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Elsevier电子期刊(12)

在“Elsevier电子期刊”中，命中：12条，耗时：小于0.01 秒

在所有数据库中总计命中：12条

1.Novel antibody drug conjugates containing exatecan derivative-based cytotoxic payloads

作者：Takashi Nakada ; ^{nakada.takashi.g6@daiichisankyo.co.jp" class="auth_mail" title="E-mail the corresponding author} ; Takeshi Masuda ; Hiroyuki Naito ; Masao Yoshida ; Shinji Ashida ; Koji Morita ; Hideki Miyazaki ; Yuji Kasuya ; Yusuke Ogitani ; Junko Yamaguchi ; Yuki Abe ; Takeshi Honda

关键词：Antibody drug conjugate ; Camptothecin ; Exatecan ; Cytotoxic payload ; Linker ; Anti-HER2 ; Trastuzumab ; Oncology ; Cancer therapy

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

2.Wide application of a novel topoisomerase I inhibitor-based drug conjugation technology

作者：Yusuke Ogitani ; Yuki Abe ; Takuma Iguchi ; Junko Yamaguchi ; Tomoko Terauchi ; Michiko Kitamura ; Koichi Goto ; Mayumi Goto ; Masataka Oitate ; Hideo Yukinaga ; Yoshiyuki Yabe ; Takashi Nakada ; Takeshi Masuda ; Koji Morita ; Toshinori Agatsuma

关键词：Drug-delivery system ; Antibody&ndash ; drug conjugate ; Topoisomerase I inhibitor ; Exatecan ; Membrane permeability ; B7-H3 ; Oncology ; Cancer therapy

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2016

3.Exatecan in pretreated adult patients with advanced soft tissue sarcoma: Results of a phase II – Study of the EORTC Soft Tissue and Bone Sarcoma Group

作者：P. Reichardt ; O.S. Nielsen ; S. Bauer ; J.T. Hartmann ; P. Schö ; ffski ; T.B. Christensen ; D. Pink ; S. Daugaard ; S. Marreaud ; M. Van Glabbeke ; et al.

关键词：Soft tissue sarcoma ; Topoisomerase I-inhibitors ; Exatecan

刊名：European Journal of Cancer

出版年：2007

4.Phase II study of exatecan mesylate (DX-8951f) as first line therapy for advanced non-small cell lung cancer

作者：Braybrooke ; J.P. ; Ranson ; M. ; Manegold ; C. ; Mattson ; K. ; Thatcher ; N. ; Cheverton ; P. ; Sekiguchi ; M. ; et. al.

关键词：Exatecan ; Non-small cell lung cancer ; Topoisomerase I ; DX-8951f ; Phase II

刊名：Lung Cancer

出版年：2003

5.A phase IIA study of the topoisomerase I inhibitor, exatecan mesylate (DX-8951f), administered at two different dose schedules in patients with platinum- and taxane-resistant/refractory ovarian cancer

作者：Clamp ; A. ; Adams ; M. ; Atkinson ; R. ; Boven ; E. ; Calvert ; A.H. ; Cervantes ; A ; Ganesan ; T. ; Lotz ; J. ; et. al.

关键词：Ovarian cancer ; Exatecan mesylate ; Topoisomerase I ; Clinical trial

刊名：Gynecologic Oncology

出版年：2004

6.Recent developments in the clinical activity of topoisomerase-1 inhibitors

作者：Karen J. Haglof ; Elizabeta Popa ; Howard S. Hochster

关键词：Topoisomerase-1 ; Topoisomerase-1 inhibitor(s) ; Cleavable complex ; Topotecan ; Irinotecan ; 9-Amino-camptothecin ; 9-Nitro-camptothecin ; Exatecan ; Lurtotecan ; Edotecarin ; Camptothecin(s)

刊名：Update on Cancer Therapeutics

出版年：2006

7.Exatecan and gemcitabine: no better than gemcitabine only

作者：Olwen Glynn Owen

刊名：Lancet Oncology

出版年：2006

8.Topoisomerase I Inhibitors in the Treatment of Gastrointestinal Cancer: From Intravenous to Oral Administration

作者：Isa E.L.M. Kuppens^a ; ^{i.kuppens@nki.nl} ; Jos H. Beijnen^a ; ^b ; ^c ; Jan H.M. Schellens^a ; ^c

关键词：Colorectal cancer ; Esophageal cancer ; Gastric cancer ; Pancreatic cancer

刊名：Clinical Colorectal Cancer

出版年：2004

9.Liquid chromatographic assays for DE-310, a novel camptothecin analog, and two major enzymatic products in human matrices

作者：Soepenberg ; Otto ; de Bruijn ; Peter ; Verweij ; Jaap ; Atsumi ; Ryo ; Sparreboom ; Alex

关键词：Camptothecin ; DE-310

刊名：Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences

出版年：2004

10.The activity profile of the hexacyclic camptothecin derivative DX-8951f in experimental human colon cancer and ovarian cancer

作者：van Hattum ; Annemarie H. ; Pinedo ; Herbert M. ; Schlü ; per ; Hennie M.M. ; Erkelens ; Caroline A.M. ; et. al.

关键词：Pgp ; P170-glycoprotein ; MRP1 ; multidrug resistance-associated protein 1 ; LRP ; lung resistance protein ; BCRP ; Breast Cancer Resistance Protein ; MTT ; (3-(4 ; 5-dimethylthiazol-2-yl)-2 ; 6-dimethyl-morpholino)-2 ; 5-diphenyl-tetrazolium bromide ; RF ; resistance fac

刊名：Biochemical Pharmacology

出版年：2002

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