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Elsevier电子期刊(8)
ACS电子期刊(3)
在“
Elsevier电子期刊
”中,
命中:
8
条,耗时:0.0119941 秒
在所有数据库中总计命中:
11
条
1.
Discovery of 4-(4-aminopyrazolo[1,5-a][1,3,5]triazin-8-yl)benzamides as novel, highly potent and selective, orally bioavailable inhibitors of Tyrosine Threonine Kinase, TTK
作者:
Radoslaw Laufer
;
Radek.Laufer@oicr.on.ca" class="auth_mail" title="E-mail the corresponding author
;
Sze-Wan Li
;
Yong Liu
;
Grace Ng
;
Yunhui Lang
;
Miklos Feher
;
Richard
Brokx
;
Irina Beletskaya
;
Richard
Hodgson
;
Guodong Mao
;
Olga Plotnikova
;
Donald E. Awrey
;
Jacqueline M. Mason
;
Xin Wei
;
Dan Chi-Chia Lin
;
Yi Che
;
Reza Kiarash
;
Brian Madeira
;
Graham C. Fletcher
;
Tak W. Mak
;
Mark R. Bray
;
Henry W. Pauls
关键词:
Ar
;
aryl
;
ATP
;
Adenosine-5&prime
;
-triphosphate
;
AUC
;
area under the curve
;
BA
;
bioavailability
;
CYP
;
Cytochrome P450
;
DBU
;
1
;
8-diazabicyclo[5.4.0]undec-7-ene
;
DCM
;
dichloromethane
;
DIPEA
;
diisopropylethylamine
;
Δ
;
heat
;
DME
;
1
;
2-dimethoxyethane
;
DMF
;
N
;
N-dimethylformamide
;
DMSO
;
dimethyl sulfoxide
;
dppf
;
1
;
1&prime
;
-bis(diphenylphosphino)ferrocene
;
h
;
hour or human (in MS)
;
GI50
;
half maximal cell growth inhibitory concentration
;
Hb
;
hydrophobe
;
IC50
;
half maximal inhibitory concentration
;
m
;
mou
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2016
2.
Initial bronchoscopic treatment for patients with intraluminal bronchial carcinoids
作者:
Hes A.P.
Brokx
;
Elle K. Risse
;
Marinus A. Paul
;
Katrien Grü
;
nberg
;
Richard
P. Golding
;
Peter W.A. Kunst
;
Jan-Peter Eerenberg
;
Johan C. van Mourik
;
Pieter E. Postmus
;
Wolter J. Mooi
;
Tom G. Sutedj
关键词:
AA
;
Arachidonic acid
;
ACE
;
Antigen capture enzyme immunoassay
;
ADP
;
Adenosine diphosphate
;
AGT
;
Acquired Glanzmann's thrombasthenia
;
DAT
;
Direct anti-globulin test
;
MoAb
;
Monoclonal antibodies
;
PTLPD
;
Posttransplantation lymphoproliferative disorder
刊名:The Journal of Thoracic and Cardiovascular Surgery
出版年:2007
3.
Design and synthesis of thiazole-5-hydroxamic acids as novel histone deacetylase inhibitors
作者:
Sampath-Kumar An
;
an
;
John S. Ward
;
Richard
D.
Brokx
;
Trisha Denny
;
Mark R. Bray
;
Dinesh V. Patel
;
Xiao-Yi Xiao
关键词:
HDAC
;
Inhibitors
;
Synthesis
;
Antiproliferative
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2007
4.
Tandem Dimerization of the Human p53 Tetramerization Domain Stabilizes a Primary Dimer Intermediate and Dramatically Enhances its Oligomeric Stability
作者:
Gregory M.K. Poon
;
Richard
D.
Brokx
;
Michael Sung
;
Jean Garié
;
py
关键词:
p53
;
tetramerization domain
;
oligomerization
;
thermodynamics
;
folding intermediate
刊名:Journal of Molecular Biology
出版年:2007
5.
Mercaptoamide-based non-hydroxamic acid type histone deacetylase inhibitors
作者:
Anandan
;
Sampath-Kumar
;
Ward
;
John S.
;
Brokx
;
Richard
D.
;
Bray
;
Mark R.
;
Patel
;
Dinesh V.
;
et. al.
关键词:
Histone deacetylase inhibitor
;
Non-hydroxamates
;
Mercaptoamides
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2005
6.
Backbone dynamic properties of the central linker region of calcium-calmodulin in 35 % trifluoroethanol
作者:
Brokx
;
Richard
D.
;
Scheek
;
Ruud M.
;
Weljie
;
Aalim M.
;
Vogel
;
Hans J.
关键词:
Calmodulin
;
Trifluoroethanol
;
Backbone dynamics
;
Helix formation
;
Crystallization conditions
刊名:Journal of Structural Biology
出版年:2004
7.
Backbone dynamic properties of the central linker region of calcium-calmodulin in 35 % trifluoroethanol
作者:
Brokx
;
Richard
D.
;
Scheek
;
Ruud M.
;
Weljie
;
Aalim M.
;
Vogel
;
Hans J.
关键词:
Calmodulin
;
Trifluoroethanol
;
Backbone dynamics
;
Helix formation
;
Crystallization conditions
刊名:Journal of Structural Biology
出版年:2004
8.
Designing peptide-based scaffolds as drug delivery vehicles
作者:
Brokx
;
Richard
D.
;
Bisland
;
Stuart K.
;
Garié
;
py
;
Jean
关键词:
Branched peptide
;
Cytotoxic T-lymphocyte (CTL) epitope
;
Gene transfer
;
Peptide synthesis
;
Photodynamic therapy
;
Boc
;
t-butyloxycarbonyl
;
Ce6
;
chlorin e
6
;
CTL
;
cytotoxic T-lymphocyte
;
CTS
;
cytoplasmic translocation signal
;
Fmoc
;
9-fluorenylmethy
刊名:Journal of Controlled Release
出版年:2002
1
按检索点细分(8)
作者(8)
按出版年细分(8)
2016年(1)
2007年(3)
2005年(1)
2004年(2)
2002年(1)
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