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Elsevier电子期刊(34)
ACS电子期刊(8)
在“
Elsevier电子期刊
”中,
命中:
34
条,耗时:0.0269875 秒
在所有数据库中总计命中:
42
条
1.
Synthesis and structure-activity r
el
ationship of 2-phenyliminochromene derivatives as inhibitors for aldo-keto reductase (AKR) 1B10
作者:
Satoshi Endo
;
Dawei Hu
;
Miho Suyama
;
Toshiyuki Matsunaga
;
Kenji Sugimoto
;
Yuji Matsuya
;
Ossama
El
-
Kabbani
;
Kazuo Kuwata
;
Akira Hara
;
Yukio Kitade
;
Naoki Toyooka
关键词:
AKR
;
aldo&ndash
;
keto reductase
;
FBS
;
fetal bovine serum
;
SAR
;
structure&ndash
;
activity r
el
ationship
刊名:Bioorganic and Medicinal Chemistry
出版年:2013
2.
Rabbit 3-hydroxyhexobarbital dehydrogenase is a NADPH-preferring reductase with broad substrate specificity for ketosteroids, prostaglandin D
2
, and other endogenous and xenobiotic carbonyl compounds
作者:
Satoshi Endo
;
Toshiyuki Matsunaga
;
Atsuko Matsumoto
;
Yuki Arai
;
Satoshi Ohno
;
Ossama
El
-
Kabbani
;
Kazuo Tajima
;
Yasuo Bunai
;
Shigeru Yamano
;
Akira Hara
;
Yukio Kitade
关键词:
3HB
;
3-hydroxyhexobarbital
;
3OB
;
3-oxohexobarbital
;
3HBD
;
3-hydroxyhexobarbital dehydrogenase
;
AKR
;
aldo-keto reductase
;
HSD
;
hydroxysteroid dehydrogenase
;
PG
;
prostaglandin
;
TBE
;
6-tert-butyl-2
;
3-epoxy-5-cyclohexene-1
;
4-dione
;
4R-TBEH
;
6-tert-butyl-2
;
3-e
刊名:Biochemical Pharmacology
出版年:2013
3.
Characterization of rabbit aldose reductase-like protein with 3¦Â-hydroxysteroid dehydrogenase activity
作者:
Satoshi Endo
;
Toshiyuki Matsunaga
;
Sho Kumada
;
Airi Fujimoto
;
Satoshi Ohno
;
Ossama
El
-
Kabbani
;
Dawei Hu
;
Naoki Toyooka
;
Jun¡¯ichi Mano
;
Kazuo Tajima
;
Akira Hara
关键词:
AKR1B10
;
Aldo&ndash
;
keto reductase
;
Aldose reductase
;
3¦Â-Hydroxysteroid dehydrogenase
;
4-Oxo-2-nonenal
刊名:Archives of Biochemistry and Biophysics
出版年:2012
4.
Structure-based optimization and biological evaluation of human 20α-hydroxysteroid dehydrogenase (AKR1C1) salicylic acid-based inhibitors
作者:
Ossama
El
-
Kabbani
;
Peter J. Scamm
el
ls
;
Tom Day
;
Urmi Dhagat
;
Satoshi Endo
;
Toshiyuki Matsunaga
;
Midori Soda
;
Akira Hara
关键词:
Aldo-keto reductase
;
3-Bromo-5-phenylsalicylic acid
;
Cancer
;
Drug design
;
Human 20α
;
-hydroxysteroid dehydrogenase
;
Human 3α
;
-hydroxysteroid dehydrogenase
刊名:European Journal of Medicinal Chemistry
出版年:2010
5.
Structure of aldehyde reductase in ternary complex with a 5-arylidene-2,4-thiazolidinedione aldose reductase inhibitor
作者:
Vincenzo Carbone
;
Marco Giglio
;
Rol
;
Chung
;
Trevor Huyton
;
Julian Adams
;
Rosanna Maccari
;
Rosaria Ottana
;
Akira Hara
;
Ossama
El
-
Kabbani
关键词:
Aldo–
;
keto reductase
;
5-Arylidene-2
;
4-thiazolidinedione
;
Aldehyde reductase
;
Aldose reductase
;
Ternary complex
;
Enzyme inhibition
刊名:European Journal of Medicinal Chemistry
出版年:2010
6.
Chromene-3-carboxamide derivatives discovered from virtual screening as potent inhibitors of the tumour maker, AKR1B10
作者:
Satoshi Endo
;
Toshiyuki Matsunaga
;
Kazuo Kuwata
;
Hai-Tao Zhao
;
Ossama
El
-
Kabbani
;
Yukio Kitade
;
Akira Hara
关键词:
AKR1B10
;
Aldose reductase-like protein
;
Aldose reductase
;
Aldehyde reductase
;
Inhibition s
el
ectivity
;
Molecular docking
刊名:Bioorganic and Medicinal Chemistry
出版年:2010
7.
S
el
ectivity determinants of inhibitor binding to the tumour marker human aldose reductase-like protein (AKR1B10) discovered from molecular docking and database screening
作者:
Hai-Tao Zhao
;
Midori Soda
;
Satoshi Endo
;
Akira Hara
;
Ossama
El
-
Kabbani
关键词:
Aldo-keto reductase
;
9-Methyl-2
3 ;
7-trihydroxy-6-fluorone
;
Aldose reductase
;
Aldose reductase-like protein
刊名:European Journal of Medicinal Chemistry
出版年:2010
8.
Properties and tissue distribution of a nov
el
aldo–keto reductase encoding in a rat gene (Akr1b10)
作者:
Satoshi Endo
;
Toshiyuki Matsunaga
;
Tsukasa Kuragano
;
Satoshi Ohno
;
Yukio Kitade
;
Kazuo Tajima
;
Ossama
El
-
Kabbani
;
Akira Hara
关键词:
Aldo–
;
keto reductase superfamily
;
AKR1B10
;
Aldose reductase
;
Glycation
;
Oxidative stress
;
4-Oxo-2-nonenal
;
4-Hydroxy-2-nonenal
;
3-Deoxyglucosone
刊名:Archives of Biochemistry and Biophysics
出版年:2010
9.
Factorizing the role of a critical leucine residue in the binding of substrate to human 20α-hydroxysteroid dehydrogenase (AKR1C1): Molecular mod
el
ing and kinetic studies of the Leu308Val mutant enzyme
作者:
Urmi Dhagat
;
Satoshi Endo
;
Midori Soda
;
Akira Hara
;
Ossama
El
-
Kabbani
关键词:
Hydroxysteroid dehydrogenase
;
Aldo–
;
keto reductase
;
AKR1C1
;
Progesterone
;
Substrate s
el
ectivity
;
GABA
A
receptor
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2010
10.
Nitric oxide mitigates apoptosis in human endoth
el
ial c
el
ls induced by 9,10-phenanthrenequinone: Role of proteasomal function
作者:
Toshiyuki Matsunaga
;
Marina Arakaki
;
Tetsuro Kamiya
;
Mariko Haga
;
Satoshi Endo
;
Ossama
El
-
Kabbani
;
Akira Hara
关键词:9 ;
10-Phenanthrenequinone
;
Nitric oxide
;
Proteasome
;
Oxidative stress
;
Endoth
el
ial c
el
l
刊名:Toxicology
出版年:2010
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