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Elsevier电子期刊(24)

在“Elsevier电子期刊”中，命中：24条，耗时：小于0.01 秒

在所有数据库中总计命中：64条

1.Novel antibody drug conjugates containing exatecan derivative-based cytotoxic payloads

作者：Takashi Nakada ; ^{nakada.takashi.g6@daiichisankyo.co.jp" class="auth_mail" title="E-mail the corresponding author} ; Takeshi Masuda ; Hiroyuki Naito ; Masao Yoshida ; Shinji Ashida ; Koji Morita ; Hideki Miyazaki ; Yuji Kasuya ; Yusuke Ogitani ; Junko Yamaguchi ; Yuki Abe ; Takeshi Honda

关键词：Antibody drug conjugate ; Camptothecin ; Exatecan ; Cytotoxic payload ; Linker ; Anti-HER2 ; Trastuzumab ; Oncology ; Cancer therapy

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

2.Sequential release of nanoparticle payloads from ultrasonically burstable capsules

作者：Stephen Kennedy^a ; ^b ; ^c ; ¹ ; Jennifer Hu^a ; ¹ ; Cathal Kearney^a ; ^d ; Hadas Skaat^a ; Luo Gu^a ; Marco Gentili^a ; Herman Vandenburgh^e ; ^f ; David Mooney^a ; ^{mooneyd@seas.harvard.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Ultrasound response ; Drug delivery ; Biomaterials ; Controlled release

刊名：Biomaterials

出版年：2016

3.Analogues of DNA minor groove cross-linking agents incorporating aminoCBI, an amino derivative of the duocarmycins: Synthesis, cytotoxicity, and potential as payloads for antibody-drug conjugates

作者：Anna C. Giddens^a ; Ho H. Lee^a ; Guo-Liang Lu^a ; Christian K. Miller^a ; Jun Guo^b ; Gail D. Lewis Phillips^b ; Thomas H. Pillow^b ; Moana Tercel^a ; ^{m.tercel@auckland.ac.nz" class="auth_mail" title="E-mail the corresponding author}

关键词：ADC ; antibody&ndash ; drug conjugate ; BINAP ; 2 ; 2&prime ; -bis(diphenylphosphino)-1 ; 1&prime ; -binaphthalene ; CBI ; 129 ; 9a-tetrahydrocyclopropa[c]benz[e]indol-4-one ; EDCI ; N-ethyl-N&prime ; -(3-dimethylaminopropyl)carbodiimide hydrochloride ; MMAE ; monomethyl auristatin E ; PBD ; pyrrolobenzodiazepine ; Pgp ; P-glycoprotein

刊名：Bioorganic & Medicinal Chemistry

出版年：2016

4.Chromatography-based methods for determining molar extinction coefficients of cytotoxic payload drugs and drug antibody ratios of antibody drug conjugates

作者：Chunlei Wang ; ^{chunlei.wang@bms.com" class="auth_mail" title="E-mail the corresponding author} ; Sike Chen ; Janet Caceres-Cortes ; Richard Y.-C. Huang ; Adrienne A. Tymiak ; Yingru Zhang

关键词：Molar extinction coefficient (MEC) ; Drug antibody ratio (DAR) ; Chemiluminescence nitrogen detector (CLND) ; Antibody drug conjugate (ADC) ; UV spectrophotometry

刊名：Journal of Chromatography A

出版年：2016

5.Antibody-drug conjugates: Current status and future perspectives

作者：Ré ; my Gé ; bleux^a ; Giulio Casi^b ; ^{giulio.casi@sennchem.com" class="auth_mail" title="E-mail the corresponding author}

关键词：ADCs ; antibody-drug-conjugates ; ALL ; acute lymphocytic leukemia ; AML ; acute myeloid leukemia ; B-NHL ; B-cell non-Hodgkin's lymphoma ; ccRCC ; clear cell renal cell carcinoma ; DLBCL ; diffuse large B-cell lymphoma ; DAR ; drug to antibody ratio ; ECM ; extra cellular matrix ; GO ; Gemtuzumab ozogamicin ; IgG ; Immunoglobulin G ; mAb ; monoclonal antibody ; MDR ; multidrug resistance ; MTD ; maximum tolerated dose ; NHL ; non-Hodgkin lymphoma ; ORR ; overall response rate ; PBD ; pyrrolobenzodiazepines

刊名：Pharmacology and Therapeutics

出版年：2016

6.Combining antibody-drug conjugates and immune-mediated cancer therapy: What to expect?

作者：Hans-Peter Gerber ; ^{hanspeter.gerber@pfizer.com" class="auth_mail" title="E-mail the corresponding author} ; Puja Sapra ; Frank Loganzo ; Chad May

关键词：Immune-checkpoint inhibitors ; Antibody&ndash ; drug conjugate ; Immunogenic cell death ; Immuno-onocology ; Combination treatment

刊名：Biochemical Pharmacology

出版年：2016

7.Nanomedicine in the development of anti-HIV microbicides

作者：José ; das Neves^a ; ^b ; ^c ; ^{j.dasneves@ineb.up.pt" class="auth_mail" title="E-mail the corresponding author} ; Rute Nunes^a ; ^b ; ^d ; Francisca Rodrigues^e ; Bruno Sarmento^a ; ^b ; ^c ; ^{bruno.sarmento@ineb.up.pt" class="auth_mail" title="E-mail the corresponding author}

关键词：AIDS ; Acquired immune deficiency syndrome ; BLT ; Bone marrow/liver/thymus ; CC50 ; Half-maximal cytotoxic concentration ; DC-SIGN ; Dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin ; DCs ; Dendritic cells ; HIV ; Human immunodeficiency virus ; HSV ; Herpes simplex virus ; IC50 ; Half-maximal inhibitory concentration ; LCs ; Langerhans cells ; NNRTI ; Non-nucleoside reverse transcriptase inhibitor ; NPs ; Nanoparticles ; PAMAM ; Polyamidoamine ; PBMCs ; Peripheral blood mononuclear cells

刊名：Advanced Drug Delivery Reviews

出版年：2016

8.iRGD peptide conjugation potentiates intraperitoneal tumor delivery of paclitaxel with polymersomes

作者：Lorena Simó ; n-Gracia^a ; ^{Lorena.Simon.Gracia@ut.ee" class="auth_mail" title="E-mail the corresponding author} ; Hedi Hunt^a ; Pablo Scodeller^a ; ^b ; Jens Gaitzsch^c ; ^d ; Venkata Ramana Kotamraju^b ; Kazuki N. Sugahara^b ; ^e ; Olav Tammik^f ; Erkki Ruoslahti^b ; ^g ; Giuseppe Battaglia^c ; Tambet Teesalu^a ; ^b ; ^g ; ^{tteesalu@sbpdiscovery.org" class="auth_mail" title="E-mail the corresponding author}

关键词：Polymersomes ; Tumor penetrating peptides ; Peritoneal carcinomatosis ; Paclitaxel ; iRGD ; NRP-1

刊名：Biomaterials

出版年：2016

9.Double-targeted polymersomes and liposomes for multiple barrier crossing

作者：M. Sá ; nchez-Purrà ; ^a ; ^b ; V. Ramos^a ; V.A. Petrenko^c ; V.P. Torchilin^b ; S. Borró ; s^a ; ^d ; ^{salvador.borros@iqs.url.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：3B ; polymersomes from amphiphilic triblock copolymers ; DMPG ; phage fusion coat protein pVIII bearing DMPGTVLP ; CHOL ; methacryloylated cholesterol derivative ; REG ; regulon peptide ; PMOXA-PDMS-PMOXA ; poly(2-methyloxazoline)-b-poly(dimethylsiloxane)-b-poly(2-methyloxazoline)

刊名：International Journal of Pharmaceutics

出版年：2016

10.Antibody-drug conjugates for cancer therapy

作者：Anish Thomas ; MD^a ; Beverly A Teicher ; PhD^b ; Dr Raffit Hassan ; MD^a ; ^{hassanr@mail.nih.gov" class="auth_mail" title="E-mail the corresponding author}

刊名：The Lancet Oncology

出版年：2016

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