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Elsevier电子期刊(1303)
在“
Elsevier电子期刊
”中,
命中:
1,303
条,耗时:小于0.01 秒
在所有数据库中总计命中:
1,303
条
1.
Metabolic-induced cytotoxicity of diosbulbin B in
CYP3A4
-expressing cells
作者:
Ji-zong Jiang
a
;
Bao-hua Yang
a
;
Li-li Ji
a
;
b
;
Li Yang
a
;
b
;
Yu-Chang Mao
c
;
Zhuo-han Hu
c
;
Zheng-tao Wang
a
;
b
;
Chang-hong Wang
a
;
b
;
wchcxm@hotmail.com
关键词:
AP
;
Acetaminophen
;
CCK
;
2H&ndash
;
Tetrazolium
;
5-(2
;
4-disulfophenyl)-3-(2-methoxy&ndash
;
4-nitrophenyl)&ndash
;
2-(4-nitrophenyl)-
;
innersalt
;
sodium salt
;
CYP450
;
Cytochrome P450
;
DB
;
Diosbulbin B
;
DMEM
;
Dulbecco's Modified Eagle Medium
;
DMF
;
N
;
N-Dimethylformamide
;
DMSO
;
Dimethyl Sulphoxide
;
FBS
;
Fetal bovine serum
;
GSH
;
Glutathione
;
IS
;
Internal standard
;
KT
;
ketoconazole
;
MLM
;
Mouse liver microsomes
;
MRM
;
Multiple reaction mode
;
MS/MS
;
Mass spectrometry tandem and mass spectrometry
;
MTT
;
3-(4
;
5-Dime
刊名:Toxicology in Vitro
出版年:2017
2.
Effects of triazole fungicides on androgenic disruption and
CYP3A4
enzyme activity
作者:
Xuan Lv
a
;
b
;
Liumeng Pan
a
;
Jiaying Wang
a
;
Liping Lu
a
;
b
;
Weilin Yan
a
;
c
;
Yanye Zhu
a
;
Yiwen Xu
a
;
Ming Guo
d
;
Shulin Zhuang
a
;
b
;
shulin@zju.edu.cn
关键词:
Triazole
;
Androgen receptor
;
Metabolism
;
CYP450
;
Steroid hormone
刊名:Environmental Pollution
出版年:2017
3.
Benzotriazole UV 328 and UV-P showed distinct antiandrogenic activity upon human
CYP3A4
-mediated biotransformation
作者:
Shulin Zhuang
a
;
b
;
shulin@zju.edu.cn
;
Xuan Lv
a
;
c
;
Liumeng Pan
a
;
Liping Lu
a
;
Zhiwei Ge
a
;
Jiaying Wang
a
;
Jingpeng Wang
a
;
Jinsong Liu
d
;
Weiping Liu
a
;
Chunlong Zhang
e
;
zhang@uhcl.edu
关键词:
Benzotriazole UV stabilizers
;
Androgen receptor
;
Metabolism
;
Molecular modeling
;
Mass spectrometry
刊名:Environmental Pollution
出版年:2017
4.
Effect of cholecystectomy on bile acids as well as relevant enzymes and transporters in mice: Implication for pharmacokinetic changes of rifampicin
作者:
Fan Zhang
a
;
b
;
Hongyan Qin
b
;
Yanshu Zhao
a
;
b
;
Yuhui Wei
b
;
Lili Xi
b
;
Zhi Rao
b
;
Jianping Zhang
b
;
Yanrong Ma
b
;
Yingting Duan
a
;
b
;
Xinan Wu
b
;
xinanwu6511@126.com
关键词:
Asbt
;
apical sodium-dependent bile acids transporter
;
BAs
;
bile acids
;
Bsep
;
bile salt export pump
;
β-MCA
;
β-muricholic acid
;
CA
;
cholic acid
;
CDCA
;
chenodeoxycholic acid
;
Cyp3a11
;
cytochrome P450 3a11 (human
CYP3A4
)
;
Cyp7a1
;
cholesterol 7α-hydroxylase cytochrome P450 7a1
;
DCA
;
deoxycholic acid
;
Fxr
;
farnesoid X receptor
;
G-
;
glycine conjugated bile acid
;
HDCA
;
hyodesoxycholic acid
;
LCA
;
lithocholic acid
;
Mrp2
;
multidrug resistance-associated protein 2
;
NDCA
;
demethylation deoxycholic acid
;
NRs
刊名:European Journal of Pharmaceutical Sciences
出版年:2017
5.
Targeting calcium signaling in cancer therapy
作者:
Chaochu Cui
a
;
b
;
Robert Merritt
b
;
c
;
Liwu Fu
a
;
Zui Pan
b
;
c
;
d
;
zui.pan@uta.edu
关键词:
20-GPPD
;
20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol
;
CaM
;
calmodulin
;
CaMKII
;
calmodulin-dependent protein kinase II
;
CBD
;
cannabidiol
;
CBG
;
cannabigerol
;
CPZ
;
capsazepine
;
CRAC
;
Ca2+ release-activated Ca2+ channel
;
CTL
;
cytotoxic T cells
;
CYP3A4
;
cytochrome P450 3A4
;
ER/SR
;
endoplasmic/sarcoplasmic reticulum
;
HCX
;
H+/Ca2+ exchangers
;
IP3
;
inositol 1
4 ;
5-trisphosphate
;
IP3R (1
;
2
;
3)
;
IP3 receptor (type 1
;
type 2
;
type 3)
;
mAb
;
monoclonal antibody
;
MCU
;
mitochondrial Ca2+ uniporter
;
MCUR1
;
MC
刊名:Acta Pharmaceutica Sinica B
出版年:2017
6.
Clementine juice has the potential for drug interactions - In vitro comparison with grapefruit and mandarin juice
作者:
Dirk Theile
a
;
1
;
Nicolas Hohmann
a
;
1
;
Dominik Kiemel
a
;
Giuseppe Gattuso
b
;
Davide Barreca
b
;
Gerd Mikus
a
;
Walter Emil Haefeli
a
;
Vedat Schwenger
c
;
d
;
1
;
Johanna Weiss
a
;
1
;
johanna.weiss@med.uni-heidelberg.de
关键词:
Clementine
;
CYPs
;
Drug transporters
;
Grapefruit
;
Mandarin
;
HPLC-DAD-ESI-MS-MS
刊名:European Journal of Pharmaceutical Sciences
出版年:2017
7.
Role of
CYP3A4
in losartan-induced cytotoxicity and its glutathione adducts formation
作者:
Chang Seon Ryu
1
;
2
;
Ji-Yoon Lee
1
;
Jang Su Jeon
1
;
Kwon Bok Kim
3
;
Sang Kyum Kim
1
刊名:Drug Metabolism and Pharmacokinetics
出版年:2017
8.
Use of mRNA suppression to estimate
CYP3A4
protein degradation rate constant in primary human hepatocytes
作者:
Christina Y. Chan
1
;
Owain Roberts
1
;
Nadeem Hassan
1
;
Neill Liptrott
1
;
Marco Siccardi
1
;
Lisa Almond
2
;
Andrew Owen
1
刊名:Drug Metabolism and Pharmacokinetics
出版年:2017
9.
Reversible and time-dependent inhibition (TDI) of CYP1A2, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6 and
CYP3A4
in human hepatocyte suspensions by model inhibitors
作者:
J. George Zhang
;
Thuy Ho
;
Reena Patel
;
Sarah K. Trisdale
;
Tim Creegan
;
David M. Stresser
刊名:Drug Metabolism and Pharmacokinetics
出版年:2017
10.
The in vitro evaluation of ketoconazole and its alternative clinical
CYP3A4
/5 inhibitors (ritonavir, clarithromycin and itraconazole) as inhibitors of non-CYP enzymes
作者:
David B. Buckley
;
Brian W. Ogilvie
;
Phyllis Yerino
刊名:Drug Metabolism and Pharmacokinetics
出版年:2017
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