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Elsevier电子期刊(11)
ACS电子期刊(5)
在“
Elsevier电子期刊
”中,
命中:
11
条,耗时:0.0100216 秒
在所有数据库中总计命中:
16
条
1.
Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: Prime side chromane-containing inhibitors
作者:
Raymond A. Ng
;
Minghua Sun
;
Simeon
Bowers
;
Roy K. Hom
;
Gary D. Probst
;
Varghese John
;
Lawrence Y. Fang
;
Michel Maillard
;
Andrea Gailunas
;
Louis Brogley
;
R. Jeffrey Neitz
;
Jay S. Tung
;
Michael A. Pleiss
;
Andrei W. Konradi
;
Hing L. Sham
;
Michael S. Dappen
;
Marc Adler
;
Nanhua Yao
;
Wes Zmolek
;
David Nakamura
;
et al.
关键词:
Beta-secratase inhibitor
;
BACE-1
;
Alzheimer&rsquo
;
s disease
;
Cat-D
;
Chromane
;
Hydroxyethylamine
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2013
2.
Highly selective c-Jun N-terminal kinase (JNK) 2 and 3 inhibitors with in vitro CNS-like pharmacokinetic properties prevent neurodegeneration
作者:
Gary D. Probst
;
Simeon
Bowers
;
Jennifer M. Sealy
;
Anh P. Truong
;
Roy K. Hom
;
Robert A. Galemmo Jr.
;
Andrei W. Konradi
;
Hing L. Sham
;
David A. Quincy
;
Hu Pan
;
Nanhua Yao
;
May Lin
;
Gergley Tó
;
th
;
De
关键词:
JNK inhibitor
;
Selective
;
Kinase
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2011
3.
Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: Structure–activity relationship of the aryl region
作者:
Gary D. Probst
;
Simeon
Bowers
;
Jennifer M. Sealy
;
Brian Stupi
;
Darren Dressen
;
Barbara M. Jagodzinska
;
Jose Aquino
;
Andrea Gailunas
;
Anh P. Truong
;
Luke Tso
;
Ying-Zi Xu
;
Roy K. Hom
;
Varghese John
;
Jay
关键词:
Alzheimer’
;
s disease
;
Beta-secretase inhibitor
;
BACE-1
;
HEA
;
Hydroxyethylamine
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2010
4.
Design of an orally efficacious hydroxyethylamine (HEA) BACE-1 inhibitor in a preclinical animal model
作者:
Anh P. Truong
;
Gergley Tó
;
th
;
Gary D. Probst
;
Jennifer M. Sealy
;
Simeon
Bowers
;
David W.G. Wone
;
Darren Dressen
;
Roy K. Hom
;
Andrei W. Konradi
;
Hing L. Sham
;
Jing Wu
;
Brian T. Peterson
;
Lany Rusli
关键词:
BACE-1 inhibitor
;
Hydroxyethylamine (HEA)
;
Alzheimer’
;
s disease
;
Fluorine
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2010
5.
Design and synthesis of disubstituted thiophene and thiazole based inhibitors of JNK
作者:
Roy K. Hom
;
Simeon
Bowers
;
Jennifer M. Sealy
;
Anh P. Truong
;
Gary D. Probst
;
Martin L. Neitzel
;
R. Jeffrey Neitz
;
Larry Fang
;
Louis Brogley
;
Jing Wu
;
Andrei W. Konradi
;
Hing L. Sham
;
Gergely Tó
;
th
关键词:
JNK3
;
Kinase
;
Thiophene
;
c-Jun N-terminal kinase
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2010
6.
N-Bridged bicyclic sulfonamides as inhibitors of γ-secretase
作者:
Simeon
Bowers
;
Gary D. Probst
;
Anh P. Truong
;
Roy K. Hom
;
Andrei W. Konradi
;
Hing L. Sham
;
Albert W. Garofalo
;
Karina Wong
;
Erich Goldbach
;
Kevin P. Quinn
;
John-Michael Sauer
;
William Wallace
;
Lan Ngu
关键词:
Alzheimer’
;
s disease
;
γ
;
-Secretase inhibitor
;
Bicyclic sulfonamides
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2009
7.
Design, synthesis, and structure–activity relationship of novel orally efficacious pyrazole/sulfonamide based dihydroquinoline γ-secretase inhibitors
作者:
Anh P. Truong
;
Danielle L. Aubele
;
Gary D. Probst
;
Martin L. Neitzel
;
Chris M. Semko
;
Simeon
Bowers
;
Darren Dressen
;
Roy K. Hom
;
Andrei W. Konradi
;
Hing L. Sham
;
Albert W. Garofalo
;
Pamela S. Keim
;
Ji
关键词:
γ
;
-Secretase inhibitors
;
Alzheimer’
;
s disease
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2009
8.
Corrigendum to “Design, synthesis, and structure–activity relationship of novel orally efficacious pyrazole/sulfonamide based dihydroquinoline γ-secretase inhibitors” [Bioorg. Med. Chem. Lett. 19 (2009) 4920]
作者:
Anh P. Truong
;
Danielle L. Aubele
;
Gary D. Probst
;
Martin L. Neitzel
;
Chris M. Semko
;
Simeon
Bowers
;
Darren Dressen
;
Roy K. Hom
;
Andrei W. Konradi
;
Hing L. Sham
;
Albert W. Garofalo
;
Pamela S. Keim
;
Ji
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2010
9.
Biosynthetic studies on the α-glucosidase inhibitor acarbose: the chemical synthesis of isotopically labeled 2-
epi
-5-
epi
-valiolone analogs
作者:
Arakawa
;
Kenji
;
Bowers
;
Simeon
G.
;
Michels
;
Benjamin
;
Trin
;
Vu
;
Mahmud
;
Taifo
关键词:
2-epi-5-epi-Valiolone analogs
;
Acarbose biosynthesis
;
Valiolol
;
Valiolamine
刊名:Carbohydrate Research
出版年:2003
10.
Biosynthetic studies on the α-glucosidase inhibitor acarbose: the chemical synthesis of dTDP-4-amino-4,6-dideoxy-α-d-glucose
作者:
Bowers
;
Simeon
G.
;
Mahmud
;
Taifo
;
Floss
;
Heinz G.
关键词:
Acarbose biosynthesis
;
Aminodeoxy sugar
刊名:Carbohydrate Research
出版年:2002
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