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Wiley电子期刊(7)
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Elsevier电子期刊(1392)
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NATURE电子期刊(4)
ACS电子期刊(78)
在“
Elsevier电子期刊
”中,
命中:
1,392
条,耗时:0.0419863 秒
在所有数据库中总计命中:
1,746
条
1.
Multi-target-directed therapeutic potential of 7-methoxytacrine-adamantylamine heterodimers in the Alzheimer's disease treatment
作者:
Zuzana Gazova
a
;
gazova@saske.sk
;
Ondrej Soukup
b
;
c
;
d
;
Vendula Sepsova
b
;
c
;
Katarina Siposova
a
;
Lucie Drtinova
c
;
Petr Jost
b
;
c
;
Katarina Spilovska
b
;
c
;
d
;
Jan Korabecny
b
;
c
;
d
;
Eugenie Nepovimova
b
;
c
;
Diana Fedunova
a
;
Martin Horak
e
;
Martina Kaniakova
e
;
Ze-Jun Wang
f
;
Ayman K. Hamouda
f
;
Kamil Kuca
b
;
c
;
d
关键词:
Amyloid
;
Aggregation
;
Aβ peptide
;
Muscarinic/
nicotinic
acetylcholine
receptor
antagonist
;
N-Methyl-d-aspartate
receptor
antagonist
;
β-Secretase inhibitor
;
Alzheimer's disease
刊名:Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
出版年:2017
2.
From pyrrolidinyl-benzodioxane to pyrrolidinyl-pyridodioxanes, or from unselective antagonism to selective partial agonism at α4β2
nicotinic
acetylcholine
receptor
作者:
Cristiano Bolchi
a
;
Francesco Bavo
a
;
Cecilia Gotti
b
;
Laura Fumagalli
a
;
Francesca Fasoli
b
;
Matteo Binda
a
;
Vanessa Mucchietto
b
;
Miriam Sciaccaluga
c
;
Simona Plutino
d
;
Sergio Fucile
c
;
d
;
Marco Pallavicini
a
;
marco.pallavicini@unimi.it
关键词:
α4β2 nAChR
;
α3β4 nAChR
;
Benzodioxane
;
Pyridodioxane
;
Partial agonism
;
Antagonism
刊名:European Journal of Medicinal Chemistry
出版年:2017
3.
Spasmogenic and spasmolytic activities of Agastache mexicana ssp. mexicana and A. mexicana ssp. xolocotziana methanolic extracts on the guinea pig ileum
作者:
Rosa Ventura-Martí
;
nez
a
;
rventuram7@hotmail.com
;
Rodolfo Rodrí
;
guez
a
;
rodcar@unam.mx
;
Marí
;
a Eva Gonzá
;
lez-Trujano
b
;
evag@imp.edu.mx
;
Guadalupe E. Á
;
ngeles-Ló
;
pez
a
;
geangeles@yahoo.com.mx
;
Myrna Dé
;
ciga-Campos
c
;
myrnadeciga@hotmail.com
;
Claudia Gó
;
mez
a
;
goac@unam.mx
关键词:
AMM
;
Agastache mexicana ssp. mexicana
;
AMX
;
Agastache mexicana ssp. xolocotziana
;
ACh
;
acetylcholine
;
KCl
;
potassium chloride
;
EFS
;
electrical field stimulation
;
CRC
;
concentration-response curve
;
Emax
;
Maximal effect
;
AUC
;
area under the curve
刊名:Journal of Ethnopharmacology
出版年:2017
4.
The kynurenine pathway in schizophrenia and bipolar disorder
作者:
Sophie Erhardt
;
sophie.erhardt@ki.se
;
Lilly Schwieler
;
Sophie Imbeault
;
Gö
;
ran Engberg
关键词:
Kynurenic acid
;
Psychosis
;
Bipolar disorder
;
Cytokines
;
KMO
;
KAT II
;
IL-1b
刊名:Neuropharmacology
出版年:2017
5.
Antagonist
pharmacology of desensitizing and non-desensitizing
nicotinic
acetylcholine
receptor
s in cockroach neurons
作者:
Vincent L. Salgado
vincent.salgado@basf.com" class="auth_mail" title="E-mail the corresponding author
vincesalgado@gmail.com" class="auth_mail" title="E-mail the corresponding author
关键词:
Nicotinic
acetylcholine
receptor
antagonist
;
American cockroach
;
Dihydro-β-erythroidine (DHBE)
;
d-Tubocurarine
;
Condelphine
;
Phencyclidine
;
Mecamylamine
刊名:Neurotoxicology
出版年:2016
6.
Emamectin is a non-selective allosteric activator of
nicotinic
acetylcholine
receptor
s and GABA
A/C
receptor
s
作者:
Xiaojun Xu
a
;
b
;
Caraline Sepich
c
;
Ronald J. Lukas
b
;
Guonian Zhu
a
;
Yongchang Chang
b
;
Yongchang.chang@dignityhealth.org" class="auth_mail" title="E-mail the corresponding author
关键词:
Emamectin
;
Ivermectin
;
Nicotinic
receptor
;
GABAA/C
receptor
;
Allosteric activation
刊名:Biochemical and Biophysical Research Communications
出版年:2016
7.
Molecular simulation study of the unbinding of α-conotoxin [ϒ4E]GID at the α7 and α4β2 neuronal
nicotinic
acetylcholine
receptor
s
作者:
Abishek Suresh
1
;
Andrew Hung
;
1
;
andrew.hung@rmit.edu.au
关键词:
Conotoxins
;
Nicotinic
acetylcholine
receptor
s
;
Molecular-dynamics simulations
;
Binding-free energy
;
Antagonist
;
Umbrella-sampling
刊名:Journal of Molecular Graphics and Modelling
出版年:2016
8.
Dissection of N,N-diethyl-N′-phenylpiperazines as α7
nicotinic
receptor
silent agonists
作者:
Marta Quadri
a
;
&dagger
;
;
Roger L. Papke
b
;
Nicole A. Horenstein
a
;
horen@chem.ufl.edu" class="auth_mail" title="E-mail the corresponding author
关键词:
ACh
;
acetylcholine
;
AcOH
;
acetic acid
;
DiEPP
;
N
;
N-diethyl-N&prime
;
-phenylpiperazinium
;
DiMPP
;
N
;
N-dimethyl-N&prime
;
-phenylpiperazinium
;
PAM
;
positive allosteric modulator
;
PEP
;
N-phenyl-N&prime
;
ethylpiperazine
;
nAChR
;
nicotinic
acetylcholine
receptor
;
TFAA
;
trifluoroacetic anhydride
;
THF
;
tetrahydrofuran
刊名:Bioorganic & Medicinal Chemistry
出版年:2016
9.
Mode of action of triflumezopyrim: A novel mesoionic insecticide which inhibits the
nicotinic
acetylcholine
receptor
作者:
Daniel Cordova
a
;
daniel.cordova@usa.dupont.com" class="auth_mail" title="E-mail the corresponding author
;
Eric A. Benner
a
;
Mark E. Schroeder
b
;
Caleb W. Holyoke Jr.
a
;
Wenming Zhang
a
;
Thomas F. Pahutski
a
;
Robert M. Leighty
a
;
Daniel R. Vincent
a
;
Jason C. Hamm
a
关键词:
Nicotinic
acetylcholine
receptor
;
Mesoionic
;
Inhibitor
;
Antagonist
;
Desensitization
;
Periplaneta americana
;
Nilaparvata lugens
;
Myzus persicae
刊名:Insect Biochemistry and Molecular Biology
出版年:2016
10.
Nicotinic
receptor
involvement in regulation of functions of mouse neutrophils from inflammatory site
作者:
Valentina G. Safronova
a
;
safronova@icb.psn.ru" class="auth_mail" title="E-mail the corresponding author
;
Catherine A. Vulfius
a
;
Irina V. Shelukhina
b
;
Valentina N. Mal&rsquo
;
tseva
a
;
Alexey V. Berezhnov
a
;
Eugeniya I. Fedotova
a
;
Regina G. Miftahova
a
;
c
;
Elena V. Kryukova
b
;
Andrey A. Grinevich
a
;
Victor I. Tsetlin
b
关键词:
ACh
;
acetylcholine
;
BSA
;
bovine serum albumin
;
αBgt
;
α-bungarotoxin
;
[Ca2+]i
;
intracellular free Ca2+ concentration
;
αCTX
;
α-cobratoxin
;
fMLF
;
N-formyl-l-methionyl-l-leucyl-l-phenylalanine
;
HBSS
;
Hanks&rsquo
;
balanced salt solution
;
IL-8
;
interleukin-8
;
LPS
;
lipopolysaccharide
;
MIP-2
;
macrophage inhibiting protein-2
;
MMP-9
;
matrix metallopeptidase-9
;
nAChR
;
nicotinic
acetylcholine
receptor
;
NF-kB
;
nuclear factor-kB
;
PKC
;
protein kinase C
;
PMSF
;
phenylmethylsulfonyl fluoride
;
PMN
;
polymorphonucle
刊名:Immunobiology
出版年:2016
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