搜索页_+Double+APP+transgenic+mouse

设为首页

收藏本站

网站地图 | English | 公务邮箱

About the library

Background
History
Leadership
Organization

Readers' Guide

Opening Hours
Collections
Help Via Email

Publications

Electronic Information Resources

外文资源

Elsevier电子期刊(377)

在“Elsevier电子期刊”中，命中：377条，耗时：0.0380115 秒

在所有数据库中总计命中：434条

1.Potential role of IL-17-producing CD4/CD8 double negative αβ T cells in psoriatic skin inflammation in a TPA-induced STAT3C transgenic mouse model

作者：Azumi Ueyama^a ; ^{azumi.ueyama@shionogi.co.jp} ; Chihiro Imura^a ; Yasuyuki Fusamae^a ; Kenichiro Tsujii^a ; Yoko Furue^b ; Miwa Aoki^a ; Minoru Suzuki^a ; Tomohiko Okuda^a ; Itsuki Oshima^a ; Kiyoshi Yasui^c ; Michitaka Shichijo^a ; Mina Yamamoto^a

关键词：ILC ; innate lymphoid cells ; MAIT cell ; mucosal associated invariant T cell ; IMQ ; imiquimod ; TLR7 ; Toll-like receptor ; TPA ; tumor promoter 12-O-tetradecanoylphorbol-13-acetate ; DN αβ T cells ; αβ-TCR+ CD4CD8 double negative T cells ; RORγt ; retinoic acid-related orphan receptor gamma t ; CCR6 ; CC chemokine receptor 6 ; SLE ; systematic lupus erythematosus ; ALPS ; autoimmune lymphoproliferative syndrome ; PMA ; phorbol 12-myristate 13-acetate ; LN ; lymph node ; NK T cell ; natural killer T cell ; DC ; dendriti

刊名：Journal of Dermatological Science

出版年：2017

2.Magnetic resonance T2 relaxation time at 7 Tesla associated with amyloid β pathology and age in a double-transgenic mouse model of Alzheimer’s disease

作者：Lang Li^a ; Xiao-Yi Wang^a ; ^b ; Fa-Bao Gao^c ; ^d ; Lei Wang^c ; ^d ; Rui Xia^c ; ^d ; Zhi-Xiao Li^a ; Wu Xing^a ; Bei-Sha Tang^e ; Yi Zeng^f ; Gao-Feng Zhou^a ; Hai-Yan Zhou^g ; Wei-Hua Liao^a ; ^b ; ^{ouwenliao@163.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Alzheimer&rsquos ; disease ; Double transgenic mice ; Amyloid-β ; MRI ; Immunohistochemistry

刊名：Neuroscience Letters

出版年：2016

3.Generation of a double transgenic humanized neonatal Fc receptor (FcRn)/albumin mouse to study the pharmacokinetics of albumin-linked drugs

作者：Dorthe Viuff^a ; Filipa Antunes^b ; Leslie Evans^b ; Jason Cameron^b ; Hans Dyrnesli^c ; Birgitte Thue Ravn^a ; Magnus Stougaard^d ; Kader Thiam^e ; Birgitte Andersen^a ; Sø ; ren Kjæ ; rulff^a ; Kenneth A. Howard^c ;

关键词：Albumin ; Drug delivery ; Neonatal Fc receptor ; Protein engineering ; Animal model ; Drug development

刊名：Journal of Controlled Release

出版年：2016

4.Hippocampal neurogenesis in the APP/PS1/nestin-GFP triple transgenic mouse model of Alzheimer’s disease

作者：Q. Zeng^a ; M. Zheng^b ; T. Zhang^a ; G. He^a ; ^c ; ^{guiqionghe@hotmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：2xTgAD ; APP/PS1 double transgenic mice ; 3xTgAD ; APP/PS1/nestin-GFP triple transgenic mice ; Aβ ; amyloid-β ; AD ; Alzheimer&rsquo ; s disease ; ANOVA ; analysis of variance ; APP ; amyloid precursor protein ; BrdU ; 5-bromo-2-deoxyuridine ; DCX ; doublecortin ; DG ; dentate gyrus ; LVs ; lateral ventricles ; NPCs ; neural progenitors ; NSCs ; neural stem cells ; PBS ; phosphate-buffered saline ; PS1 ; presenilin-1 ; SEM ; standard error of the mean ; SGZ ; subgranular zone ; SVZ ; subventricular zone ; WT ; wild-type littermates

刊名：Neuroscience

出版年：2016

5.A comparative evaluation of treatments with 17β-estradiol and its brain-selective prodrug in a double-transgenic mouse model of Alzheimer's disease

作者：Anna E. Tschiffely^a ; ^b ; ¹ ; Rosemary A. Schuh^c ; ^d ; Katalin Prokai-Tatrai^e ; ^f ; Laszlo Prokai^e ; ^f ; ² ; ^{Laszlo.Prokai@unthsc.edu" class="auth_mail" title="E-mail the corresponding author} ; Mary Ann Ottinger^b ; ² ; ³ ; ^{maotting@central.uh.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Estradiol ; Brain-selective prodrug ; Alzheimer's disease ; Transgenic mice ; Amyloid-β ; Radial arm water maze

刊名：Hormones and Behavior

出版年：2016

6.The double-edge role of B cells in mediating antitumor T-cell immunity: Pharmacological strategies for cancer immunotherapy

作者：Jing-Zhang Wang^a ; ^{wangjingzhang1981@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; ^{jingzhangwang@hebeu.edu.cn" class="auth_mail" title="E-mail the corresponding author} ; Yu-Hua Zhang^b ; Xin-Hua Guo^c ; Hong-Yan Zhang^a ; Yuan Zhang^a

关键词：DC ; dendritic cell ; NK ; natural killer cell ; BCR ; B-cell receptor ; TNF ; tumor necrosis factor ; MHC ; major histocompatibility complex ; LMP ; liver-metastatic pancreatic ; FcγR ; Fc gamma receptor ; TRAMP ; the transgenic adenocarcinoma of the mouse prostate model ; TGFβ ; transforming growth factor β ; TGFβR2 ; TGFβ receptor type 2 ; IL-10 ; interleukin-10 ; IL-10R1 ; the transmembrane receptor of IL-10 ; Tregs ; regulatory T cells ; Bregs ; regulatory B cells ; PD-1 ; programmed death-1 ; PD-L1 ; the programmed deat

刊名：International Immunopharmacology

出版年：2016

7.Efficacy and safety of tau-aggregation inhibitor therapy in patients with mild or moderate Alzheimer's disease: a randomised, controlled, double-blind, parallel-arm, phase 3 trial

作者：Prof Serge Gauthier ; MD^a ; Prof Howard H Feldman ; MD^b ; Prof Lon S Schneider ; MD^c ; Prof Gordon K Wilcock ; DM^d ; Prof Giovanni B Frisoni ; MD^e ; Jiri H Hardlund ; MD^f ; Hans J Moebius ; MD^g ; Peter Bentham ; MBChB^f ; Karin A Kook ; PhD^h ; Damon J Wischik ; PhD^f ; Prof Bjoern O Schelterⁱ ; Charles S Davis ; PhD^l ; Roger T Staff ; PhD^m ; Luc Bracoud ; MScⁿ ; Kohkan Shamsi ; MD^o ; Prof John M D Storey^j ; Charles R Harrington ; PhD^k ; Prof Claude M Wischik ; MBBS^f ; ^k ; ^{cmw@taurx.com}

刊名：The Lancet

出版年：2016

8.The Ames dwarf mutation attenuates Alzheimer's disease phenotype of APP/PS1 mice

作者：Kendra L. Puig^a ; Joshua A. Kulas^a ; Whitney Franklin^b ; ^c ; Sharlene G. Rakoczy^a ; Giulio Taglialatela^c ; Holly M. Brown-Borg^a ; Colin K. Combs^a ; ^{colin.combs@med.und.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：Neuroinflammation ; Cytokine ; Growth hormone ; Aging ; Dwarf ; Alzheimer ; IGF-1 ; Amyloid

刊名：Neurobiology of Aging

出版年：2016

9.Cardiac remodeling in Gα_q and Gα₁₁ knockout mice

作者：Kathrina Wiesen^a ; ^b ; Elisabeth Kaiser^b ; Laura Schrö ; der^b ; Anke Scholz^b ; Sandra Ruppenthal^b ; Jan-Christian Reil^c ; Christina Backes^d ; Eckart Meese^d ; Carola Meier^e ; Anna Bogdanova^a ; Peter Lipp^b ; ¹ ; ^{peter.lipp@uks.eu" class="auth_mail" title="E-mail the corresponding author} ; Lars Kaestner^b ; ¹ ; ^{lars_kaestner@me.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Gαq/Gα11-signaling ; Cardiac tissue-remodeling ; Matricellular proteins ; Cyr61

刊名：International Journal of Cardiology

出版年：2016

10.Activation of Slit2-Robo1 signaling promotes liver fibrosis

作者：Jianlan Chang² ; ⁵ ; ^&dagger ; ; Tian Lan¹ ; ^&dagger ; ; Changzheng Li¹ ; Xiaoqian Ji¹ ; Lingyun Zheng¹ ; Hongju Gou² ; Yitao Ou¹ ; Teng Wu¹ ; Cuiling Qi¹ ; Qianqian Zhang¹ ; Jiangchao Li¹ ; Quliang Gu¹ ; Dingwen Wen¹ ; Liu Cao⁴ ; Liang Qiao³ ; ^{liang.qiao@sydney.edu.au" class="auth_mail" title="E-mail the corresponding author} ; Yanqing Ding² ; ^{dyq@fimmu.com" class="auth_mail" title="E-mail the corresponding author} ; Lijing Wang¹ ; ^{wanglijing62@163.com" class="auth_mail" title="E-mail the corresponding author}

关键词：α-SMA ; α-smooth muscle actin ; CCl4 ; carbon tetrachloride ; ECM ; extracellular matrix ; HSCs ; hepatic stellate cells ; Robo1/2+/&minus ; mice ; Robo1+/&minus ; Robo2+/&minus ; double heterozygotes mice ; Slit2-Tg mice ; Slit2-transgenic mice ; TGF-β1 ; transforming growth factor-β

刊名：Journal of Hepatology

出版年：2015

按检索点细分(377)

题名(31)

关键词(10)

文摘(253)

按出版年细分(377)

2027年及以后(10)

2017年(1)

2016年(8)

2015年(4)

2013年(18)

2012年(24)

2011年(27)

2010年(27)

2009年(36)

2008年(25)

2007年(23)

2006年(21)

2005年(16)

2004年(23)

2003年(14)

2002年(23)

2001年(21)

2000年(17)

2000年及以前(39)