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Wiley电子期刊(28)
NATURE电子期刊(20)
ACS电子期刊(175)
SpringerLink电子期刊(1026)
Elsevier电子期刊(2980)
在“
Elsevier电子期刊
”中,
命中:
2,980
条,耗时:0.0319851 秒
在所有数据库中总计命中:
4,229
条
1.
RAM-589.555 a new
Polymerase
-1
inhibitor
as innovative targeted-treatment for multiple sclerosis
作者:
A Achiron
a
;
b
;
R Zilkha-Falb
a
;
1
;
R Mashiach
c
;
M Gurevich
a
;
1
;
gurevich@sheba.health.gov.il
关键词:
AUC
;
area under curve
;
Dpi
;
day post immunization
;
EAE
;
experimental autoimmune encephalomyelitis
;
MOG
;
myelin oligodendrocyte glycoprotein
;
MS
;
multiple sclerosis
;
POL1
;
RNA
Polymerase
-1
;
POL2
;
RNA
Polymerase
-2
;
RR
;
relapsing-remitting
;
SPCs
;
Splenocytes
刊名:Journal of Neuroimmunology
出版年:2017
2.
Association of plasminogen activator
inhibitor
-1 and vitamin D receptor expression with the risk of keloid disease in a Chinese population
作者:
Zhen-Hua Gong
;
Jian-Feng Ji
;
Jun Yang
;
Tie Xiang
;
Chang-Kai Zhou
;
Xuan-Liang Pan
;
Jian Yao
;
pxuanliang@sina.com
关键词:
Chinese population
;
Keloid disease
;
Peripheral blood lymphocytes
;
Plasminogen activator
inhibitor
;
Vitamin D receptor
刊名:The Kaohsiung Journal of Medical Sciences
出版年:2017
3.
Conditional knockout of TFPI-1 in VSMCs of mice accelerates atherosclerosis by enhancing AMOT/YAP pathway
作者:
Jiajun Xiao
a
;
Kaiyue Jin
a
;
Jiping Wang
a
;
Jing Ma
a
;
Jin Zhang
a
;
Nan Jiang
a
;
Huijun Wang
b
;
Xinping Luo
c
;
Jian Fei
d
;
Zhugang Wang
d
;
Xiao Yang
e
;
Duan Ma
a
;
b
;
duanma@fudan.edu.cn
关键词:
TFPI-1
;
tissue factor pathway
inhibitor
-1
;
VSMC
;
vascular smooth muscle cells
;
ApoE
;
apolipoprotein E
;
Cre
;
cyclization recombination
;
GI
;
gene inactivation
;
PCR
;
polymerase
chain reaction
;
AMOT
;
angiomotin
;
YAP
;
Yes-associated protein 1
;
CTGF
;
connective tissue growth factor
;
SLUG
;
snail family zinc finger 2
刊名:International Journal of Cardiology
出版年:2017
4.
Class I lysine deacetylases promote glucocorticoid-induced transcriptional repression through functional interaction with LSD1
作者:
Nina M. Patrick
a
;
b
;
Chanel A. Griggs
b
;
Ali L. Icenogle
b
;
Maryam M. Gilpatrick
b
;
Vineela Kadiyala
b
;
c
;
1
;
Rosa Jaime-Frias
b
;
Catharine L. Smith
;
PhD
b
;
csmith@pharmacy.arizona.edu
关键词:
KDAC
;
lysine deacetylase
;
KDACi
;
lysine deacetylase
inhibitor
;
KAT
;
lysine acetyltransferase
;
GR
;
glucocorticoid receptor
;
VPA
;
valproic acid
;
NR
;
nuclear receptor
;
Dex
;
dexamethasone
;
GAPDH
;
glyceraldehyde 3-phosphate dehydrogenase
;
HDAC
;
histone deacetylase
;
HDACi
;
HDAC
inhibitor
;
HAT
;
histone acetyltransferase
;
RT-qPCR
;
real time quantitative
polymerase
chain reaction
;
Ct
;
threshold cycle
;
siRNA
;
small interfering RNA
;
LSD1
;
lysine-specific demethylase 1
;
AR
;
androgen receptor
;
CoREST
;
co-rep
刊名:The Journal of Steroid Biochemistry and Molecular Biology
出版年:2017
5.
Shikonin inhibits gefitinib-resistant non-small cell lung cancer by inhibiting TrxR and activating the EGFR proteasomal degradation pathway
作者:
Xia Li
1
;
Xing-Xing Fan
1
;
Ze-Bo Jiang
;
Wings TY Loo
;
Xiao-Jun Yao
;
Elaine Lai-Han Leung
;
lhleung@must.edu.mo
;
Louis WC Chow
;
wcchow@must.edu.mo
;
Liang Liu
;
lliu@must.edu.mo
关键词:
NSCLC
;
non-small cell lung cancer cell
;
ROS
;
reactive oxygen species
;
EGFR
;
epidermal growth factor receptor
;
T790M
;
a substitution mutation of threonine with methionine at position 790 of EGFR
;
TrxR
;
thioredoxin reductases
;
MTT
;
3-(4
;
5-dimetrylthiazol)-2
;
5-diphenyltetrazolium bromide
;
DCFDA
;
dichlorofluorescein diacetate
;
PBS
;
phosphate-buffered saline
;
RIPA
;
radioimmunoprecipitation assay
;
PARP
;
poly (ADP-ribosyl)
polymerase
;
NAC
;
N-acetyl-l-cysteine
;
MG132
;
proteasomal degradation pathway inh
刊名:Pharmacological Research
出版年:2017
6.
Inhibiting poly ADP-ribosylation increases fatty acid oxidation and protects against fatty liver disease
作者:
Karim Gariani
1
;
Dongryeol Ryu
1
;
&dagger
;
;
Keir J. Menzies
1
;
3
;
&dagger
;
;
Hyon-Seung Yi
5
;
Sokrates Stein
2
;
4
;
Hongbo Zhang
1
;
Alessia Perino
2
;
Vera Lemos
2
;
Elena Katsyuba
1
;
Pooja Jha
1
;
Sandrine Vijgen
7
;
Laura Rubbia-Brandt
7
;
Yong Kyung Kim
5
;
Jung Tae Kim
6
;
Koon Soon Kim
5
;
Minho Shong
5
;
Kristina Schoonjans
2
;
Johan Auwerx
1
;
admin.auwerx@epfl.ch
关键词:
Non-alcoholic fatty liver disease
;
Poly ADP-ribosylation
;
Sirtuin
;
PARP
inhibitor
;
PARylation
;
NAD
刊名:Journal of Hepatology
出版年:2017
7.
Discovery of hepatitis B virus capsid assembly
inhibitor
s leading to a heteroaryldihydropyrimidine based clinical candidate (GLS4)
作者:
Qingyun Ren
a
;
b
;
Xinchang Liu
a
;
b
;
Zhonghua Luo
a
;
Jing Li
a
;
Chaolei Wang
a
;
b
;
Siegfried Goldmann
a
;
sigi@hecpharm.com
;
Jiancun Zhang
c
;
Yingjun Zhang
a
;
zhangyingjun@hecpharm.com
关键词:
HBV
;
Capsid assembly
inhibitor
;
SAR
;
GLS4
;
Pharmacokinetics
;
Safety evaluation
刊名:Bioorganic & Medicinal Chemistry
出版年:2017
8.
Mitochondrial defects arise from nucleoside/nucleotide reverse transcriptase
inhibitor
s in neurons: Potential contribution to HIV-associated neurocognitive disorders
作者:
Kui-Ming Hung
a
;
b
;
Pei-Chun Chen
b
;
Han-Chieh Hsieh
c
;
Marcus J Calkins
a
;
mjcalkins@mail.ncku.edu.tw
关键词:
NRTI
;
nucleoside/nucleotide reverse transcriptase
inhibitor
;
HAND
;
HIV-associated neurocognitive disorders
;
cART
;
combination antiretroviral therapy
;
pol γ
;
polymerase
γ
;
mtDNA
;
mitochondrial DNA
;
ddI
;
didanosine
;
AZT
;
zidovudine
;
FTC
;
emtricitabine
;
TDF
;
tenofovir
;
ddC
;
zalcitabine
;
d4T
;
stavudine
;
3TC
;
lamivudine
;
ABC
;
abacavir
;
PGC-1α
;
peroxisome proliferator-activated receptor γ coactivator 1α
;
mtUPR
;
mitochondrial unfolded protein response
;
CO1
;
Cytochrome oxidase I
;
ND1
;
NADH Dehydrogenase
刊名:Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
出版年:2017
9.
Davallia bilabiata exhibits anti-angiogenic effect with modified MMP-2/TIMP-2 secretion and inhibited VEGF ligand/receptors expression in vascular endothelial cells
作者:
Chun-Ting Liu
a
;
1
;
Kuo-Wei Bi
a
;
1
;
Chao-Chun Huang
b
;
Hsiao-Ting Wu
a
;
Hui-Ya Ho
c
;
Jong-Hwei S. Pang
d
;
e
;
jonghwei@mail.cgu.edu.tw
;
Sheng-Teng Huang
f
;
g
;
sheng.teng@yahoo.com
关键词:
D. bilabiata
;
Davallia bilabiata
;
MMPs
;
matrix metalloproteinases
;
VEGF
;
vascular endothelial growth factor
;
VEGFR
;
vascular endothelial growth factor receptor
;
CAM
;
chorioallantoic membrane
;
TIMP
;
tissue
inhibitor
of metalloproteinase
;
RECK
;
reversion-inducing cysteine-rich protein with kazal motifs
;
qRT-PCR
;
real time
polymerase
chain reaction
;
TNF-α
;
tumor necrosis factor-α
;
IL-1β
;
interleukin-1β
;
CAMs
;
cellular adhesion molecules
;
ECM
;
extracellular matrix
;
RA
;
rheumatoid arthritis
;
D. formo
刊名:Journal of Ethnopharmacology
出版年:2017
10.
MicroRNA138 regulates keratin 17 protein expression to affect HaCaT cell proliferation and apoptosis by targeting hTERT in psoriasis vulgaris
作者:
Shi-Jun Feng
a
;
drfeng0819@126.com
;
Rui-Qi Chu
b
;
Jing Ma
a
;
Zheng-Xiang Wang
a
;
Guang-Jing Zhang
a
;
Xiu-Fang Yang
a
;
Zhi Song
c
;
Yun-Yi Ma
c
关键词:
Psoriasis vulgaris
;
MicroRNA-138
;
Keratin 17
;
hTERT
;
HaCaT cells
;
Proliferation
;
Apoptosis
刊名:Biomedicine & Pharmacotherapy
出版年:2017
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