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Springer电子图书(1)
NATURE电子期刊(2)
ACS电子期刊(8)
SpringerLink电子期刊(4)
Elsevier电子期刊(21)
在“
Elsevier电子期刊
”中,
命中:
21
条,耗时:小于0.01 秒
在所有数据库中总计命中:
36
条
1.
Optimization of a 1,5-dihydrobenzo[b][1,4]diazepine-2,4-dione series of HIV capsid assembly inhibitors 2: Structure-activity relationships (SAR) of the C3-phenyl moiety
作者:
Lee D. Fader
;
&dagger
;
;
lee.fader@boehringer-ingelheim.com
;
Serge Landry
;
Sylvie Goulet
;
Sé
;
bastien Morin
;
Stephen H. Kawai
&Dagger
;
;
Yves Bousquet
;
Isabelle Dion
;
Oliver Hucke
;
Nathalie Goudreau
;
Christopher T. Lemke
;
Jean Rancourt
;
Pierre Bonneau
;
Steve Titolo
;
Ma&rsquo
;
an Amad
;
Michel
Garneau
;
Jianmin Duan
;
Stephen Mason
§
;
;
Bruno Simoneau
关键词:
HIV
;
Capsid Assembly Inhibitor
;
Immature Gag assembly Inhibitor
;
Benzodiazepine
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2013
2.
Anthranilic acid-based Thumb Pocket 2 HCV NS5B polymerase inhibitors with sub-micromolar potency in the cell-based replicon assay
作者:
Timothy A. Stammers
;
Ren茅 Coulombe
;
Martin Duplessis
;
Gulrez Fazal
;
Alex
;
re Gagnon
;
Michel
Garneau
;
Sylvie Goulet
;
Araz Jakalian
;
Steven LaPlante
;
Jean Rancourt
;
Bounkham Thavonekham
;
Dominik Wernic
;
George Kukolj
;
Pierre L. Beaulieu
关键词:
HCV NS5B polymerase
;
Thumb Pocket 2
;
Non-nucleoside inhibitor
;
Structure-based drug design
;
Direct-acting antiviral
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:15 December, 2013
3.
Synthesis and optimization of a novel series of HCV NS3 protease inhibitors: 4-Arylproline analogs
作者:
Fran?ois Bilodeau
;
Murray D. Bailey
;
Punit K. Bhardwaj
;
Jos¨¦e Bordeleau
;
Pat Forgione
;
Michel
Garneau
;
Elise Ghiro
;
Vida Gorys
;
Ted Halmos
;
Eric S. Jolicoeur
;
M¨¦lissa Leblanc
;
Christopher T. Lemke
;
Julie Naud
;
Jeff O¡¯Meara
;
Peter W. White
;
Montse Llin¨¤s-Brunet
关键词:
HCV
;
NS3 protease inhibitors
;
Peptidomimetic inhibitors
;
Grignard&ndash
;
Knochel reagents
;
4-Biphenyl-proline
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2013
4.
Peptide backbone replacement of hepatitis C virus NS3 serine protease C-terminal cleavage product analogs: Discovery of potent succinamide inhibitors
作者:
Murray D. Bailey
;
Jos¨¦e Bordeleau
;
Michel
Garneau
;
M¨¦lissa Leblanc
;
Christopher T. Lemke
;
Jeff O¡¯Meara
;
Peter W. White
;
Montse Llin¨¤s-Brunet
关键词:
Hepatitis C NS3 protease
;
Peptide backbone replacement
;
Succinamide
;
Peptidomimetic
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2013
5.
Historical records of atmospheric metal deposition along the St. Lawrence Valley (eastern Canada) based on peat bog cores
作者:
Steve Pratte
;
Alfonso Mucci
;
Michel
le
Garneau
关键词:
Trace metal pollution
;
Peat bogs
;
Industrial Revolution
;
Lead isotopes
;
Northeastern America
刊名:Atmospheric Environment
出版年:2013
6.
Holocene paleohydrological reconstruction and carbon accumulation of a permafrost peatland using testate amoeba and macrofossil analyses, Kuujjuarapik, subarctic Qu¨¦bec, Canada
作者:
Alexandre Lamarre
;
lamarrealex@hotmail.com
;
Michel
le
Garneau
Garneau.
michel
le@uqam.ca
;
Hans Asnong
asnong.hans@uqam.ca
关键词:
peatland
;
testate amoebae
;
permafrost dynamics
;
peat accumulation
;
Little Ice Age
;
Holocene
刊名:Review of Palaeobotany and Palynology
出版年:2012
7.
The Holocene carbon dynamics of boreal and subarctic peatlands of Northeastern Canada
作者:
Michel
le
Garneau
garneau
.
michel
le@uqam.ca
刊名:Quaternary International
出版年:2012
8.
Benzimidazole Thumb Pocket I finger-loop inhibitors of HCV NS5B polymerase: Improved drug-like properties through C-2 SAR in three sub-series
作者:
Pierre L. Beaulieu
;
Nathalie Dansereau
;
Jianmin Duan
;
Michel
Garneau
;
James Gillard
;
Ginette McKercher
;
Steven LaPlante
;
Lisette Lagacé
e ;
Louise Thauvette
;
George Kukolj
关键词:
Hepatitis C virus
;
HCV
;
NS5B polymerase
;
Allosteric inhibitors
;
Replicon inhibitors
;
Benzimidazole
;
Antivirals
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2010
9.
Late Holocene paleoecohydrology and carbon accumulation estimates from two boreal peat bogs in eastern Canada: Potential and limits of multi-proxy archives
作者:
Julie Loisel
;
Michel
le
Garneau
关键词:
Peat bog
;
Testate amoebae
;
Multi-proxy analysis
;
Carbon cycle
;
Late Holocene
;
Eastern Canada
刊名:Palaeogeography, Palaeoclimatology, Palaeoecology
出版年:2010
10.
N-Acetamideindolecarboxylic acid allosteric ‘finger-loop’ inhibitors of the hepatitis C virus NS5B polymerase: discovery and initial optimization studies
作者:
Pierre L. Beaulieu
;
Eric Jolicoeur
;
James Gillard
;
Christian Brochu
;
René
;
Coulombe
;
Nathalie Dansereau
;
Jianmin Duan
;
Michel
Garneau
;
Araz Jakalian
;
Peter Kü
;
hn
;
Lisette Lagacé
;
Steven L
关键词:
HCV NS5B polymerase
;
HCV replicon inhibitors
;
Allosteric inhibitors
;
Antivirals
;
Hepatitis C virus
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2010
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