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SpringerLink电子期刊(1)
Elsevier电子期刊(24)
ACS电子期刊(5)
在“
Elsevier电子期刊
”中,
命中:
24
条,耗时:小于0.01 秒
在所有数据库中总计命中:
30
条
1.
Analysis of boceprevir resistance associated amino acid variants (RAVs) in two phase 3 boceprevir clinical studies
作者:
Richard
J
.O. Barnard
;
J
ohn A. Howe
;
Robert A. Ogert
;
Stefan Zeuzem
;
Fred Poordad
;
Stuart C. Gordon
;
Robert Ralston
;
Xiao Tong
;
Vilma Sniukiene
;
J
ulie Strizki
;
Desmond Ryan
;
J
ianmin Long
;
Ping Qiu
;
Clifford A. Brass
;
J
anice Albrecht
;
Margaret Burroughs
;
Scott Vuocolo
;
Daria
J
.
Hazuda
关键词:
HCV
;
Boceprevir
;
Variants
;
RAV
;
Resistance
刊名:Virology
出版年:2013
2.
Emergence of resistance-associated variants after failed triple therapy with vaniprevir in treatment-experienced non-cirrhotic patients with hepatitis C-genotype 1 infection: A population and clonal analysis
作者:
Richard
J
.O. Barnard
;
Carolyn M. McHale
;
William Newhard
;
Carol A. Cheney
;
Donald
J
. Graham
;
Amy L. Himmelberger
;
J
ulie Strizki
;
Peggy M.T. Hwang
;
Amber A. Rivera
;
J
acqueline D. Reeves
;
David Nickle
;
Mark
J
. DiNubile
;
Daria
J
.
Hazuda
;
Niloufar Mobashery
关键词:
DAA
;
directly acting antiviral agent
;
HCV
;
hepatitis C virus
;
IC50
;
inhibitory concentration 50 %
;
IU/mL
;
international units per milliliter
;
LLD
;
lower limit of detection
;
LLQ
;
lower limit of quantification
;
P/R
;
peginterferon alfa/ribavirin
;
SVR
;
sustain
刊名:Virology
出版年:2013
3.
Raltegravir once daily or twice daily in previously untreated patients with HIV-1: a randomised, active-controlled, phase 3 non-inferiority trial
作者:
J
oseph J
;
Eron
J
r ProfMD
a
;
J
ü
;
rgen K
;
Rockstroh MD
b
;
J
acques
;
Reynes ProfMD
c
;
J
aime
;
Andrade-Villanueva MD
d
;
J
ose Valdez
;
Ramalho-Madruga MD
e
;
Linda-Gail
;
Bekker MD
f
;
Ben
j
amin
;
Young MD
g
;
Christine
;
Katlama MD
h
;
J
ose Maria
;
Gatell-Artigas MD
i
;
J
ose R
;
Arribas MD
j
;
Mark
;
Nelson MD
k
;
Havilland
;
Campbell BS
l
;
J
ing
;
Zhao PhD
l
;
Anthony
J
;
Rodgers MS
l
;
Matthew L
;
Rizk PhD
l
;
Larissa
;
Wenning PhD
l
;
Michael D
;
Miller PhD
l
;
Daria
;
Hazuda
PhD
l
;
Mark
J
;
DiNubile MD
l
;
Randi
;
Leavitt MD
l
;
Robin
;
Isaacs MD
l
;
Michael N
;
Robertson MD
l
;
Peter
;
Sklar MD
l
;
Bach-Yen
;
Nguyen DrMD
l
;
;
bachyen_nguyen@merck.com
;
for the QDMRK Investigators
刊名:The Lancet Infectious Diseases
出版年:2011
4.
Assessment of the susceptibility of mutant HIV-1 to antiviral agents
作者:
Ying-
J
ie Wang
;
Philip M. McKenna
;
Renee Hrin
;
Peter Felock
;
Meiqing Lu
;
Kristen G.
J
ones
;
Craig A. Coburn
;
J
ay A. Grobler
;
Daria
J
.
Hazuda
;
Michael D. Miller
;
Ming-Tain Lai
关键词:
Phenotypic assay
;
Resistance selection
;
HIV-1
;
Protease inhibitor
;
Susceptibility
刊名:
J
ournal of Virological Methods
出版年:2010
5.
Purification of untagged HIV-1 reverse transcriptase by affinity chromatography
作者:
Meiqing Lu
;
Winnie Ngo
;
Ye Mei
;
V
;
na Munshi
;
Christine Burlein
;
Marie H. Loughran
;
Peter D. Williams
;
Daria
J
.
Hazuda
;
Michael D. Miller
;
J
ay A. Grobler
;
Tracy L. Diamond
;
Ming-Tain Lai
关键词:
HIV-1
;
Reverse transcriptase
;
Affinity chromatography
;
RNase H
刊名:Protein Expression and Purification
出版年:2010
6.
Scintillation proximity assays for mechanistic and pharmacological analyses of HIV-1 integration
作者:
J
ay A. Grobler
;
Kara A. Stillmock
;
Daria
J
.
Hazuda
关键词:
HIV-1
;
AIDS
;
Integrase
;
Integration
;
Integrase strand transfer inhibitor (InSTI)
;
High-throughput
;
Scintillation proximity assay
;
Raltegravir
刊名:Methods
出版年:2009
7.
MK-5172, a Novel Macrocyclic Inhibitor of NS3/4a Protease Demonstrates Efficacy Against Viral Resistance in the Chimpanzee Model of Chronic Hepatitis C Virus Infection
作者:
Steve Ludmerer
1
;
;
Steve Carroll
2
;
J
ohn McCauley
3
;
Mike Rudd
3
;
Paul Coleman
3
;
Nigel Liverton
3
;
Christine Burlein
2
;
J
ill DiMuzio
2
;
Adam Gates
2
;
Don Graham
1
;
Carolyn McHale
1
;
Mark Stahlhut
2
;
Christine Fandozzi
4
;
Daria
Hazuda
2
;
J
oe Vacca
1
;
David Olsen
2
刊名:Antiviral Research
出版年:2010
8.
Design and synthesis of substituted 4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxamides, novel HIV-1 integrase inhibitors
作者:
H. Marie Langford
;
Peter D. Williams
;
Carl F. Homnick
;
J
oseph P. Vacca
;
Peter
J
. Felock
;
Kara A. Stillmock
;
Marc V. Witmer
;
Daria
J
.
Hazuda
;
Lori
J
. Gabryelski
;
William A. Schleif
关键词:
HIV-1
;
Integrase inhibitor
;
Antiviral
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2008
9.
Synthesis of 5-(1-H or 1-alkyl-5-oxopyrrolidin-3-yl)-8-hydroxy-[1,6]-naphthyridine-7-carboxamide inhibitors of HIV-1 integrase
作者:
J
effrey Y. Melamed
;
Melissa S. Egbertson
;
S
;
or Varga
;
J
oseph P. Vacca
;
Greg Moyer
;
Lori Gabryelski
;
Peter
J
. Felock
;
Kara A. Stillmock
;
Marc V. Witmer
;
William Schleif
;
Daria
J
.
Hazuda
;
Yvonne Leonard
关键词:
HIV
;
Integrase
;
Antiviral
;
Pyrrolidinone synthesis
;
Butenolide
;
1
;
6-Naphthyridine
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2008
10.
Monitoring the development of non-nucleoside reverse transcriptase inhibitor-associated resistant HIV-1 using an electrochemiluminescence-based reverse transcriptase polymerase assay
作者:V ;
na Munshi
;
Meiqing Lu
;
Peter Felock
;
Richard
J
.O. Barnard
;
Daria
J
.
Hazuda
;
Michael D. Miller
;
Ming-Tain Lai
关键词:
ECL-based assay
;
RT polymerase assay
;
HIV-1
;
Resistance mutation
;
NNRTI
刊名:Analytical Biochemistry
出版年:2008
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