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Elsevier电子期刊(253)
在“
Elsevier电子期刊
”中,
命中:
253
条,耗时:小于0.01 秒
在所有数据库中总计命中:
253
条
1.
Neuroprotective effects of N-adamantyl-4-methylthiazol-2-amine against amyloid β-induced oxidative stress in mouse hippocampus
作者:
Jiae Kim
a
;
Chang Hun Cho
a
;
Hoh-Gyu Hahn
b
;
Soo-Young Choi
c
;
Sung-Woo Cho
a
;
swcho@amc.seoul.kr
关键词:
Aβ
;
amyloidβ
;
AD
;
Alzheimer&rsquo
;
s disease
;
cPLA2
;
cytosolic phospholipase A2
;
DCF
;
DA 2&prime
;
7&prime
;
-dichlorofluorescin diacetate
;
CAT
;
catalase
;
DMSO
;
dimethyl-sulfoxide
;
EDTA
;
ethylenediaminetetraacetic acid
;
GPx
;
glutathione peroxidase
;
GSH
;
reduced glutathione
;
HO-1
;
heme oxygenase 1
;
IL-1β
;
Interleukin-1 beta
;
iNOS
;
including nitric oxide synthase
;
MDA
;
malondialdehyde
;
MMP-2
;
matrix metalloproteinase-2
;
Nrf2
;
nuclear factor-erythroid 2-related factor 2
;
ROS
;
reactive oxygen species
;
S
刊名:Brain Research Bulletin
出版年:2017
2.
Pathological α-synuclein exacerbates the progression of Parkinson’s disease through microglial activation
作者:
Qiu-Shuang Zhang
a
;
Yang Heng
a
;
Yu-He Yuan
a
;
yuanyuhe@imm.ac.cn
;
Nai-Hong Chen
a
;
b
;
chennh@imm.ac.cn
关键词:
AKT
;
protein kinase B
;
AP-1
;
activator protein-1
;
BV-2
;
immortalized murine microglia cell line
;
CD11b
;
cluster of differentiation 11b
;
CD36
;
cluster of differentiation 36
;
CD44
;
cluster of differentiation 44
;
CD68
;
cluster of differentiation 68
;
CNS
;
central nervous system
;
COX-2
;
cyclooxygenase-2
;
cPLA2
;
cytosolic phospholipase A2
;
EP2
;
prostaglandin E2 receptor subtype 2
;
ERK
;
extracellular regulated kinases
;
FcγRs
;
Fc gamma receptors
;
IKK
;
IκB kinase
;
IL-1β
;
interleukin-1-β
;
IL-6
;
interleuki
刊名:Toxicology Letters
出版年:2017
3.
Structure-activity relationship studies on 1-(2-oxopropyl)indole-5-carboxylic acids acting as inhibitors of cytosolic phospholipase A
2
α: Effect of substituents at the indole 3-position on activity, solubility, and metabolic stability
作者:
Martina Arnsmann
;
Walburga Hanekamp
;
Alwine Schulze Elfringhoff
;
Matthias Lehr
;
lehrm@uni-muenster.de
关键词:
Cytosolic phospholipase A2α
;
Inhibitors
;
Indole derivatives
;
Metabolic stability
;
Ketone reduction
;
Glucuronidation
;
Aqueous solubility
刊名:European Journal of Medicinal Chemistry
出版年:2017
4.
2-Oxoamides based on dipeptides as selective calcium-independent phospholipase A
2
inhibitors
作者:
Anneta Smyrniotou
a
;
Maroula G. Kokotou
b
;
c
;
Varnavas D. Mouchlis
c
;
Efrosini Barbayianni
b
;
George Kokotos
b
;
Edward A. Dennis
c
;
edennis@ucsd.edu
;
Violetta Constantinou-Kokotou
a
;
vikon@aua.gr
关键词:
Dipeptides
;
Inhibitors
;
Oxoamides
;
Phospholipase A2
;
Pseudodipeptides
刊名:Bioorganic & Medicinal Chemistry
出版年:2017
5.
UCN enhances TGF-beta-mediated mitoinhibition of VSMCs via counteracting TGF-beta-induced
cPLA2
expression and activation
作者:
Chao Zhu
;
Changchun Cao
;
Xiaofei Wang
;
Jie Yuan
;
Lai Jin
;
Shengnan Li
;
snli@njmu.edu.cn" class="auth_mail" title="E-mail the corresponding author
关键词:
Ast
;
astressin
;
cPLA2
;
cytosolic phospholipase A2
;
CRF
;
corticotrophin-releasing factor
;
CRFR
;
corticotrophin-releasing factor receptor
;
PYR
;
pyrrophenone
;
UCN
;
urocortin
;
mitoinhibition
;
mitosis inhibition
刊名:International Journal of Biochemistry and Cell Biology
出版年:2016
6.
Ketogenic diet change
cPLA2
/clusterin and autophagy related gene expression and correlate with cognitive deficits and hippocampal MFs sprouting following neonatal seizures
作者:
Hong Ni
a
;
nyr2000@yeah.net" class="auth_mail" title="E-mail the corresponding author
;
nhdoctor@163.com" class="auth_mail" title="E-mail the corresponding author
;
Dong-jing Zhao
a
;
Tian Tian
a
;
b
关键词:
Ketogenic diet
;
Cpla2
;
Clusterin
;
Autophagy
;
Neonatal seizure
刊名:Epilepsy Research
出版年:2016
7.
Caged ceramide 1-phosphate (C1P) analogs: Novel tools for studying C1P biology
作者:
Antonio Gomez-Muñ
;
oz
;
antonio.gomez@ehu.es" class="auth_mail" title="E-mail the corresponding author
;
Patricia Gangoiti
;
Io-Guané
;
Rivera
;
Natalia Presa
;
Ana Gomez-Larrauri
;
Marta Ordoñ
;
ez
关键词:
Akt (PKB)
;
protein kinase
;
B BHNB
;
4-bromo-5-hydroxy-2-nitrobenzhydryl
;
BMDM
;
bone marrow-derived macrophages
;
CerK
;
ceramide kinase
;
C1P
;
ceramide 1-phosphate
;
cPLA2
;
calcium-dependent cytosolic phospholipase 2
;
DECM
;
7-(N
;
N-diethylamino)coumarin
;
ERK
;
extracellularly regulated kinases
;
GLUT
;
glucose transporter
;
iNOS
;
inducible nitric oxide synthase
;
PKC
;
protein kinase C
;
PI3K
;
phosphatidylinositol 3-kinase
;
PTX
;
pertussis toxin
;
ROS
;
reacfive oxygen species
;
SMase
;
sphingomyelinase
;
SPT
;
ser
刊名:Chemistry and Physics of Lipids
出版年:2016
8.
Control of inflammatory responses by ceramide, sphingosine 1-phosphate and ceramide 1-phosphate
作者:
Antonio Gomez-Muñ
;
oz
a
;
antonio.gomez@ehu.es" class="auth_mail" title="E-mail the corresponding author
;
Natalia Presa
a
;
npretor@gmail.com" class="auth_mail" title="E-mail the corresponding author
;
Ana Gomez-Larrauri
b
;
ana.gomezlarrauri@osakidetza.net" class="auth_mail" title="E-mail the corresponding author
;
Io-Guané
;
Rivera
a
;
io_rivera@hotmail.com" class="auth_mail" title="E-mail the corresponding author
;
Miguel Trueba
a
;
miguel.trueba@ehu.es" class="auth_mail" title="E-mail the corresponding author
;
Marta Ordoñ
;
ez
a
;
marta.ordonez87@gmail.com" class="auth_mail" title="E-mail the corresponding author
关键词:
Akt (PKB)
;
protein kinase
;
CerK
;
ceramide kinase
;
C1P
;
ceramide 1-phosphate
;
cPLA2
;
calcium-dependent cytosolic phospholipase 2
;
ERK
;
extracellularly regulated kinases
;
iNOS
;
inducible nitric oxide synthase
;
PKC
;
protein kinase C
;
PI3K
;
phosphatidylinositol 3-kinase
;
ROS
;
reactive oxygen species
;
SMase
;
sphingomyelinase
;
SPT
;
serine palmitoyl transferase
刊名:Progress in Lipid Research
出版年:2016
9.
Off-target effect of the cPLA
2
α inhibitor pyrrophenone: Inhibition of calcium release from the endoplasmic reticulum
作者:
Bogeon Yun
a
;
HeeJung Lee
a
;
Heather Ewing
b
;
Michael H. Gelb
b
;
Christina C. Leslie
a
;
lesliec@njhealth.org" class="auth_mail" title="E-mail the corresponding author
关键词:
cPLA2
α
;
Calcium
;
Pyrrophenone
;
Endoplasmic reticulum
;
Mitochondria
刊名:Biochemical and Biophysical Research Communications
出版年:2016
10.
BRP-187: A potent inhibitor of leukotriene biosynthesis that acts through impeding the dynamic 5-lipoxygenase/5-lipoxygenase-activating protein (FLAP) complex assembly
作者:
Ulrike Garscha
a
;
1
;
ulrike.garscha@uni-jena.de" class="auth_mail" title="E-mail the corresponding author
;
Susanna Voelker
a
;
1
;
susanna.voelker@gmx.de" class="auth_mail" title="E-mail the corresponding author
;
Simona Pace
a
;
simona.pace@uni-jena.de" class="auth_mail" title="E-mail the corresponding author
;
Jana Gerstmeier
a
;
jana.gerstmeier@uni-jena.de" class="auth_mail" title="E-mail the corresponding author
;
Besa Emini
a
;
eminibesa@gmail.com" class="auth_mail" title="E-mail the corresponding author
;
Stefanie Liening
a
;
stefanie.liening@uni-jena.de" class="auth_mail" title="E-mail the corresponding author
;
Antonietta Rossi
b
;
antrossi@unina.it" class="auth_mail" title="E-mail the corresponding author
;
Christina Weinigel
c
;
christina.weinigel@med.uni-jena.de" class="auth_mail" title="E-mail the corresponding author
;
Silke Rummler
c
;
silke.rummler@med.uni-jena.de" class="auth_mail" title="E-mail the corresponding author
;
Ulrich S. Schubert
d
;
e
;
ulrich.schubert@uni-jena.de" class="auth_mail" title="E-mail the corresponding author
;
Gerhard K.E. Scriba
a
;
gerhard.scriba@uni-jena.de" class="auth_mail" title="E-mail the corresponding author
;
Erşan Ç
;
elikoğlu
f
;
ersancelikoglu@gmail.com" class="auth_mail" title="E-mail the corresponding author
;
Burcu Ç
;
alışkan
f
;
brcaliskan@gmail.com" class="auth_mail" title="E-mail the corresponding author
;
Erden Banoglu
f
;
banoglu@gazi.edu.tr" class="auth_mail" title="E-mail the corresponding author
;
Lidia Sautebin
b
;
sautebin@unina.it" class="auth_mail" title="E-mail the corresponding author
;
Oliver Werz
a
;
d
;
oliver.werz@uni-jena.de" class="auth_mail" title="E-mail the corresponding author
关键词:
5-LO
;
5-lipoxygenase
;
AA
;
arachidonic acid
;
COX
;
cyclooxygenase
;
cPLA2
;
cytosolic phospholipase A2
;
FLAP
;
5-lipoxygenase-activating protein
;
fMLP
;
N-formyl-methionyl-leucyl-phenylalanine
;
H(P)ETE
;
hydro(pero)oxyeicosatetraenoic acid
;
HHT
;
hydroxyheptadecatrienoic acid
;
IL
;
interleukin
;
LPS
;
lipopolysaccharide
;
LT
;
leukotriene
;
mPGES-1
;
microsomal prostaglandin E2 synthase 1
;
MPO
;
myeloperoxidase
;
PG
;
phosphate-buffered saline plus 1
;
mg/ml glucose
;
PGC
;
phosphate-buffered saline plus 1
刊名:Biochemical Pharmacology
出版年:2016
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