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Wiley电子期刊(1)
SpringerLink电子期刊(35)
Elsevier电子期刊(140)
ACS电子期刊(28)
在“
Elsevier电子期刊
”中,
命中:
140
条,耗时:小于0.01 秒
在所有数据库中总计命中:
204
条
1.
Bivalent SIRT
1
inhibitors
作者:
Juan Wang
1
;
Wenwen Zang
1
;
Jiajia Liu
1
;
Weiping Zheng
;
wzheng@ujs.edu.cn
关键词:
β-NAD+
;
β-nicotinamide adenine dinucleotide
;
NAM
;
nicotinamide
;
2&prime
;
-O-AADPR
;
2&prime
;
-O-ac
yl
-ADP-ribose
;
RP-HPLC
;
reversed-phase high performance liquid chromatography
;
HRMS
;
high-resolution mass spectrometry
;
EDC-MeI
;
1
-(3-dimeth
yl
aminoprop
yl
)-3-eth
yl
carbodiimide methiodide
;
DIC
;
N
;
N&prime
;
-diisoprop
yl
carbodiimide
;
HBTU
;
2-(
1
H-
benzotriazol
e-
1
-
yl
)-
1
13 ;
3-tetrameth
yl
aminium hexafluorophosphate
;
HOBt
;
N-hydroxy
benzotriazol
e
;
NMM
;
N-meth
yl
morpholine
;
EDC-HCl
;
1
-(3-dimeth
yl
aminoprop
yl
)-3-eth
yl
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:20
1
7
2.
1
-Heteroar
yl
propan-2-ones as inhibitors of fatty acid amide hydrolase: Studies on structure-activity relationships and metabolic stability
作者:
Stefan Zahov
;
David Garzinsky
;
Walburga Hanekamp
;
Matthias Lehr
;
lehrm@uni-muenster.de
关键词:
Propan-2-one
;
Fatty acid amide hydrolase
;
Enzyme inhibition
;
Metabolic stability
;
Aqueous solubility
刊名:Bioorganic & Medicinal Chemistry
出版年:20
1
7
3.
Opinion of the Scientific Committee on consumer safety (SCCS) - Opinion on the use of 2,2‿meth
yl
ene-bis-(6-(2H-
benzotriazol
-2-
yl
)-4-(
1
,
1
,3,3-tetrameth
yl
but
yl
)phenol) (nano) - S79 - In cosmetic products
作者:
Scientific Committee of Consumer Safety
;
;
SANTE-C2-SCCS@ec.europa.eu" class="auth_mail" title="E-mail the corresponding author
关键词:
SCCS
;
Scientific opinion
;
UV-Filter
;
S79
;
2
;
2&prime
;
-meth
yl
ene-bis-(6-(2H-
benzotriazol
-2-
yl
)-4-(
1
13 ;
3-tetrameth
yl
but
yl
)phenol) nano
;
MBBT
;
Regulation
1
223/2009
;
CAS
1
03597-45-
1
;
EC 403-800-
1
刊名:Regulatory Toxicology and Pharmacology
出版年:20
1
6
4.
Metal-free, zinc(II) and lead(II) phthalocyanines functioning with 3-(2H-benzo[d][
1
,2,3]triazol-2-
yl
)-4-hydroxypheneth
yl
methacr
yl
ate groups: Synthesis and investigation of photophysical and photochemical properties
作者:
Ü
;
mit Demirbaş
a
;
Mehmet Pişkin
b
;
Burak Barut
c
;
Rıza Bayrak
d
;
Mahmut Durmuş
e
;
Halit Kantekin
a
;
halit@ktu.edu.tr" class="auth_mail" title="E-mail the corresponding author
关键词:
Phthalocyanine
;
Benzotriazol
e
;
Photosensitizer
;
Photophysical
;
Photochemical
刊名:Synthetic Metals
出版年:20
1
6
5.
Synthesis and antibacterial evaluation of novel 4″-glyc
yl
linked quinol
yl
-azithromycins with potent activity against macrolide-resistant pathogens
作者:
Dražen Pavlović
;
dpavlovic@hotmail.fr" class="auth_mail" title="E-mail the corresponding author
;
Stjepan Mutak
关键词:
MLSB
;
macrolide&ndash
;
lincosamide&ndash
;
streptogramin B antibiotics
;
HBTU
;
O-(
benzotriazol
-
1
-
yl
)-N
N ;
N&prime
;
N&prime
;
-tetrameth
yl
uronium hexafluorophosphate
;
DIPEA
;
diisoprop
yl
eth
yl
amine
;
SAR
;
structure&ndash
;
activity relationships
刊名:Bioorganic & Medicinal Chemistry
出版年:20
1
6
6.
Quinazolines and quinazolinones as ubiquitous structural fragments in medicinal chemistry: An update on the development of synthetic methods and pharmacological diversification
作者:
Imtiaz Khan
a
;
ikhanqau@gmail.com" class="auth_mail" title="E-mail the corresponding author
;
Sumera Zaib
b
;
c
;
Sadaf Batool
d
;
Naeem Abbas
a
;
Zaman Ashraf
e
;
Jamshed Iqbal
c
;
Aamer Saeed
a
;
aamersaeed@yahoo.com" class="auth_mail" title="E-mail the corresponding author
关键词:
BPO
;
Benzotriazol
e-
1
-
yl
-oxy-tris-(dimeth
yl
amino)-phosphonium hexafluorophosphate
;
BSA
;
bovine serum albumin
;
BZD
;
benzodiazepine
;
DBU
;
1
;
8-diazabicycloundec-7-ene
;
DIPEA
;
N
;
N-Diisoprop
yl
eth
yl
amine
;
DMAD
;
dimeth
yl
acet
yl
enedicarbox
yl
ate
;
DNA
;
Deoxyribonucleic acid
;
EGFR
;
Epidermal growth factor receptor
;
GABA
;
Gamma-aminobutyric acid
;
MAO
;
monoamine oxidase
;
MES
;
maximal electroshock seizure
;
MTT
;
3-(4
;
5-dimeth
yl
thiazol-2-
yl
)-2
;
5-diphen
yl
tetrazolium
;
MW
;
microwave
;
NIS
;
N-Iodosuccinimide
;
PARP
刊名:Bioorganic & Medicinal Chemistry
出版年:20
1
6
7.
Cyclic peptide-based potent and selective SIRT
1
/2 dual inhibitors harboring N
ε
-thioacet
yl
-lysine
作者:
Di Chen
;
Weiping Zheng
;
wzheng@ujs.edu.cn" class="auth_mail" title="E-mail the corresponding author
关键词:
β-NAD+
;
β-nicotinamide adenine dinucleotide
;
MBHA
;
4-meth
yl
benzhydr
yl
amine
;
SPPS
;
solid phase peptide synthesis
;
DMF
;
N
;
N-dimeth
yl
formamide
;
TFA
;
trifluoroacetic acid
;
DCM
;
dichloromethane
;
HBTU
;
2-(
1
H-
benzotriazol
e-
1
-
yl
)-
1
13 ;
3-tetrameth
yl
aminium hexafluorophosphate
;
NMM
;
N-meth
yl
morpholine
;
RP-HPLC
;
reversed-phase high performance liquid chromatography
;
HRMS
;
high-resolution mass spectrometry
;
IC50
;
the inhibitor concentration at which an enzymatic reaction velocity is reduced by 50%
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:20
1
6
8.
Cyclic non-opioid dynorphin A analogues for the bradykinin receptors
作者:
Yeon Sun Lee
a
;
yeon@email.arizona.edu" class="auth_mail" title="E-mail the corresponding author
;
Michael Remesic
a
;
Cyf Ramos-Colon
a
;
Sara M. Hall
a
;
Alexander Kuzmin
a
;
David Rankin
b
;
Frank Porreca
b
;
Josephine Lai
b
;
Victor J. Hruby
a
关键词:
BBB
;
blood brain barrier
;
BK
;
bradykinin
;
Boc
;
t-but
yl
oxycarbon
yl
;
BR
;
bradykinin receptor
;
CNS
;
central nervous system
;
DALKD
;
[des-Arg
1
0
;
Leu9]-kallidin
;
DIPEA
;
diisoprop
yl
eth
yl
amine
;
DMF
;
N
;
N-dimeth
yl
formamide
;
Dyn A
;
dynorphin A
;
Fmoc
;
fluoren
yl
meth
yl
oxycarbon
yl
;
HBTU
;
2-(
1
H-
benzotriazol
e-
1
-
yl
)-
1
13 ;
3-tetrameth
yl
aminium hexafluorophosphate
;
HOBt
;
N-hydroxy
benzotriazol
e
;
i.pl.
;
intraplantar
;
MS
;
mass spectroscopy
;
Pbf
;
2
246 ;
7-pentameth
yl
dihydrobenzofuran-5-sulfon
yl
;
RP-HPLC
;
reversed-phas
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:20
1
6
9.
Inhibition of am
yl
oid fibril formation and cytotoxicity by caffeic acid-conjugated am
yl
oid-β C-terminal peptides
作者:
Takuya Arai
a
;
b
;
Akiko Ohno
c
;
Kazunori Mori
b
;
Hiroshi Kuwata
b
;
Mirei Mizuno
b
;
Kohei Imai
b
;
Shuntaro Hara
b
;
Motoko Shibanuma
b
;
Masaaki Kurihara
c
;
Naoki Miyata
a
;
Hidehiko Nakagawa
a
;
Kiyoshi Fukuhara
b
;
fukuhara@pharm.showa-u.ac.jp" class="auth_mail" title="E-mail the corresponding author
关键词:
Aβ
;
am
yl
oid-β
;
AD
;
Alzheimer&rsquo
;
s disease
;
CA
;
caffeic acid
;
DCFH-DA
;
2&prime
;
7&prime
;
-dichlorodihydrofluorescein diacetate
;
DHCA
;
dihydrocaffeic acid
;
DIPEA
;
N
;
N-diisoprop
yl
eth
yl
amine
;
DMF
;
N
;
N-dimeth
yl
formamide
;
DMSO
;
dimeth
yl
sulfoxide
;
Gly
;
glycine
;
HBTU
;
O-(
benzotriazol
-
1
-
yl
)- N
N ;
N&prime
;
N&prime
;
-tetrameth
yl
uronium hexafluorophosphate
;
HFIP
;
1
1133 ;
3-hexafluoro-2-propanol
;
HOBt
;
1
-hydroxy
benzotriazol
e
;
HRMS
;
high resolution mass spectrometry
;
PI
;
propidium iodide
;
ROS
;
reactive oxy
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:20
1
6
10.
Discovery and synthetic optimization of a novel scaffold for hydrophobic tunnel-targeted autotaxin inhibition
作者:
Lauren E. Ragle
a
;
Dilip J. Palanisamy
a
;
Margaux J. Joe
a
;
Rachel S. Stein
a
;
Derek D. Norman
b
;
Gabor Tigyi
b
;
Daniel L. Baker
a
;
Abby L. Parrill
a
;
关键词:
ATX/NPP2
;
autotaxin
;
DIPEA
;
N
;
N-diisoprop
yl
eth
yl
amine
;
DMF
;
N
;
N-dimeth
yl
formamide
;
DMSO
;
dimeth
yl
sulfoxide
;
GPCR
;
G-protein coupled receptor
;
GRI
;
Genomic Research Institute
;
HBTU
;
O-(
benzotriazol
-
1
-
yl
)-N
N ;
N&prime
;
N&prime
;
-tetrameth
yl
uronium hexafluorophosphate
;
LPC
;
lysophosphatid
yl
choline
;
LPA
;
lysophosphatidic acid
;
LysoPLD
;
lysophospholipase-D
;
MOE
;
Molecular Operating Environment
;
NPP
;
nucleotide pyrophosphatase phosphodiesterase
;
pNP-TMP
;
p-nitrophen
yl
thymidine-5&prime
;
-monophosphate
;
p
刊名:Bioorganic & Medicinal Chemistry
出版年:20
1
6
1
2
3
4
5
6
7
8
9
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