搜索页_+Sc-DHFR

设为首页

收藏本站

网站地图 | English | 公务邮箱

About the library

Background
History
Leadership
Organization

Readers' Guide

Opening Hours
Collections
Help Via Email

Publications

Electronic Information Resources

外文资源

Elsevier电子期刊(10)

在“Elsevier电子期刊”中，命中：10条，耗时：0.0529797 秒

在所有数据库中总计命中：15条

1.Transcriptome analysis of a CHO cell line expressing a recombinant therapeutic protein treated with inducers of protein expression

作者：Dina Fomina-Yadlin ; Mirna Mujacic ; Kathy Maggiora ; Garrett Quesnell ; Ramsey Saleem ; Jeffrey T. McGrew ; ^{jeff.mcgrew@justbiotherapeutics.com" class="auth_mail" title="E-mail the corresponding author}

关键词：CHO ; Chinese hamster ovary ; DHFR ; dihydrofolate reductase ; GO ; gene ontology ; GS ; glutamine synthetase ; GSEA ; gene set enrichment analysis ; HC ; heavy chain ; HMBA ; hexamethylene bisacetamide ; IgG1 ; human immunoglobulin G1 ; IRES ; internal ribosome entry site ; LC ; light chain ; mAb ; monoclonal antibody ; NaBu ; sodium butyrate ; PCA ; principal component analysis ; qP ; specific productivity ; RANK ; receptor activator of NF-Kappa B ; RNA- Seq ; next-generation RNA sequencing ; RPKM ; reads per kilobase of exon

刊名：Journal of Biotechnology

出版年：2015

2.Dihydrofolate Reductase Deficiency Due to a Homozygous DHFR Mutation Causes Megaloblastic Anemia and Cerebral Folate Deficiency Leading to Severe Neurologic Disease

作者：Holger Cario¹ ; ^{holger.cario@uniklinik-ulm.de} ; Desiré ; e E.C. Smith² ; Henk Blom² ; Nenad Blau³ ; ⁴ ; ⁵ ; Harald Bode¹ ; Karlheinz Holzmann⁶ ; Ulrich Pannicke⁷ ; Karl-Peter Hopfner⁸ ; Eva-Maria Rump⁹ ; Zuleya Ayric¹⁰ ; Elisabeth Kohne¹ ; Klaus-Michael Debatin¹ ; Yvo Smulders¹¹ ; Klaus Schwarz⁷ ; ⁹

刊名：The American Journal of Human Genetics

出版年：2011

3.Allosteric Communication in Dihydrofolate Reductase: Signaling Network and Pathways for Closed to Occluded Transition and Back

作者：Jie Chen ; Rux ; ra I. Dima ; D. Thirumalai

关键词：allosteric transition ; DHFR ; signaling network ; Brownian dynamics ; self-organized polymer model

刊名：Journal of Molecular Biology

出版年：2007

4.Peroxynitrite-mediated oxidation of the C85S/C152E mutant of dihydrofolate reductase from Escherichia coli: functional and structural effects

作者：Pucciarelli ; Stefania ; Spina ; Michele ; Montecchia ; Francesca ; Lupidi ; Giulio ; Eleuteri ; Anna Maria ; et. al.

关键词：Dihydrofolate reductase ; Peroxynitrite ; Oxidative damage ; Differential scanning calorimetry

刊名：Archives of Biochemistry and Biophysics

出版年：2005

5.Identification of a novel member of yeast mitochondrial Hsp70-associated motor and chaperone proteins that facilitates protein translocation across the inner membrane

作者：Yamamoto ; Hayashi ; Momose ; Takaki ; Yatsukawa ; Yoh-ichi ; Ohshima ; Chi?? ; Ishikawa ; Daigo ; et. al.

关键词：TOM ; the translocase of the outer mitochondrial membrane ; TIM ; the translocase of the inner mitochondrial membrane ; mtHsp70 ; mitochondrial Hsp70 ; MMC ; mitochondrial Hsp70-associated motor and chaperone ; FOA ; fluoroorotic acid ; PK ; proteinase K ; DHFR ; mous

刊名：FEBS Letters

出版年：2005

6.Serum- and protein-free media formulations for the Chinese hamster ovary cell line DUKXB11

作者：Schrö ; der ; Martin ; Matischak ; Kathrin ; Friedl ; Peter

关键词：ATIII ; antithrombin III ; CHO ; Chinese hamster ovary ; DHFR ; dihydrofolate reductase ; ELISA ; enzyme-linked immunosorbent assay ; FCS ; fetal calf serum ; l-LDH ; l-lactate dehydrogenase ; MTX ; methotrexate ; Chinese hamster ovary cells ; Serum-free medium ; Protein

刊名：Journal of Biotechnology

出版年：2004

7.Methotrexate and cytarabine inhibit progression of human lymphoma in NOD/SCID mice carrying a mutant dihydrofolate reductase and cytidine deaminase fusion gene

作者：Budak-Alpdogan ; Tulin ; Alpdogan ; Onder ; Banerjee ; Debabrata ; Wang ; Eunice ; Moore ; Malcolm A.S. ; et. al.

关键词：gene therapy ; drug resistance fusion gene ; human lymphoma ; posttransplant ; chemotherapy ; NOD-SCID mouse

刊名：Molecular Therapy

出版年：2004

8.Analysis in yeast of antimalaria drugs that target the dihydrofolate reductase of Plasmodium falciparum

作者：Wooden ; Jason M. ; Hartwell ; Leland H. ; Vasquez ; Brandi ; et. al.

关键词：Plasmodium falciparum ; Saccharomyces cerevisiae ; Malaria ; Antifolate ; Drug resistance ; DHFR ; dihydrofolate reductase ; Pf-DHFR ; DHFR derived from P. falciparum ; Sc-DHFR ; DHFR derived from S. cerevisiae ; D6 ; D6/Sierra Leone ; Hon ; Honduras 1 ; Mik ; Mikenga

刊名：Molecular and Biochemical Parasitology

出版年：1997

9.Overexpression and Large-Scale Purification of Recombinant Hamster Polymorphic ArylamineN-Acetyltransferase as a Dihydrofolate Reductase Fusion Protein

作者：Sticha ; Kristina R. K. ; Sieg ; Christine A. ; Bergstrom ; Carl P. ; Hanna ; Patrick E. ; Wagner ; Carston R.

刊名：Protein Expression and Purification

出版年：1997

10.In vitro and in vivo biological activities of a novel nonpolyglutamable anti-folate, MX-68

作者：Mihara ; Masahiko ; Urakawa ; Kazumi ; Takagi ; Nobuhiro ; Moriya ; Yoichiro ; Takeda ; Yasuhisa

关键词：MX-68 ; MTX ; Cell proliferation ; Polyglutamation ; Collagen-induced arthritis ; Mouse

刊名：Immunopharmacology

出版年：1996

按检索点细分(10)

关键词(1)

文摘(4)

按出版年细分(10)

2015年(1)

2011年(1)

2007年(1)

2005年(2)

2004年(2)

2000年及以前(3)