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在“
Elsevier电子期刊
”中,
命中:
4,157
条,耗时:0.1059505 秒
在所有数据库中总计命中:
6,639
条
1.
Structure
-guided development of covalent TAK1 inhibitors
作者:
Li Tan
a
;
b
;
j
;
Deepak Gurbani
c
;
d
;
j
;
Ellen L. Weisberg
e
;
f
;
John C. Hunter
c
;
d
;
Lianbo Li
c
;
d
;
Douglas S. Jones
g
;
h
;
Scott B. Ficarro
a
;
b
;
Samar Mowafy
a
;
b
;
i
;
Chun-Pong Tam
a
;
b
;
Suman Rao
a
;
b
;
g
;
Guangyan Du
a
;
b
;
James D. Griffin
e
;
f
;
Peter K. Sorger
g
;
Jarrod A. Marto
a
;
b
;
Kenneth D. Westover
c
;
d
;
Kenneth.Westover@UTSouthwestern.edu
;
Nathanael S. Gray
a
;
b
;
Nathanael_Gray@dfci.harvard.edu
关键词:
Structure
-based design
;
TAK1 kinase inhibitors
;
Covalent inhibitors
;
2
;
4-Disubstituted pyrimidine
;
Structure
-activity relationship
刊名:Bioorganic & Medicinal Chemistry
出版年:2017
2.
Noisy
signaling
in discrete time
作者:
Francesc Dilmé
;
fdilme@uni-bonn.de
关键词:
Dynamic noisy
signaling
;
Discrete time
;
Endogenous effort
刊名:Journal of Mathematical Economics
出版年:2017
3.
Apigenin protects myocardium by inhibiting the TGF-β
1
-mediated Smad
signaling
transduction pathway in acute myocardial infarcted rats
作者:
Ziliang Wang
a
;
b
;
Yan Chen
c
;
Dingli Xu
a
;
dinglixu@smu.edu.cn
关键词:
AMI
;
Apigenin
;
TGF-β1
signaling
;
Smad 7
刊名:Journal of Functional Foods
出版年:2017
4.
Crystal
Structure
of an LSD-Bound Human Serotonin Receptor
作者:
Daniel Wacker
1
;
9
;
dwacker@email.unc.edu
;
Sheng Wang
1
;
9
;
John D. McCorvy
1
;
9
;
Robin M. Betz
2
;
3
;
4
;
5
;
A.J. Venkatakrishnan
2
;
3
;
4
;
Anat Levit
6
;
Katherine Lansu
1
;
Zachary L. Schools
1
;
Tao Che
1
;
David E. Nichols
7
;
Brian K. Shoichet
6
;
Ron O. Dror
2
;
3
;
4
;
5
;
ron.dror@stanford.edu
;
Bryan L. Roth
1
;
7
;
8
;
10
;
bryan_roth@med.unc.edu
关键词:
GPCR
;
serotonin receptor
;
crystallography
;
structure
-function
;
hallucinogens
刊名:Cell
出版年:2017
5.
Regulating temporospatial dynamics of morphogen for
structure
formation of the lacrimal gland by chitosan biomaterials
作者:
Ya-Chuan Hsiao
a
;
b
;
c
;
Tsung-Lin Yang
a
;
d
;
e
;
yangtl@ntu.edu.tw" class="auth_mail" title="E-mail the corresponding author
关键词:
Lacrimal gland
;
Branching morphogenesis
;
Hepatocyte growth factor
;
Regeneration
;
Tissue engineering
刊名:Biomaterials
出版年:2017
6.
STRUCTURE
-FUNCTION STUDIES OF THE ALPHA PHEROMONE RECEPTOR FROM YEAST
作者:
Laura Marina Robles
a
;
Cé
;
sar Millá
;
n-Pacheco
c
;
Nina Pastor
b
;
Gabriel Del Rí
;
o
a
;
gdelrio@ifc.unam.mx
关键词:
alpha pheromone receptor
;
docking
;
molecular modeling
;
pheromone
;
Ste2p
刊名:TIP
出版年:2017
7.
Design and synthesis of formononetin-dithiocarbamate hybrids that inhibit growth and migration of PC-3 cells via MAPK/Wnt
signaling
pathways
作者:
Dong-Jun Fu
a
;
1
;
Li Zhang
a
;
1
;
Jian Song
a
;
1
;
Ruo-Wang Mao
a
;
Ruo-Han Zhao
a
;
Ying-Chao Liu
a
;
Yu-Hui Hou
a
;
Jia-Huan Li
a
;
Jia-Jia Yang
a
;
Cheng-Yun Jin
a
;
Ping Li
a
;
Xiao-Lin Zi
c
;
Hong-Min Liu
a
;
Sai-Yang Zhang
b
;
celeron16@163.com
;
Yan-Bing Zhang
a
;
zhangyb@zzu.edu.cn
关键词:
Formononetin
;
Dithiocarbamate
;
Growth
;
Migration
刊名:European Journal of Medicinal Chemistry
出版年:2017
8.
Estimation of the receptor-state affinity constants of ligands in functional studies using wild type and constitutively active mutant receptors: Implications for estimation of agonist bias
作者:
Frederick J. Ehlert
a
;
b
;
fjehlert@uci.edu
;
Richard S.L. Stein
b
关键词:
Receptor state affinity constants
;
Constitutive activity
;
Agonist bias
;
System bias
;
Monod-Wyman-Changeux model
;
Observed affinity
;
Efficacy
;
Receptor activation
;
Active state
;
Inactive state
刊名:Journal of Pharmacological and Toxicological Methods
出版年:2017
9.
The inhibitory activity of ginsenoside Rp4 in adenosine diphosphate-induced platelet aggregation
作者:
Young-Min Son
1
;
Da-Hye Jeong
1
;
Hwa-Jin Park
2
;
Man-Hee Rhee
1
;
rheemh@knu.ac.kr
关键词:
fibrinogen
;
ginsenoside Rp4
;
granule
;
MAPK
;
platelet aggregation
刊名:Journal of Ginseng Research
出版年:2017
10.
Pluripotent stem cell expansion and neural differentiation in 3-D scaffolds of tunable Poisson’s ratio
作者:
Yuanwei Yan
a
;
Yan Li
b
;
c
;
Liqing Song
a
;
Changchun Zeng
b
;
c
;
Yan Li
a
;
yli@eng.fsu.edu
关键词:
Pluripotent stem cell
;
Neural differentiation
;
Auxetic scaffold
;
Poisson&rsquo
;
s ratio
刊名:Acta Biomaterialia
出版年:2017
1
2
3
4
5
6
7
8
9
按检索点细分(4157)
题名(123)
关键词(92)
文摘(3276)
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