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内部出版物
Wiley电子期刊(3)
Elsevier电子期刊(11)
ACS电子期刊(2)
在“
Elsevier电子期刊
”中,
命中:
11
条,耗时:小于0.01 秒
在所有数据库中总计命中:
16
条
1.
Discovery of a novel class of highly potent inhibitors of the p53-MDM2 interaction by structure-based design starting from a conformational argument
作者:
Pascal Furet
;
pascal.furet@novartis.com" class="auth_mail" title="E-mail the corresponding author
;
Keiichi Masuya
;
Joerg
Kallen
;
Thé
;
rè
;
se Stachyra-Valat
;
Stephan Ruetz
;
Vito Guagnano
;
Philipp Holzer
;
Robert Mah
;
Stefan Stutz
;
Andrea Vaupel
;
Patrick Chè
;
ne
;
Sé
;
bastien Jeay
;
Achim Schlapbach
关键词:
p53&ndash
;
MDM2 inhibitors
;
Protein&ndash
;
protein interaction inhibitors
;
Anticancer agents
;
Structure-based design
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2016
2.
Tetra-substituted imidazoles as a new class of inhibitors of the p53-MDM2 interaction
作者:
Andrea Vaupel
;
andrea.vaupel@novartis.com" class="auth_mail
;
Guido Bold
;
Alain De Pover
;
Thé
;
rè
;
se Stachyra-Valat
;
Joanna Hergovich-Lisztwan
;
Joerg
Kallen
;
Keiichi Masuya
;
Pascal Furet
;
pascal.furet@novartis.com" class="auth_mail
关键词:
Protein&ndash
;
protein interaction inhibitors
;
Structure-based design
;
p53
;
MDM2
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:1 May, 2014
3.
The central valine concept provides an entry in a new class of non peptide inhibitors of the p53-MDM2 interaction
作者:
Pascal Furet
;
pascal.furet@novartis.com
;
Patrick Chè
;
ne
;
Alain De Pover
;
Thé
;
rè
;
se Stachyra Valat
;
Joanna Hergovich Lisztwan
;
Joerg
Kallen
;
Keiichi Masuya
关键词:
p53&ndash
;
MDM2 inhibitors
;
Protein&ndash
;
protein interaction inhibitors
;
Anticancer agents
;
Structure-based design
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2012
4.
The X-ray Crystal Structure of the First RNA Recognition Motif and Site-Directed Mutagenesis Suggest a Possible HuR Redox Sensing Mechanism
作者:
Roger Marc Benoit
;
Nicole-Claudia Meisner
;
Joerg
Kallen
;
Patrick Graff
;
René
;
Hemmig
;
Ré
;
gis Cè
;
be
;
Christian Ostermeier
;
Hans Widmer
;
Manfred Auer
关键词:
HuR
;
RNA-recognition motif
;
redox regulation
;
dimerization
刊名:Journal of Molecular Biology
出版年:2010
5.
Inhibition of Interleukin-6-Transsignaling via gp130-Fc in Hemorrhagic Shock and Sepsis
作者:
Soeren Torge Mees
;
Sietje Toellner
;
Kerstin Marx
;
Fred Faendrich
;
Karl Josef
Kallen
;
Joerg
Schroeder
;
Joerg
Haier
;
Volker Kahlke
关键词:
cytokines
;
cytokine receptors
;
soluble receptors
刊名:Journal of Surgical Research
出版年:2009
6.
1,4-Diazepane-2,5-diones as novel inhibitors of LFA-1
作者:
Wattanasin
;
Sompong
;
Kallen
;
Joerg
;
Myers
;
Stewart
;
Guo
;
Qin
;
Sabio
;
Michael
;
Ehrhardt
;
Claus
;
et. al.
关键词:
Integrin
;
LFA-1
;
Diazepanediones
;
I-domain
;
L-site binding
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2005
7.
Identification of natural ligands of retinoic acid receptor-related orphan receptor α ligand-binding domain expressed in Sf9 cells––a mass spectrometry approach
作者:
Bitsch
;
Francis
;
Aichholz
;
Reiner
;
Kallen
;
Joerg
;
Geisse
;
Sabine
;
Fournier
;
Brigitte
;
Schlaeppi
;
Jean-Marc
关键词:
Mass spectrometry
;
Electrospray ionization
;
Noncovalent complex
;
Retinoic acid receptor-related orphan receptor alpha
;
RORα
;
Cholesterol
刊名:Analytical Biochemistry
出版年:2003
8.
X-Ray Structure of the hRORα LBD at 1.63 Å: Structural and Functional Data that Cholesterol or a Cholesterol Derivative Is the Natural Ligand of RORα
作者:
Kallen
;
Joerg
A.
;
et. al.
关键词:
ROR
;
atherosclerosis
;
cholesterol
;
nuclear receptor
;
coactivator
;
transcription factor
刊名:Structure
出版年:2002
9.
X-Ray Structure of the hRORα LBD at 1.63 Å: Structural and Functional Data that Cholesterol or a Cholesterol Derivative Is the Natural Ligand of RORα
作者:
Kallen
;
Joerg
A.
;
et. al.
关键词:
ROR
;
atherosclerosis
;
cholesterol
;
nuclear receptor
;
coactivator
;
transcription factor
刊名:Structure
出版年:2002
10.
Conformational differences of an immunosuppressant peptolide in a single crystal and in a crystal complex with human cyclophilin A
作者:
Mikol
;
Vincent
;
Taylor
;
Paul
;
Kallen
;
Joerg
;
Walkinshaw
;
Malcolm D.
关键词:
immunophilin
;
peptolide-214103
;
cyclosporin A
;
cyclophilin
;
ligand binding
;
CsA
;
cyclosporin A
;
CypA
;
cyclophilin A
;
DMSO
;
dimethyl sulphoxide
刊名:Journal of Molecular Biology
出版年:1998
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