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在“
Elsevier电子期刊
”中,
命中:
2,433
条,耗时:0.0699691 秒
在所有数据库中总计命中:
3,165
条
1.
A novel curcumin derivative which inhibits P-glycoprotein, arrests cell cycle and induces apoptosis in
multi
drug resistance cells
作者:
Vanessa Lopes-Rodrigues
a
;
b
;
c
;
h
;
Ana Oliveira
d
;
h
;
Marta Correia-da-Silva
d
;
e
;
Madalena Pinto
d
;
e
;
Raquel T. Lima
a
;
b
;
f
;
Emí
;
lia Sousa
d
;
e
;
esousa@ff.up.pt
;
M. Helena Vasconcelos
a
;
b
;
g
;
hvasconcelos@ipatimup.pt
关键词:
ABC
;
ATP-binding cassette
;
DMSO
;
dimethyl sulfoxide
;
EtOAc
;
ethyl acetate
;
EtOH
;
ethanol
;
FBS
;
fetal bovine serum
;
h
;
hours
;
HPLC
;
high-performance liquid chromatography
;
HRMS-ESI
;
high resolution mass spectrometry-electrospray ionization
;
MDR
;
multi
drug resistance
;
MeOH
;
methanol
;
min
;
minutes
;
mp
;
melting point
;
MW
;
microwave
;
PBS
;
phosphate buffered saline
;
P-
gp
;
P-glycoprotein
;
r.t.
;
room temperature
;
SRB
;
sulforhodamine B
;
THF
;
tetrahydrofuran
刊名:Bioorganic & Medicinal Chemistry
出版年:2017
2.
Overcoming
multi
drug resistance via simultaneous delivery of cytostatic drug and P-glycoprotein inhibitor to cancer cells by HPMA copolymer conjugate
作者:
Ladislav Sivak
a
;
Vladimir Subr
b
;
Jakub Tomala
a
;
Blanka Rihova
a
;
Jiri Strohalm
b
;
Tomas Etrych
b
;
Marek Kovar
a
;
makovar@biomed.cas.cz
关键词:
Multi
drug resistance
;
P-glycoprotein
;
Doxorubicin
;
Reversin 121
;
HPMA copolymer carrier
;
Polymer-drug conjugate
刊名:Biomaterials
出版年:2017
3.
DNA damage induced by NADPH cytochrome P450 reductase-activated idarubicin in sensitive and
multi
drug resistant MCF7 breast cancer cells
作者:
Wojciech Żwierełło
a
;
b
;
Agnieszka Maruszewska
a
;
b
;
Robert Nowak
a
;
b
;
1
;
Dorota Kostrzewa-Nowak
a
;
b
;
2
;
Jolanta Tarasiuk
a
;
b
;
tarasiuk@univ.szczecin.pl
关键词:
Anthracycline antitumour drugs
;
Idarubicin
;
NADPH cytochrome P450 reductase
;
Multi
drug resistance
;
DNA damage
刊名:Pharmacological Reports
出版年:2017
4.
MiR-129 regulates cisplatin-resistance in human gastric cancer cells by targeting P-
gp
作者:
Chaojing Lu
a
;
1
;
Zhengxiang Shan
b
;
1
;
Chunguang Li
a
;
Lixin Yang
a
;
yanglixin_76@126.com
关键词:
Multi
ple drug resistance
;
Gastric cancer
;
P-glycoprotein
;
miR-129
刊名:Biomedicine & Pharmacotherapy
出版年:2017
5.
Gamma-tocotrienol reverses
multi
drug resistance of breast cancer cells with a mechanism distinct from that of atorvastatin
作者:
Yuedi Ding
dingyuedi@jsinm.org
;
Ying Peng
;
Lili Deng
;
Jun Fan
;
Biao Huang
;
huangbiao@jsinm.org
关键词:
Atorvastatin
;
γ-tocotrienol
;
Mevalonate pathway
;
Multi
drug resistance
刊名:The Journal of Steroid Biochemistry and Molecular Biology
出版年:2017
6.
N-alkanol-N-cyclohexanol amine aryl esters:
Multi
drug resistance (MDR) reversing agents with high potency and efficacy
作者:
Elisabetta Teodori
a
;
elisabetta.teodori@unifi.it
;
Silvia Dei
a
;
Marcella Coronnello
b
;
Elisa Floriddia
a
;
Gianluca Bartolucci
a
;
Dina Manetti
a
;
Maria Novella Romanelli
a
;
Diego Santo Domingo Porqueras
c
;
Milena Salerno
c
关键词:
MDR reversers
;
P-
gp
modulators
;
N-alkanol-N-cyclohexanol amine aryl esters
;
Chemosensitizers
;
Doxorubicin-resistant human erythroleukemia K562 cells (K562/DOX)
;
Pirarubicin uptake
刊名:European Journal of Medicinal Chemistry
出版年:2017
7.
Evading P-glycoprotein mediated-efflux chemoresistance using Solid Lipid Nanoparticles
作者:
Marco C. Cavaco
b
;
1
;
Carolina Pereira
a
;
1
;
Bruna Kreutzer
b
;
Luis F. Gouveia
a
;
Beatriz Silva-Lima
b
;
Alexandra M. Brito
c
;
Mafalda Videira
a
;
mafaldavideira@campus.ul.pt
关键词:
ALDH1
;
aldehyde dehydrogenase 1
;
bp
;
base pairs
;
CME
;
clathrin-mediated endocytosis
;
CSC
;
cancer stem cells
;
ECM
;
extracellular matrix
;
EMT
;
epithelial-mesenchymal transition
;
HA
;
hyaluronic acid
;
MDR
;
multi
drug resistance
;
PEG-PE
;
polyethylene glycol-phosphatidylethanolamine
;
P-
gp
;
P-glycoprotein
;
Ptx
;
paclitaxel
;
SLN
;
solid lipid nanoparticles
;
SC
;
stem cells
;
TNBC
;
triple negative breast cancer
刊名:European Journal of Pharmaceutics and Biopharmaceutics
出版年:2017
8.
Co-delivery of
multi
ple drug resistance inhibitors by polymer/inorganic hybrid nanoparticles to effectively reverse cancer drug resistance
作者:
Cong Wu
1
;
Meng-Qing Gong
1
;
Bo-Ya Liu
;
Ren-Xi Zhuo
;
Si-Xue Cheng
;
chengsixue@whu.edu.cn
;
chengsixue@hotmail.com
关键词:
Hybrid nanoparticles
;
Multi
ple drug resistance
;
Drug resistance inhibitor
;
Co-delivery
;
Immunostimulatory effects
刊名:Colloids and Surfaces B: Biointerfaces
出版年:2017
9.
A
multi
-endpoint matched molecular pair (MMP) analysis of 6-membered heterocycles
作者:
George Chang
a
;
george.c.chang@pfizer.com
;
Kim Huard
b
;
Gregory W. Kauffman
a
;
Antonia F. Stepan
c
;
Christopher E. Keefer
a
关键词:
Matched molecular pair
;
Multi
parameter optimization
;
Log
;
D lipophilicity
;
Human liver microsomal metabolism
;
P-
gp
efflux
;
Passive membrane permeability
刊名:Bioorganic & Medicinal Chemistry
出版年:2017
10.
EBI2 Is Highly Expressed in
Multi
ple Sclerosis Lesions and Promotes Early CNS Migration of Encephalitogenic CD4 T Cells
作者:
Florian Wanke
1
;
Sonja Moos
1
;
Andrew L. Croxford
1
;
André
;
P. Heinen
1
;
Stephanie Grä
;
f
1
;
Bettina Kalt
1
;
Denise Tischner
2
;
Juan Zhang
3
;
Isabelle Christen
3
;
Julia Bruttger
1
;
Nir Yogev
1
;
Yilang Tang
1
;
Morad Zayoud
1
;
Nicole Israel
1
;
Khalad Karram
1
;
Sonja Reiß
;
ig
1
;
Sonja M. Lacher
1
;
Christian Reichhold
1
;
Ilgiz A. Mufazalov
1
;
Avraham Ben-Nun
4
;
Tanja Kuhlmann
5
;
Nina Wettschureck
2
;
Andreas W. Sailer
6
;
Klaus Rajewsky
7
;
Stefano Casola
8
;
stefano.casola@ifom.eu
;
Ari Waisman
1
;
waisman@uni-mainz.de
;
Florian C. Kurschus
1
;
9
;
kurschus@uni-mainz.de
关键词:
EBI2
;
GP
R183
;
7α
;
25-OHC
;
oxysterol
;
CH25H
;
Th17
;
EAE
;
CNS
;
multi
ple sclerosis
;
microglia
刊名:Cell Reports
出版年:2017
1
2
3
4
5
6
7
8
9
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题名(69)
关键词(247)
文摘(1841)
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