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Elsevier电子期刊(3225)
Wiley电子期刊(46)
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ACS电子期刊(336)
在“
Elsevier电子期刊
”中,
命中:
3,225
条,耗时:0.0529772 秒
在所有数据库中总计命中:
5,112
条
1.
Food, gastrointestinal pH, and models of
oral
drug
absorption
作者:
Ahmad Y. Abuhelwa
;
Ahmad.Abuhelwa@mymail.unisa.edu.au
;
Desmond B. Williams
Des.Williams@unisa.edu.au
;
Richard N. Upton
Richard.Upton@unisa.edu.au
;
David J.R. Foster
David.Foster@unisa.edu.au
关键词:
Gastrointestinal pH
;
Predicting
oral
absorption
;
Food-drug interactions
;
Empirical
absorption
models
;
Physiologically-based pharmacokinetic (PBPK) models
刊名:European Journal of Pharmaceutics and Biopharmaceutics
出版年:2017
2.
Development of novel self-assembled ES-PLGA hybrid nanoparticles for improving
oral
absorption
of doxorubicin hydrochloride by P-gp inhibition: In vitro and in vivo evaluation
作者:
Jia Wang
a
;
Lin Li
a
;
Lei Wu
b
;
Bingjun Sun
a
;
Yuqian Du
a
;
Jin Sun
a
;
c
;
Yongjun Wang
a
;
Qiang Fu
a
;
Peng Zhang
b
;
zhangpengspu@163.com
;
Zhonggui He
a
;
hezhonggui@vip.163.com
关键词:
Doxorubicin hydrochloride
;
Enoxaparin sodium
;
Electrostatic interaction
;
Self-assembled ES-PLGA nanoparticles
;
Oral
bioavailability
刊名:European Journal of Pharmaceutical Sciences
出版年:2017
3.
Polyarginine Nanocapsules as a Potential
Oral
Peptide Delivery Carrier
作者:
Giovanna Lollo
1
;
2
;
Ana Gonzalez-Paredes
1
;
2
;
Marcos Garcia-Fuentes
1
;
2
;
Pilar Calvo
3
;
Dolores Torres
1
;
Maria Jose Alonso
1
;
2
;
mariajalonso@usc.es
关键词:
nanotechnology
;
nanocapsules
;
colloid
;
biodegradable polymers
;
biomaterials
;
cancer
;
Caco-2 cells
;
oral
drug delivery
;
oral
absorption
;
surfactants
刊名:Journal of Pharmaceutical Sciences
出版年:2017
4.
In vivo evaluation of supersaturation/precipitation/re-dissolution behavior of cinnarizine, a lipophilic weak base, in the gastrointestinal tract: the key process of
oral
absorption
作者:
Yusuke Tanaka
;
y-tanaka@ps.hirokoku-u.ac.jp
;
Ayaka Kawakami
;
Ami Nanimatsu
;
Misaki Horio
;
Jumpei Matsuoka
;
Takami Wada
;
Satoshi Kasaoka
;
Hiroshi Yoshikawa
关键词:
Lipophilic weak base
;
Luminal concentration
;
Re-dissolution
;
Supersaturation
刊名:European Journal of Pharmaceutical Sciences
出版年:2017
5.
Improved
oral
absorption
profile of itraconazole in hypochlorhydria by self-micellizing solid dispersion approach
作者:
Yoshiki Kojo
;
Saori Matsunaga
;
Hiroki Suzuki
;
Hideyuki Sato
;
Yoshiki Seto
;
Satomi Onoue
;
onoue@u-shizuoka-ken.ac.jp
关键词:
ADI
;
acceptable daily intake
;
AUC
;
area under the curve of blood concentration vs. time
;
DLS
;
dynamic light scattering
;
DMEM
;
Dulbecco's modified Eagle's medium
;
DMSO
;
dimethyl sulfoxide
;
DSC
;
differential scanning calorimetry
;
GI
;
gastrointestinal
;
IEC6 cell
;
intestinal epithelioid cell line No.6 derived from neonatal rat ileum
;
ITZ
;
itraconazole
;
LD50
;
lethal dose 50%
;
LDH
;
lactate dehydrogenase
;
NaPB
;
sodium phosphate buffer
;
PLM
;
polarized light microscopy
;
PXRD
;
powder X-ray diffraction
;
RH
刊名:European Journal of Pharmaceutical Sciences
出版年:2017
6.
Multilayer micro-dispersing system as
oral
carriers for co-delivery of doxorubicin hydrochloride and P-gp inhibitor
作者:
Chao Feng
a
;
1
;
fengchao@ouc.edu.cn
;
Jing Li
a
;
Yuzhi Mu
a
;
Ming Kong
a
;
Yang Li
a
;
b
;
Mazhar Ali Raja
a
;
Xiao Jie Cheng
a
;
Ya Liu
a
;
Xi Guang Chen
a
;
1
;
xgchen@ouc.edu.cn
关键词:
Chitosan
;
Layer-by-layer
;
Oral
anticancer-drug delivery
刊名:International Journal of Biological Macromolecules
出版年:2017
7.
IMI -
oral
biopharmaceutics tools project - evaluation of bottom-up PBPK prediction success part 1: Characterisation of the OrBiTo database of compounds
作者:
Alison Margolskee
a
;
alison.margolskee@manchester.ac.uk
;
Adam S. Darwich
a
;
Xavier Pepin
b
;
c
;
Shriram M. Pathak
d
;
Michael B. Bolger
e
;
Leon Aarons
a
;
Amin Rostami-Hodjegan
a
;
d
;
Jonas Angstenberger
f
;
Franziska Graf
f
;
Loic Laplanche
f
;
Thomas Mü
;
ller
f
;
Sara Carlert
g
;
Pankaj Daga
h
;
Dó
;
nal Murphy
b
;
Christer Tannergren
g
;
Mohammed Yasin
b
;
Susanne Greschat-Schade
i
;
Wolfgang Mü
;
ck
i
;
Uwe Muenster
i
;
Dorina van der Mey
i
;
Kerstin Julia Frank
j
;
Richard Lloyd
k
;
Lieve Adriaenssen
l
;
Jan Bevernage
l
;
Loeckie De Zwart
l
;
Dominique Swerts
l
;
Christophe Tistaert
l
;
An Van Den Bergh
l
;
Achiel Van Peer
l
;
Stefania Beato
m
;
Anh-Thu Nguyen-Trung
m
;
Joanne Bennett
n
;
Mark McAllister
n
;
Mei Wong
n
;
Patricia Zane
o
;
Cé
;
line Ollier
c
;
Pascale Vicat
c
;
Markus Kolhmann
p
;
Alexander Marker
p
;
Priscilla Brun
c
;
Florent Mazuir
c
;
Sté
;
phane Beilles
c
;
Marta Venczel
p
;
Xavier Boulenc
c
;
Petra Loos
p
;
Hans Lennernä
;
s
q
;
Bertil Abrahamsson
g
关键词:
API
;
active pharmaceutical ingredient
;
AUC
;
area under the curve
;
BCS
;
biopharmaceutics classification system
;
BP
;
blood-to-plasma ratio
;
Cmax
;
maximum concentration
;
CL
;
clearance
;
Do
;
dose number according to BCS
;
DDI
;
drug-drug interaction
;
EFPIA
;
European Federation of Pharmaceutical Industries and Associations
;
F
oral
;
absolute
oral
bioavailability
;
Frel
;
relative bioavailability
;
fup
;
fraction unbound in plasma
;
IMI
;
Innovative Medicines Initiative
;
LogP
;
logarithm of the octanol/water part
刊名:European Journal of Pharmaceutical Sciences
出版年:2017
8.
Biokinetics of food additive silica nanoparticles and their interactions with food components
作者:
Jeong-A Lee
a
;
1
;
Mi-Kyung Kim
a
;
1
;
Jae Ho Song
b
;
1
;
Mi-Rae Jo
a
;
Jin Yu
a
;
Kyoung-Min Kim
b
;
Young-Rok Kim
c
;
youngkim@khu.ac.kr
;
Jae-Min Oh
b
;
jaemin.oh@yonsei.ac.kr
;
Soo-Jin Choi
a
;
sjchoi@swu.ac.kr
关键词:
Oral
absorption
;
Size effect
;
Silica nanoparticles
;
Intestinal transport
;
Interaction
;
Food component
;
Surface interaction
刊名:Colloids and Surfaces B: Biointerfaces
出版年:2017
9.
Novel amphiphilic chitosan nanocarriers for sustained
oral
delivery of hydrophobic drugs
作者:
Marjan Motiei
a
;
Soheila Kashanian
b
;
c
;
kashanian_s@yahoo.com
关键词:
Amphiphilic chitosan nanocarriers
;
Oral
delivery
;
Hydrophobic drug
;
Cross linker
;
Acidic condition
刊名:European Journal of Pharmaceutical Sciences
出版年:2017
10.
Synergistic role of solid lipid and porous silica in improving the
oral
delivery of weakly basic poorly water soluble drugs
作者:
Rokhsana Yasmin
;
Shasha Rao
;
Kristen Bremmell
;
Clive Prestidge
;
Clive.Prestidge@unisa.edu.au
关键词:
Oral
delivery
;
Poorly water soluble drugs
;
Solid lipid
;
Porous silica
;
Solubilization
刊名:European Journal of Pharmaceutical Sciences
出版年:2017
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