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内部出版物
Elsevier电子期刊(3)
在“
Elsevier电子期刊
”中,
命中:
3
条,耗时:小于0.01 秒
在所有数据库中总计命中:
3
条
1.
Macrocyclic MEK1/2 inhibitor with efficacy in a mouse model of cardiomyopathy caused by lamin A/C gene mutation
作者:
Wei Wu
a
;
b
;
Mahendra D. Chordia
c
;
g
;
Barry P. Hart
d
;
E.
Sathyajith
Kumarasinghe
c
;
Min K. Ji
c
;
Ajay Bhargava
e
;
Michael W. Lawlor
f
;
Ji-Yeon Shin
a
;
b
;
Fusako Sera
a
;
Shunichi Homma
a
;
Antoine Muchir
a
;
b
;
h
;
Uday R. Khire
c
;
d
;
ukhire@allomek.com
;
Howard J. Worman
a
;
b
;
hjw14@columbia.edu
关键词:
Cardiomyopathy
;
Emery-Dreifuss muscular dystrophy
;
Extracellular signal-regulated kinase
;
Lamin
;
MEK inhibitor
;
Mitogen-activated protein kinase
刊名:Bioorganic & Medicinal Chemistry
出版年:2017
2.
The discovery of reverse tricyclic pyridone JAK2 inhibitors. Part 2: Lead optimization
作者:
Tony Siu
a
;
tony_siu@merck.com" class="auth_mail
;
Sathyajith
E.
Kumarasinghe
a
;
Michael D. Altman
b
;
Matthew Katcher
a
;
Alan Northrup
a
;
Catherine White
a
;
Craig Rosenstein
c
;
Anjili Mathur
d
;
Lin Xu
e
;
Grace Chan
c
;
Eric Bachman
d
;
Melaney Bouthillette
f
;
Christopher J. Dinsmore
a
;
C. Gary Marshall
g
;
Jonathan R. Young
a
关键词:
JAK2
;
Kinases
;
Water interaction
;
Kinase selectivity
;
Ligand binding affinity
;
Kinase partition index
;
Molecular modeling
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:15 March, 2014
3.
Synthesis of 5,6-bis(alkyn-1-yl)pyrimidines and related nucleosides
作者:
Kumarasinghe
;
E.
Sathyajith
;
Peterson
;
Matt A.
;
Robins*
;
Morris J.
刊名:Tetrahedron Letters
出版年:2000
1
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