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Wiley电子期刊(27)
ProQuest学位论文(1)
Elsevier电子期刊(2377)
SpringerLink电子期刊(702)
NATURE电子期刊(38)
ACS电子期刊(117)
在“
Elsevier电子期刊
”中,
命中:
2,377
条,耗时:0.0339853 秒
在所有数据库中总计命中:
3,262
条
1.
Estimation of the receptor-state affinity constants of ligands in functional studies using wild type and
constitutively
active
mutant receptors: Implications for estimation of agonist bias
作者:
Frederick J. Ehlert
a
;
b
;
fjehlert@uci.edu
;
Richard S.L. Stein
b
关键词:
Receptor state affinity constants
;
Constitutive activity
;
Agonist bias
;
System bias
;
Monod-Wyman-Changeux model
;
Observed affinity
;
Efficacy
;
Receptor activation
;
Active
state
;
In
active
state
刊名:Journal of Pharmacological and Toxicological Methods
出版年:2017
2.
Constitutively
active
Stat5b signaling confers tolerogenic functions to dendritic cells of NOD mice and halts diabetes progression
作者:
Echarki Zerif
a
;
Aida Maalem
a
;
Simon Gaudreau
a
;
Chantal Guindi
a
;
Muhammad Ramzan
a
;
Steeve Vé
;
roneau
a
;
Denis Gris
a
;
Jana Stankova
a
;
Marek Rola-Pleszczynski
a
;
Walid Mourad
b
;
Gilles Dupuis
c
;
Abdelaziz Amrani
a
;
Abdelaziz.Amrani@USherbrooke.ca
关键词:
DCs
;
Dendritic cells
;
Stat5
;
Signal Transducer and Activator of Transcription 5
;
Tregs
;
regulatory T cells
;
NOD
;
nonobese diabetic
;
T1D
;
type 1 diabetes
刊名:Journal of Autoimmunity
出版年:2017
3.
C-terminally truncated
constitutively
active
androgen receptor variants and their biologic and clinical significance in castration-resistant prostate cancer
作者:
Anca Azoitei
a
;
Axel S. Merseburger
b
;
Beate Godau
b
;
M. Raschid Hoda
b
;
Evi Schmid
c
;
Marcus V. Cronauer
b
;
marcus.cronauer@uksh.de
关键词:
aa
;
amino-acids
;
ADT
;
androgen deprivation therapy
;
AR
;
androgen receptor
;
ARΔLBD
;
androgen receptor lacking a functional ligand binding domain
;
AR-V
;
AR splice variant
;
BET
;
bromodomain and extra-terminal
;
CE
;
cryptic exon
;
CRPC
;
castration-resistant prostate cancer
;
CTC
;
circulating tumor cell
;
CTD
;
carboxy-terminal domain
;
DBD
;
DNA-binding domain
;
EMT
;
epithelial-mesenchymal transition
;
FFPE
;
formalin-fixed paraffin-embedded
;
HR
;
hinge region
;
I
;
intron
;
IF
;
immunofluorescence
;
IGF-1
;
insulin
刊名:The Journal of Steroid Biochemistry and Molecular Biology
出版年:2017
4.
RhoA GTPase oxidation stimulates cell proliferation via nuclear factor-κB activation
作者:
Jae-Gyu Kim
a
;
Hyung-Joo Kwon
b
;
c
;
Guang Wu
c
;
Yohan Park
a
;
Jae-Yong Lee
a
;
d
;
Jaebong Kim
a
;
d
;
Sung-Chan Kim
a
;
d
;
Myoen Choe
e
;
Seung Goo Kang
f
;
Goo-Young Seo
g
;
Pyeung-Hyeun Kim
g
;
Jae-Bong Park
a
;
c
;
d
;
jbpark@hallym.ac.kr
关键词:
CA
;
constitutively
active
;
DMEM
;
Dulbecco's modified Eagle's medium
;
DN
;
dominant negative
;
GAP
;
GTPase activating protein
;
GAPDH
;
glyceraldehyde-3-phosphate dehydrogenase
;
GDF
;
GDI displacement factor
;
GDI
;
guanine nucleotide dissociation inhibitor
;
GEF
;
guanine nucleotide exchange factor
;
GSH
;
glutathione
;
Rhotekin-RBD
;
Rhotekin Rho-binding domain
;
ROCK
;
Rho-dependent coiled-coil kinase
;
ROS
;
re
active
oxygen species
;
WT
;
wild-type
;
NF-κB
;
nuclear factor-κB
;
IκB
;
inhibitor of NF-κB
;
IKK
;
IκB ki
刊名:Free Radical Biology and Medicine
出版年:2017
5.
Claudin-5, -7, and -18 suppress proliferation mediated by inhibition of phosphorylation of Akt in human lung squamous cell carcinoma
作者:
Risa Akizuki
;
Shun Shimobaba
;
Toshiyuki Matsunaga
;
Satoshi Endo
;
Akira Ikari
;
ikari@gifu-pu.ac.jp
关键词:
CLDNs
;
claudins
;
CA
;
constitutively
active
;
DAPI
;
4&prime
;
6-diamidino-2-phenylindole
;
DN
;
dominant negative
;
EGFR
;
epidermal growth factor receptor
;
ERK
;
extracellular signal-regulated kinase
;
LDH
;
lactate dehydrogenase
;
MAP
;
mitogen-activated protein
;
NSCLC
;
non-small cell lung cancer
;
PCR
;
polymerase chain reaction
;
PDK1
;
3-phosphoinositide-dependent protein kinase-1
;
PI
;
propidium iodide
;
PI3K
;
phosphatidylinositol-3 kinase
;
PKA
;
protein kinase A
;
SCLC
;
small cell lung cancer
;
SDS-PAGE
;
sodi
刊名:Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
出版年:2017
6.
Lessons from tissue compartment-specific analysis of androgen receptor alterations in prostate cancer
作者:
Mark Daniel
a
;
b
;
Scott M. Dehm
b
;
c
;
d
;
dehm@umn.edu
关键词:
LHRH
;
luteinizing hormone releasing hormone
;
ADT
;
androgen depletion therapy
;
CRPC
;
castration-resistant prostate cancer
;
CYP17
;
cytochrome P450 c17
;
MR
;
mineralocorticoid receptor
;
ER
;
estrogen receptor
;
PR
;
progestins receptor
;
GR
;
glucocorticoid receptor
;
NTD
;
NH2-terminal domain
;
AF-1
;
activation function 1
;
LBD
;
ligand bind domain
;
ARE
;
androgen response element
;
RIP
;
RNA co-immunoprecipitation
;
NCOA
;
nuclear receptor coactivator
;
NCOR
;
nuclear receptor corepressor
;
CTC
;
circulating tumor c
刊名:The Journal of Steroid Biochemistry and Molecular Biology
出版年:2017
7.
Insights into ligand stimulation effects on gastro-intestinal stromal tumors signalling
作者:
Christelle Bahlawane
a
;
christelle.bahlawane@uni.lu
;
Martine Schmitz
a
;
Elisabeth Letellier
a
;
Karthik Arumugam
b
;
Nathalie Nicot
c
;
Petr V. Nazarov
c
;
Serge Haan
a
关键词:
c-KIT
;
PDGFRα
;
MAPK
;
PI3K
;
Gastro-intestinal stromal tumors
;
PD0325901
;
stem cell factor
刊名:Cellular Signalling
出版年:2017
8.
The phosphatidyl inositol 3 kinase pathway does not suppress activation of the ARF and BIM genes by deregulated E2F1 activity
作者:
Kenta Kurayoshi
a
;
Junko Okuno
a
;
Eiko Ozono
b
;
Ritsuko Iwanaga
c
;
Andrew P. Bradford
d
;
Kazuyuki Kugawa
a
;
Keigo Araki
a
;
Kiyoshi Ohtani
a
;
btm88939@kwansei.ac.jp
关键词:
E2F
;
RB
;
PI3K
;
Apoptosis
;
Gene regulation
刊名:Biochemical and Biophysical Research Communications
出版年:2017
9.
Maternal diabetes and high glucose in vitro trigger Sca1
+
cardiac progenitor cell apoptosis through FoxO3a
作者:
Penghua Yang
a
;
1
;
Wendy W. Yang
b
;
1
;
Xi Chen
a
;
Sunjay Kaushal
b
;
Daoyin Dong
a
;
Wei-Bin Shen
a
;
wshen@fpi.umaryland.edu
关键词:
Sca1+ cardiac progenitor cells
;
Maternal diabetes
;
Diabetic embryopathy
;
Apoptosis
;
FoxO3a
;
High glucose
刊名:Biochemical and Biophysical Research Communications
出版年:2017
10.
Analytical Validation of Androgen Receptor Splice Variant 7 Detection in a Clinical Laboratory Improvement Amendments (CLIA) Laboratory Setting
作者:
Parvez M. Lokhandwala
&lowast
;
;
Stacy L. Riel
&lowast
;
;
Lisa Haley
&lowast
;
;
Changxue Lu
&dagger
;
;
&Dagger
;
;
Yan Chen
&dagger
;
;
&Dagger
;
;
John Silberstein
&dagger
;
;
&Dagger
;
;
Yezi Zhu
&dagger
;
;
&Dagger
;
;
Gang Zheng
&lowast
;
;
Ming-Tseh Lin
&lowast
;
;
Christopher D. Gocke
&lowast
;
;
§
;
;
Alan W. Partin
&dagger
;
;
&Dagger
;
;
Emmanuel S. Antonarakis
&dagger
;
;
&Dagger
;
;
§
;
;
Jun Luo
&dagger
;
;
&Dagger
;
;
§
;
;
jluo2@jhmi.edu
;
James R. Eshleman
&lowast
;
;
§
;
;
jeshlem@jhmi.edu
刊名:The Journal of Molecular Diagnostics
出版年:2017
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