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Elsevier电子期刊(11)
ACS电子期刊(4)
在“
Elsevier电子期刊
”中,
命中:
11
条,耗时:0.0149913 秒
在所有数据库中总计命中:
15
条
1.
Novel tetrahydropyran analogs as dipeptidyl peptidase IV inhibitors: Profile of clinical candidate (2R,3S,5R)-2-(2,5-difluorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c]pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-amine (23)
作者:
Tesfaye Biftu
;
Xiaoxia Qian
;
Ping Chen
;
Dennis Feng
;
Giovanna Scapin
;
Ying-Duo Gao
;
Jason Cox
;
Ranabir
Sinha
Roy
;
George Eiermann
;
Huabing He
;
Kathy Lyons
;
Gino Salituro
;
Sangita Patel
;
Alex
;
er Petrov
;
Feng Xu
;
Shiyao Sherrie Xu
;
Bei Zhang
;
Charles Caldwell
;
Joseph K. Wu
;
Kathy Lyons
;
et al.
关键词:
DPP-IV
;
Tetrahydropyran
;
DPP-4 inhibitors
;
Diabetes
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2013
2.
Inhibition of DPP-4 with sitagliptin improves glycemic control and restores islet cell mass and function in a rodent model of type 2 diabetes
作者:
James Mu
;
Aleks
;
r Petrov
;
George J. Eiermann
;
John Woods
;
Yun-Ping Zhou
;
Zhihua Li
;
Emanuel Zycb
;
Yue Feng
;
Lan Zhu
;
Ranabir
Sinha
Roy
;
Andrew D. Howard
;
Cai Li
;
Nancy A. Thornberry
;
Bei B. Zhang
关键词:
Dipeptidyl peptidase-4 (DPP-4)
;
Sitagliptin
;
Type 2 diabetes
;
β
;
cell mass
刊名:European Journal of Pharmacology
出版年:2009
3.
Optimization of 1,4-diazepan-2-one containing dipeptidyl peptidase IV inhibitors for the treatment of type 2 diabetes
作者:
Gui-Bai Liang
;
Xiaoxia Qian
;
Dennis Feng
;
Tesfaye Biftu
;
George Eiermann
;
Huaibing He
;
Barbara Leiting
;
Kathy Lyons
;
Aleks
;
r Petrov
;
Ranabir
Sinha
-
Roy
;
et al.
关键词:
Type 2 diabetes
;
DPP-IV inhibitors
;
1
;
4-Diazepan-2-one
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2007
4.
Modeling assisted rational design of novel, potent, and selective pyrrolopyrimidine DPP-4 inhibitors
作者:
Ying-Duo Gao
;
Dennis Feng
;
Robert P. Sheridan
;
Giovanna Scapin
;
Sangita B. Patel
;
Joseph K. Wu
;
Xiaoping Zhang
;
Ranabir
Sinha
-
Roy
;
Nancy A. Thornberry
;
Ann E. Weber
;
et al.
关键词:
DPP-4
;
Molecular modeling
;
Potency
;
Selectivity against DPP-8/9
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2007
5.
Discovery of 3-aminopiperidines as potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitors
作者:
Jason M. Cox
;
Bart Harper
;
Anthony Mastracchio
;
Barbara Leiting
;
Ranabir
Sinha
Roy
;
Reshma A. Patel
;
Joseph K. Wu
;
Kathryn A. Lyons
;
Huaibing He
;
Shiyao Xu
;
Bing Zhu
;
Nancy A. Thornberry
;
Ann E. Weber
关键词:
Dipeptidyl peptidase IV
;
DPP-4
;
DPP8
;
DPP9
;
QPP
;
Aminopiperidine
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2007
6.
Direct interaction of a vancomycin derivative with bacterial enzymes involved in cell wall biosynthesis
作者:
Sinha
Roy
;
Ranabir
;
Yang
;
Ping
;
Kodali
;
Srinivas
;
Xiong
;
Yusheng
;
Kim
;
Ronald M.
;
Griffin
;
Patrick R.
;
et. al.
关键词:
Affinity chromatography
;
Glycopeptide
;
Peptidoglycan
;
Transglycosylase
;
Vancomycin
;
CBP-V
;
chlorobiphenyl vancomycin
;
DCB
;
3
;
4-dichlorobenzyloxybenzyl
;
DCB-PV
;
3
;
4-dichlorobenzyloxybenzyl putrescinyl vancomycin
;
MIC
;
minimum inhibitory concentration
;
MRSA
刊名:Chemistry & Biology
出版年:2001
7.
In vivo processing and antibiotic activity of microcin B17 analogs with varying ring content and altered bisheterocyclic sites
作者:
Roy
;
Ranabir
Sinha
;
Kelleher
;
Neil L
;
Milne
;
Jill C
;
Walsh
;
Christopher T
关键词:
antibiotic
;
gyrase
;
heterocycles
;
microcin B17
;
mutagenesis
刊名:Chemistry & Biology
出版年:1999
8.
Expressed protein ligation to probe regiospecificity of heterocyclization in the peptide antibiotic microcin B17
作者:
Roy
;
Ranabir
Sinha
;
Allen
;
Owen
;
Walsh
;
Christopher T
关键词:
heterocycles
;
intein
;
ligation
;
microcin B17
;
protein splicing
刊名:Chemistry & Biology
出版年:1999
9.
Kinetics and regioselectivity of peptide-to-heterocycle conversions by microcin B17 synthetase
作者:
Belshaw
;
Peter J.
;
Roy
;
Ranabir
Sinha
;
Kelleher
;
Neil L.
;
Walsh
;
Christopher T.
关键词:
antibiotics
;
microcin B17
;
oxazole
;
post-translational modification
;
thiazole
刊名:Chemistry & Biology
出版年:1998
10.
Role of the microcin B17 propeptide in substrate recognition: solution structure and mutational analysis of McbA
1−26
作者:
Ranabir
Sinha
Roy
;
Soyoun Kim
;
James D Baleja
;
Christopher T Walsh
刊名:Chemistry & Biology
出版年:1998
1
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