设为首页
收藏本站
网站地图
|
English
|
公务邮箱
About the library
Background
History
Leadership
Organization
Readers' Guide
Opening Hours
Collections
Help Via Email
Publications
Electronic Information Resources
常用资源
电子图书
期刊论文
学位会议
外文资源
特色专题
内部出版物
Wiley电子期刊(6)
SpringerLink电子期刊(151)
Elsevier电子期刊(403)
Springer电子图书(1)
NATURE电子期刊(13)
ACS电子期刊(85)
在“
Elsevier电子期刊
”中,
命中:
403
条,耗时:0.0209948 秒
在所有数据库中总计命中:
659
条
1.
Molecular docking, discovery, synthesis, and pharmacological properties of new 6-substituted-2-(3-phenoxyphenyl)-4-phenyl quinoline derivatives; an approach to developing potent
DNA
gyrase
inhibitors/antibacterial agents
作者:
Manikandan Alagumuthu
;
Sivakumar Arumugam
;
mailtomicromani@gmail.com
关键词:
Phenoxyphenyl quinolines
;
Antibacterial
;
DNA
gyrase
A
;
Molecular docking
;
Drug discovery
刊名:Bioorganic & Medicinal Chemistry
出版年:2017
2.
Linker-switch approach towards new ATP binding site inhibitors of
DNA
gyrase
B
作者:
Marko Jukič
a
;
Janez Ila&scaron
;
a
;
Matjaž Brvar
b
;
Danijel Kikelj
a
;
Jožko Cesar
a
;
Marko Anderluh
a
;
marko.anderluh@ffa.uni-lj.si
关键词:
Antibiotics
;
Antibacterials
;
Inhibitor
;
DNA
gyrase
B
;
ATP binding site
;
Pyrrole-2-carboxamides
;
Structure-based drug design
;
Ligand-based drug design
刊名:European Journal of Medicinal Chemistry
出版年:2017
3.
Design, synthesis and biological evaluation of 4,5-dibromo-N-(thiazol-2-yl)-1H-pyrrole-2-carboxamide derivatives as novel
DNA
gyrase
inhibitors
作者:
Tihomir Toma&scaron
;
ič
a
;
tihomir.tomasic@ffa.uni-lj.si
;
Matic Mirt
a
;
Michaela Barančoková
;
a
;
Janez Ila&scaron
;
a
;
Nace Zidar
a
;
Pä
;
ivi Tammela
b
;
Danijel Kikelj
a
关键词:
Antibacterial
;
DNA
gyrase
;
Docking
;
Inhibitor
;
Thiazole
刊名:Bioorganic & Medicinal Chemistry
出版年:2017
4.
Synthesis, crystal structure analysis, spectral (NMR, FT-IR, FT-Raman and UV-Vis) investigations, molecular docking studies, antimicrobial studies and quantum chemical calculations of a novel 4-chloro-8-methoxyquinoline-2(1H)-one: An effective antimicrobial agent and an inhibition of
DNA
gyrase
and lanosterol-14α-demethylase enzymes
作者:
S. Murugavel
a
;
smurugavel27@gmail.com
;
S. Sundramoorthy
b
;
D. Lakshmanan
c
;
R. Subashini
d
;
P. Pavan Kumar
e
关键词:
4-chloro-8-methoxyquinoline-2(1H)-one
;
XRD
;
Spectral
;
DFT
;
Antimicrobial activity
;
Molecular docking
刊名:Journal of Molecular Structure
出版年:2017
5.
Analysis of mutations in
DNA
gyrase
and topoisomerase IV of Ureaplasma urealyticum and Ureaplasma parvum serovars resistant to fluoroquinolones
作者:
Giorgio Piccinelli
;
Franco Gargiulo
;
Valeria Biscaro
;
Francesca Caccuri
;
Arnaldo Caruso
;
Maria Antonia De Francesco
;
maria.defrancesco@unibs.it
关键词:
Antibiotic resistance
;
QRDR
;
Serovars
刊名:Infection, Genetics and Evolution
出版年:2017
6.
Antimicrobial activity of novel 4H-4-oxoquinolizine compounds against extensively drug-resistant Acinetobacter baumannii strains
作者:
Seok Hyeon Na
a
;
Hyejin Jeon
a
;
Yoo Jeong Kim
a
;
Hyo Il Kwon
a
;
Gati Noble Selasi
a
;
Asiimwe Nicholas
a
;
Chang-Soo Yun
b
;
Sang Ho Lee
b
;
Je Chul Lee
a
;
leejc@knu.ac.kr
关键词:
4H-4-oxoquinolizine
;
Fluoroquinolone
;
Antimicrobial resistance
;
DNA
gyrase
inhibitor
;
Chemical compound
刊名:International Journal of Antimicrobial Agents
出版年:2017
7.
3,4-Dihydropyrimidinone-coumarin analogues as a new class of selective agent against S. aureus: Synthesis, biological evaluation and molecular modelling study
作者:
Nirmala S. Naik
a
;
Lokesh A. Shastri
a
;
drlashastri@kud.ac.in
;
Shrinivas D. Joshi
b
;
Sheshagiri R. Dixit
b
;
Bahubali M. Chougala
a
;
S. Samundeeswari
a
;
Megharaj Holiyachi
a
;
Farzanabi Shaikh
a
;
Jyoti Madar
a
;
Rashmi Kulkarni
a
;
Vinay Sunagar
c
关键词:
Coumarin
;
Matrix metalloproteinases
;
S. aureus
;
DNA
gyrase
;
Gelatin zymography
刊名:Bioorganic & Medicinal Chemistry
出版年:2017
8.
Ambient UV-B exposure reduces the binding of ofloxacin with bacterial
DNA
gyrase
and induces DNA damage mediated apoptosis
作者:
Jyoti Singh
a
;
e
;
1
;
Ashish Dwivedi
a
;
b
;
1
;
Syed Faiz Mujtaba
a
;
Krishna P. Singh
d
;
Manish Kumar Pal
c
;
Deepti Chopra
a
;
Shruti Goyal
a
;
e
;
Ajeet K. Srivastav
a
;
Divya Dubey
a
;
Shailendra K. Gupta
d
;
f
;
Chandana Haldar
b
;
Ratan Singh Ray
a
;
e
;
rsray@iitr.res.in" class="auth_mail" title="E-mail the corresponding author
;
ratanray.2001@rediffmail.com" class="auth_mail" title="E-mail the corresponding author
关键词:
OFLX
;
UV-B
;
DNA
gyrase
;
DNA
damage
;
Apoptosis
刊名:International Journal of Biochemistry and Cell Biology
出版年:2016
9.
Synthesis and biological evaluation of naphthoquinone-coumarin conjugates as topoisomerase II inhibitors
作者:
Idaira Hueso-Falcó
;
n
a
;
Á
;
ngel Amesty
a
;
1
;
Laura Anaissi-Afonso
b
;
1
;
Isabel Lorenzo-Castrillejo
b
;
Fé
;
lix Machí
;
n
b
;
fmachin@funcanis.org
;
Ana Esté
;
vez-Braun
a
;
aestebra@ull.es
关键词:
2-Hydroxynaphthoquinone
;
4-Hydroxycoumarin
;
Privileged structures
;
Topoisomerase II
;
ATPase
;
Docking
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2017
10.
Emergence of fluoroquinolone-resistant Propionibacterium acnes caused by amino acid substitutions of
DNA
gyrase
but not DNA topoisomerase IV
作者:
Keisuke Nakase
;
Yui Sakuma
;
Hidemasa Nakaminami
;
Norihisa Noguchi
;
noguchin@toyaku.ac.jp
关键词:
Propionibacterium acnes
;
Fluoroquinolone resistance
;
DNA
gyrase
;
Amino acid substitution
刊名:Anaerobe
出版年:2016
1
2
3
4
5
6
7
8
9
按检索点细分(403)
题名(123)
关键词(130)
文摘(329)
按出版年细分(403)
2027年及以后(11)
2017年(9)
2016年(24)
2015年(10)
2013年(26)
2012年(23)
2011年(21)
2010年(21)
2009年(16)
2008年(14)
2007年(20)
2006年(19)
2005年(20)
2004年(16)
2003年(8)
2002年(14)
2001年(15)
2000年(13)
2000年及以前(103)
NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via
email
.