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内部出版物
Wiley电子期刊(6)
SpringerLink电子期刊(95)
Elsevier电子期刊(148)
ACS电子期刊(22)
在“
Elsevier电子期刊
”中,
命中:
148
条,耗时:小于0.01 秒
在所有数据库中总计命中:
271
条
1.
Comparison of catalytic and inhibitory properties in human drug-metabolizing
cytochrome
P450
3A4 and
3A5
for various compounds including endogenous steroid hormones and azole antifungals by molecular docking simulation
作者:
Toshiro Niwa
1
;
Norie Murayama
2
;
Yurie Imagawa
1
;
Hiroshi Yamazaki
2
刊名:Drug Metabolism and Pharmacokinetics
出版年:2017
2.
Multiple modes of inhibition of human
cytochrome
P450
2J2 by dronedarone, amiodarone and their active metabolites
作者:
Aneesh Karkhanis
a
;
Hui Yuan Lam
a
;
Gopalakrishnan Venkatesan
a
;
Siew Kwan Koh
b
;
Christina Li Lin Chai
a
;
Lei Zhou
b
;
Yanjun Hong
a
;
Pipin Kojodjojo
c
;
Eric Chun Yong Chan
a
;
phaccye@nus.edu.sg" class="auth_mail" title="E-mail the corresponding author
关键词:
AA
;
arachidonic acid
;
ACN
;
acetonitrile
;
AF
;
atrial fibrillation
;
CYP2D6
;
cytochrome
P450
2D6
;
CYP2J2
;
cytochrome
P450
2J2
;
CYP3A4
;
cytochrome
P450
3A4
;
CYP
3A5
;
cytochrome
P450
3A5
;
DDI
;
drug&ndash
;
drug interaction
;
EET
;
epoxyeicosatrienoic acid
;
GSH
;
glutathione
;
k
;
intrinsic elimination rate constant
;
Ki
;
reversible inhibition constant
;
KI
;
inactivator concentration at half-maximum inactivation rate constant
;
kinact
;
maximum inactivation rate constant
;
Km
;
Michaelis&ndash
;
Menten constant
;
Kobs
刊名:Biochemical Pharmacology
出版年:2016
3.
Lycopene protects against atrazine-induced hepatotoxicity through modifications of
cytochrome
P450
enzyme system in microsomes
作者:
Jun Xia
a
;
1
;
Jia Lin
a
;
1
;
Shi-Yong Zhu
a
;
1
;
Zheng-Hai Du
a
;
Jing-Ao Guo
a
;
Zi-Xuan Han
a
;
Jin-Long Li
a
;
Jinlongli@neau.edu.cn" class="auth_mail" title="E-mail the corresponding author
;
Ying Zhang
b
;
zhangyinghr@hotmail.com" class="auth_mail" title="E-mail the corresponding author
关键词:
Atrazine
;
Lycopene
;
Cytochrome
P450
s
;
Hepatic microsome
;
Transcriptional regulation
刊名:Experimental and Toxicologic Pathology
出版年:2016
4.
Gene polymorphisms and contents of
cytochrome
P450
s have only limited effects on metabolic activities in human liver microsomes
作者:
Na Gao
1
;
Xin Tian
1
;
Yan Fang
;
Jun Zhou
;
Haifeng Zhang
;
Qiang Wen
;
Linjing Jia
;
Jie Gao
;
Bao Sun
;
Jingyao Wei
;
Yunfei Zhang
;
Mingzhu Cui
;
Hailing Qiao
;
qiaohl@zzu.edu.cn" class="auth_mail" title="E-mail the corresponding author
关键词:
Cytochrome
P450
;
Drug metabolism
;
Gene polymorphism
;
Protein content
;
Individual variations
刊名:European Journal of Pharmaceutical Sciences
出版年:2016
5.
Successful treatment with afatinib after grade 3 hepatotoxicity induced by both gefitinib and erlotinib in EGFR mutation-positive non-small cell lung cancer
作者:
Yoshitaka Zenke
;
Shigeki Umemura
;
sumemura@east.ncc.go.jp" class="auth_mail" title="E-mail the corresponding author
;
ume-fuji@nifty.com" class="auth_mail" title="E-mail the corresponding author
;
Eri Sugiyama
;
Keisuke Kirita
;
Shingo Matsumoto
;
Kiyotaka Yoh
;
Seiji Niho
;
Hironobu Ohmatsu
;
Koichi Goto
关键词:
AUC
;
area under the curve
;
CYP
;
cytochrome
p450
enzymes
;
CYP
3A5
;
cytochrome
p450
3A5
;
EGFR
;
epidermal growth factor receptor gene
;
L858R
;
leucine 858 to arginine
;
PM
;
poor metabolizer
;
SNPs
;
single nucleotide polymorphisms
;
TKI
;
tyrosine kinase inhibitor
;
UGT1A1
;
uridine diphosphate glucuronosyltransferase (UGT) isoform 1A1
刊名:Lung Cancer
出版年:2016
6.
CYP gene expressions in obesity-associated metabolic syndrome
作者:
Suzan Tabur
a
;
suzan2471@yahoo.com.tr" class="auth_mail" title="E-mail the corresponding author
;
Serdar Oztuzcu
b
;
Elif Oguz
c
;
Seniz Demiryü
;
rek
d
;
Hasan Dagli
b
;
Belgin Alasehirli
e
;
Mesut Ozkaya
a
;
Abdullah T. Demiryü
;
rek
e
关键词:
Cytochrome
P450
;
Gene expression
;
Metabolic syndrome
;
Obesity
;
Polymerase chain reaction
刊名:Obesity Research & Clinical Practice
出版年:2016
7.
Is toxicity of PMMA (paramethoxymethamphetamine) associated with
cytochrome
P450
pharmacogenetics?
作者:
Merete Vevelstad
a
;
merete.vevelstad@fhi.no" class="auth_mail" title="E-mail the corresponding author
;
Elisabeth Leere Ø
;
iestad
a
;
b
;
elisabeth.oiestad@fhi.no" class="auth_mail" title="E-mail the corresponding author
;
Sara Bremer
c
;
sbremer@ous-hf.no" class="auth_mail" title="E-mail the corresponding author
;
Inger Lise Bogen
a
;
inger.lise.bogen@fhi.no" class="auth_mail" title="E-mail the corresponding author
;
Anna-Lena Zackrisson
d
;
anna-lena.zackrisson@rmv.se" class="auth_mail" title="E-mail the corresponding author
;
Marianne Arnestad
a
;
e
;
marianne.arnestad@fhi.no" class="auth_mail" title="E-mail the corresponding author
关键词:
PMMA
;
Paramethoxymethamphetamine
;
4-Methoxymethamphetamine
;
CYP2D6 pharmacogenetics
;
Designer drugs
;
Forensic toxicology
刊名:Forensic Science International
出版年:2016
8.
Meclizine, a pregnane X receptor agonist, is a direct inhibitor and mechanism-based inactivator of human
cytochrome
P450
3A
作者:
Winnie Yin Bing Foo
a
;
winnie_foo@u.nus.edu" class="auth_mail" title="E-mail the corresponding author
;
Hwee Ying Tay
a
;
a0083608@u.nus.edu" class="auth_mail" title="E-mail the corresponding author
;
Eric Chun Yong Chan
a
;
phaccye@nus.edu.sg" class="auth_mail" title="E-mail the corresponding author
;
Aik Jiang Lau
a
;
b
;
aikjiang.lau@nus.edu.sg" class="auth_mail" title="E-mail the corresponding author
关键词:
Meclizine dihydrochloride monohydrate (PubChem CID
;
173612)
;
Norchlorcyclizine (PubChem CID
;
9340)
;
6尾-Hydroxytestosterone (PubChem CID
;
65543)
;
Testosterone (PubChem CID
;
6013)
;
Prednisolone (PubChem CID
;
5755)
;
Ketoconazole (PubChem CID
;
456201)
;
Erythromycin (PubChem CID
;
12560)
;
Glutathione (PubChem CID
;
124886)
;
N-acetylcysteine (PubChem CID
;
12035)
刊名:Biochemical Pharmacology
出版年:2015
9.
Cytochrome
P450
enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation
作者:
Ulrich M. Zanger
;
uli.zanger@ikp-stuttgart.de
;
Matthias Schwab
关键词:
Biotransformation
;
Cytochrome
P450
monooxygenase
;
NADPH
;
cytochrome
P450
reductase
;
Pharmacogenetics
;
Polymorphism
;
Xenobiotic
刊名:Pharmacology and Therapeutics
出版年:2013
10.
Reduced Variability of Tacrolimus Trough Level in Once-Daily Tacrolimus-Based Taiwanese Kidney Transplant Recipients With High-Expressive Genotype of
Cytochrome
P450
3A5
作者:
M.-J. Wu
a
;
e
;
f
;
g
;
h
;
wmj530@gmail.com" class="auth_mail
;
C.-H. Chang
j
;
C.-Y. Cheng
b
;
K.-H. Shu
a
;
e
;
C.-H. Chen
a
;
f
;
C.-H. Cheng
a
;
e
;
T.-M. Yu
a
;
f
;
Y.-W. Chuang
a
;
f
;
S.-T. Huang
a
;
f
;
S.-F. Tsai
a
;
h
;
H.-C. Ho
c
;
J.-R. Li
c
;
Y.-N. Shiu
i
;
Y.-C. Fu
d
;
j
刊名:Transplantation Proceedings
出版年:March, 2014
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