设为首页
收藏本站
网站地图
|
English
|
公务邮箱
About the library
Background
History
Leadership
Organization
Readers' Guide
Opening Hours
Collections
Help Via Email
Publications
Electronic Information Resources
常用资源
电子图书
期刊论文
学位会议
外文资源
特色专题
内部出版物
Wiley电子期刊(14)
NATURE电子期刊(1)
ACS电子期刊(115)
SpringerLink电子期刊(85)
Elsevier电子期刊(332)
在“
Elsevier电子期刊
”中,
命中:
332
条,耗时:0.0549752 秒
在所有数据库中总计命中:
547
条
1.
Prodrug
approach
: An overview of recent cases
作者:
Valentina Abet
;
Fabiana Filace
;
Javier Recio
;
Julio Alvarez-Builla
;
julio.alvarez@uah.es
;
Carolina Burgos
;
carolina.burgos@uah.es
关键词:
Prodrug
;
Carrier-linked
prodrug
;
Bioprecursors
刊名:European Journal of Medicinal Chemistry
出版年:2017
2.
Design, preparation and characterization of pH-responsive
prodrug
micelles with hydrolyzable anhydride linkages for controlled drug delivery
作者:
Girija Seetharaman
1
;
Adarsh R. Kallar
1
;
Vineeth M. Vijayan
;
Jayabalan Muthu
;
Shivaram Selvam
;
sselvam@sctimst.ac.in
关键词:
pH responsive
;
Prodrug
micelles
;
Crosslinkable
;
Anhydride linkages
;
Polypropylene fumarate
;
Controlled release
刊名:Journal of Colloid and Interface Science
出版年:2017
3.
Targeted hydroxyethyl starch
prodrug
for inhibiting the growth and metastasis of prostate cancer
作者:
Kaidong Zhao
a
;
b
;
c
;
Di Li
b
;
Weiguo Xu
b
;
Jianxun Ding
b
;
jxding@ciac.ac.cn
;
Weiqian Jiang
d
;
Mingqiang Li
b
;
ml3777@columbia.edu
;
Chunxi Wang
a
;
chunxi_wang@126.com
;
Xuesi Chen
b
关键词:
Hydroxyethyl starch
prodrug
;
Schiff base bond
;
Targeted drug delivery
;
Chemotherapy
;
Prostate cancer therapy
刊名:Biomaterials
出版年:2017
4.
Self-immolative nanoparticles for simultaneous delivery of microRNA and targeting of polyamine metabolism in combination cancer therapy
作者:
Ying Xie
a
;
Tracy Murray-Stewart
b
;
Yazhe Wang
a
;
Fei Yu
a
;
Jing Li
a
;
Laurence J. Marton
c
;
Robert A. Casero Jr.
b
;
David Oupický
;
a
;
david.oupicky@unmc.edu
关键词:
Self-immolative polymer
;
Polyplexes
;
Nanoparticles
;
Polyamine metabolism
;
miRNA
;
Combination delivery
;
Bisethylnorspermine
;
Cancer
刊名:Journal of Controlled Release
出版年:2017
5.
Topical iontophoretic delivery of ionizable, biolabile aciclovir
prodrug
s: A rational
approach
to improve cutaneous bioavailability
作者:
Yong Chen
;
Ingo Alberti
;
Yogeshvar N. Kalia
;
yogi.kalia@unige.ch" class="auth_mail" title="E-mail the corresponding author
关键词:
Aciclovir
;
Prodrug
;
Stability
;
Iontophoresis
;
Skin
;
Skin retention
;
Bioconversion
刊名:European Journal of Pharmaceutics and Biopharmaceutics
出版年:2016
6.
Antimycobacterial activity of pyrazinoate
prodrug
s in replicating and non-replicating Mycobacterium tuberculosis
作者:
Natanael Dante Segretti
a
;
Cristina Kortstee Simõ
;
es
b
;
Michelle Fidelis Corrê
;
a
b
;
Veni Maria Andres Felli
a
;
Marcelo Miyata
c
;
Sang Hyun Cho
d
;
Scott Gary Franzblau
d
;
Joã
;
o Paulo dos Santos Fernandes
b
;
joao.fernandes@unifesp.br" class="auth_mail" title="E-mail the corresponding author
关键词:
Antimycobacterial
prodrug
;
Duplicated
prodrug
;
LORA assay
;
Pyrazinoate ester
刊名:Tuberculosis
出版年:2016
7.
Integrating a novel SN38
prodrug
into the PEGylated liposomal system as a robust platform for efficient cancer therapy in solid tumors
作者:
Tao Fang
a
;
1
;
Yuehan Dong
b
;
1
;
Xiaomin Zhang
c
;
Ke Xie
c
;
Li Lin
a
;
Hangxiang Wang
a
;
c
;
wanghx@zju.edu.cn" class="auth_mail" title="E-mail the corresponding author
关键词:
Prodrug
;
Liposome
;
Supramolecular nanoassembly
;
Drug delivery
;
Cancer therapy
刊名:International Journal of Pharmaceutics
出版年:2016
8.
Modulating lipophilicity of rohitukine via
prodrug
approach
: Preparation, characterization, and in vitro enzymatic hydrolysis in biorelevant media
作者:
Vikas Kumar
a
;
b
;
Sonali S. Bharate
a
;
sonalibharate@gmail.com" class="auth_mail" title="E-mail the corresponding author
;
Ram A. Vishwakarma
b
;
c
;
ram@iiim.ac.in" class="auth_mail" title="E-mail the corresponding author
关键词:
log D
;
distribution coefficient
;
log P
;
partition coefficient
;
NCEs
;
new chemical entities
;
PBS
;
phosphate buffer saline
;
SGF
;
Simulated gastric fluid
;
SIF
;
Simulated intestinal fluid
;
RP-HPLC
;
reverse-phase high-performance liquid chromatography
;
tR
;
retention time
;
UV
;
ultraviolet
;
HMBC
;
Heteronuclear Multiple Bond Correlation
;
GI50
;
Concentration for 50% growth inhibition
刊名:European Journal of Pharmaceutical Sciences
出版年:2016
9.
Modification of existing antibiotics in the form of precursor
prodrug
s that can be subsequently activated by nitroreductases of the target pathogen
作者:
Ayhan Ç
;
elik
a
;
ayhancelik@gtu.edu.tr" class="auth_mail" title="E-mail the corresponding author
;
Gü
;
lden Yetiş
a
;
Mehmet Ay
b
;
Tuğba Gü
;
ngö
;
r
b
关键词:
Nitroreductase
;
Prodrug
s
;
Sulfamethoxazole
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2016
10.
Gene silencing by 2′-O-methyldithiomethyl-modified siRNA, a
prodrug
-type siRNA responsive to reducing environment
作者:
Yosuke Ochi
;
Mieko Imai
;
Osamu Nakagawa
&dagger
;
;
Junsuke Hayashi
;
Shun-ichi Wada
;
Hidehito Urata
;
urata@gly.oups.ac.jp" class="auth_mail" title="E-mail the corresponding author
关键词:
siRNA
;
Prodrug
-type RNA
;
Reducing environment
;
2&prime
;
-O-Methyldithiomethyl modification
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2016
1
2
3
4
5
6
7
8
9
按检索点细分(332)
题名(33)
关键词(4)
文摘(264)
按出版年细分(332)
2027年及以后(10)
2017年(4)
2016年(23)
2015年(8)
2013年(21)
2012年(18)
2011年(26)
2010年(21)
2009年(17)
2008年(11)
2007年(20)
2006年(8)
2005年(12)
2004年(14)
2003年(14)
2002年(11)
2001年(13)
2000年(12)
2000年及以前(69)
NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via
email
.