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Elsevier电子期刊(5)
ACS电子期刊(3)
在“
Elsevier电子期刊
”中,
命中:
5
条,耗时:小于0.01 秒
在所有数据库中总计命中:
8
条
1.
Identification of a selective inhibitor of murine intestinal alkaline phosphatase (ML260) by concurrent ultra-high throughput screening against human and mouse isozymes
作者:
Robert J. Ardecky
;
Ekaterina V. Bobkova
;
Tina Kiffer-Moreira
;
Brock Brown
;
Santhi Ganji
;
Jiwen Zou
;
Ian Pass
;
Sonoko Narisawa
;
Fl谩via Godoy Iano
;
Craig
Rosenstein
;
Anton Cheltsov
;
Justin Rascon
;
Michael Hedrick
;
Carlton Gasior
;
Anita Forster
;
Shenghua Shi
;
Russell Dahl
;
Stefan Vasile
;
Ying Su
;
Eduard Sergienko
;
Thomas D.Y. Chung
;
et al.
关键词:
Alkaline phosphatase
;
Inhibitors
;
Enzymes
;
Intestinal alkaline phosphatase
;
Inflammatory bowel disease
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:1 February, 2014
2.
Thiophene carboxamide inhibitors of JAK2 as potential treatments for myleoproliferative neoplasms
作者:
Andrew M. Haidle
a
;
andrew_haidle@merck.com" class="auth_mail
;
Anna A. Zabierek
a
;
Kaleen K. Childers
a
;
Craig
Rosenstein
b
;
Anjili Mathur
c
;
Michael D. Altman
a
;
Grace Chan
b
;
Lin Xu
d
;
Eric Bachman
c
;
Jan-Rung Mo
c
;
Melaney Bouthillette
e
;
Thomas Rush
a
;
Paul Tempest
a
;
C. Gary Marshall
f
;
Jonathan R. Young
a
关键词:
JAK2
;
Polycythemia vera
;
Bioisostere
;
Metabolite identification
;
Thiophene
;
Protein kinase
;
Inhibitor
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:15 April, 2014
3.
The discovery of reverse tricyclic pyridone JAK2 inhibitors. Part 2: Lead optimization
作者:
Tony Siu
a
;
tony_siu@merck.com" class="auth_mail
;
Sathyajith E. Kumarasinghe
a
;
Michael D. Altman
b
;
Matthew Katcher
a
;
Alan Northrup
a
;
Catherine White
a
;
Craig
Rosenstein
c
;
Anjili Mathur
d
;
Lin Xu
e
;
Grace Chan
c
;
Eric Bachman
d
;
Melaney Bouthillette
f
;
Christopher J. Dinsmore
a
;
C. Gary Marshall
g
;
Jonathan R. Young
a
关键词:
JAK2
;
Kinases
;
Water interaction
;
Kinase selectivity
;
Ligand binding affinity
;
Kinase partition index
;
Molecular modeling
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:15 March, 2014
4.
A genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity
作者:
Gillian C. Barnett
a
;
b
;
gillbarnett@doctors.org.uk" class="auth_mail
;
Deborah Thompson
a
;
Laura Fachal
c
;
Sarah Kerns
d
;
Chris Talbot
e
;
Rebecca M. Elliott
f
;
Leila Dorling
a
;
Charlotte E. Coles
g
;
David P. Dearnaley
h
;
Barry S.
Rosenstein
d
;
Ana Vega
c
;
Paul Symonds
i
;
John Yarnold
h
;
Caroline Baynes
a
;
Kyriaki Michailidou
a
;
Joe Dennis
a
;
Jonathan P. Tyrer
a
;
Jennifer S. Wilkinson
g
;
Antonio Gó
;
mez-Caamañ
;
o
j
;
George A. Tanteles
k
;
Radka Platte
a
;
Rebecca Mayes
a
;
Don Conroy
a
;
Mel Maranian
a
;
Craig
Luccarini
a
;
Sarah L. Gulliford
h
;
Matthew R. Sydes
l
;
Emma Hall
m
;
Joanne Haviland
m
;
Vivek Misra
n
;
Jennifer Titley
m
;
Sø
;
ren M. Bentzen
o
;
Paul D.P. Pharoah
a
;
Neil G. Burnet
b
;
1
;
Alison M. Dunning
a
;
1
;
Catharine M.L. West
f
;
1
关键词:
Radiotherapy
;
Late toxicity
;
Adverse effects
;
Genetics
;
Genome-wide association scan
刊名:Radiotherapy and Oncology
出版年:May 2014
5.
The discovery of tricyclic pyridone JAK2 inhibitors. Part 1: Hit to lead
作者:
Tony Siu
;
Ekaterina S. Kozina
;
Joon Jung
;
Craig
Rosenstein
;
Anjili Mathur
;
Michael D. Altman
;
Grace Chan
;
Lin Xu
;
Eric Bachman
;
Jan-Rung Mo
;
Melaney Bouthillette
;
Thomas Rush
;
Christopher J. Dinsmore
关键词:
JAK2
;
Kinase
;
Ligand binding efficiency
;
Structure based design
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2010
1
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2027年及以后(1)
2010年(1)
2000年及以前(3)
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