设为首页
收藏本站
网站地图
|
English
|
公务邮箱
About the library
Background
History
Leadership
Organization
Readers' Guide
Opening Hours
Collections
Help Via Email
Publications
Electronic Information Resources
常用资源
电子图书
期刊论文
学位会议
外文资源
特色专题
内部出版物
Wiley电子期刊(4)
SpringerLink电子期刊(13)
Elsevier电子期刊(65)
Springer电子图书(2)
NATURE电子期刊(4)
ACS电子期刊(23)
在“
Elsevier电子期刊
”中,
命中:
65
条,耗时:0.0689363 秒
在所有数据库中总计命中:
111
条
1.
Characterization of aminoacyl-tRNA synthetase stability and substrate interaction by
differential
scanning
fluorimetry
作者:
Jamie A. Abbott
a
;
Jamie.Abbott@uvm.edu
;
Nathan M. Livingston
a
;
Shawn B. Egri
a
;
Ethan Guth
b
;
Christopher S. Francklyn
a
;
Christopher.Francklyn@uvm.edu
关键词:
Differential
scanning
fluorimetry
;
Aminoacyl-tRNA synthetase
;
Histidyl-tRNA synthetase
;
SYPRO Orange
;
tRNA
;
Amino acid
刊名:Methods
出版年:2017
2.
Diversity selection, screening and quantitative structure-activity relationships of osmolyte-like additive effects on the thermal stability of a monoclonal antibody
作者:
Olubukayo-Opeyemi Oyetayo
a
;
oyetayophdhbc@gmail.com
;
Oscar Mé
;
ndez-Lucio
b
;
Andreas Bender
b
;
Hans Kiefer
a
关键词:
mAb
;
Monoclonal antibody
;
MOE
;
Molecular Operating Environment
;
MDS
;
Multi-dimensional scaling
;
QSAR
;
Quantitative structure&ndash
;
activity relationship
;
DSC
;
Differential
scanning
calorimetry
;
DSF
;
Differential
scanning
fluorimetry
;
DMSO
;
Dimethyl sulfoxide
;
NaOH
;
Sodium hydroxide
;
HCl
;
Hydrochloric acid
;
LOO-CV
;
Leave-one-out cross-validation
;
PCA
;
Principal components analysis
;
PLS
;
Partial least squares
;
TMAO
;
Trimethylamine N-oxide
;
Tm
;
Melting temperature
;
TS potency
;
Thermal stabilization
刊名:European Journal of Pharmaceutical Sciences
出版年:2017
3.
Interdomain interactions rearrangements control the reaction steps of a thermostable DNA alkyltransferase
作者:
Castrese Morrone
a
;
1
;
Riccardo Miggiano
b
;
1
;
Mario Serpe
a
;
Alberto Massarotti
b
;
Anna Valenti
a
;
Giovanni del Monaco
a
;
Mosè
;
Rossi
a
;
Franca Rossi
b
;
Menico Rizzi
b
;
Giuseppe Perugino
a
;
giuseppe.perugino@ibbr.cnr.it
;
Maria Ciaramella
a
;
maria.ciaramella@ibbr.cnr.it
关键词:
BG-VG
;
SNAP-Vista Green&trade
;
substrate
;
Cter
;
C-terminal domain
;
DDMP
;
Difference Distance Matrix Plot
;
dsDNAm
;
O6-methyl-guanine-containing double-strand DNA
;
DSF
;
Differential
Scanning
Fluorimetry
;
hAGT
;
human AGT
;
MD
;
molecular dynamics
;
Nter
;
N-terminal domain
;
O6-BG
;
O6-benzyl-guanine
;
O6-MG
;
O6-methyl-guanine
;
RMSD
;
root-mean-square deviation
;
SsOGT
;
S. solfataricus O6-alkyl-guanine-DNA-alkyl-transferase
;
SsOGTm
;
methylated SsOGT
刊名:Biochimica et Biophysica Acta (BBA) - General Subjects
出版年:2017
4.
An effective thiol-reactive probe for
differential
scanning
fluorimetry
with a standard real-time polymerase chain reaction device
作者:
Lukas Hofmann
;
lxh278@case.edu" class="auth_mail" title="E-mail the corresponding author
;
Sahil Gulati
;
Avery Sears
;
Phoebe L. Stewart
;
Krzysztof Palczewski
;
kxp65@case.edu" class="auth_mail" title="E-mail the corresponding author
关键词:
Differential
scanning
fluorimetry
;
Standard RT&ndash
;
PCR device
;
Thiol-reactive fluorescent probe
;
BODIPY FL l-cystine
;
Membrane proteins
;
High-throughput assay
刊名:Analytical Biochemistry
出版年:2016
5.
Native denaturation
differential
scanning
fluorimetry
: Determining the effect of urea using a quantitative real-time thermocycler
作者:
Christine L. Childers
;
Stuart R. Green
;
Neal J. Dawson
;
Kenneth B. Storey
;
kenneth_storey@carleton.ca" class="auth_mail" title="E-mail the corresponding author
关键词:
Differential
scanning
fluorimetry
;
Enzyme kinetics
;
Enzyme stability
;
Urea
;
Native denaturation
;
Lactate dehydrogenase
刊名:Analytical Biochemistry
出版年:2016
6.
Differential
scanning
fluorimetry
based assessments of the thermal and kinetic stability of peptide-MHC complexes
作者:
Lance M. Hellman
a
;
Liusong Yin
b
;
Yuan Wang
a
;
Sydney J. Blevins
a
;
Timothy P. Riley
a
;
Orrin S. Belden
a
;
Timothy T. Spear
c
;
Michael I. Nishimura
c
;
Lawrence J. Stern
b
;
d
;
Brian M. Baker
a
;
brian-baker@nd.edu" class="auth_mail" title="E-mail the corresponding author
关键词:
DSF
;
differential
scanning
fluorimetry
;
Tm
;
melting temperature
;
CD
;
circular dichroism
刊名:Journal of Immunological Methods
出版年:2016
7.
Novel small molecule binders of human N-glycanase 1, a key player in the endoplasmic reticulum associated degradation pathway
作者:
Bharath Srinivasan
bharath.srinivasan@biology.gatech.edu" class="auth_mail" title="E-mail the corresponding author
;
Hongyi Zhou
;
Sreyoshi Mitra
;
Jeffrey Skolnick
;
skolnick@gatech.edu" class="auth_mail" title="E-mail the corresponding author
关键词:
NGLY1
;
N-glycanase
;
ER
;
endoplasmic reticulum
;
ERAD
;
endoplasmic reticulum associated degradation
;
SDS&ndash
;
PAGE
;
sodium dodecyl sulfate polyacrylamide gel electrophoresis
;
TSA
;
thermal shift assay
;
DSF
;
differential
scanning
fluorimetry
刊名:Bioorganic & Medicinal Chemistry
出版年:2016
8.
Reversible NaCl-induced aggregation of a monoclonal antibody at low pH: Characterization of aggregates and factors affecting aggregation
作者:
Fabian Bickel
a
;
b
;
bickel@hochschule-bc.de" class="auth_mail" title="E-mail the corresponding author
;
Eva Maria Herold
a
;
Alba Signes
a
;
Stefan Romeijn
c
;
Wim Jiskoot
c
;
Hans Kiefer
a
关键词:
A280
;
absorbance at 280
;
nm
;
A340
;
absorbance at 340
;
nm
;
AI
;
aggregation index
;
ANS
;
8-anilino-1-naphthalenesulfonic acid
;
CD
;
circular dichroism
;
DSF
;
differential
scanning
fluorimetry
;
ECD
;
equivalent circular diameter
;
FIM
;
flow imaging microscopy
;
FTIR
;
Fourier transform infrared spectroscopy
;
IgG
;
immunoglobulin G
;
mAb1
;
monoclonal antibody 1
;
NaCl
;
sodium chloride
;
NTA
;
nanoparticle tracking analysis
;
SE-HPLC
;
size-exclusion high performance liquid chromatography
;
TM
;
melting temp
刊名:European Journal of Pharmaceutics and Biopharmaceutics
出版年:2016
9.
Engineering another class of anti-tubercular lead: Hit to lead optimization of an intriguing class of gyrase ATPase inhibitors
作者:
Variam Ullas Jeankumar
1
;
Rudraraju Srilakshmi Reshma
1
;
Rahul Vats
;
Renuka Janupally
;
Shalini Saxena
;
Perumal Yogeeswari
;
Dharmarajan Sriram
;
dsriram@hyderabad.bits-pilani.ac.in" class="auth_mail" title="E-mail the corresponding author
关键词:
Medium throughput virtual screening
;
Mycobacterium tuberculosis
;
DNA gyrase
;
Differential
scanning
fluorimetry
刊名:European Journal of Medicinal Chemistry
出版年:2016
10.
The unusual substrate specificity of a virulence associated serine hydrolase from the highly toxic bacterium, Francisella tularensis
作者:
Alexander M. Farberg
;
Whitney K. Hart
;
R. Jeremy Johnson
;
rjjohns1@butler.edu" class="auth_mail" title="E-mail the corresponding author
关键词:
DSF
;
differential
scanning
fluorimetry
;
FTT0941c
;
virulence associated serine hydrolase from Francisella tularensis
;
HSL
;
hormone sensitive lipase
;
KEGG
;
Kyoto Encyclopedia of Genes and Genomes
;
LB
;
Luria-Bertani broth
;
MWCO
;
molecular weight cut-off
;
Ni-NTA
;
nickel-nitrilotriacetic acid
;
PDB
;
protein data bank
刊名:Biochemistry and Biophysics Reports
出版年:2016
1
2
3
4
5
6
7
按检索点细分(65)
题名(9)
关键词(40)
文摘(37)
按出版年细分(65)
2027年及以后(5)
2017年(3)
2016年(9)
2015年(5)
2013年(10)
2012年(9)
2011年(6)
2010年(4)
2009年(4)
2008年(1)
2004年(2)
2003年(1)
2002年(1)
2000年及以前(5)
NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via
email
.