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Springer电子图书(13)
SpringerLink电子期刊(3)
Elsevier电子期刊(18)
ACS电子期刊(5)
在“
Elsevier电子期刊
”中,
命中:
18
条,耗时:0.012994 秒
在所有数据库中总计命中:
39
条
1.
Effect Of A Nove
l
, Ora
l
Histamine H4R Antagonist On Histamine-Induced Pruritus In Hea
l
thy Subjects
作者:
A
l
exa P. Ko
ll
meier
;
Pau
l
Dunford
;
Xie Xu
;
Andrew Greenspan
;
Yichuan Xia
;
Bei Zhou
;
K
l
aus Francke
;
Robin
L
.
Thurmond
刊名:Journa
l
of A
ll
ergy and C
l
inica
l
Immuno
l
ogy
出版年:February, 2014
2.
Tricyc
l
ic aminopyrimidine histamine H
4
receptor antagonists
作者:
Brad M.
;
Sava
ll
;
;
;
bsava
ll
@its.jnj.com
;
L
aurent
;
Gomez
&dagger
;
;
Frank
;
Chavez
&Dagger
;
;
Michae
l
;
Curtis
§
;
;
Steven P.
;
Meduna
;
Aaron
;
Kearney
;
Pau
l
;
Dunford
;
Jeffery
;
Cowden
;
Robin
L
.
;
Thurmond
;
Chery
l
;
Grice
;
James P.
;
Edwards
关键词:
Histamine
;
Histamine H4
;
Antagonists
;
Benzofuran
;
Amino pyrimidine
;
Tricyc
l
ic
刊名:Bioorganic and Medicina
l
Chemistry Letters
出版年:2011
3.
Agonist/antagonist modu
l
ation in a series of 2-ary
l
benzimidazo
l
e H
4
receptor
l
igands
作者:
Brad M. Sava
ll
;
James P. Edwards
;
Jennifer D. Venab
l
e
;
Danie
l
J. Buzard
;
Robin
Thurmond
;
Michae
l
Hack
;
Patricia McGovern
关键词:
Histamine H
4
;
2-Ary
l
-benzimidazo
l
e
;
Benzimidazo
l
e
;
Agonist
;
Antagonist
刊名:Bioorganic and Medicina
l
Chemistry Letters
出版年:2010
4.
Discovery and SAR of nove
l
pyrazo
l
e-based thioethers as cathepsin S inhibitors: Part 1
作者:
A
l
ice Lee-Dutra
;
Danie
ll
e K. Wiener
;
Kristen
L
. Arienti
;
Jing
L
iu
;
Nee
l
ak
;
ha Mani
;
Michae
l
K. Ameriks
;
Frank U. Axe
;
Damara Gebauer
;
Pragnya J. Desai
;
Steven Nguyen
;
Mike R
;
a
l
;
Robin
L
.
Thurmond
;
Siqu
关键词:
Cathepsin
;
Protease
;
Thioether
刊名:Bioorganic and Medicina
l
Chemistry Letters
出版年:2010
5.
Diazinones as P2 rep
l
acements for pyrazo
l
e-based cathepsin S inhibitors
作者:
Michae
l
K. Ameriks
;
Scott D. Bembenek
;
Matthew T. Burdett
;
Ingrid C. Choong
;
James P. Edwards
;
Damara Gebauer
;
Yin Gu
;
L
ars Kar
l
sson
;
Hans E. Purkey
;
Bart
L
. Staker
;
Siquan Sun
;
Robin
L
.
Thurmond
;
Jia
关键词:
Cathepsin
;
Protease
;
Tethering
;
X-ray crysta
ll
ography
;
Fragment-based screening
刊名:Bioorganic and Medicina
l
Chemistry Letters
出版年:2010
6.
Thioether acetamides as P3 binding e
l
ements for tetrahydropyrido-pyrazo
l
e cathepsin S inhibitors
作者:
Danie
ll
e K. Wiener
;
A
l
ice Lee-Dutra
;
Scott Bembenek
;
Steven Nguyen
;
Robin
L
.
Thurmond
;
Siquan Sun
;
L
ars Kar
l
sson
;
Chery
l
A. Grice
;
Todd K. Jones
;
James P. Edwards
刊名:Bioorganic and Medicina
l
Chemistry Letters
出版年:2010
7.
Pyrazo
l
e-based cathepsin S inhibitors with ary
l
a
l
kynes as P1 binding e
l
ements
作者:
Michae
l
K. Ameriks
;
Frank U. Axe
;
Scott D. Bembenek
;
James P. Edwards
;
Yin Gu
;
L
ars Kar
l
sson
;
Mike R
;
a
l
;
Siquan Sun
;
Robin
L
.
Thurmond
;
Jian Zhu
关键词:
Cathepsin
;
Protease
;
A
l
kyne
;
X-ray crysta
ll
ography
刊名:Bioorganic and Medicina
l
Chemistry Letters
出版年:2009
8.
Pyrazo
l
e-based ary
l
a
l
kyne cathepsin S inhibitors. Part II: Optimization of ce
ll
u
l
ar potency
作者:
Michae
l
K. Ameriks
;
Hui Cai
;
James P. Edwards
;
Damara Gebauer
;
E
l
izabeth G
l
eason
;
Yin Gu
;
L
ars Kar
l
sson
;
Steven Nguyen
;
Siquan Sun
;
Robin
L
.
Thurmond
;
Jian Zhu
关键词:
Cathepsin
;
Protease
;
Invariant chain
;
L
ysosomotropism
刊名:Bioorganic and Medicina
l
Chemistry Letters
出版年:2009
9.
C
l
oning and pharmaco
l
ogica
l
characterization of the dog histamine H
4
receptor
作者:
Wen Jiang
;
Herman D.
L
im
;
Mai Zhang
;
Pragnya Desai
;
Heng Dai
;
Patricia M. Co
ll
ing
;
Rob
L
eurs
;
Robin
L
.
Thurmond
关键词:
Histamine receptor
;
L
igand binding
;
G protein-coup
l
ed receptor
;
Antihistamine
刊名:European Journa
l
of Pharmaco
l
ogy
出版年:2008
10.
Histamine H4 receptor expression is e
l
evated in human nasa
l
po
l
yp tissue
作者:
Adrienn Jó
;
kú
;
ti
;
É
;
va He
ll
inger
;
Andrea He
ll
inger
;
Zsuzsa Darvas
;
Andrá
;
s Fa
l
us
;
Robin
L
.
Thurmond
;
Andor Hirschberg
关键词:
Histamine
;
Eosinophi
l
cationic protein
;
H4 receptor
;
Nasa
l
po
l
yp
刊名:Ce
ll
Bio
l
ogy Internationa
l
出版年:2007
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