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Elsevier电子期刊(17)
在“
Elsevier电子期刊
”中,
命中:
17
条,耗时:小于0.01 秒
在所有数据库中总计命中:
17
条
1.
Design, synthesis, structure-activity relationship and mechanism of action studies of a series of 4-chloro-1-phthalazinyl hydrazones as a potent agent against Leishmania braziliensis
作者:
Angel H. Romero
a
;
angel.romero12@ucv.ve
;
Rafael Medina
b
;
Anamarí
;
a Alcala
c
;
Yael Garcí
;
a-Marchan
c
;
Jorge Nú
;
ñ
;
ez-Duran
c
;
Jacques Leañ
;
ez
c
;
Ali Mijoba
c
;
Carlos Ciangherotti
d
;
Xenó
;
n Serrano-Martí
;
n
c
;
Simó
;
n E. Ló
;
pez
a
;
slopez@usb.ve
关键词:
Leishmania braziliensis
;
Antileishmanial activity
;
Superoxide dismutase
;
Promastigotes
;
Phthalazine
;
Nitroheterocycle
刊名:European Journal of Medicinal Chemistry
出版年:2017
2.
Rational design of nitrofuran derivatives: Synthesis and valuation as inhibitors of Trypanosoma cruzi trypanothione reductase
作者:
D.G. Arias
a
;
b
;
F.E. Herrera
b
;
A.S. Garay
b
;
D. Rodrigues
b
;
P.S. Forastieri
c
;
L.E. Luna
c
;
M.D.L.M. Bü
;
rgi
b
;
C. Prieto
b
;
A.A. Iglesias
a
;
b
;
R.M. Cravero
c
;
S.A. Guerrero
a
;
d
;
saguerrero@santafe-conicet.gov.ar
关键词:
Trypanosoma cruzi
;
Trypanothione
;
Nitroheterocycle
drugs
;
Nifurtimox
刊名:European Journal of Medicinal Chemistry
出版年:2017
3.
Antichagasic and trichomonacidal activity of 1-substituted 2-benzyl-5-nitroindazolin-3-ones and 3-alkoxy-2-benzyl-5-nitro-2H-indazoles
作者:
Cristina Fonseca-Berzal
a
;
b
;
Alexandra Ibá
;
ñ
;
ez-Escribano
a
;
b
;
Felipe Reviriego
a
;
c
;
José
;
Cumella
c
;
Paula Morales
c
;
Nadine Jagerovic
c
;
Juan José
;
Nogal-Ruiz
a
;
b
;
José
;
Antonio Escario
a
;
b
;
Patricia Bernardino da Silva
d
;
Maria de Nazaré
;
C. Soeiro
d
;
Alicia Gó
;
mez-Barrio
a
;
b
;
agbarrio@ucm.es" class="auth_mail" title="E-mail the corresponding author
;
Vicente J. Ará
;
n
a
;
c
;
vjaran@iqm.csic.es" class="auth_mail" title="E-mail the corresponding author
关键词:
Antiprotozoal drug
;
Nitroheterocycle
;
Indazole
;
Trichomonas vaginalis
;
Trypanosoma cruzi
刊名:European Journal of Medicinal Chemistry
出版年:2016
4.
Discovery of
nitroheterocycle
s active against African trypanosomes. In vitro screening and preliminary SAR studies
作者:
Vicente J. Ar¨¢n
;
Marcel Kaiser
;
Christophe Dardonville
关键词:
CNS
;
central nervous system
;
DNDi
;
Drugs for Neglected Diseases initiative
;
HAT
;
human African trypanosomiasis
;
IC50
;
50 % inhibitory concentration
;
MEM
;
minimum essential medium
;
NECT
;
nifurtimox&ndash
;
eflornithine combination therapy
;
NTD
;
neglected trop
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2012
5.
Further evidence of the trypanocidal action of eupomatenoid-5: Confirmation of involvement of reactive oxygen species and mitochondria owing to a reduction in trypanothione reductase activity
作者:
D. Lazarin-Bidó
;
ia
a
;
V.C. Desoti
a
;
T. Ueda-Nakamura
a
;
b
;
B.P. Dias Filho
a
;
b
;
C.V. Nakamura
a
;
b
;
S.O. Silva
a
;
b
;
lautenschlager@uem.br
关键词:
Trypanosoma cruzi
;
Eupomatenoid-5
;
Trypanothione reductase
;
ROS
;
Mitochondria
;
Cell death
;
Free radicals
刊名:Free Radical Biology and Medicine
出版年:2013
6.
Voltammetry of nitrobenzene with cysteine and other acids in DMSO. Implications for the biological reactivity of reduced nitroaromatics with thiols
作者:
Theresa Andres
a
;
Lars Eckmann
b
;
Diane K. Smith
a
;
dsmith@sciences.sdsu.edu
关键词:
Organic electrochemistry
;
Cyclic voltammetry
;
Nitrobenzene
;
Thiol
;
Semi-mercaptal
刊名:Electrochimica Acta
出版年:2013
7.
ESR, electrochemical, molecular modeling and biological evaluation of 4-substituted and 1,4-disubstituted 7-nitroquinoxalin-2-ones as potential anti-Trypanosoma cruzi agents
作者:
Benjamí
;
n Aguilera-Venegas
a
;
Claudio Olea-Azar
a
;
colea@uchile.cl
;
Ester Norambuena
b
;
Vicente J. Ará
;
n
c
;
Fernando Mendizá
;
bal
d
;
Michel Lapier
a
;
Juan Diego Maya
e
;
Ulrike Kemmerling
e
;
Rodrigo Ló
;
pez-Muñ
;
oz
e
关键词:
Nitroquinoxaline
;
Chagas’
;
disease
;
ESR
;
Trypomastigote
;
Epimastigote
;
Molecular Modeling
刊名:Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
出版年:2011
8.
Microwave-assisted reactions of
nitroheterocycle
s with dienes. Diels–Alder and tandem hetero Diels–Alder/[3,3] sigmatropic shift
作者:
M. Victoria Gó
;
mez
;
Ana I. Ar
a ;
André
;
s Moreno
;
Fern
;
o P. Cossí
o ;
Abel de Có
;
zar
;
Á
;
ngel Dí
;
az-Ortiz
;
Antonio de la Hoz
;
Pilar Prieto
关键词:
Microwave irradiation
;
Diels–
;
Alder
;
Diels–
;
Alder/[3
;
3] sigmatropic shift
;
Computational studies
刊名:Tetrahedron
出版年:2009
9.
Nitroreductive metabolic activation of some carcinogenic nitro heterocyclic food contaminants in rat mammary tissue cellular fractions
作者:
L.C. Bartel
;
M. Montalto de Mecca
;
J.A. Castro
关键词:
Nitrofurans
;
Nitroimidazoles
;
Carcinogenicity
;
Mammary tissue
;
Xanthine-oxidoreductase
刊名:Food and Chemical Toxicology
出版年:2009
10.
The effects on Trypanosoma cruzi
作者:
Rubem F.S. Menna-Barreto
;
Renata L.S. Goncalves
;
Elaine M. Costa
;
Raphael S.F. Silva
;
Antonio V. Pinto
;
Marcus F. Oliveira
;
Solange L. de Castro
关键词:
Trypanosoma cruzi
;
Chagas disease
;
Chemotherapy
;
Naphthoquinones
;
Reactive oxygen species
;
Superoxide
;
Metabolism
;
Free radicals
刊名:Free Radical Biology and Medicine
出版年:2009
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