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Elsevier电子期刊(656)

在“Elsevier电子期刊”中，命中：656条，耗时：小于0.01 秒

在所有数据库中总计命中：656条

1.Subcellular localization of the FLT3-ITD oncogene plays a significant role in the production of NOX- and p22^phox-derived reactive oxygen species in acute myeloid leukemia

作者：Jennifer N. Moloney ; Joanna Stanicka ; Thomas G. Cotter ; ^{t.cotter@ucc.ie}

关键词：FLT3 ; FMS-like tyrosine kinase 3 receptor ; FLT3-ITD ; FLT3-internal tandem duplication ; FLT3-WT ; FLT3- wild type ; NOX ; NADPH oxidase ; p22phox ; p22 phagocyte oxidase ; ROS ; reactive oxygen species ; AML ; acute myeloid leukemia ; ER ; endoplasmic reticulum ; H2O2 ; hydrogen peroxide ; PO1 ; peroxy orange 1 ; RTK ; receptor tyrosine kinase ; COX ; cyclooxygenase ; DUOX ; dual oxidase ; DMSO ; dimethylsulfoxide

刊名：Leukemia Research

出版年：2017

2.Synthetic strategy for increasing solubility of potential FLT3 inhibitor thieno[2,3-d]pyrimidine derivatives through structural modifications at the C₂ and C₆ positions

作者：Changmok Oh^a ; Hyuntae Kim^a ; ^b ; Jong Soon Kang^c ; Jieun Yun^c ; Jaejun Sim^d ; Hwan-Mook Kim^d ; Gyoonhee Han^a ; ^b ; ^{gyoonhee@yonsei.ac.kr}

关键词：FLT3 ; Thieno[2 ; 3-d]pyrimidine ; Acute myeloid leukemia (AML) ; Solubility

刊名：Bioorganic & Medicinal Chemistry Letters

出版年：2017

3.Design, synthesis and biological evaluation of indolin-2-one-based derivatives as potent, selective and efficacious inhibitors of FMS-like tyrosine kinase3 (FLT3)

作者：Fei Ma^a ; Peng Liu^a ; Min Lei^a ; Jian Liu^b ; ^{liujian623@njucm.edu.cn} ; Hongtao Wang^c ; Shaohua Zhao^c ; Lihong Hu^a ; ^b ; ^{lhhu@simm.ac.cn}

关键词：Indolin-2-one derivatives ; FLT3 inhibitors ; Structure-activity relationships (SARs) ; Acute myeloid leukemia (AML) ; In vivo study

刊名：European Journal of Medicinal Chemistry

出版年：2017

4.CPX-351 exhibits potent and direct ex vivo cytotoxicity against AML blasts with enhanced efficacy for cells harboring the FLT3-ITD mutation

作者：Max J. Gordon^a ; Paul Tardi^b ; Marc M. Loriaux^c ; ^g ; Stephen E. Spurgeon^d ; ^g ; Elie Traer^d ; ^g ; Tibor Kovacsovics^e ; Lawrence D. Mayer^b ; Jeffrey W. Tyner^f ; ^g ; ^{tynerj@ohsu.edu}

关键词：CPX-351 ; Cytarabine ; Daunorubicin ; Leukemia ; Cytotoxicity

刊名：Leukemia Research

出版年：2017

5.AC220 and AraC cause differential inhibitory dynamics in patient-derived M5-AML with FLT3-ITD and, thus, ultimately distinct therapeutic outcomes

作者：Xiaoyu An^a ; Jinping Liu^a ; Na Wang^b ; Di Wang^b ; Liang Huang^b ; Likun Zhang^a ; Jie Cai^a ; Jean-Pierre Wery^a ; Demin Zhou^c ; Jianfeng Zhou^b ; Qi-Xiang Li^a ; ^c

刊名：Experimental Hematology

出版年：2017

6.Allogeneic Hematopoietic Stem Cell Transplantation in FLT3-ITD-Positive Acute Myelogenous Leukemia: The Role for FLT3 Tyrosine Kinase Inhibitors Post-Transplantation

作者：Gary J. Schiller¹ ; ^{gschiller@mednet.ucla.edu" class="auth_mail" title="E-mail the corresponding author} ; Pamela Tuttle² ; Pinkal Desai³

关键词：Acute myelogenous leukemia ; Allogeneic hematopoietic stem cell transplantation ; FLT3 ; FLT3-ITD ; Tyrosine kinase inhibitor

刊名：Biology of Blood and Marrow Transplantation

出版年：2016

7.The marine-derived pachycladin diterpenoids as novel inhibitors of wild-type and mutant EGFR

作者：Mohamed M. Mohyeldin ^{mohyelmm@warhawks.ulm.edu} ; Mohamed R. Akl ^{mohamedreda_pharmacy@yahoo.com} ; Abu Bakar Siddique ; Hossam M. Hassan¹ ; ^{abuh20050@yahoo.com} ; Khalid A. El Sayed ; ^{elsayed@ulm.edu}

关键词：ATCC ; American type culture collection ; CD30 ; cluster of differentiation 30 a type I transmembrane glycoprotein belonging to the TNF receptor superfamily ; CD31 ; platelet endothelial cell adhesion molecule 1 ; EGF ; epidermal growth factor ; EPHB4 ; ephrin type-B receptor 4 ; ERK ; extracellular signal-regulated kinase ; FGFR ; fibroblast growth factor receptor ; FLT3 ; fms-related tyrosine kinase 3 ; JAK2 ; janus kinase 2 ; L858R ; leucine 858 mutated to arginine ; L861Q ; leucine 861 mutated to glutamine ; M ; m

刊名：Biochemical Pharmacology

出版年：2017

8.Cabozantinib is selectively cytotoxic in acute myeloid leukemia cells with FLT3-internal tandem duplication (FLT3-ITD)

作者：Jeng-Wei Lu^a ; An-Ni Wang^a ; Heng-An Liao^a ; Chien-Yuan Chen^b ; Hsin-An Hou^b ; Chung-Yi Hu^a ; ^c ; Hwei-Fan Tien^b ; Da-Liang Ou^d ; ^{dlou@ntu.edu.tw" class="auth_mail" title="E-mail the corresponding author} ; Liang-In Lin^a ; ^c ; ^{lilin@ntu.edu.tw" class="auth_mail" title="E-mail the corresponding author}

关键词：Acute myeloid leukemia ; FLT3-ITD ; Cabozantinib

刊名：Cancer Letters

出版年：2016

9.Prevalence and Clinical Significance of FLT3 Mutation Status in Acute Myeloid Leukemia Patients: A Multicenter Study

作者：Jorge Cuervo-Sierra^a ; José ; Carlos Jaime-Pé ; rez^a ; ^{carjaime@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; Ramó ; n A. Martí ; nez-Herná ; ndez^a ; Ricardo D. Garcí ; a-Sepú ; lveda^a ; Mó ; nica Sá ; nchez-Cá ; rdenas^a ; David Gó ; mez-Almaguer^a ; Rocí ; o Ortí ; z-Ló ; pez^b ; Cé ; sar D. Villarreal-Villarreal^a ; Guillermo J. Ruiz-Arguelles^c ; Guillermo Ruiz-Delgado^c ; Julia Lutz-Presno^c ; Javier Garcé ; s-Eisele^c ; ^d ; Gregorio Ignacio-Ibarra^e ; ^f ; Gabriel Muciñ ; o-Herná ; ndez^e ; ^g ; Rosa M. Arana-Trejo^e ; ^g ; Angé ; lica M. Jimé ; nez-Mejia^h ; Gonzalo Vá ; squez-Palacio^h

关键词：Acute myeloid leukemia ; AML ; FLT3 ; Latin America

刊名：Archives of Medical Research

出版年：2016

10.Allogeneic Transplantation in First Remission Improves Outcomes Irrespective of FLT3-ITD Allelic Ratio in FLT3-ITD-Positive Acute Myelogenous Leukemia

作者：Betü ; l Oran¹ ; ^{boran@mdanderson.org" class="auth_mail" title="E-mail the corresponding author} ; Jorge Cortes² ; Amer Beitinjaneh³ ; Hsiang-Chun Chen⁴ ; Marcos de Lima⁵ ; Keyur Patel⁶ ; Farhad Ravandi² ; Xuemei Wang⁴ ; Mark Brandt² ; Borje S. Andersson¹ ; Stefan Ciurea¹ ; Fabio P. Santos² ; Leandro de Padua Silva¹ ; Elizabeth J. Shpall¹ ; Richard E. Champlin¹ ; Hagop Kantarjian² ; Gautam Borthakur²

关键词：AML ; FLT3-ITD mutation ; Allogeneic stem cell transplantation ; Postremission therapy

刊名：Biology of Blood and Marrow Transplantation

出版年：2016

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