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Elsevier电子期刊(9)
ACS电子期刊(3)
在“
Elsevier电子期刊
”中,
命中:
9
条,耗时:小于0.01 秒
在所有数据库中总计命中:
12
条
1.
Discovery of a novel class of highly potent inhibitors of the p53-MDM2 interaction by structure-based design starting from a conformational argument
作者:
Pascal Furet
;
pascal.furet@novartis.com" class="auth_mail" title="E-mail the corresponding author
;
Keiichi Masuya
;
Joerg Kallen
;
Thé
;
rè
;
se Stachyra-Valat
;
Stephan Ruetz
;
Vito
Guagnano
;
Philipp Holzer
;
Robert Mah
;
Stefan Stutz
;
Andrea Vaupel
;
Patrick Chè
;
ne
;
Sé
;
bastien Jeay
;
Achim Schlapbach
关键词:
p53&ndash
;
MDM2 inhibitors
;
Protein&ndash
;
protein interaction inhibitors
;
Anticancer agents
;
Structure-based design
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2016
2.
Increasing metabolic stability via the deuterium kinetic isotope effect: An example from a proline-amide-urea aminothiazole series of phosphatidylinositol-3 kinase alpha inhibitors
作者:
Robin A. Fairhurst
;
robin.fairhurst@novartis.com" class="auth_mail" title="E-mail the corresponding author
;
Giorgio Caravatti
;
Vito
Guagnano
;
Reiner Aichholz
;
Joachim Blanz
;
Francesca Blasco
;
Peter Wipfli
;
Christine Fritsch
;
Sauveur-Michel Maira
;
Christian Schnell
;
Frank H. Seiler
关键词:
Phosphatidylinositol-3 kinase alpha inhibitor
;
Deuterium kinetic isotope effect
;
Metabolism
;
Pharmacokinetics
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2016
3.
Discovery of NVP-BYL719 a potent and selective phosphatidylinositol-3 kinase alpha inhibitor selected for clinical evaluation
作者:
Pascal Furet
;
Vito
Guagnano
;
Robin A. Fairhurst
;
Patricia Imbach-Weese
;
Ian Bruce
;
Mark Knapp
;
Christine Fritsch
;
Francesca Blasco
;
Joachim Blanz
;
Reiner Aichholz
;
Jacques Hamon
;
Doriano Fabbro
;
Giorgio Caravatti
;
giorgio.caravatti@novartis.com
关键词:
PI3K inhibitors
;
Antitumor agent
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2013
4.
Corrigendum to ¡°Discovery of NVP-BYL719 a potent and selective phosphatidylinositol-3 kinase alpha inhibitor selected for clinical evaluation¡± [Bioorg. Med. Chem. Lett. 23 (2013) 3741-3748]
作者:
Pascal Furet
;
Vito
Guagnano
;
Robin A. Fairhurst
;
Patricia Imbach-Weese
;
Ian Bruce
;
Mark Knapp
;
Christine Fritsch
;
Francesca Blasco
;
Joachim Blanz
;
Reiner Aichholz
;
Jacques Hamon
;
Doriano Fabbro
;
Giorgio Caravatti
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2013
5.
Entry into a new class of protein kinase inhibitors by pseudo ring design
作者:
Pascal Furet
;
Giorgio Caravatti
;
Vito
Guagnano
;
Marc Lang
;
Thomas Meyer
;
Joseph Schoepfer
关键词:
Kinase
;
Scaffold morphing
;
Pseudo ring
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2008
6.
Novel β-lactam derivatives: Potent and selective inhibitors of the chymotrypsin-like activity of the human 20S proteasome
作者:
Patricia Imbach
;
Marc Lang
;
Carlos Garcí
;
a-Echeverrí
a ;
Vito
Guagnano
;
Maria Noorani
;
Johannes Roesel
;
Francis Bitsch
;
Grety Rihs
;
Pascal Furet
关键词:
Proteasome inhibitors
;
β
;
-Lactams
;
Covalent inhibitors
;
Antiproliferative agents
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2007
7.
Synthesis and biological evaluation of highly potent analogues of epothilones B and D
作者:
Altmann
;
Karl-Heinz
;
Bold
;
Guido
;
Caravatti
;
Giorgio
;
Flö
;
rsheimer
;
Andreas
;
Guagnano
;
Vito
;
et. al.
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2000
8.
Synthesis and biological evaluation of highly potent analogues of epothilones B and D
作者:
Altmann
;
Karl-Heinz
;
Bold
;
Guido
;
Caravatti
;
Giorgio
;
Flö
;
rsheimer
;
Andreas
;
Guagnano
;
Vito
;
et. al.
刊名:Bioorganic and Medicinal Chemistry Letters
出版年:2000
9.
Regioselective Ni(II)-assisted alkylation of 2-methoxy-5,6-dihydro-2H-pyran: a new route to 2-n-alkyl-5,6-dihydro-2H-pyrans
作者:
Guagnano
;
Vito
;
Lardicci
;
Luciano
;
Malanga
;
Corrado
;
Menicagli
;
Rita
刊名:Tetrahedron Letters
出版年:1998
1
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