal of Molecular Biology
出版年:2017
3.
Enhanced
CRISPR
/Cas
9
-mediated precise genome editing by improved design and delivery of gRNA, Cas
9
nuclease, and donor DNA
作者:
Xiquan Liang
;
Jason Potter
;
jason.potter@thermofisher.com
;
Shantanu Kumar
;
Namritha Ravinder
;
Jonathan D. Chesnut
关键词:
CRISPR
;
clustered regularly interspaced short palindromic repeats
;
CAS
9
;
CRISPR
associated
protein
;
gRNA
;
guide RNA
;
PAM
;
protospacer adjacent motif
;
RNP
;
ribonucleo
protein
;
HDR
;
homology directed repair
;
hESCs
;
human embryonic stem cells
;
NHEJ
;
non-homologous end joining
;
SNP
;
single-nucleotide polymorphism
刊名:Journal of Biotechnology
出版年:2017
4.
Bioinformatic prediction and functional characterization of human KIAA0100 gene
作者:
He Cui
a
;
1
;
Xi Lan
b
;
1
;
Shemin Lu
b
;
Fujun Zhang
b
;
Wanggang Zhang
a
;
zhangwanggang2003@yahoo.com
关键词:
Human KIAA0100
;
Bioinformatic prediction
;
Acute monocytic leukemia
associated
antigen
;
CRISPR
/Cas
9
system
;
Cell proliferation
;
Cell apoptosis
刊名:Journal of Pharmaceutical Analysis
出版年:2017
5.
Functional genomics provides insights into the role of Propionibacterium freudenreichii ssp. shermanii JS in cheese ripening
作者:
Teija Ojala
a
;
1
;
teija.ojala@helsinki.fi
;
Pia K.S. Laine
a
;
Terhi Ahlroos
b
;
Jarna Tanskanen
b
;
Saara Pitkä
;
nen
b
;
Tuomas Salusjä
;
rvi
b
;
Matti Kankainen
b
;
2
;
Soile Tynkkynen
b
;
Lars Paulin
a
;
Petri Auvinen
a
关键词:
Cas
;
CRISPR
-
associated
protein
;
CDS
;
coding sequence
;
COG
;
clusters of orthologous groups
;
CRISPR
;
clustered regularly interspaced short palindromic repeats
;
EMPP
;
Embden-Meyerhof-Parnas-pathway
;
FDR
;
false discovery rate
;
GI
;
genomic island
;
HGT
;
horizontal gene transfer
;
LAB
;
lactic acid bacteria
;
TCA
;
tricarboxylic acid cycle
;
TU
;
transcription unit
刊名:International Journal of Food Microbiology
出版年:2017
6.
Global transcriptome analysis of Halolamina sp. to decipher the salt tolerance in extremely halophilic archaea
作者:
Aslıhan Kurt-Kızıldoğan
a
;
Bü
;
şra Abanoz
a
;
Sezer Okay
b
;
sezerokay@gmail.com
关键词:
ABC
;
ATP-binding cassette
;
Cas
;
CRISPR
-
associated
protein
;
COGs
;
Cluster of Orthologous Groups
;
CRISPR
;
Clustered regularly interspaced short palindromic repeats
;
DEG
;
Differentially expressed gene
;
GO
;
Gene Ontology
;
KEGG
;
Kyoto Encyclopedia of Genes and Genomes
;
NR
;
Non-redundant
;
NT
;
Nucleotide database
;
qRT-PCR
;
Quantitative real time polymerase chain reaction
;
RNA-seq
;
RNA sequencing
刊名:Gene
出版年:2017
7.
Advances in therapeutic
CRISPR
/Cas
9
genome editing
作者:
Nata&scaron
;
a Savić
;
Gerald Schwank
;
schwankg@ethz.ch" class="auth_mail" title="E-mail the corresponding author
关键词:
Cas
9
;
CRISPR
-
associated
protein
9
;
cccDNA
;
covalently closed circular DNA
;
CCR5
;
chemokine receptor 5
;
CFTR
;
cystic fibrosis transmembrane conductance regulator
;
CRISPR
s
;
clustered regularly interspaced short palindromic repeats
;
crRNA
;
CRISPR
RNA
;
Crygc
;
crystallin
;
gamma C gene
;
DMD
;
Duchenne muscular dystrophy
;
DSBs
;
double-strand breaks
;
FAH
;
fumarylacetoacetate hydrolase
;
HBV
;
hepatitis B virus
;
HDR
;
homology-directed repair
;
HIV
;
human immunodeficiency virus
;
HSPCs
;
hematopoietic stem and
刊名:Translational Research
出版年:2016
8.
CRISPR
-Cas
9
therapeutics in cancer: promising strategies and present challenges
作者:
Lang Yi
;
Jinming Li
;
jmli@nccl.org.cn
关键词:
AAVs
;
adeno-
associated
virus vectors
;
AdV
;
adenoviral
;
BL
;
Burkitt lymphoma
;
CAR
;
chimeric antigen receptor
;
Cas
9
;
CRISPR
-
associated
protein
9
;
CPPs
;
cell-penetrating peptides
;
CRISPR
;
clustered regularly interspaced short palindromic repeat
;
crRNA
;
CRISPR
RNA
;
dCas
9
;
catalytically inactive Cas
9
;
DSBs
;
double strand breaks
;
EBV
;
Epstein-Barr virus
;
FnCas
9
;
Francisella novicida Cas
9
;
GOF
;
gain of function
;
HBV
;
hepatitis B virus
;
HCV
;
hepatitis C virus
;
HDR
;
homologous-directed repair
;
HPV
;
human
刊名:Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
出版年:2016
9.
CRISPR
/Cas
9
-mediated knockout of p22phox leads to loss of Nox1 and Nox4, but not Nox5 activity
作者:
Kim-Kristin Prior
a
;
b
;
Matthias S. Leisegang
a
;
b
;
Ivana Josipovic
a
;
b
;
Oliver Lö
;
we
a
;
b
;
Ajay M. Shah
d
;
Norbert Weissmann
c
;
Katrin Schrö
;
der
a
;
b
;
Ralf P. Brandes
a
;
b
;
brandes@vrc.uni-frankfurt.de" class="auth_mail" title="E-mail the corresponding author
关键词:
CRISPR
;
Clustered regulatory interspaced short palindromic repeats
;
Cas
9
;
CRISPR
-
associated
protein
9
;
HEK2
9
3
;
human embryonic kidney 2
9
3 cells
;
HRP
;
horseradish peroxidase
;
Nox4-HEK2
9
3
;
HEK2
9
3 cells stably expressing Nox4
;
PMA
;
phorbol 12-myristate 13-acetate
;
tetNox4-HEK2
9
3
;
HEK2
9
3 cells expressing Nox4 in tetracycline-inducible tet-on vector
刊名:Redox Biology
出版年:2016
10.
CRISPR
/Cas
9
genome editing of rubber producing dandelion Taraxacum kok-saghyz using Agrobacterium rhizogenes without selection
作者:
Brian Iaffaldano
;
Yingxiao Zhang
;
Katrina Cornish
;
cornish.1
9
@osu.edu" class="auth_mail" title="E-mail the corresponding author
关键词:
TK
;
Taraxacum kok-saghyz
;
1-FFT
;
fructan
;
fructan 1-fructosyltransferase
;
ZFNs
;
zinc finger nucleases
;
TALENs
;
transcription activator-like effector nucleases
;
CRISPR
;
clustered regularly interspaced short palindromic repeats
;
Cas
9
;
CRISPR
associated
protein
9
;
QTLs
;
quantitative trait loci
;
PEG
;
polyethylene glycol
;
1/2 MS
;
half-strength Murashige and Skoog medium
;
sgRNA
;
single guide RNA
;
CTAB
;
cetyl trimethyl ammonium bromide
;
PCR
;
polymerase chain reaction
;
InDels
;
insertions and deletions
;
P
刊名:Industrial Crops & Products
出版年:2016
1
2
3
4
5
6
7
按检索点细分(69)
题名(4)
关键词(23)
文摘(42)
按出版年细分(69)
2027年及以后(5)
2017年(6)
2016年(30)
2015年(7)
2013年(6)
2012年(6)
2011年(2)
2010年(1)
2009年(6)
NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via
email
.