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1.Genetic instability, CpG island methylator phenotype, and proliferative activity are distinct differences between diminutive and small tubular adenoma of the colorectum

作者：Yoshiki Nando ; MD^a ; Jiro Watari ; MD ; PhD^a ; ^{watarij@hyo-med.ac.jp} ; Chiyomi Ito ; LA^a ; Ken Hara ; MD ; PhD^a ; Takahisa Yamasaki ; MD ; PhD^a ; Takuya Okugawa ; MD ; PhD^a ; Takashi Kondo ; MD ; PhD^a ; Tomoaki Kono ; MD ; PhD^a ; Katsuyuki Tozawa ; MD ; PhD^a ; Toshihiko Tomita ; MD ; PhD^a ; Yoshio Ohda ; MD ; PhD^a ; Tadayuki Oshima ; MD ; PhD^a ; Hirokazu Fukui ; MD ; PhD^a ; Nagahide Matsubara ; MD ; PhD^b ; Naohiro Tomita ; MD ; PhD^b ; Seiichi Hirota ; MD ; PhD^c ; Hiroto Miwa ; MD ; PhD^a

关键词：Colorectal tubular adenoma ; CpG island methylator phenotype ; Genetic instability ; KRAS ; BRAF

刊名：Human Pathology

出版年：2017

2.Are clinicopathological features of colorectal cancers with methylation in half of CpG island methylator phenotype panel markers different from those of CpG island methylator phenotype-high colorectal cancers?

作者：Jeong Mo Bae ; MD^a ; ¹ ; ^{jeongmobae@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Ye-Young Rhee ; MD^a ; ¹ ; ^{songyyii@naver.com" class="auth_mail" title="E-mail the corresponding author} ; Kyung Ju Kim ; MD^a ; ^{sonicker@naver.com" class="auth_mail" title="E-mail the corresponding author} ; Xianyu Wen ; MSc^a ; ^b ; ^{hyunwoo625@snu.ac.kr" class="auth_mail" title="E-mail the corresponding author} ; Young Seok Song ; MSc^b ; ^{suky0215@naver.com" class="auth_mail" title="E-mail the corresponding author} ; Nam-Yun Cho ; MSc^b ; ^{chonamyun@hanmail.net" class="auth_mail" title="E-mail the corresponding author} ; Jung Ho Kim ; MD ; PhD^a ; Gyeong Hoon Kang ; MD ; PhD^a ; ^b ; ^{ghkang@snu.ac.kr" class="auth_mail" title="E-mail the corresponding author}

关键词：Colorectal cancer ; CpG island methylator phenotype ; DNA methylation ; Marker ; Prognosis

刊名：Human Pathology

出版年：2016

3.Targeting the serrated pathway of colorectal cancer with mutation in BRAF

作者：Paulo Matos^a ; ^b ; ^c ; Vâ ; nia Gonç ; alves^b ; ^c ; Peter Jordan^b ; ^c ; ^{peter.jordan@insa.min-saude.pt" class="auth_mail" title="E-mail the corresponding author}

关键词：BRAF ; Colorectal cancer ; RAC1b ; Serrated pathway ; Tumor growth ; Therapeutic target

刊名：Biochimica et Biophysica Acta (BBA)-Reviews on Cancer

出版年：2016

4.DNA methylation changes in epithelial ovarian cancer histotypes

作者：Madalene A. Earp^a ; Julie M. Cunningham^b ; ^{cunningham.julie@mayo.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：EOC ; epithelial ovarian cancer ; EN ; endometrioid ; CC ; clear cell ; MC ; mucinous ; HG ; high-grade ; LG ; low-grade ; CGI ; CpG Island ; CIMP ; CpG Island methylation phenotype ; SBT ; serous borderline tumor ; TSG ; tumor suppressor gene ; MMR ; mismatch repair ; MSI ; microsatellite instability

刊名：Genomics

出版年：2015

5.Genetic and epigenetic variants in the MTHFR gene are not associated with non-Hodgkin lymphoma

作者：Gabrielle Bradshaw ; Heidi G. Sutherland ; Emily T. Camilleri ; Rodney A. Lea ; Larisa M. Haupt ; Lyn R. Griffiths ; ^{lyn.griffiths@qut.edu.au" class="auth_mail" title="E-mail the corresponding author}

关键词：Bp ; base pairs ; CGIs ; CpG Islands ; CIMP ; CpG island methylator phenotype ; DLBCL ; diffuse large b-cell lymphoma ; DNA ; deoxyribose nucleic acid ; EDTA ; ethylenediaminetetra acetic acid ; FL ; follicular lymphoma ; HRM ; high resolution melt ; MTHFR ; methylenetetrahydrofolate reductase ; NHL ; non-Hodgkin lymphoma ; OR ; odds ratio ; PCR ; polymerase chain reaction ; RFLP ; restriction fragment length polymorphism ; SD ; standard deviation ; SNP ; single nucleotide polymorphism ; THF ; tetrahydrofolate ; WHO ; World Hea

刊名：Meta Gene

出版年：2015

6.The impact of the Cancer Genome Atlas on lung cancer

作者：Jeremy T.-H. Chang^a ; Yee Ming Lee^b ; R. Stephanie Huang^c ; ^{rhuang@medicine.bsd.uchicago.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：CIMP ; CpG island methylator phenotype ; GSEA ; gene set enrichment analysis ; LUAD ; lung adenocarcinoma ; LUSC ; lung squamous cell carcinoma ; miRNA ; microRNA ; NSCLC ; non-small cell lung carcinoma ; OS ; overall survival ; TCGA ; the Cancer Genome Atlas

刊名：Translational Research

出版年：2015

7.Comprehensive DNA methylation and extensive mutation analyses reveal an association between the CpG island methylator phenotype and oncogenic mutations in gastric cancers

作者：Jeong Goo Kim^a ; ^b ; Hideyuki Takeshima^a ; Tohru Niwa^a ; Emil Rehnberg^a ; Yasuyuki Shigematsu^a ; Yukie Yoda^a ; ^c ; Satoshi Yamashita^a ; Ryoji Kushima^d ; Takao Maekita^e ; Masao Ichinose^e ; Hitoshi Katai^c ; Won Sang Park^f ; Young Seon Hong^g ; Cho Hyun Park^b ; ; Toshikazu Ushijima^a ; ^{tushijim@ncc.go.jp}

关键词：GC ; gastric cancer ; CGI ; CpG island ; H. pylori ; Helicobacter pylori ; CIMP ; CpG island methylator phenotype ; EB virus ; Epstein&ndash ; Barr virus ; TSS ; transcription start site ; COSMIC ; Catalogue Of Somatic Mutations In Cancer

刊名：Cancer Letters

出版年：2013

8.CpG Island Methylator Phenotype Is Associated With Response to Adjuvant Irinotecan-Based Therapy for Stage III Colon Cancer

作者：Stacey Shiovitz¹ ; ² ; ^&lowast ; ; Monica M. Bertagnolli³ ; ^&lowast ; ; Lindsay A. Renfro⁴ ; Eunmi Nam⁵ ; Nathan R. Foster⁴ ; Slavomir Dzieciatkowski² ; Yanxin Luo² ; ⁶ ; Victoria Valinluck Lao² ; ⁷ ; Raymond J. Monnat Jr.⁸ ; Mary J. Emond⁹ ; Nancy Maizels¹⁰ ; Donna Niedzwiecki¹¹ ; Richard M. Goldberg¹² ; Leonard B. Saltz¹³ ; Alan Venook¹⁴ ; Robert S. Warren¹⁴ ; William M. Grady¹ ; ² ; ^{wgrady@fhcrc.org" class="auth_mail" title="E-mail the corresponding author} ; for the Alliance for Clinical Trials in Oncology

关键词：CALGB (Alliance) 89803 ; CRC ; Epigenetic Factors ; Chemotherapy

刊名：Gastroenterology

出版年：2014

9.Epigenetic modifications in colorectal cancer: Molecular insights and therapeutic challenges

作者：Aristeidis G. Vaiopoulos¹ ; Kalliopi Ch. Athanasoula¹ ; Athanasios G. Papavassiliou ; ^{papavas@med.uoa.gr" class="auth_mail}

关键词：5-FU ; fluorouracil ; A ; acetyl-groups ; ALDH1 ; aldehyde dehydrogenase-1 ; AP-1 ; activator protein 1 ; APC ; adenomatous polyposis coli ; ASO ; anti-sense oligonucleotides ; Bmi1 ; B lymphoma Mo-MLV insertion region 1 homolog ; BMP ; bone morphogenetic protein ; CSC ; cancer stem cell ; CBP ; CREB-binding protein ; CDH1 ; cadherin-1 ; CDKN2A ; cyclin-dependent kinase inhibitor 2A ; CDX1 ; caudal type homeobox-1 ; CGI ; CpG islands ; CIMP ; CpG island methylator phenotype ; CIN ; chromosomal instability ; CpG ; cytosine guani

刊名：Biochimica et Biophysica Acta (BBA)/Molecular Basis of Disease

出版年：July 2014

10.Epigenetic biomarkers in skin cancer

作者：Edward S. Greenberg ; Kelly K. Chong ; Kelly T. Huynh ; Ryo Tanaka ; Dave S.B. Hoon

关键词：BC ; biochemotherapy ; BCC ; basal cell carcinoma ; BM ; biomarker ; SBM ; sodium bisulfite modification ; CAE ; capillary array electrophoresis ; cf-CNA ; cell-free circulating nucleic acid ; ChIP ; chromatin immunoprecipitation ; CIMP ; CpG island methylator phenotype ; CoBRA ; combined bisulfite restriction analysis ; CTC ; circulating tumor cell ; CTCL ; cutaneous T-cell lymphoma ; DNMT ; DNA methyltransferase ; IHC ; immunohistochemistry ; LINE-1 ; long interspersed nuclear element-1 ; MCC ; merkel cell carcinoma ; MINT

刊名：Cancer Letters

出版年：28 January, 2014

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