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Wiley电子期刊(58)
SpringerLink电子期刊(1731)
Elsevier电子期刊(3871)
Springer电子图书(7)
NATURE电子期刊(21)
ACS电子期刊(417)
在“
Elsevier电子期刊
”中,
命中:
3,871
条,耗时:0.0269827 秒
在所有数据库中总计命中:
6,105
条
1.
Discovery and preclinical evaluation of 7-benzyl-N-(substituted)-pyrrolo[3,2-d]pyrimidin-4-amines as single
agents
with microtubule targeting effects along with triple-acting angiokinase inhibition as antitumor
agents
作者:
Roheeth Kumar Pavana
a
;
Shruti Choudhary
a
;
Anja Bastian
b
;
Michael A. Ihnat
c
;
Ruoli Bai
d
;
Ernest Hamel
d
;
Aleem Gangjee
a
;
gangjee@duq.edu
关键词:
AA
;
antiangiogenic
agents
;
MTA
;
microtubule targeting
agents
;
VEGFR-2
;
vascular endothelial growth factor receptor-2
;
PDGFR-β
;
platelet-derived growth factor receptor-β
;
CAM
;
chorioallantoic membrane
;
CA
;
combretastatin A-4
;
Pgp
;
P-glycoprotein
;
EGFR
;
epidermal growth factor receptor
;
TBS
;
Tris-buffered saline
;
HRP
;
horseradish peroxidase
;
PY
;
phosphotyrosine
刊名:Bioorganic & Medicinal Chemistry
出版年:2017
2.
Synthesis, evaluation and quantitative structure-activity relationship (QSAR) analysis of Wogonin derivatives as
cytotoxic
agents
作者:
Jinlei Bian
1
;
Tinghan Li
1
;
Tianwei Weng
;
Jubo Wang
;
Yu Chen
;
Zhiyu Li
;
zhiyuli@cpu.edu.cn
关键词:
Wogonin
;
QSAR
;
Cytotoxic
;
Flavonoid
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2017
3.
New approach of delivering
cytotoxic
drugs towards CAIX expressing cells: A concept of dual-target drugs
作者:
Simon J.A. van Kuijk
a
;
1
;
s.vankuijk@maastrichtuniversity.nl
;
Nanda Kumar Parvathaneni
a
;
b
;
1
;
nanda-kumar.parvathaneni@etu.umontpellier.fr
;
Raymon Niemans
a
;
1
;
Marike W. van Gisbergen
a
;
1
;
Fabrizio Carta
c
;
Daniela Vullo
d
;
Silvia Pastorekova
e
;
Ala Yaromina
a
;
Claudiu T. Supuran
c
;
Ludwig J. Dubois
a
;
2
;
Jean-Yves Winum
b
;
2
;
Philippe Lambin
a
;
2
关键词:
Tumor
;
Hypoxia
;
Carbonic anhydrase IX
;
Dual-target drugs
;
CAIX inhibitors
;
Cytotoxic
drugs
刊名:European Journal of Medicinal Chemistry
出版年:2017
4.
Synthesis of hydroxycinnamic acid derivatives as mitochondria-targeted antioxidants and
cytotoxic
agents
作者:
Jiyu Li
a
;
&dagger
;
;
Dian He
a
;
&dagger
;
;
Baitao Wang
a
;
Ling Zhang
a
;
Kun Li
a
;
Qinjian Xie
b
;
Lifang Zheng
a
;
zhenglf@lzu.edu.cn
关键词:
Mitochondrial dysfunction
;
Hepatocellular carcinomas
;
Hydroxycinnamic acids
;
Antiproliferative activities
;
Mitochondrial permeability transition pore
刊名:Acta Pharmaceutica Sinica B
出版年:2017
5.
Cytotoxic
activity, apoptosis induction and structure-activity relationship of 8-OR-2-aryl-3,4-dihydroisoquinolin-2-ium salts as promising anticancer
agents
作者:
Fang-Jun Cao
1
;
Li-Fei Zhu
1
;
Qian Kuang
;
Xing-Qiang Li
;
Bo-Hang Zhou
;
Xin-Juan Yang
;
yxjsn2@163.com
;
Le Zhou
;
zhoulechem@nwsuaf.edu.cn
关键词:
Isoquinoline
;
Benzo[c]phenanthridine alkaloid
;
Cytotoxic
ity
;
Apoptosis induction
;
Structure&ndash
;
activity relationship
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2017
6.
Facile synthesis and antiproliferative activity of 7H-benzo[7,8]chromeno[2,3-d]pyrimidin-8-amines
作者:
Hamidreza Akrami
a
;
Maliheh Safavi
b
;
Bibi Fatemeh Mirjalili
a
;
Mahmood Dehghani Ashkezari
c
;
Farhang Dadfar
c
;
Najme Mohaghegh
a
;
Saeed Emami
d
;
Fahimeh Salehi
e
;
Hamid Nadri
f
;
Sussan K. Ardestani
e
;
Loghman Firoozpour
g
;
Mehdi Khoobi
h
;
i
;
khoobi@tums.ac.ir
;
Alireza Foroumadi
g
;
h
;
aforoumadi@yahoo.com
关键词:
Anticancer
;
Cytotoxic
agents
;
Benzochromene
;
Polycyclic compounds
刊名:European Journal of Medicinal Chemistry
出版年:2017
7.
Real-time near-infrared bioimaging of a receptor-targeted
cytotoxic
dendritic theranostic agent
作者:
Junchen Wu
;
Yuren Zhou
;
Shang Li
;
Dahui Qu
;
Wei-Hong Zhu
;
whzhu@ecust.edu.cn
;
He Tian
关键词:
Substance P
;
5-fluorouracil
;
Neurokinin-1 receptor
;
Near-infrared imaging
;
Anticancer
刊名:Biomaterials
出版年:2017
8.
Multifunctional gold-nanoparticles: A nanovectorization tool for the targeted delivery of novel chemotherapeutic
agents
作者:
Alexandra R. Fernandes
a
;
b
;
ma.fernandes@fct.unl.pt
;
Joã
;
o Jesus
a
;
Pedro Martins
a
;
Sara Figueiredo
a
;
Daniela Rosa
a
;
Luí
;
sa M.R.D.R.S. Martins
b
;
c
;
Maria Luí
;
sa Corvo
d
;
Manuela C. Carvalheiro
d
;
Pedro M. Costa
e
;
Pedro V. Baptista
a
;
pmvb@fct.unl.pt
关键词:
Gold nanoparticles
;
Targeting
;
Nanomedicine
;
Cancer therapy
;
Metal complexes
;
Colorectal cancer
;
Lung cancer
刊名:Journal of Controlled Release
出版年:2017
9.
Design, synthesis, docking and QSAR study of substituted benzimidazole linked oxadiazole as
cytotoxic
agents
, EGFR and erbB2 receptor inhibitors
作者:
Md Jawaid Akhtar
a
;
Anees Ahmad Siddiqui
a
;
Ahsan Ahmed Khan
a
;
Zulphikar Ali
a
;
Rikeshwer Prasad Dewangan
b
;
Santosh Pasha
b
;
M. Shahar Yar
a
;
yarmsy@rediffmail.com
关键词:
Benzimidazole linked oxadiazole
;
Anticancer
;
Apoptosis
;
3D-QSAR studies
刊名:European Journal of Medicinal Chemistry
出版年:2017
10.
Quinolidene based monocarbonyl curcumin analogues as promising antimycobacterial
agents
: Synthesis and molecular docking study
作者:
Dnyaneshwar D. Subhedar
a
;
Mubarak H. Shaikh
a
;
Laxman Nawale
b
;
Dhiman Sarkar
b
;
Vijay M. Khedkar
b
;
Bapurao B. Shingate
a
;
bapushingate@gmail.com
关键词:
Antitubercular activity
;
Cytotoxic
ity
;
Green protocol
;
Knoevenagel condensation
;
Molecular docking
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2017
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