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内部出版物
SpringerLink电子期刊(51)
NATURE电子期刊(9)
Elsevier电子期刊(283)
ACS电子期刊(12)
在“
Elsevier电子期刊
”中,
命中:
283
条,耗时:0.0569405 秒
在所有数据库中总计命中:
355
条
1.
DNA
-PKcs: A promising therapeutic target in human hepatocellular carcinoma?
作者:
Rosa M. Pascale
a
;
1
;
Christy Joseph
b
;
1
;
Gavinella Latte
a
;
Matthias Evert
c
;
Francesco Feo
a
;
Diego F. Calvisi
a
;
b
;
calvisid@uniss.it" class="auth_mail" title="E-mail the corresponding author
关键词:
CHIP
;
chromatin immunoprecipitation
;
DNA
-PKcs
;
DNA
dependent
protein
kinase
catalytic
subunit
;
DSBs
;
double strand breaks
;
GI
;
genomic instability
;
HCC
;
hepatocellular carcinoma
;
NHEJ
;
non-homologous end-joining
刊名:
DNA
Repair
出版年:2016
2.
Lovastatin prevents cisplatin-induced activation of pro-apoptotic
DNA
damage response (DDR) of renal tubular epithelial cells
作者:
Katharina Krü
;
ger
a
;
Verena Ziegler
a
;
Christina Hartmann
a
;
Christian Henninger
a
;
Jü
;
rgen Thomale
b
;
Nicole Schupp
a
;
Gerhard Fritz
a
;
fritz@uni-duesseldorf.de" class="auth_mail" title="E-mail the corresponding author
关键词:
ApG
;
adenine-guanine
;
ATM
;
ataxia telangiectasia mutated
;
ATR
;
ataxia telangiectasia and Rad3 related
kinase
;
Bax
;
Bcl2-associated X
protein
;
Bcl2
;
B-cell/lymphoma 2
;
Chk1
;
checkpoint
kinase
1
;
Chk2
;
checkpoint
kinase
2
;
CisPt
;
cisplatin
;
Ctr1
;
solute carrier family 31 (copper transporter)
;
member 1 (SLC31A1)
;
Csb
;
Cockayne syndrome group B
;
DAPI
;
4&prime
;
6-diamidino-2-phenylindole
;
DDR
;
DNA
damage response
;
DSBs
;
DNA
double-strand breaks
;
DNA
-PKcs
;
catalytic
subunit
of the
DNA
-
dependent
protei
刊名:Toxicology and Applied Pharmacology
出版年:2016
3.
A novel small molecule inhibitor of the
DNA
repair
protein
Ku70/80
作者:
Eric Weterings
a
;
1
;
eweterings@email.arizona.edu" class="auth_mail" title="E-mail the corresponding author
;
Alfred C. Gallegos
a
;
Lauren N. Dominick
a
;
Laurence S. Cooke
b
;
Trace N. Bartels
a
;
Josef Vagner
c
;
Terry O. Matsunaga
d
;
Daruka Mahadevan
b
;
1
关键词:
DNA
-PKCS
;
DNA
-
dependent
protein
kinase
catalytic
subunit
;
DSB
DNA
;
double strand break
;
EMSA
;
electrophoretic mobility shift assay
;
GBM
;
glioblastoma multiforme
;
NHEJ
;
non-homologous end-joining
;
PrEC
;
prostate epithelial cells
;
RT
;
radiation therapy
刊名:
DNA
Repair
出版年:2016
4.
Lovastatin protects keratinocytes from
DNA
damage-related pro-apoptotic stress responses stimulated by anticancer therapeutics
作者:
Verena Ziegler
1
;
Anne Albers
1
;
Gerhard Fritz
;
fritz@uni-duesseldorf.de" class="auth_mail" title="E-mail the corresponding author
关键词:
53BP1
;
tumor suppressor p53 binding
protein
1
;
ATM
;
ataxia telangiectasia mutated
;
ATR
;
ataxia telangiectasia and Rad3-related
;
Chk
;
checkpoint
kinase
;
DSB
;
DNA
double-strand break
;
DDR
;
DNA
damage response
;
DNA
-PKcs
;
DNA
-
dependent
protein
kinase
;
catalytic
subunit
;
Doxo
;
doxorubicin
;
5-FU
;
5-fluorouracil
;
γH2AX
;
Ser139 phosphorylated histone H2AX
;
HU
;
hydroxyurea
;
IR
;
ionizing radiation
;
JNK
;
c-Jun N-terminal
kinase
;
Kap1
;
KRAB-associated
protein
1
;
Lova
;
HMG-CoA-reductase inhibitor lovastatin
刊名:Biochimica et Biophysica Acta (BBA)-Molecular Cell Research
出版年:2016
5.
T0070907 inhibits repair of radiation-induced
DNA
damage by targeting RAD51
作者:
Zhengzhe An
a
;
Jae-Ran Yu
b
;
Woo-Yoon Park
a
;
wynpark@chungbuk.ac.kr" class="auth_mail" title="E-mail the corresponding author
关键词:
DNA
-PK
;
DNA
-
dependent
protein
kinase
;
DNA
-PKcs
;
DNA
-
dependent
protein
kinase
catalytic
subunit
;
DSB
;
double-strand break
;
FBS
;
foetal bovine serum
;
HR
;
homologous recombination
;
IR
;
ionising radiation
;
NHEJ
;
non-homologous end joining
;
PPARγ
;
peroxisome proliferator-activated receptor gamma
;
RT
;
radiation therapy
;
T007
;
T0070907
;
TBST
;
Tris-buffered saline and Tween 20
刊名:Toxicology in Vitro
出版年:2016
6.
Synergistic potentiation of (−)-lomaiviticin A cytotoxicity by the ATR inhibitor VE-821
作者:
Laureen C. Colis
a
;
Seth B. Herzon
a
;
b
;
seth.herzon@yale.edu" class="auth_mail" title="E-mail the corresponding author
关键词:
ATR
;
ataxia telangiectasia and Rad3-related
protein
;
SSB
;
single-strand break
;
DSB
;
double-strand break
;
PI3KK
;
phosphatidylinositol 3-
kinase
-related
kinase
;
ATM
;
ataxia telangiectasia mutated
;
DNA
-PKcs
;
DNA
-
dependent
protein
kinase
catalytic
subunit
;
BRCA2
;
breast cancer type 2
;
PTEN
;
phosphatase and tensin homolog
;
KU80
;
Ku autoantigen
protein
p80
;
NHEJ
;
non-homologous end joining
;
HR
;
homologous recombination
;
IR
;
ionizing radiation
;
PARP-1
;
poly(ADP-ribose) polymerase-1
;
PARP-2
;
poly(ADP-rib
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2016
7.
The role of gene mutations and gene products in intestinal tissue reactions from ionising radiation
作者:
Jolyon H. Hendry
a
;
jhendry2002uk@yahoo.com
;
Kensuke Otsuka
b
关键词:
Ascl2
;
achaete-scute family bHLH transcription factor 2
;
ASM
;
ase acid sphingomyelinase
;
ATM
;
ataxia telangiectasia mutated
;
Bak1
;
Bcl2 antagonist/killer 1
;
Bax
;
Bcl2 associated X
;
Bcl-2
;
B-cell lymphoma 2
;
bFGF
;
basic fibroblast growth factor
;
Bmi1
;
B lymphoma Mo-MLV insertion region 1 homolog
;
BMP
;
bone morphogenetic
protein
;
BMT
;
bone marrow transplants
;
CBC
;
crypt base columnar
;
DLL1
;
delta-like 1
;
DNA
-PKcs
;
DNA
-
dependent
protein
kinase
catalytic
subunit
;
EGF
;
epidermal growth factor
;
FGF
;
f
刊名:Mutation Research/Reviews in Mutation Research
出版年:2016
8.
Novel non-peptide small molecules preventing IKKβ/NEMO association inhibit NF-κB activation in LPS-stimulated J774 macrophages
作者:
Francesca De Falco
1
;
Carmen Di Giovanni
1
;
Carmen Cerchia
;
Daniela De Stefano
2
;
Antonella Capuozzo
;
Carlo Irace
;
Teresa Iuvone
;
Rita Santamaria
;
Rosa Carnuccio
;
rosa.carnuccio@unina.it" class="auth_mail" title="E-mail the corresponding author
;
Antonio Lavecchia
;
antonio.lavecchia@unina.it" class="auth_mail" title="E-mail the corresponding author
关键词:
ADME
;
absorption
;
distribution
;
metabolism
;
and excretion
;
DMEM
;
Dulbecco&rsquo
;
s modified Eagle&rsquo
;
s medium
;
DMSO
;
dimethyl sulfoxide
;
EMSA
;
Electrophoretic Mobility Shift Assay
;
Erk
;
extracellular-signal-related
kinase
;
FBS
;
foetal bovine serum
;
GAPDH
;
glyceraldehyde-3-phosphate dehydrogenase
;
Glide SP
;
Glide Single Precision
;
Glide XP
;
Glide extra precision
;
H-bonds
;
hydrogen bonds
;
HTVS
;
high-throughput virtual screening
;
IKK
;
IκB
kinase
;
iNOS
;
inducible nitric-oxide synthase
;
J774 macrop
刊名:Biochemical Pharmacology
出版年:2016
9.
Versatility in phospho-
dependent
molecular recognition of the XRCC1 and XRCC4
DNA
-damage scaffolds by aprataxin-family FHA domains
作者:
Amy L. Cherry
a
;
1
;
Timothy J. Nott
a
;
2
;
Geoffrey Kelly
b
;
Stuart L. Rulten
b
;
Keith W. Caldecott
b
;
Stephen J. Smerdon
a
;
Steve.Smerdon@crick.ac.uk" class="auth_mail" title="E-mail the corresponding author
关键词:
APLF
;
aprataxin- and PNK-like factor
;
PNKP
;
polynucleotide
kinase
phosphatase
;
FHA
;
forkhead-associated
;
XRCC1
;
X-ray repair cross-complementing
protein
1
;
XRCC4
;
X-ray repair cross-complementing
protein
4
;
PARP-1
;
poly(ADP-ribose)polymerase 1
;
NHEJ
;
non-homologous end-joining
;
DNA
-PKcs
;
catalytic
subunit
of
DNA
-
dependent
protein
kinase
;
CK2
;
casein
kinase
2
;
HIT
;
Histidine triad
;
ZF
;
zinc finger
;
NTD
;
N-terminal domain
;
BRCT
;
BRCA1 C-terminal
;
CC
;
coiled-coil
;
ITC
;
isothermal titration calorime
刊名:
DNA
Repair
出版年:2015
10.
ATR signaling cooperates with ATM in the mechanism of low dose hypersensitivity induced by carbon ion beam
作者:
Lian Xue
a
;
b
;
Yoshiya Furusawa
c
;
Dong Yu
d
;
yudong@suda.edu.com" class="auth_mail" title="E-mail the corresponding author
关键词:
IR
;
ionizing radiation
;
LET
;
linear energy transfer
;
HRS
;
hyper-radiosensitivity
;
IRR
;
induced radioresistance
;
DSB
;
DNA
double strand break
;
ATM
;
ataxia telangiectasia mutated homolog
;
ATR
;
ataxia telangiectasia and Rad3 related
;
DNA
-PKcs
;
DNA
-
dependent
protein
kinase
catalytic
subunit
;
CHK1
;
checkpoint
kinase
1
;
ss
DNA
;
single strand
DNA
;
RPA
;
replication
protein
A
;
NHEJ
;
non-homologous end-joining
;
HR
;
homologous recombination
刊名:
DNA
Repair
出版年:2015
1
2
3
4
5
6
7
8
9
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