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NATURE电子期刊(58)
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在“
Elsevier电子期刊
”中,
命中:
3,516
条,耗时:0.1039448 秒
在所有数据库中总计命中:
6,079
条
1.
Location of contact residues in pharmacologically distinct drug
binding
site
s on P-glycoprotein
作者:
Rituparna Mittra
a
;
Megan Pavy
a
;
Nanditha Subramanian
b
;
Anthony M. George
c
;
Megan L. O'Mara
b
;
Ian D. Kerr
d
;
Richard Callaghan
a
;
richard.callaghan@anu.edu.au
关键词:
Vinblastine sulphate (PubMed CID
;
5388983)
;
Nicardipine hydrochloride (PubMed CID
;
41114)
;
Paclitaxel (PubMed CID
;
36314)
;
Rhodamine123 (PubMed CID
;
9929799)
;
Adenosine triphosphate (PubMed CID
;
5957)
刊名:Biochemical Pharmacology
出版年:2017
2.
Characterization of P2X4 receptor agonists and antagonists by calcium influx and radioligand
binding
studies
作者:
Aliaa Abdelrahman
a
;
Vigneshwaran Namasivayam
a
;
c
;
Sonja Hinz
a
;
Anke C. Schiedel
a
;
Meryem Kö
;
se
a
;
Maggi Burton
b
;
Ali El-Tayeb
a
;
1
;
Michel Gillard
b
;
Jü
;
rgen Bajorath
c
;
Marc de Ryck
b
;
Christa E. Mü
;
ller
a
;
christa.mueller@uni-bonn.de
关键词:
Ap3A
;
diadenosine triphosphate
;
Ap4A
;
diadenosine tetraphosphate
;
Ap5A
;
diadenosine pentaphosphate
;
AR-C67085MX
;
2-propylthio-β
;
γ-dichloromethylene-ATP
;
PSB0412
;
2-propargylthio-β
;
γ-dichloromethylene-ATP
;
5-BDBD
;
5-(3-bromophenyl)-1
;
3-dihydro-2H-benzofuro[3
;
2-e]-1
;
4-diazepin-2-one
;
BzATP
;
2&prime
;
(3&prime
;
)-O-(4-benzoylbenzoyl)adenosine 5&prime
;
-triphosphate
;
CHO-K1 cells
;
Chinese hamster ovary cells
;
HBSS
;
Hank&rsquo
;
s balanced salt solution
;
HEPES
;
4-(2-hydroxyethyl)-1-piperazine ethanesulfoni
刊名:Biochemical Pharmacology
出版年:2017
3.
Severe fluoropyrimidine toxicity due to novel and rare DPYD missense mutations, deletion and genomic amplification affecting DPD activity and mRNA splicing
作者:
André
;
B.P. van Kuilenburg
a
;
a.b.vankuilenburg@amc.uva.nl
;
Judith Meijer
a
;
Dirk Maurer
b
;
Doreen Dobritzsch
b
;
Rutger Meinsma
a
;
Maartje Los
c
;
Lia C. Knegt
a
;
Lida Zoetekouw
a
;
Rob L.H. Jansen
d
;
Vincent Dezentjé
;
e
;
Lieke H. van Huis-Tanja
f
;
Roel J.W. van Kampen
g
;
Jens Michael Hertz
h
;
Raoul C.M. Hennekam
a
关键词:
Dihydropyrimidine dehydrogenase
;
DPYD
;
5-Fluorouracil
;
Capecitabine
;
Pharmacogenetics
;
Toxicity
刊名:Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
出版年:2017
4.
In silico identification and computational analysis of the
nucleotide
binding
site
in the C-terminal domain of Hsp90
作者:
Samir S. Roy
;
Manju Kapoor
;
mkapoor37@yahoo.com
关键词:
Hsp90
;
C-terminal domain
;
Nucleotide
binding
site
;
Molecular docking
;
Homology modeling
刊名:Journal of Molecular Graphics and Modelling
出版年:2016
5.
Genetic Variants in CD44 and MAT1A Confer Susceptibility to Acute Skin Reaction in Breast Cancer Patients Undergoing Radiation Therapy
作者:
Kamalesh Dattaram Mumbrekar
;
PhD
&lowast
;
;
Satish Rao Bola Sadashiva
;
PhD
&lowast
;
;
Shama Prasada Kabekkodu
;
PhD
&dagger
;
;
Donald Jerard Fernandes
;
MD
&Dagger
;
;
Bejadi Manjunath Vadhiraja
;
MD
§
;
;
Tomo Suga
;
MS
‖
;
Yoshimi Shoji
;
BS
‖
;
Fumiaki Nakayama
;
MD
;
PhD
‖
;
Takashi Imai
;
PhD
‖
;
Kapaettu Satyamoorthy
;
PhD
&dagger
;
;
ksatyamoorthy@yahoo.com
刊名:International Journal of Radiation Oncology*Biology*Physics
出版年:2017
6.
Prediction and characterization of P-glycoprotein substrates potentially bound to different
site
s by emerging chemical pattern and hierarchical cluster analysis
作者:
Xianchao Pan
a
;
b
;
Hu Mei
a
;
b
;
meihu@cqu.edu.cn" class="auth_mail" title="E-mail the corresponding author
;
Sujun Qu
b
;
Shuheng Huang
b
;
Jiaying Sun
c
;
Li Yang
a
;
b
;
Hua Chen
d
;
chenhuacqu@aliyun.com" class="auth_mail" title="E-mail the corresponding author
关键词:
P-gp
;
P-glycoprotein
;
ABC
;
ATP-
binding
cassette
;
MDR
;
multidrug resistance
;
EP
;
emerging pattern
;
ECP
;
emerging chemical pattern
;
ECPG
;
emerging chemical pattern group
;
TM
;
transmembrane
;
TMD
;
transmembrane domain
;
NBD
;
nucleotide
-
binding
domain
;
SBS
;
substrate-
binding
site
;
QSAR
;
quantitative structure-activity relationship
;
CAEP
;
Classification by Aggregating Emerging Patterns
;
HCA
;
hierarchical cluster analysis
;
Acc
;
accuracy
;
Spe
;
specificity
;
TP
;
true positive
;
TN
;
true negative
;
FP
;
false
刊名:International Journal of Pharmaceutics
出版年:2016
7.
On the ATP
binding
site
of the ε subunit from bacterial F-type ATP synthases
作者:
Alexander Krah
;
krah@theory.biophys.kyoto-u.ac.jp" class="auth_mail" title="E-mail the corresponding author
;
Shoji Takada
关键词:
ATP
binding
site
;
ATPase inhibition
;
ε subunit
;
F-type ATPase
;
thermophilic Bacillus PS3
刊名:Biochimica et Biophysica Acta (BBA) - Bioenergetics
出版年:2016
8.
Functional Mutations Form at CTCF-Cohesin
Binding
Site
s in Melanoma Due to Uneven
Nucleotide
Excision Repair across the Motif
作者:
Rebecca C. Poulos
1
;
Julie A.I. Thoms
1
;
Yi Fang Guan
1
;
Ashwin Unnikrishnan
1
;
John E. Pimanda
1
;
2
;
Jason W.H. Wong
1
;
3
;
4
;
jason.wong@unsw.edu.au
关键词:
melanoma
;
CTCF
;
somatic mutation
;
topologically associating domain
;
nucleotide
excision repair
;
cohesin
;
allele-specific ChIP-seq
;
COLO-829
刊名:Cell Reports
出版年:2016
9.
Nucleotide
dependence of the dimerization of ATP
binding
cassette
nucleotide
binding
domains
作者:
Gregory A. Fendley
a
;
Ina L. Urbatsch
b
;
c
;
Roger B. Sutton
a
;
b
;
Maria E. Zoghbi
d
;
Guillermo A. Altenberg
a
;
b
;
g.altenberg@ttuhsc.edu" class="auth_mail" title="E-mail the corresponding author
关键词:
ABC protein
;
Tryptophan fluorescence
;
Dimer
;
Motor domain
;
ATPase
刊名:Biochemical and Biophysical Research Communications
出版年:2016
10.
The C421A (Q141K) polymorphism enhances the 3‿untranslated region (3‿UTR)-dependent regulation of ATP-
binding
cassette transporter ABCG2
作者:
Anne Ripperger
;
Ralf A. Benndorf
;
ralf.benndorf@pharmazie.uni-halle.de" class="auth_mail" title="E-mail the corresponding author
关键词:
ATP-
binding
cassette (ABC) transporter
;
ABCG2/BCRP
;
Single
nucleotide
polymorphism
;
C421A (Q141K) variant
;
microRNA
;
hsa-miR-328
;
hsa-miR-519c
;
hsa-miR-520h
刊名:Biochemical Pharmacology
出版年:2016
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