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在“
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”中,
命中:
3,602
条,耗时:0.015985 秒
在所有数据库中总计命中:
4,473
条
1.
Discovery, structure-activity relationship studies, and anti-nociceptive effects of N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)benzamides as novel
opioid
receptor
agonist
s
作者:
Sheng-Ren Chen
a
;
c
;
Yi-Yu Ke
a
;
1
;
Teng-Kuang Yeh
a
;
1
;
Shu-Yu Lin
a
;
Li-Chin Ou
a
;
Shu-Chun Chen
a
;
Wan-Ting Chang
a
;
Hsiao-Fu Chang
a
;
Zih-Huei Wu
a
;
Chih-Chien Hsieh
a
;
Ping-Yee Law
b
;
Horace H. Loh
b
;
Chuan Shih
a
;
Yiu-Kay Lai
c
;
yklai@life.nthu.edu.tw
;
Shiu-Hwa Yeh
a
;
d
;
bau9763@bp.nhri.org.tw
;
Shau-Hua Ueng
a
;
shueng@nhri.org.tw
关键词:
μ-
opioid
receptor
agonist
;
κ-
opioid
receptor
agonist
;
Structure-activity relationship
;
Blood-brain barrier
;
Penetration
;
Anti-nociceptive effects
;
Tail-flick test
刊名:European Journal of Medicinal Chemistry
出版年:2017
2.
Effectiveness of adjunctive, personalised psychosocial intervention for non-response to
opioid
agonist
treatment: Study protocol for a pragmatic randomised controlled trial
作者:
John Marsden
a
;
b
;
john.marsden@kcl.ac.uk
;
Garry Stillwell
a
;
b
;
Jennifer Hellier
c
;
Anne Marie Brown
a
;
b
;
Sarah Byford
d
;
Michael Kelleher
b
;
Joanne Kelly
e
;
Caroline Murphy
e
;
James Shearer
d
;
Luke Mitcheson
b
关键词:
Heroin
;
Cocaine
;
Opioid
substitution
;
Psychosocial
;
Trial
刊名:Contemporary Clinical Trials
出版年:2017
3.
Pharmacological studies on the NOP and
opioid
receptor
agonist
PWT2-[Dmt
1
]N/OFQ(1-13)
作者:
Maria Camilla Cerlesi
a
;
Huiping Ding
b
;
Mark F. Bird
c
;
Norikazu Kiguchi
b
;
Federica Ferrari
a
;
Davide Malfacini
a
;
Anna Rizzi
a
;
Chiara Ruzza
a
;
David G. Lambert
c
;
Mei-Chuan Ko
b
;
Girolamo Calo
a
;
;
Remo Guerrini
d
关键词:
PWT2-[Dmt1]N/OFQ(1&ndash
;
13)
;
NOP and
opioid
receptors
;
Receptor binding
;
Stimulation of [35S]GTPγS binding
;
Calcium mobilization
;
Monkey spinal analgesia
刊名:European Journal of Pharmacology
出版年:2017
4.
Suppression of the acute upregulation of phosphorylated-extracellular regulated kinase in ventral tegmental area by a μ-
opioid
receptor
agonist
is related to resistance to rewarding effects in a mouse model of bone cancer
作者:
Atsushi Nakamura
;
atsushi_nakamura@shionogi.co.jp
;
Hiroko Ono
;
Azusa Ando
;
Mikie Hinata
;
Kazuki Niidome
;
Shigeki Omachi
;
Gaku Sakaguchi
;
Shunji Shinohara
关键词:
Antinociception
;
Bone cancer pain
;
Extracellular regulated kinase
;
Opioid
;
Rewarding effect
刊名:Journal of Pharmacological Sciences
出版年:2017
5.
Benzylideneoxymorphone: A new lead for development of bifunctional mu/delta
opioid
receptor ligands
作者:
Jason R. Healy
a
;
b
;
Padmavani Bezawada
c
;
Nicholas W. Griggs
d
;
Andrea L. Devereaux
e
;
Rae R. Matsumoto
a
;
f
;
John R. Traynor
d
;
Andrew Coop
c
;
Christopher W. Cunningham
e
;
chris.cunningham@cuw.edu
关键词:
Mu
opioid
receptor
;
Delta
opioid
receptor
;
Analgesic tolerance
;
Oxymorphone
;
Benzylideneoxymorphone
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2017
6.
Modulation of serotonin transporter function by kappa-
opioid
receptor ligands
作者:
Santhanalakshmi Sundaramurthy
a
;
Balasubramaniam Annamalai
b
;
Devadoss J. Samuvel
c
;
Toni S. Shippenberg
d
;
Lankupalle D. Jayanthi
a
;
Sammanda Ramamoorthy
a
;
sammanda.ramamoorthy@vcuhealth.org
关键词:
Kappa
opioid
receptor
;
Serotonin
;
Clearance
;
Serotonin transporter
;
Phosphorylation
;
Trafficking
刊名:Neuropharmacology
出版年:2017
7.
(+)-and (−)-Phenazocine enantiomers: Evaluation of their dual
opioid
agonist
/σ
1
ant
agonist
properties and antinociceptive effects
关键词:
Sigma-1 receptor
;
(+)-Phenazocine
;
(&minus
;
)-Phenazocine
;
Mechanical antinociception
;
Bifunctional ligand
;
Opioid
刊名:European Journal of Medicinal Chemistry
出版年:2017
8.
Thalidomide attenuates the development and expression of antinociceptive tolerance to μ-
opioid
agonist
morphine through l-arginine-iNOS and nitric oxide pathway
作者:
Muhammad Imran Khan
a
;
b
;
c
;
Sattar Ostadhadi
a
;
c
;
Faiza Mumtaz
a
;
b
;
Majid Momeny
a
;
b
;
d
;
Farima Moghaddaskho
a
;
b
;
Mahsa Hassanipour
b
;
Shahram Ejtemaei-Mehr
a
;
b
;
Ahmad Reza Dehpour
a
;
b
;
c
;
dehpour@yahoo.com
关键词:
Thalidomide
;
Morphine
;
Antinociception
;
Tolerance
;
Nitric oxide
;
Mice
刊名:Biomedicine & Pharmacotherapy
出版年:2017
9.
Relapse to
opioid
use in
opioid
-dependent individuals released from compulsory drug detention centres compared with those from voluntary methadone treatment centres in Malaysia: a two-arm, prospective observational study
作者:
Martin P Wegman
;
BSc
a
;
b
;
c
;
Prof Frederick L Altice
;
MD
a
;
b
;
frederick.altice@yale.edu
;
Sangeeth Kaur
;
MBBS
d
;
Vanesa Rajandaran
;
MPP
b
;
Sutayut Osornprasop
;
PhD
e
;
David Wilson
;
PhD
e
;
Prof David P Wilson
;
PhD
f
;
Adeeba Kamarulzaman
;
FRACP
a
;
b
刊名:The Lancet Global Health
出版年:2017
10.
A systematic review of
opioid
agonist
treatments for pharmaceutical
opioid
dependence
作者:
Suzanne Nielsen
3
;
2
;
;
Briony Larance
3
;
Louisa Degenhardt
3
;
Linda Gowing
1
;
Nicholas Lintzeris
2
;
4
刊名:Drug and Alcohol Dependence
出版年:2017
1
2
3
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5
6
7
8
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