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Elsevier电子期刊(66)

在“Elsevier电子期刊”中，命中：66条，耗时：小于0.01 秒

在所有数据库中总计命中：66条

1.Alamethicin for using in bioavailability studies? - Re-evaluation of its effect

作者：Maren Vollmer ^{Maren.Vollmer@chemie.uni-hamburg.de} ; Mirko Klingebiel ^{mikl1710@kdwelt.de} ; Sascha Rohn ; ^{rohn@chemie.uni-hamburg.de} ; Ronald Maul ^{maul@chemie.uni-hamburg.de}

关键词：Clint ; intrinsic clearance ; Clint app. ; apparent intrinsic clearance ; DAD ; diod array detector ; DMSO ; dimethyl sulfoxide ; ER ; endoplasmic reticulum ; fu ; unbound fraction of a drug in the microsomal incubation mixture ; HPLC ; high performance liquid chromatography ; Km ; Michaelis-Menten constant ; P ; partition coefficient ; S ; substrate concentration ; UDP ; uridine diphosphate ; UDPGA ; uridine 5&prime ; -diphosphoglucuronic acid trisodium salt ; UGT ; UDP-glucuronosyltransferase ; v ; velocity ; Vmax ; maximal

刊名：Toxicology in Vitro

出版年：2017

2.Cremophor EL-based nanoemulsion enhances transcellular permeation of emodin through glucuronidation reduction in UGT1A1-overexpressing MDCKII cells

作者：Tianpeng Zhang^a ; ¹ ; Dong Dong^b ; ¹ ; Danyi Lu^a ; Shuai Wang^a ; Baojian Wu^a ; ^{bj.wu@hotmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：DMEM ; Dulbecco&rsquo ; s modified Eagle&rsquo ; s medium ; FBS ; fetal bovine serum ; SDS ; sodium dodecyl sulfonate ; MCT ; medium chain triglycerides ; MDCK1A1 cells ; UGT1A1-overexpressing MDCKII cells ; UDPGA ; uridine diphosphoglucuronic acid ; UGT ; UDP-glucuronosyltransferase ; EMO-NE ; emodin nanoemulsion ; TEM ; transmission electron microscopy ; EMO ; emodin ; EMO-G ; emodin glucuronide ; UPLC ; ultra performance liquid chromatography

刊名：International Journal of Pharmaceutics

出版年：2016

3.Activities of xenobiotic metabolizing enzymes in rat placenta and liver in vitro

作者：Eric Fabian^a ; ; Xinyi Wang^b ; Franziska Engel^a ; ; Hequn Li^b ; Robert Landsiedel^a ; Bennard van Ravenzwaay^a ; ^b ; ^{bennard.ravenzwaay@basf.com" class="auth_mail" title="E-mail the corresponding author}

关键词：ADH ; alcohol dehydrogenase ; ALDH ; aldehyde dehydrogenase ; BA ; benzydamine ; BA-Nox ; benzydamine-N-oxide ; BROD ; 7-benzylresorufin-O-dealkylase ; CYP ; cytochrome P450 ; DDT ; dithiothreitol ; EROD ; 7-ethylresorufin-O-dealkylase ; FMO ; flavin-containing monooxygenase ; GST ; glutathione S-transferase ; HBP ; 4-hydroxybiphenyl ; LOD ; limit of detection ; LOQ ; limit of quantification ; MUF ; 4-methylumbelliferone ; PBTK ; physiologically-based toxicokinetics ; PROD ; 7-pentylresorufin-O-dealkylase ; UDPGA ; UDP-glucuron

刊名：Toxicology in Vitro

出版年：2016

4.A novel method for the quantitation of gingerol glucuronides in human plasma or urine based on stable isotope dilution assays

作者：Carola Schoenknecht ; Gaby Andersen ; Peter Schieberle ; ^{peter.schieberle@lrz.tum.de" class="auth_mail" title="E-mail the corresponding author}

关键词：%CV ; coefficient of variation ; cmax ; maximal plasma concentration ; tmax ; the time to reach cmax ; AUC ; area under the curve ; kel ; terminal elimination rate constant ; t1/2 ; elimination half-life ; SIM ; selected-ion monitoring modus ; HSQC ; heteronuclear single quantum coherence ; HMBC ; heteronuclear multiple bond coherence ; NADPH ; reduced form of nicotinamide adenine dinucleotide phosphate ; SIDA ; stable isotope dilution assays ; UDPGA ; uridin-5&prime ; -diphosphoglucuronic acid

刊名：Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences

出版年：2016

5.Transcriptome association analysis identifies miR-375 as a major determinant of variable acetaminophen glucuronidation by human liver

作者：Ioannis Papageorgiou^a ; ^{johnp@vetmed.wsu.edu" class="auth_mail" title="E-mail the corresponding author} ; Marina Freytsis^b ; ^{Marina.Freytsis@tufts.edu" class="auth_mail" title="E-mail the corresponding author} ; Michael H. Court^a ; ^{michael.court@vetmed.wsu.edu" class="auth_mail" title="E-mail the corresponding author}

关键词：ALF ; acute liver failure ; NAPQI ; N-acetyl-p-benzoquinone imine ; UGT ; UDP-glucuronosyltransferase ; SULT ; sulfotransferase ; CYP ; cytochrome P450 ; 3&prime ; -UTR ; 3&prime ; -untranslated region ; SNP ; single nucleotide polymorphism ; miRNA ; microRNA ; UDPGA ; uridine diphosphate glucuronic acid ; qPCR ; quantitative real-time PCR ; AhR ; aryl hydrocarbon receptor ; MRE ; miRNA response element ; HNF1A ; hepatocyte nuclear factor 1-alpha ; HNF1B ; hepatocyte nuclear factor 1-beta ; Nrf2 ; nuclear factor erythroid 2-rel

刊名：Biochemical Pharmacology

出版年：2016

6.Absorption and metabolism characteristics of pristimerin as determined by a sensitive and reliable LC-MS/MS method

作者：Chuanhai Dong^a ; Chongde Xu^b ; Hui Liu^a ; ^c ; Shuna Xu^a ; Yunsheng Gao^c ; Jian Peng^a ; ^{JianPeng_KY@163.com" class="auth_mail" title="E-mail the corresponding author}

关键词：Pristimerin (PubChem CID ; 159516) ; Hydrocortisone (PubChem CID ; 5754) ; Glucose 6-phosphate (PubChem CID ; 5958) ; UDPGA (PubChem CID ; 17473) ; Verapamil (PubChem CID ; 62969) ; Lucifer yellow (PubChem CID ; 93367) ; 尾-nicotinamide adenine dinucleotide phosphate (PubChem CID ; 5884)

刊名：Fitoterapia

出版年：2015

7.Efflux transport of chrysin and apigenin sulfates in HEK293 cells overexpressing SULT1A3: The role of multidrug resistance-associated protein 4 (MRP4/ABCC4)

作者：Wan Li¹ ; Hua Sun¹ ; Xingwang Zhang ; Huan Wang ; Baojian Wu ; ^{bj.wu@hotmail.com" class="auth_mail" title="E-mail the corresponding author}

关键词：AS ; apigenin sulfate ; BCRP/Bcrp ; breast cancer resistance protein ; CYP ; cytochrome P450 ; CS ; chrysin sulfate ; DMEM ; Dulbecco&rsquo ; s modified Eagle&rsquo ; s medium ; FBS ; fetal bovine serum ; Km ; Michaelis&ndash ; Menten constant ; MRP/Mrp ; multidrug resistance-associated protein ; MS ; mass spectroscopy ; shRNA ; short hairpin RNA ; UDPGA ; uridine diphosphoglucuronic acid ; SULT ; sulfotransferases ; UPLC ; ultra performance liquid chromatography ; Vmax ; maximal velocity

刊名：Biochemical Pharmacology

出版年：2015

8.Glucuronidation of estrone and 16α-hydroxyestrone by human UGT enzymes: The key roles of UGT1A10 and UGT2B7

作者：Roope A. Kallionpä ; ä ; ¹ ; Erkka Jä ; rvinen ; Moshe Finel ; ^{moshe.finel@helsinki.fi" class="auth_mail" title="E-mail the corresponding author}

关键词：16α-OHE1 ; 16α-hydroxyestrone ; E1 ; estrone ; E2 ; 17β-estradiol ; HIM ; human intestine microsomes ; HLM ; human liver microsomes ; UDPGA ; uridine 5&prime ; -diphosphoglucuronic acid ; UGT ; UDP-glucuronosyltransferase

刊名：Journal of Steroid Biochemistry and Molecular Biology

出版年：2015

9.Metabolism studies of ifenprodil, a potent GluN2B receptor antagonist

作者：Evamaria Falck ; Frank Begrow ; Eugen Verspohl ; Bernhard W眉nsch

关键词：BSA ; bovine serum albumin ; CNS ; central nervous system ; COMT ; catechol-O-methyl transferase ; EIC ; extracted ion current ; NADPH ; nicotinamide adenine dinucleotide phosphate ; NMDA ; N-methyl-d-aspartate ; PAPS ; adenosine-3&prime ; -phosphate-5&prime ; -phosphosulfate lithium salt hydrate ; SAM ; S-(5&prime ; -adenosyl)-l-methionine iodide ; TIC ; total ion current ; UDPGA ; uridine 5&prime ; -diphosphoglucuronic acid trisodium salt

刊名：Journal of Pharmaceutical and Biomedical Analysis

出版年：25 January, 2014

10.Renal glucuronidation and multidrug resistance protein 2-/ multidrug resistance protein 4-mediated efflux of mycophenolic acid: interaction with cyclosporine and tacrolimus

作者：Azza A.K. El-Sheikh^a ; Jan B. Koenderink^b ; Alfons C. Wouterse^b ; Petra H.H. van den Broek^b ; Vivienne G.M. Verweij^b ; Rosalinde Masereeuw^b ; Frans G.M. Russel^b ; ^{Frans.Russel@radboudumc.nl" class="auth_mail}

关键词：CsA ; cyclosporine A ; FVB ; friend leukemia virus B strain ; HEK293 ; human embryonic kidney 293 ; HPLC ; high-performance liquid chromatography ; MMF ; mycophenolate mofetil ; MPA ; mycophenolic acid ; MPAG ; 7-hydroxy mycophenolic acid glucuronide ; MRP ; multidrug resistance protein ; MTT ; 3-[4 ; 5-dimethylthiazol-2-yl]-2 ; 5-diphenyltetrazolium bromide ; OAT ; organic anion transporter ; Tac ; tacrolimus ; UDPGA ; uridine 5&prime ; -diphosphoglucuronic acid ; UGT ; uridine diphosphoglucuronosyltransferase ; WH ; Wistar Ha

刊名：Translational Research

出版年：July 2014

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