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Springer电子图书(1)
NATURE电子期刊(2)
ACS电子期刊(6)
SpringerLink电子期刊(40)
Elsevier电子期刊(101)
在“
Elsevier电子期刊
”中,
命中:
101
条,耗时:0.0119927 秒
在所有数据库中总计命中:
150
条
1.
The dual enzyme LRRK2 hydrolyzes GTP in both its GTPase and kinase domains in vitro
作者:
Zhiyong Liu
;
Andrew B. West
;
abwest@uab.edu
关键词:
PARK8
;
ROCO4
;
Dardarin
;
Enzyme kinetics
;
Manganese
;
Nucleotide-binding pocket
刊名:Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
出版年:2017
2.
Mitochondrial DNA in CSF distinguishes LRRK2 from idiopathic Parkinson's disease
作者:
Petar Podlesniy
a
;
d
;
Dolores Vilas
b
;
Peggy Taylor
e
;
Leslie M. Shaw
f
;
Eduard Tolosa
b
;
c
;
d
;
Ramon Trullas
a
;
c
;
d
;
ramon.trullas@iibb.csic.es" class="auth_mail" title="E-mail the corresponding author
关键词:
mtDNA
;
mitochondrial DNA
;
ddPCR
;
digital droplet PCR
;
NMNC
;
non-manifesting non-carriers (subjects who do not carry the LRRK2
G2019S
mutation
and do not manifest Parkinson's disease)
;
NMC
;
non-manifesting carriers (subjects who carry the LRRK2
G2019S
mutation
and do not manifest Parkinson's disease)
;
LRRK2-PD
;
subjects who carry the LRRK2
G2019S
mutation
and have Parkinson's disease
;
IPD
;
subjects who have a confirmed clinical diagnosis of Parkinson's disease but do not carry the LRRK2
G2019S
mutati
刊名:Neurobiology of Disease
出版年:2016
3.
Comparative blood transcriptome analysis in idiopathic and LRRK2
G2019S
-associated Parkinson's disease
作者:
Jon Infante
a
;
b
;
jinfante@humv.es" class="auth_mail" title="E-mail the corresponding author
;
Carlos Prieto
c
;
Marí
;
a Sierra
a
;
b
;
Pascual Sá
;
nchez-Juan
a
;
b
;
Isabel Gonzá
;
lez-Aramburu
a
;
b
;
Coro Sá
;
nchez-Quintana
a
;
José
;
Berciano
a
;
b
;
Onofre Combarros
a
;
b
;
Jesú
;
s Sainz
d
关键词:
Parkinson's disease
;
LRRK2
;
Gene expression
;
RNA-seq
;
Trancriptome
;
Peripheral blood
刊名:Neurobiology of Aging
出版年:2016
4.
Analysis of the genetic variability in Parkinson's disease from Southern Spain
作者:
Sara Bandré
;
s-Ciga
a
;
Niccolò
;
Emmanuele Mencacci
b
;
Raquel Durá
;
n
a
;
Francisco Javier Barrero
c
;
Francisco Escamilla-Sevilla
d
;
Sarah Morgan
b
;
Jason Hehir
b
;
Francisco Vives
a
;
John Hardy
b
;
Alan M. Pittman
b
;
a.pittman@ucl.ac.uk" class="auth_mail" title="E-mail the corresponding author
关键词:
Parkinson's disease
;
Genetics
;
Mutation
s
;
Southern Spain population
;
Next-generation sequencing
刊名:Neurobiology of Aging
出版年:2016
5.
LRRK2
G2019S
transgenic mice display increased susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-mediated neurotoxicity
作者:
Senthilkumar S. Karuppagounder
a
;
b
;
h
;
Yulan Xiong
a
;
b
;
h
;
1
;
Yunjong Lee
a
;
b
;
h
;
2
;
Maeve C. Lawless
a
;
g
;
h
;
Donghyun Kim
a
;
b
;
Emily Nordquist
a
;
f
;
Ian Martin
a
;
b
;
h
;
3
;
Preston Ge
a
;
f
;
Saurav Brahmachari
a
;
b
;
h
;
Aanishaa Jhaldiyal
a
;
h
;
Manoj Kumar
a
;
b
;
h
;
Shaida A. Andrabi
a
;
b
;
h
;
Ted M. Dawson
a
;
b
;
c
;
e
;
h
;
tdawson@jhmi.edu" class="auth_mail" title="E-mail the corresponding author
;
Valina L. Dawson
a
;
b
;
d
;
e
;
h
;
vdawson@jhmi.edu" class="auth_mail" title="E-mail the corresponding author
关键词:
Parkinson&rsquo
;
s Disease
;
LRRK2
;
Dopamine
;
Stereology
;
MPTP
;
Genetic factor
;
Environmental factor
刊名:Journal of Chemical Neuroanatomy
出版年:2016
6.
Targeting the cannabinoid CB
2
receptor to attenuate the progression of motor deficits in LRRK2-transgenic mice
作者:
Cristina Palomo-Garo
a
;
b
;
c
;
Yolanda Gó
;
mez-Gá
;
lvez
a
;
b
;
c
;
2
;
Concepció
;
n Garcí
;
a
a
;
b
;
c
;
1
;
conchig@med.ucm.es" class="auth_mail" title="E-mail the corresponding author
;
Javier Ferná
;
ndez-Ruiz
a
;
b
;
c
;
1
;
jjfr@med.ucm.es" class="auth_mail" title="E-mail the corresponding author
关键词:
Cannabinoids
;
Endocannabinoid signaling system
;
CB2 receptors
;
Parkinson&rsquo
;
disease
;
LRRK2-transgenic mice
;
Autophagy
刊名:Pharmacological Research
出版年:2016
7.
LRRK2 variation and dementia with Lewy bodies
作者:
Michael G. Heckman
a
;
1
;
heckman.michael@mayo.edu" class="auth_mail" title="E-mail the corresponding author
;
Alexandra I. Soto-Ortolaza
b
;
1
;
Monica Y. Sanchez Contreras
b
;
Melissa E. Murray
b
;
Otto Pedraza
d
;
Nancy N. Diehl
a
;
Ronald Walton
b
;
Catherine Labbé
;
b
;
Oswaldo Lorenzo-Betancor
b
;
Ryan J. Uitti
e
;
Jay van Gerpen
e
;
Nilü
;
fer Ertekin-Taner
e
;
Glenn E. Smith
f
;
Kejal Kantarci
g
;
Rodolfo Savica
h
;
David T. Jones
h
;
Jonathan Graff-Radford
h
;
David S. Knopman
h
;
Val J. Lowe
g
;
Clifford R. Jack Jr.
g
;
Ronald C. Petersen
h
;
Joseph E. Parisi
h
;
i
;
Rosa Rademakers
b
;
Zbigniew K. Wszolek
e
;
Neill R. Graff-Radford
e
;
Tanis J. Ferman
d
;
Dennis W. Dickson
b
;
Bradley F. Boeve
h
;
Owen A. Ross
b
;
c
;
j
;
k
关键词:
Dementia with Lewy bodies
;
Genetics
;
LRRK2
;
Parkinson's disease
刊名:Parkinsonism & Related Disorders
出版年:2016
8.
Clinical and imaging markers in premotor LRRK2
G2019S
mutation
carriers
作者:
Dolores Vilas
a
;
Lourdes Ispierto
d
;
Ramiro Á
;
lvarez
d
;
Claustre Pont-Sunyer
a
;
Marí
;
a José
;
Martí
;
a
;
b
;
c
;
Francesc Valldeoriola
a
;
b
;
c
;
Yaroslau Compta
a
;
b
;
c
;
Oriol de Fabregues
e
;
Jorge Herná
;
ndez-Vara
e
;
Ví
;
ctor Puente
f
;
Matilde Calopa
g
;
Serge Jaumà
;
g
;
Jaume Campdelacreu
g
;
Miquel Aguilar
h
;
Pilar Quí
;
lez
h
;
Pilar Casquero
i
;
Francisco Lomeñ
;
a
j
;
José
;
Rí
;
os
k
;
l
;
Eduardo Tolosa
a
;
b
;
c
;
etolosa@clinic.ub.es" class="auth_mail" title="E-mail the corresponding author
关键词:
Parkinson
;
LRRK2
;
Genetic
;
Transcranial ultrasound
;
Substantia nigra
刊名:Parkinsonism & Related Disorders
出版年:2015
9.
Neurite Aggregation and Calcium Dysfunction in iPSC-Derived Sensory Neurons with Parkinson’s Disease-Related LRRK2
G2019S
Mutation
作者:
Andrew J. Schwab
1
;
Allison D. Ebert
1
;
aebert@mcw.edu" class="auth_mail" title="E-mail the corresponding author
刊名:Stem Cell Reports
出版年:2015
10.
LRRK2
mutation
s cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: Reversal by gene correction
作者:
Laurie H. S
;
ers
;
Jos茅e Lagani猫re
;
Oliver Cooper
;
Sally K. Mak
;
B. Joseph Vu
;
Y. Anne Huang
;
David E. Paschon
;
Malini Vangipuram
;
Ramya Sundararajan
;
Fyodor D. Urnov
;
J. William Langston
;
Philip D. Gregory
;
H. Steve Zhang
;
J. Timothy Greenamyre
;
Ole Isacson
;
Birgitt Sch眉le
关键词:
Parkinson's disease
;
LRRK2
;
Mitochondrial DNA damage
;
Stem cells
刊名:Neurobiology of Disease
出版年:February, 2014
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