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在“
Elsevier电子期刊
”中,
命中:
740
条,耗时:0.0259862 秒
在所有数据库中总计命中:
1,153
条
1.
Mitochondrial defects arise from
nucleoside
/nucleotide
reverse
transcriptase
inhibitors
in neurons: Potential contribution to HIV-associated neurocognitive disorders
作者:
Kui-Ming Hung
a
;
b
;
Pei-Chun Chen
b
;
Han-Chieh Hsieh
c
;
Marcus J Calkins
a
;
mjcalkins@mail.ncku.edu.tw
关键词:
NRTI
;
nucleoside
/nucleotide
reverse
transcriptase
inhibitor
;
HAND
;
HIV-associated neurocognitive disorders
;
cART
;
combination antiretroviral therapy
;
pol γ
;
polymerase γ
;
mtDNA
;
mitochondrial DNA
;
ddI
;
didanosine
;
AZT
;
zidovudine
;
FTC
;
emtricitabine
;
TDF
;
tenofovir
;
ddC
;
zalcitabine
;
d4T
;
stavudine
;
3TC
;
lamivudine
;
ABC
;
abacavir
;
PGC-1α
;
peroxisome proliferator-activated receptor γ coactivator 1α
;
mtUPR
;
mitochondrial unfolded protein response
;
CO1
;
Cytochrome oxidase I
;
ND1
;
NADH Dehydrogenase
刊名:Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
出版年:2017
2.
Body composition and metabolic outcomes after 96 weeks of treatment with ritonavir-boosted lopinavir plus either
nucleoside
or nucleotide
reverse
transcriptase
inhibitors
or raltegravir in patients with HIV with virological failure of a standard first-line antiretroviral therapy regimen: a substudy of the randomised, open-label,
non
-inferiority SEC
作者:
Prof Mark A Boyd
;
MD
a
;
b
;
mark.boyd@adelaide.edu.au
;
Janaki Amin
;
PhD
b
;
Patrick W G Mallon
;
PhD
c
;
Nagalingeswaran Kumarasamy
;
MD
d
;
Johan Lombaard
;
MD
e
;
Prof Robin Wood
;
PhD
f
;
Prof Ploenchan Chetchotisakd
;
MD
g
;
Prof Praphan Phanuphak
;
PhD
h
;
Lerato Mohapi
;
MD
i
;
Iskandar Azwa
;
MD
j
;
Waldo H Belloso
;
MD
k
;
Prof Jean-Michel Molina
;
PhD
l
;
Prof Jennifer Hoy
;
MD
m
;
Cecilia L Moore
;
MIPH
b
;
Prof Sean Emery
;
PhD
b
;
Prof David A Cooper
;
FAA
b
;
on behalf of the SECOND-LINE Study Group
&dagger
;
刊名:The Lancet HIV
出版年:2017
3.
Efavirenz dissolution enhancement III: Colloid milling, pharmacokinetics and electronic tongue evaluation
作者:
Cristiane R.D. Hoffmeister
a
;
Cinira Fandaruff
b
;
Maí
;
ra A. da Costa
a
;
Lucio M. Cabral
c
;
Luciana R. Pitta
d
;
Stanley E.R. Bilatto
e
;
f
;
Livia D. Prado
a
;
Daniel S. Corrê
;
a
e
;
f
;
Leandro Tasso
g
;
Marcos Antô
;
nio S. Silva
b
;
Helvé
;
cio V.A. Rocha
a
;
c
;
helveciorocha@far.fiocruz.br
关键词:
EFV
;
efavirenz
;
NNRTI
;
non
-
nucleoside
reverse
transcriptase
inhibitor
;
HIV-1/AIDS
;
human immunodeficiency virus type 1 infection
;
SLS
;
sodium lauryl sulfate
;
HPC
;
hydroxypropylcellulose
;
HPMC
;
hydroxypropylmetilcellulose
;
NRTIs
;
nucleoside
reverse
transcriptase
inhibitors
;
API
;
active pharmaceutical ingredient
;
CD
;
cyclodextrin
;
FDA
;
Food and Drug Administration
;
AUC
;
area under the curve
刊名:European Journal of Pharmaceutical Sciences
出版年:2017
4.
Identifications of drug resistance mutations among antiretroviral treatment naive HIV-1 patients in Peninsular Malaysia
作者:
Rozainanee Mohd Zain
;
rozainanee@yahoo.com
;
Nabila Ibrahim
;
Suriani Ismail
;
Jeyanthi Suppiah
;
Nor Aziyah Mat Rahim
;
Ravindran Thayan
关键词:
HIV
;
Resistance
;
Malaysia
;
Antiretroviral treatment naive
刊名:Asian Pacific Journal of Tropical Medicine
出版年:2017
5.
Systematic evaluation of methyl ester bioisosteres in the context of developing alkenyldiarylmethanes (ADAMs) as
non
-
nucleoside
reverse
transcriptase
inhibitors
(NNRTIs) for anti-HIV-1 chemotherapy
作者:
Ayako Hoshi
a
;
Takeshi Sakamoto
a
;
sakamoto@josai.ac.jp" class="auth_mail" title="E-mail the corresponding author
;
Jun Takayama
a
;
Meiyan Xuan
a
;
Mari Okazaki
a
;
Tracy L. Hartman
b
;
Robert W. Buckheit Jr.
b
;
Christophe Pannecouque
c
;
Mark Cushman
d
;
cushman@purdue.edu" class="auth_mail" title="E-mail the corresponding author
关键词:
ADAM
;
alkenyldiarylmethane
;
NNRTI
;
non
-
nucleoside
reverse
transcriptase
inhibitor
;
RT
;
reverse
transcriptase
;
HIV-1
;
human immunodeficiency virus type 1
;
AIDS
;
acquired immune deficiency syndrome
;
ART
;
antiretroviral therapy
;
NRTI
;
nucleoside
reverse
transcriptase
inhibitor
;
PI
;
protease inhibitor
;
INI
;
integrase
inhibitors
;
FI
;
fusion inhibitor
;
CCR5I
;
CC chemokine receptor inhibitor
;
dNTPs
;
deoxy
nucleoside
triphosphate
;
AZT
;
azidothymidine (zidovudine)
;
EDCI
;
1-(3-dimethylaminopropyl)-3-ethylc
刊名:Bioorganic & Medicinal Chemistry
出版年:2016
6.
Hydrophobic-core PEGylated graft copolymer-stabilized nanoparticles composed of insoluble
non
-
nucleoside
reverse
transcriptase
inhibitors
exhibit strong anti-HIV activity
作者:
Anita Leporati
a
;
Mikhail S. Novikov
b
;
Vladimir T. Valuev-Elliston
c
;
Sergey P. Korolev
d
;
Anastasia L. Khandazhinskaya
c
;
Sergey N. Kochetkov
c
;
Suresh Gupta
a
;
Julian Goding
a
;
Elijah Bolotin
e
;
Marina B. Gottikh
d
;
Alexei A. Bogdanov Jr.
a
;
Alexei.Bogdanov@umassmed.edu" class="auth_mail" title="E-mail the corresponding author
关键词:
Non
-
nucleoside
reverse
transcriptase
inhibitors
;
Microbicide
;
HIV-1
;
Nanoparticle
;
Copolymer
;
Benzophe
non
e-uracyl
刊名:Nanomedicine: Nanotechnology, Biology and Medicine
出版年:2016
7.
Advances in rationally designed dual
inhibitors
of HIV-1
reverse
transcriptase
and integrase
作者:
Shuang-Xi Gu
a
;
shuangxigu@163.com" class="auth_mail" title="E-mail the corresponding author
;
Ping Xue
a
;
Xiu-Lian Ju
a
;
Yuan-Yuan Zhu
b
;
yyzhu531@163.com" class="auth_mail" title="E-mail the corresponding author
关键词:
HIV
;
AIDS
;
Reverse
transcriptase
;
Integrase
;
Rational drug design
;
Dual
inhibitors
刊名:Bioorganic & Medicinal Chemistry
出版年:2016
8.
An in-silico approach aimed to clarify the role of Y181C and K103N HIV-1
reverse
transcriptase
mutations versus Indole Aryl Sulphones
作者:
Alberto Massarotti
a
;
1
;
Antonio Coluccia
b
;
1
;
antonio.coluccia@uniroma1.it" class="auth_mail" title="E-mail the corresponding author
关键词:
Non
nucleoside
reverse
transcriptase
inhibitors
;
Drug resistant
reverse
transcriptase
;
Molecular dynamics
刊名:Journal of Molecular Graphics and Modelling
出版年:2016
9.
Discovery, characterization, and lead optimization of 7-azaindole
non
-
nucleoside
HIV-1
reverse
transcriptase
inhibitors
作者:
Richard A. Stanton
a
;
Xiao Lu
a
;
Mervi Detorio
a
;
Catherine Montero
a
;
Emily T. Hammond
a
;
Maryam Ehteshami
a
;
Robert A. Domaoal
a
;
James H. Nettles
a
;
Michel Feraud
b
;
Raymond F. Schinazi
a
;
rschina@emory.edu" class="auth_mail" title="E-mail the corresponding author
关键词:
HIV
;
Reverse
transcriptase
;
NNRTI
;
FEP
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2016
10.
Anti-HIV cytotoxicity enzyme inhibition and molecular docking studies of quinoline based chalcones as potential
non
-
nucleoside
reverse
transcriptase
inhibitors
(NNRT)
作者:
Asima Hameed
a
;
Muhammad Imran Abdullah
a
;
imranchemist.ali@gmail.com" class="auth_mail" title="E-mail the corresponding author
;
Ejaz Ahmed
a
;
dr.ejaz.ahmed@gmail.com" class="auth_mail" title="E-mail the corresponding author
;
Ahsan Sharif
a
;
Ahmad Irfan
b
;
c
;
Sara Masood
d
关键词:
VGIADQMPNCXBHL-VQHVLOKHSA-N
;
KCIUTVFYGJMWTC-SOFGYWHQSA-N
;
ZPLWBJGDXRDLNB-WEVVVXLNSA-N
;
CBWJFBGDNVYLJE-XBXARRHUSA-N
;
GBVFUHANOGHFBF-WEVVVXLNSA-N
;
YGFONNIITAZYLE-UXBLZVDNSA-N
;
ZGGWEUHTNVNGOL-HWKANZROSA-N
;
PPAKHLQEOXETKT-HWKANZROSA-N
;
WODVNQKBWBZTIJ-HWKANZROSA-N
;
ZJFDWXBUYWWPPT-FNORWQNLSA-N
;
XTWBDIMTWLWPKM-GQCTYLIASA-N
;
RFBVFEIQNRHFAR-FNORWQNLSA-N
;
JZTJMCRSYPGCOI-ZZXKWVIFSA-N
;
DSAWMPZECFYFHV-VMPITWQZSA-N
刊名:Bioorganic Chemistry
出版年:2016
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