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内部出版物
Wiley电子期刊(9)
NATURE电子期刊(1)
ACS电子期刊(48)
SpringerLink电子期刊(353)
Elsevier电子期刊(935)
在“
Elsevier电子期刊
”中,
命中:
935
条,耗时:小于0.01 秒
在所有数据库中总计命中:
1,346
条
1.
Design, synthesis and analgesic/anti-inflammatory evaluation of novel diarylthiazole and diarylimidazole derivatives towards
selective
COX
-1
inhibitors
with better gastric profile
作者:
Ahmed H. Abdelazeem
a
;
b
;
ahmed.abdelazeem@pharm.bsu.edu.eg
;
ahmed.pharm@yahoo.com
;
Mohammed T. El-Saadi
a
;
Asmaa G. Safi El-Din
a
;
Hany A. Omar
c
;
d
;
Samir M. El-Moghazy
e
;
samirelmoghazy@gmail.com
关键词:
Selective
COX
-1
;
Mofezolac
;
Diarylthiazole
;
Diarylimidazole
;
Analgesic
;
Anti-inflammatory
;
Ulcerogenicity
刊名:Bioorganic & Medicinal Chemistry
出版年:
2
017
2.
In silico receptor-based drug design of X,Y-benzenesulfonamide derivatives as
selective
COX
-
2
inhibitors
作者:
David J. Pé
;
rez
a
;
Orlando Sarabia
a
;
Manuel Villanueva-Garcí
;
a
b
;
Kayim Pineda-Urbina
a
;
Á
;
ngel Ramos-Organillo
a
;
Jorge Gonzalez-Gonzalez
a
;
Zeferino Gó
;
mez-Sandoval
a
;
zgomez@ucol.com
;
Rodrigo Said Razo-Herná
;
ndez
a
;
c
;
rrazo@ucol.mx
关键词:
QSAR
;
Docking
;
Cyclooxygenase
;
Benzenesulfonamides
;
Drug design
;
Artificial neural networks
刊名:Comptes Rendus Chimie
出版年:
2
017
3.
Selective
Serotonin Reuptake
Inhibitors
and Poststroke Epilepsy: A Population-Based Nationwide Study
作者:
Chien-Chen Chou
;
MD
a
;
b
;
Der-Jen Yen
;
MD
a
;
b
;
Yung-Yang Lin
;
MD
;
PhD
a
;
c
;
d
;
Yu-Chiao Wang
;
MSc
e
;
g
;
Cheng-Li Lin
;
MSc
e
;
g
;
Chia-Hung Kao
;
MD
f
;
h
;
i
;
d10040@mail.cmuh.org.tw
关键词:
aHR
;
adjusted hazard ratio
;
DDD
;
defined daily dose
;
HR
;
hazard ratio
;
ICD-9-CM
;
International Classification of Diseases
;
Ninth Revision
;
Clinical Modification
;
IQR
;
interquartile range
;
LHID
2
000
;
Longitudinal Health Insurance Database
2
000
;
NHI
;
National Health Insurance
;
NHIRD
;
National Health Insurance Research Database
;
PY
;
person-year
;
SSRI
;
selective
serotonin reuptake inhibitor
刊名:Mayo Clinic Proceedings
出版年:
2
017
4.
Bifunctional conjugates with potent inhibitory activity towards cyclooxygenase and histone deacetylase
作者:
Idris Raji
a
;
Fatima Yadudu
a
;
Emily Janeira
e
;
Shaghayegh Fathi
a
;
Lindsey Szymczak
c
;
James Richard Kornacki
c
;
Kensei Komatsu
d
;
Jian-Dong Li
d
;
Milan Mrksich
c
;
Adegboyega K. Oyelere
a
;
b
;
aoyelere@gatech.edu
关键词:
HDAC
;
histone deacetylase
;
HDACi
;
histone deacetylase
inhibitors
;
COX
;
cyclooxygenases
;
NSAIDs
;
non-steroidal anti-inflammatory drugs
;
AR
;
androgen receptor
;
ZBG
;
zinc binding group
;
PGE
2
;
prostaglandin E
2
刊名:Bioorganic & Medicinal Chemistry
出版年:
2
017
5.
Mitochondrial toxicity of
selective
COX
-
2
inhibitors
via inhibition of oxidative phosphorylation (ATP synthesis) in rat liver mitochondria
作者:
Muzeeb Syed
a
;
muzeeb.syed@sund.ku.dk" class="auth_mail" title="E-mail the corresponding author
;
Christian Skonberg
b
;
Steen Honoré
;
Hansen
a
关键词:
Drug induced liver injury
;
Selective
COX
-
2
inhibitors
;
Rat liver mitochondria
;
Oxidative phosphorylation
;
ATP
;
In vitro metabolism
刊名:Toxicology in Vitro
出版年:
2
016
6.
Synthesis and biological evaluation of fluorinated 1,5-diarylpyrrole-3-alkoxyethyl ether derivatives as
selective
COX
-
2
inhibitors
endowed with anti-inflammatory activity
作者:
Angela Di Capua
a
;
1
;
Claudia Sticozzi
b
;
Simone Brogi
a
;
Margherita Brindisi
a
;
Andrea Cappelli
a
;
Lidia Sautebin
c
;
Antonietta Rossi
c
;
Simona Pace
c
;
Carla Ghelardini
d
;
Lorenzo Di Cesare Mannelli
d
;
Giuseppe Valacchi
b
;
e
;
Gianluca Giorgi
a
;
Antonio Giordani
f
;
Giovanna Poce
g
;
Mariangela Biava
g
;
Maurizio Anzini
a
;
maurizio.anzini@unisi.it" class="auth_mail" title="E-mail the corresponding author
关键词:
COX
-
2
inhibitors
;
1
;
5-diarylpyrrole derivatives
;
Anti-inflammatory agents
;
Antinociceptive agents
;
Antiproliferative activity
;
Molecular modelling
刊名:European Journal of Medicinal Chemistry
出版年:
2
016
7.
In vitro pharmacological evaluation of multitarget agents for thromboxane prostanoid receptor antagonism and
COX
-
2
inhibition
作者:
Malvina Hoxha
a
;
1
;
Carola Buccellati
a
;
1
;
Valé
;
rie Capra
c
;
Davide Garella
b
;
Clara Cena
b
;
Barbara Rolando
b
;
Roberta Fruttero
b
;
Silvia Carnevali
a
;
Angelo Sala
a
;
G.Enrico Rovati
a
;
genrico.rovati@unimi.it" class="auth_mail" title="E-mail the corresponding author
;
Massimo Bertinaria
b
关键词:
AA
;
arachidonic acid
;
CV
;
cardiovascular
;
COX
;
cyclooxygenase
cox
ibs
;
COX
-
2
;
selective
inhibitors
;
DMEM
;
Dulbecco&rsquo
;
s modified eagle&rsquo
;
s medium
;
EIA
;
enzyme immunoassay
;
IP
;
inositol phosphate
;
HEK
2
93
;
human embryonic kidney
2
93
;
NSAID
;
nonsteroidal anti-inflammatory drug
;
PG
;
prostaglandin
;
TXA
2
;
thromboxane A
2
;
TP
;
thromboxane prostanoid receptor
刊名:Pharmacological Research
出版年:
2
016
8.
Synthesis, cyclooxygenase inhibition, anti-inflammatory evaluation and ulcerogenic liability of new 1,3,5-triarylpyrazoline and 1,5-diarylpyrazole derivatives as
selective
COX
-
2
inhibitors
作者:
Khaled R.A. Abdellatif
a
;
khaled.ahmed@pharm.bsu.edu.eg" class="auth_mail" title="E-mail the corresponding author
;
Eman K.A. Abdelall
a
;
Wael A.A. Fadaly
a
;
Gehan M. Kamel
b
关键词:
Anti-inflammatory
;
Pyrazoline
;
1
;
5-Diarylpyrazole
;
Cyclooxygenase-
2
inhibitors
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:
2
016
9.
Coumarin sulfonamides derivatives as potent and
selective
COX
-
2
inhibitors
with efficacy in suppressing cancer proliferation and metastasis
作者:
Xiao-Yuan Lu
&dagger
;
;
Zhong-Chang Wang
;
&dagger
;
;
Shen-Zhen Ren
;
Fa-Qian Shen
;
Ruo-Jun Man
;
Hai-Liang Zhu
;
zhuhl@nju.edu.cn" class="auth_mail" title="E-mail the corresponding author
关键词:
Coumarin
;
Sulfonamides
;
COX
-
2
inhibitor
;
Anticancer
;
Docking simulation
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:
2
016
10.
Computer-aided drug design guided by hydrogen/deuterium exchange mass spectrometry: A powerful combination for the development of potent and
selective
inhibitors
of Group VIA calcium-independent phospholipase A
2
作者:
Varnavas D. Mouchlis
a
;
vmouchlis@gmail.com" class="auth_mail" title="E-mail the corresponding author
;
Christophe Morisseau
b
;
Bruce D. Hammock
b
;
Sheng Li
c
;
J. Andrew McCammon
a
;
jmccammon@ucsd.edu" class="auth_mail" title="E-mail the corresponding author
;
Edward A. Dennis
a
;
edennis@ucsd.edu" class="auth_mail" title="E-mail the corresponding author
关键词:
Phospholipase A
2
;
Trifluoromethylketones
;
Thioether
;
DXMS
;
Docking
;
MD simulations
;
Structure&ndash
;
activity relationship
刊名:Bioorganic & Medicinal Chemistry
出版年:
2
016
1
2
3
4
5
6
7
8
9
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