设为首页
收藏本站
网站地图
|
English
|
公务邮箱
About the library
Background
History
Leadership
Organization
Readers' Guide
Opening Hours
Collections
Help Via Email
Publications
Electronic Information Resources
常用资源
电子图书
期刊论文
学位会议
外文资源
特色专题
内部出版物
Wiley电子期刊(16)
NATURE电子期刊(11)
ACS电子期刊(247)
SpringerLink电子期刊(368)
Elsevier电子期刊(1333)
在“
Elsevier电子期刊
”中,
命中:
1,333
条,耗时:0.0259881 秒
在所有数据库中总计命中:
1,975
条
1.
Towards the development of activity-based probes for detection of lysine-specific demethylase-1 activity
作者:
Maria E. Ourailidou
a
;
Alessia Lenoci
b
;
Clemens Zwergel
b
;
Dante Rotili
b
;
Antonello Mai
b
;
c
;
antonello.mai@uniroma1.it
;
Frank J. Dekker
a
;
f.j.dekker@rug.nl
关键词:
Lysine demethylation
;
Tumorigenesis
;
Tranylcypromine
;
Irreversible
inhibition
;
Enzyme labeling
刊名:Bioorganic & Medicinal Chemistry
出版年:2017
2.
mTOR
Inhibition
Mitigates Molecular and Biochemical Alterations of Vigabatrin-Induced Visual Field Toxicity in Mice
作者:
Kara R. Vogel
;
PhD
a
;
Garrett R. Ainslie
;
PhD
a
;
Michelle A. Schmidt
;
MS
b
;
Jonathan P. Wisor
;
PhD
b
;
K. Michael Gibson
;
PhD
a
;
mike.gibson@wsu.edu
关键词:
vigabatrin
;
GABA
;
mTOR
;
gene expression
;
visual evoked potentials
;
visual field loss
;
ARPE19 cells
;
epilepsy
刊名:Pediatric Neurology
出版年:2017
3.
Irreversible
electroporation inhibits pro-cancer inflammatory signaling in triple negative breast cancer cells
作者:
Ishan Goswami
a
Author Vitae
;
Sheryl Coutermarsh-Ott
c
Author Vitae
;
Ryan G. Morrison
b
Author Vitae
;
Irving C. Allen
c
Author Vitae
;
Rafael V. Davalos
a
;
b
;
d
Author Vitae
;
Scott S. Verbridge
b
;
d
;
sverb@vt.edu" class="auth_mail" title="E-mail the corresponding author
Author Vitae
;
Lissett R. Bickford
a
;
b
;
d
Author Vitae
关键词:
Electroporation
;
Triple negative breast cancer
;
Thymic stromal lymphopoietin (TSLP)
;
Immunotherapy
刊名:Bioelectrochemistry
出版年:2017
4.
Inhibiting medial septal cholinergic neurons with DREADD alleviated anxiety-like behaviors in mice
作者:
Yu Zhang
a
;
Ying-Ying Jiang
a
;
Shan Shao
a
;
Chan Zhang
a
;
Feng-Yu Liu
a
;
You Wan
a
;
b
;
c
;
Ming Yi
a
;
mingyi@bjmu.edu.cn
关键词:
ChAT
;
choline acetyltransferase
;
CNO
;
clozapine N-oxide
;
DREADD
;
designer receptors exclusively activated by designer drugs
;
EPM
;
elevated plus-maze
;
MB
;
marble burying
;
MS
;
medial septum
;
NSF
;
novelty-suppressed feeding
;
OF
;
open field
;
PFA
;
paraformaldehyde
;
PV
;
parvalbumin
;
SAP
;
192 IgG-saporin
刊名:Neuroscience Letters
出版年:2017
5.
The performance of activated sludge exposed to arsanilic acid and amprolium hydrochloride in sequencing batch reactors
作者:
Kui Chen
a
;
Feng Ji
b
;
Shoujun Yuan
a
;
d
;
Wentao Hao
c
;
Wei Wang
a
;
d
;
dwhit@126.com
;
Zhen-Hu Hu
a
;
d
;
zhhu@hfut.edu.cn
关键词:
Activated sludge
;
Arsanilic acid (ASA)
;
Amprolium hydrochloride (AMP)
;
Nutrient removal
刊名:International Biodeterioration & Biodegradation
出版年:2017
6.
Proteasome
inhibition
by new dual warhead containing peptido vinyl sulfonyl fluorides
作者:
Arwin J. Brouwer
a
;
&dagger
;
;
Natalia Herrero Á
;
lvarez
b
;
&dagger
;
;
Adriano Ciaffoni
a
;
Helmus van de Langemheen
b
;
Rob M.J. Liskamp
a
;
b
;
r.m.j.liskamp@uu.nl" class="auth_mail" title="E-mail the corresponding author
;
Robert.liskamp@glasgow.ac.uk" class="auth_mail" title="E-mail the corresponding author
关键词:
Drug design
;
Peptido vinyl sulfonyl fluoride
;
Proteasome
;
Irreversible
inhibition
;
Dual warhead
刊名:Bioorganic & Medicinal Chemistry
出版年:2016
7.
Synthesis, structural characterization, docking, lipophilicity and cytotoxicity of 1-[(1R)-1-(6-fluoro-1,3-benzothiazol-2-yl)ethyl]-3-alkyl carbamates, novel acetylcholinesterase and butyrylcholinesterase pseudo-
irreversible
inhibitors
作者:
Vladimí
;
r Pejchal
a
;
vladimir.pejchal@upce.cz" class="auth_mail" title="E-mail the corresponding author
;
&Scaron
;
á
;
rka &Scaron
;
těpá
;
nková
;
b
;
Marcela Pejchalová
;
b
;
Karel Krá
;
lovec
b
;
Radim Havelek
b
;
Zdeňka Růžičková
;
c
;
Haresh Ajani
d
;
e
;
Rabindranath Lo
d
;
Martin Lep&scaron
;
í
;
k
d
关键词:
Halogenated benzothiazole
;
Carbamates
;
Acetylcholinesterase
;
Butyrylcholinesterase
inhibition
;
Pseudo-
irreversible
mechanism
;
Covalent docking
刊名:Bioorganic & Medicinal Chemistry
出版年:2016
8.
Immune-related endocrine disorders in novel immune checkpoint
inhibition
therapy
作者:
Le Min
lmin@bwh.harvard.edu
关键词:
Cancer
;
Hypophysitis
;
Immune checkpoint
inhibition
;
Immune-related adverse events
;
Thyroiditis
刊名:Genes & Diseases
出版年:2016
9.
Multiple modes of
inhibition
of human cytochrome P450 2J2 by dronedarone, amiodarone and their active metabolites
作者:
Aneesh Karkhanis
a
;
Hui Yuan Lam
a
;
Gopalakrishnan Venkatesan
a
;
Siew Kwan Koh
b
;
Christina Li Lin Chai
a
;
Lei Zhou
b
;
Yanjun Hong
a
;
Pipin Kojodjojo
c
;
Eric Chun Yong Chan
a
;
phaccye@nus.edu.sg" class="auth_mail" title="E-mail the corresponding author
关键词:
AA
;
arachidonic acid
;
ACN
;
acetonitrile
;
AF
;
atrial fibrillation
;
CYP2D6
;
cytochrome P450 2D6
;
CYP2J2
;
cytochrome P450 2J2
;
CYP3A4
;
cytochrome P450 3A4
;
CYP3A5
;
cytochrome P450 3A5
;
DDI
;
drug&ndash
;
drug interaction
;
EET
;
epoxyeicosatrienoic acid
;
GSH
;
glutathione
;
k
;
intrinsic elimination rate constant
;
Ki
;
reversible
inhibition
constant
;
KI
;
inactivator concentration at half-maximum inactivation rate constant
;
kinact
;
maximum inactivation rate constant
;
Km
;
Michaelis&ndash
;
Menten constant
;
Kobs
刊名:Biochemical Pharmacology
出版年:2016
10.
Design, synthesis and biological evaluation of N-methyl-N-[(1,2,3-triazol-4-yl)alkyl]propargylamines as novel monoamine oxidase B inhibitors
作者:
Ornella Di Pietro
a
;
Nelson Alencar
b
;
Gerard Esteban
c
;
Elisabet Viayna
a
;
Natalia Szałaj
a
;
Javier Vá
;
zquez
b
;
Jordi Juá
;
rez-Jimé
;
nez
b
;
Irene Sola
a
;
Belé
;
n Pé
;
rez
d
;
Montse Solé
;
c
;
Mercedes Unzeta
c
;
Diego Muñ
;
oz-Torrero
a
;
dmunoztorrero@ub.edu" class="auth_mail" title="E-mail the corresponding author
;
F. Javier Luque
b
;
fjluque@ub.edu" class="auth_mail" title="E-mail the corresponding author
关键词:
Click-chemistry
;
Monoamine oxidase B
;
Alzheimer&rsquo
;
s disease
;
Irreversible
inhibition
刊名:Bioorganic & Medicinal Chemistry
出版年:2016
1
2
3
4
5
6
7
8
9
按检索点细分(1333)
题名(61)
关键词(33)
文摘(1186)
按出版年细分(1333)
2027年及以后(26)
2017年(5)
2016年(33)
2015年(9)
2014年(1)
2013年(62)
2012年(60)
2011年(67)
2010年(68)
2009年(44)
2008年(62)
2007年(65)
2006年(49)
2005年(69)
2004年(57)
2003年(49)
2002年(65)
2001年(74)
2000年(70)
2000年及以前(398)
NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via
email
.