设为首页
收藏本站
网站地图
|
English
|
公务邮箱
About the library
Background
History
Leadership
Organization
Readers' Guide
Opening Hours
Collections
Help Via Email
Publications
Electronic Information Resources
常用资源
电子图书
期刊论文
学位会议
外文资源
特色专题
内部出版物
SpringerLink电子期刊(120)
NATURE电子期刊(1)
Elsevier电子期刊(257)
ACS电子期刊(13)
在“
Elsevier电子期刊
”中，
命中：
257
条，耗时：0.0209929 秒
在所有数据库中总计命中：
391
条
1.
Engineered
Liver
Pl
a
tforms for Different Ph
a
ses of Drug Development
作者：
Brent
on
R. W
a
re
1
;
2
;
S
a
lm
a
n R. Khet
a
ni
2
;
skhet
a
ni@uic.edu
关键词：
liver
-
on
-
a
-
chip
;
microf
a
bric
a
ti
on
;
microp
a
tterned co-cultures
;
drug-induced
liver
injury
;
prim
a
ry hum
a
n hep
a
tocytes
刊名：Trends in Biotechnology
出版年：2017
2.
Ch
a
r
a
cteriz
a
ti
on
of stem cell-derived
liver
a
nd intestin
a
l org
a
noids
a
s
a
model system to study nucle
a
r receptor biology
作者：
Ingrid T.G.W. Bijsm
a
ns
a
;
A
lex
a
ndr
a
Mil
ona
a
;
Noortje Ijssenn
a
gger
a
;
Ellen C.L. Willemsen
a
;
Jos&e
a
cute
;
M. R
a
mos Pittol
a
;
Joh
a
n W. J
on
ker
b
;
K
a
tj
a
L
a
nge
c
;
Guido J.E.J. Hooiveld
c
;
S
a
ski
a
W.C. v
a
n Mil
a
;
S.W.C.v
a
nMil@umcutrecht.nl
关键词：
ChIP
;
chrom
a
tin immunoprecipit
a
ti
on
;
DIC
;
differenti
a
l interference c
on
tr
a
st
;
DM
;
differenti
a
ti
on
medium
;
DSG
;
Di(N-succinimidyl) glut
a
r
a
te
;
EM
;
exp
a
nsi
on
medium
;
Fxr
;
f
a
rnesoid x receptor
;
IP
A
;
Ingenuity P
a
thw
a
y An
a
lysis
;
Lxr
;
Liver
x receptor
;
NR
;
nucle
a
r receptor
;
OC
A
;
obeticholic
a
cid
;
Pp
a
r
;
Peroxisome prolifer
a
tor-
a
ctiv
a
ted receptor
;
RM
A
;
robust multi
a
rr
a
y
a
n
a
lysis
;
Rosi
;
Rosiglit
a
z
on
e
刊名：Biochimic
a
et Biophysic
a
Act
a
(BBA) - Molecul
a
r B
a
sis of Dise
a
se
出版年：2017
3.
Structure-
a
ctivity rel
a
ti
on
ship for br
a
nched oxyquinoline HIF
a
ctiv
a
tors: Effect of modific
a
ti
on
s to phenyl
a
cet
a
mide “t
a
il”
作者：
A
.A. Poloznikov
a
;
a
ndrey.poloznikov@gm
a
il.com
;
A
.A. Z
a
kh
a
ri
a
nts
b
;
S.V. Nikulin
a
;
c
;
N.
A
. Smirnov
a
a
;
D.M. Hushpuli
a
n
a
;
I.N. G
a
isin
a
d
;
A
.G. T
on
evitsky
b
;
V.I. Tishkov
e
;
f
;
g
;
I.G. G
a
z
a
ry
a
n
a
;
f
关键词：
7-Substituted 8-hydroxyquinoline
;
HIF prolyl hydroxyl
a
se
;
HIF1 ODD-luc reporter
;
Lucifer
a
se
a
ss
a
y
;
Liver
-
on
-
a
-
chip
;
Hep
a
totoxicity
刊名：Biochimie
出版年：2017
4.
A
Bioprinted
Liver
-
on
-
a
-
Chip
for Drug Screening Applic
a
ti
on
s
作者：
Steph
a
nie Knowlt
on
1
;
S
a
v
a
s T
a
soglu
1
;
2
;
s
a
v
a
s@engr.uc
on
n.edu" cl
a
ss="
a
uth_m
a
il" title="E-m
a
il the corresp
on
ding
a
uthor
关键词：
tissue engineering
;
bioprinting
;
3D cell cultures
;
liver
tissue engineering
;
org
a
n-
on
-
a
-
chip
;
microfluidics
刊名：Trends in Biotechnology
出版年：2016
5.
Gene expressi
on
profiling in hum
a
n precisi
on
cut
liver
slices in resp
on
se to the FXR
a
g
on
ist obeticholic
a
cid
作者：
Noortje Ijssenn
a
gger
1
;
Aa
fke W.F. J
a
nssen
2
;
A
lex
a
ndr
a
Mil
ona
1
;
Jos&e
a
cute
;
M. R
a
mos Pittol
1
;
D
a
nielle A.A. Hollm
a
n
1
;
Mich
a
l Mokry
3
;
B
a
rk Betzel
4
;
Frits J. Berends
4
;
Ign
a
ce M. J
a
nssen
4
;
S
a
ski
a
W.C. v
a
n Mil
1
;
&d
a
gger
;
;
S.W.C.v
a
nmil@umcutrecht.nl" cl
a
ss="
a
uth_m
a
il" title="E-m
a
il the corresp
on
ding
a
uthor
;
S
a
nder Kersten
2
;
&d
a
gger
;
关键词：
FXR
;
f
a
rnesoid X Receptor
;
OC
A
;
obeticholic
a
cid
;
N
A
SH
;
n
on
-
a
lcoholic ste
a
tohep
a
titis
;
hPCLS
;
hum
a
n precisi
on
cut
liver
slices
;
LDL
;
low density lipoprotein
;
HDL
;
high density lipoprotein
;
N
A
FLD
;
n
on
-
a
lcoholic f
a
tty
liver
dise
a
se
;
DMSO
;
dimethyl sulfoxide
;
WT
;
wild-type
;
RM
A
;
robust multi-
a
rr
a
y
a
n
a
lysis
;
IBMT
;
Intensity-B
a
sed Moder
a
ted T-st
a
tistic
;
bp
;
b
a
se p
a
ir
;
TSS
;
tr
a
nscripti
on
st
a
rt site
;
IR1
;
inverted NR-hex
a
mer sequence
刊名：Journ
a
l of Hep
a
tology
出版年：2016
6.
Protective effects of curcumin
a
g
a
inst
liver
fibrosis through modul
a
ting DNA methyl
a
ti
on
作者：
Peng WU
a
;
b
;
Rui HU
A
NG
a
;
Y
a
-Li XI
ON
G
a
;
Ch
a
o WU
c
;
dr.wu@nju.edu.cn" cl
a
ss="
a
uth_m
a
il" title="E-m
a
il the corresp
on
ding
a
uthor
关键词：
Liver
fibrosis
;
Curcumin
;
DN
A
methyl
a
ti
on
;
Ther
a
py
刊名：Chinese Journ
a
l of N
a
tur
a
l Medicines
出版年：2016
7.
Infl
a
mm
a
tory regul
a
ti
on
of steroid sulf
a
t
a
se: A novel mech
a
nism to c
on
trol estrogen homeost
a
sis
a
nd infl
a
mm
a
ti
on
in chr
on
ic
liver
dise
a
se
作者：
Mengxi Ji
a
ng
1
;
M
a
rcus Klein
2
;
3
;
Ulrich M. Z
a
nger
2
;
3
;
Moh
a
mm
a
d K. Moh
a
mm
a
d
4
;
M
a
tthew C. C
a
ve
4
;
Nilesh W. G
a
ikw
a
d
5
;
N
a
t
a
sh
a
J. Di
a
s
6
;
Kyle W. Selcer
6
;
Y
a
n Guo
1
;
7
;
Jinh
a
n He
8
;
Xiuhui Zh
a
ng
9
;
Qiujin Shen
10
;
Wenxin Qin
10
;
Ji
a
ng Li
1
;
S
on
g Li
1
;
Wen Xie
1
;
11
;
wex6@pitt.edu" cl
a
ss="
a
uth_m
a
il" title="E-m
a
il the corresp
on
ding
a
uthor
关键词：
ChIP
;
chrom
a
tin immunoprecipit
a
ti
on
;
CRP
;
C-re
a
ctive protein
;
CYP
;
cytochrome P450
;
E2
;
estr
a
diol
;
E2S
;
estr
a
diol sulf
a
te
;
EMS
A
;
electrophoretic mobility shift
a
ss
a
y
;
ER
;
estrogen receptor
;
EST
;
estrogen sulfotr
a
nsfer
a
se
;
FBS
;
fet
a
l bovine serum
;
HPH
;
hum
a
n prim
a
ry hep
a
tocytes
;
ICI
;
ICI 182
;
780
;
IHC
;
immunohistochemistry
;
IL-8
;
interleukin-8
;
IKK
;
IκB kin
a
se
;
LPS
;
lipopolys
a
cch
a
ride
;
MCP-1
;
m
on
ocyte chemot
a
ctic protein-1
;
PDTC
;
pyrrolidine dithioc
a
rb
a
m
a
te
;
PM
A
;
phorbol 12-myrist
a
te 13-
a
cet
a
te
;
S
刊名：Journ
a
l of Hep
a
tology
出版年：2016
8.
A
MPK
a
ctiv
a
tes LXRα
a
nd ABCA1 expressi
on
in hum
a
n m
a
croph
a
ges
作者：
M
a
rin
a
Kemmerer
a
;
Ilk
a
Wittig
b
;
Flori
a
n Richter
b
;
Bernh
a
rd Brü
;
ne
a
;
1
;
Dmitry N
a
mg
a
l
a
dze
a
;
1
;
n
a
mg
a
l
a
dze@biochem.uni-fr
a
nkfurt.de" cl
a
ss="
a
uth_m
a
il" title="E-m
a
il the corresp
on
ding
a
uthor
关键词：
A
BC
;
A
TP-binding c
a
ssette
;
A
CC
;
a
cetyl-CoA c
a
rboxyl
a
se
;
A
MPK
;
A
MP-
a
ctiv
a
ted protein kin
a
se
;
A
TF1
;
a
ctiv
a
ting tr
a
nscripti
on
f
a
ctor-1
;
ChIP
;
chrom
a
tin immunoprecipit
a
ti
on
;
CV
;
c
on
trol virus
;
ERK
;
extr
a
cellul
a
r-sign
a
l regul
a
ted kin
a
se
;
HD
A
C
;
hist
on
e de
a
cetyl
a
se
;
KD
;
knockdown
;
LXR
;
liver
X receptor
;
LXRE
;
LXR resp
on
se element
;
mTOR
;
mech
a
nistic t
a
rget of r
a
p
a
mycin
;
NCOR1
;
nucle
a
r receptor corepressor 1
;
PP
A
R
;
peroxisome prolifer
a
tor-
a
ctiv
a
ted receptor
;
PTM
;
post-tr
a
nsl
a
ti
ona
l modific
a
ti
on
刊名：Intern
a
ti
ona
l Journ
a
l of Biochemistry
a
nd Cell Biology
出版年：2016
9.
Micro
a
rr
a
y
a
n
a
lysis of gene expressi
on
in olive flounder
liver
infected with vir
a
l h
a
emorrh
a
gic septic
a
emi
a
virus (VHSV)
作者：
Hyun Kook Cho
a
;
Jul
a
n Kim
a
;
Ji Young Mo
on
a
;
Bo-Hye N
a
m
a
;
Young-Ok Kim
a
;
Woo-Jin Kim
a
;
Jung Youn P
a
rk
a
;
Cheul Min
A
n
a
;
J
a
ehun Che
on
g
b
;
Hee Je
on
g K
on
g
a
;
heejk
on
g@kore
a
.kr" cl
a
ss="
a
uth_m
a
il" title="E-m
a
il the corresp
on
ding
a
uthor
关键词：
Vir
a
l hemorrh
a
gic septicemi
a
virus
;
Olive flounder
;
P
a
r
a
lichthys oliv
a
ceus
;
Micro
a
rr
a
y
a
n
a
lysis
;
Gene expressi
on
;
Immune resp
on
se
;
Cell cycle
;
Energy met
a
bolism
刊名：Fish & Shellfish Immunology
出版年：2016
10.
Upregul
a
ti
on
of miR-125b by estrogen protects
a
g
a
inst n
on
-
a
lcoholic f
a
tty
liver
in fem
a
le mice
作者：
Zhi-Chun Zh
a
ng
1
;
Y
a
n Liu
1
;
Liu-Ling Xi
a
o
1
;
Shu-Fen Li
1
;
Jing-Hui Ji
a
ng
1
;
Yue Zh
a
o
1
;
Shu-Wen Qi
a
n
1
;
Qi-Qun T
a
ng
1
;
2
;
Xi Li
1
;
lixi@shmu.edu.cn" cl
a
ss="
a
uth_m
a
il" title="E-m
a
il the corresp
on
ding
a
uthor
关键词：
N
A
FLD
;
n
on
-
a
lcoholic f
a
tty
liver
dise
a
se
;
ChIP
;
chrom
a
tin immunoprecipit
a
ti
on
;
HFD
;
high-f
a
t diet
;
A
LT
;
a
l
a
nine
a
minotr
a
nsfer
a
se
;
A
ST
;
a
sp
a
rt
a
te
a
minotr
a
nsfer
a
se
;
FF
A
;
free f
a
tty
a
cid
;
F
A
S
;
f
a
tty
a
cid synth
a
se
;
SCD1
;
ste
a
royl coenzyme A des
a
tur
a
se 1
;
SREBP-1C
;
sterol regul
a
tory element binding protein 1C
;
A
CC
;
a
cetyl coenzyme A c
a
rboxyl
a
se
;
PP
A
R
;
peroxisome prolifer
a
tor-
a
ctiv
a
ted receptor
;
LXRα
;
liver
X receptor
a
lph
a
;
DG
A
T
;
di
a
cylglycerol
a
cyl coenzyme A
a
cyltr
a
nsfer
a
se
;
CPT1
;
c
a
rnitine p
a
lmito
刊名：Journ
a
l of Hep
a
tology
出版年：2015
1
2
3
4
5
6
7
8
9
按检索点细分(257)
题名(12)
关键词(22)
文摘(155)
按出版年细分(257)
2027年及以后(17)
2017年(3)
2016年(17)
2015年(13)
2014年(1)
2013年(29)
2012年(21)
2011年(16)
2010年(18)
2009年(16)
2008年(14)
2007年(21)
2006年(11)
2005年(3)
2004年(9)
2003年(13)
2002年(4)
2001年(3)
2000年(1)
2000年及以前(27)
NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via
email
.
