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Springer电子图书(2)
NATURE电子期刊(3)
ACS电子期刊(7)
SpringerLink电子期刊(50)
Elsevier电子期刊(15)
在“
Elsevier电子期刊
”中,
命中:
15
条,耗时:小于0.01 秒
在所有数据库中总计命中:
77
条
1.
Novel trifluoromethylated 9-amino-3,4-dihydroacridin-1(2H)-ones act as covalent poisons of human
topoisomerase
IIα
作者:
Lorena Infante Lara
a
;
Alexis Sledge
d
;
Amine Laradji
d
;
Cosmas O. Okoro
d
;
cokoro@tnstate.edu
;
Neil Osheroff
a
;
b
;
c
;
neil.osheroff@vanderbilt.edu
关键词:
Acridin-1(2H)-ones
;
DNA
topoisomerase
IIα
;
Anticancer drugs
;
Covalent poison
;
DNA cleavage
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2017
2.
Fluorescein hydrazones: A series of novel non-intercalative
topoisomerase
IIα
catalytic inhibitors induce G1 arrest and apoptosis in breast and colon cancer cells
作者:
Mohammad Shahidul Islam
a
;
1
;
Seojeong Park
b
;
1
;
Chanju Song
b
;
Adnan A. Kadi
c
;
Youngjoo Kwon
b
;
ykwon@ewha.ac.kr
;
A.F.M. Motiur Rahman
c
;
afmrahman@ksu.edu.sa
关键词:
Fluorescein
;
Fluorescein hydrazones
;
Topoisomerase
IIα
catalytic inhibitor
;
Apoptosis
刊名:European Journal of Medicinal Chemistry
出版年:2017
3.
Synthesis and biological evaluation of naphthoquinone-coumarin conjugates as
topoisomerase
II inhibitors
作者:
Idaira Hueso-Falcó
;
n
a
;
Á
;
ngel Amesty
a
;
1
;
Laura Anaissi-Afonso
b
;
1
;
Isabel Lorenzo-Castrillejo
b
;
Fé
;
lix Machí
;
n
b
;
fmachin@funcanis.org
;
Ana Esté
;
vez-Braun
a
;
aestebra@ull.es
关键词:
2-Hydroxynaphthoquinone
;
4-Hydroxycoumarin
;
Privileged structures
;
Topoisomerase
II
;
ATPase
;
Docking
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2017
4.
Novel 2-aryl-4-(4′-hydroxyphenyl)-5H-indeno[1,2-b]pyridines as potent DNA non-intercalative
topoisomerase
catalytic inhibitors
作者:
Seojeong Park
a
;
1
;
Tara Man Kadayat
b
;
1
;
Kyu-Yeon Jun
a
;
Til Bahadur Thapa Magar
b
;
Ganesh Bist
b
;
Aarajana Shrestha
b
;
Eung-Seok Lee
b
;
eslee@yu.ac.kr
;
Youngjoo Kwon
a
;
ykwon@ewha.ac.kr
关键词:
Anticancer agents
;
2-Aryl-4-(4&prime
;
-hydroxyphenyl)-5H-indeno[1
;
2-b]pyridine
;
Antiproliferative activity
;
Docking study
;
Dual
topoisomerase
I and II inhibitors
刊名:European Journal of Medicinal Chemistry
出版年:2017
5.
A novel copper(II) complex identified as a potent drug against colorectal and breast cancer cells and as a poison inhibitor for human
topoisomerase
IIα
作者:
Shayna Sandhaus
a
;
Rosella Taylor
b
;
Tiffany Edwards
b
;
Alexis Huddleston
b
;
Ykeysha Wooten
b
;
Ramaiyer Venkatraman
c
;
Ralph T. Weber
d
;
Antonio Gonzá
;
lez-Sarrí
;
as
e
;
Patrick M. Martin
f
;
Patrice Cagle
f
;
Yuk-Ching Tse-Dinh
a
;
g
;
Stephen J. Beebe
h
;
Navindra Seeram
e
;
Alvin A. Holder
i
;
aholder@odu.edu" class="auth_mail" title="E-mail the corresponding author
关键词:
Thiosemicarbazones
;
Copper(II)
;
Human
topoisomerase
Iiα
;
Breast cancer
;
ESR spectroscopy
;
Cyclic voltammetry
刊名:Inorganic Chemistry Communications
出版年:2016
6.
Quinolino[3,4-b]quinoxalines and pyridazino[4,3-c]quinoline derivatives: Synthesis, inhibition of
topoisomerase
IIα
, G-quadruplex binding and cytotoxic properties
作者:
Fausta Palluotto
a
;
1
;
Alice Sosic
b
;
1
;
Odra Pinato
b
;
Grigoris Zoidis
c
;
Marco Catto
a
;
marco.catto@uniba.it" class="auth_mail" title="E-mail the corresponding author
;
Claudia Sissi
b
;
Barbara Gatto
b
;
Angelo Carotti
a
关键词:
Quinoline derivatives
;
Pyridazine derivatives
;
Topoisomerase
IIα
inhibitors
;
G-quadruplex stabilizers
;
Cytotoxic agents
刊名:European Journal of Medicinal Chemistry
出版年:2016
7.
T1 high-grade bladder carcinoma outcome: the role of p16,
topoisomerase
-
IIα
, survivin, and E-cadherin
作者:
Maria Rosaria Raspollini
;
MD
;
PhD
a
;
mariarosaria.raspollini@unifi.it" class="auth_mail" title="E-mail the corresponding author
;
Rafael J. Luque
;
MD
b
;
Carmen Luz Menendez
;
MD
c
;
Enrico Bollito
;
MD
d
;
Matteo Brunelli
;
MD
e
;
Guido Martignoni
;
MD
e
;
Rodolfo Montironi
;
MD
;
FRCPath
;
IFCAP
f
;
Liang Cheng
;
MD
g
;
Ana Blanca
;
MD
h
;
Gianna Baroni
;
BSc
a
;
Andrea Minervini
;
MD
;
PhD
i
;
Antonio Lopez-Beltran
;
MD
;
PhD
j
;
k
关键词:
Bladder cancer
;
Progression
;
T1
;
p16
;
Topoisomerase
-
IIα
;
Survivin
;
E-cadherin
刊名:Human Pathology
出版年:2016
8.
Design, synthesis,
topoisomerase
I & II inhibitory activity, antiproliferative activity, and structure-activity relationship study of pyrazoline derivatives: An ATP-competitive human
topoisomerase
IIα
catalytic inhibitor
作者:
Pervez Ahmad
a
;
&dagger
;
;
Hyunjung Woo
b
;
&dagger
;
;
Kyu-Yeon Jun
b
;
Adnan A. Kadi
a
;
Hatem A. Abdel-Aziz
a
;
c
;
Youngjoo Kwon
b
;
ykwon@ewha.ac.kr" class="auth_mail" title="E-mail the corresponding author
;
A.F.M. Motiur Rahman
a
;
afmrahman@ksu.edu.sa" class="auth_mail" title="E-mail the corresponding author
关键词:
Pyrazoline derivatives
;
Antiproliferative activity
;
Topoisomerase
;
ATP-competitive inhibitor
刊名:Bioorganic & Medicinal Chemistry
出版年:2016
9.
Synthesis and biological evaluation of imidazopyridinyl-1,3,4-oxadiazole conjugates as apoptosis inducers and
topoisomerase
IIα
inhibitors
作者:
A.V. Subba Rao
a
;
b
;
M.V.P.S. Vishnu Vardhan
a
;
N.V. Subba Reddy
a
;
T. Srinivasa Reddy
c
;
Siddiq Pasha Shaik
a
;
Chandrakant Bagul
d
;
Ahmed Kamal
a
;
b
;
c
;
d
;
ahmedkamal@iict.res.in" class="auth_mail" title="E-mail the corresponding author
关键词:
Imidazopyridine
;
Oxadiazole
;
Cytotoxicity
;
Topoisomerase
;
Molecular docking
刊名:Bioorganic Chemistry
出版年:2016
10.
Scaffold-hopping of bioactive flavonoids: Discovery of aryl-pyridopyrimidinones as potent anticancer agents that inhibit catalytic role of
topoisomerase
IIα
作者:
Garima Priyadarshani
a
;
1
;
Suyog Amrutkar
b
;
1
;
Anmada Nayak
c
;
Uttam C. Banerjee
b
;
Chanakya N. Kundu
c
;
Sankar K. Guchhait
a
;
skguchhait@niper.ac.in" class="auth_mail" title="E-mail the corresponding author
关键词:
Flavonoids
;
Pyrido[1
;
2-a]pyrimidin-4-ones
;
Scaffold-hopping
;
Human
topoisomerase
IIα
;
Anticancer agent
;
Drug discovery
刊名:European Journal of Medicinal Chemistry
出版年:2016
1
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