设为首页
收藏本站
网站地图
|
English
|
公务邮箱
About the library
Background
History
Leadership
Organization
Readers' Guide
Opening Hours
Collections
Help Via Email
Publications
Electronic Information Resources
常用资源
电子图书
期刊论文
学位会议
外文资源
特色专题
内部出版物
Wiley电子期刊(17)
NATURE电子期刊(13)
ACS电子期刊(256)
SpringerLink电子期刊(174)
Elsevier电子期刊(603)
在“
Elsevier电子期刊
”中,
命中:
603
条,耗时:0.0869592 秒
在所有数据库中总计命中:
1,063
条
1.
Binding
of small molecules at interface of protein-protein complex - A newer approach to rational drug design
作者:
A.B. Gurung
a
;
A. Bhattacharjee
a
;
M. Ajmal Ali
b
;
alimohammad@ksu.edu.sa
;
F. Al-Hemaid
b
;
Joongku Lee
c
关键词:
Hot spots
;
Protein interfaces
;
Druggability
;
Orthosteric inhibitor
;
Allosteric inhibitor
;
Interfacial
binding
inhibitor
刊名:Saudi Journal of Biological Sciences
出版年:2017
2.
Lessons from Enzyme
Kinetics
Reveal Specificity Principles for RNA-Guided Nucleases in RNA Interference and CRISPR-Based Genome Editing
作者:
Namita Bisaria
1
;
5
;
6
;
Inga Jarmoskaite
1
;
6
;
Daniel Herschlag
1
;
2
;
3
;
4
;
7
;
herschla@stanford.edu
刊名:Cell Systems
出版年:2017
3.
Structure activity relationships of benzylproline-derived inhibitors of the glutamine transporter ASCT2
作者:
Kurnvir Singh
a
;
Rose Tanui
a
;
Armanda Gameiro
a
;
1
;
Gilad Eisenberg
a
;
Claire Colas
b
;
Avner Schlessinger
b
;
Christof Grewer
a
;
cgrewer@binghamton.edu
关键词:
Neutral amino acid transporter
;
ASCT2
;
Inhibitors
;
Glutamine transport
;
Kinetics
;
Patch clamp
;
Pharmacology
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2017
4.
Enhanced potency of bivalent small molecule gp41 inhibitors
作者:
Vladimir Sofiyev
a
;
Hardeep Kaur
a
;
Beth A. Snyder
c
;
Priscilla A. Hogan
c
;
Roger G. Ptak
c
;
Peter Hwang
d
;
Miriam Gochin
a
;
b
;
miriam.gochin@tu.edu
关键词:
HIV-1 gp41
;
Hydrophobic pocket
;
Fusion inhibition
;
Peptidomimetic inhibitors
;
Bivalent inhibitors
;
Fluorescence
;
Surface plasmon resonance
;
Kinetics
;
Cooperativity
刊名:Bioorganic & Medicinal Chemistry
出版年:2017
5.
Imaging Transcriptional Regulation of Eukaryotic mRNA Genes: Advances and Outlook
作者:
Jie Yao
yao.j@yale.edu
关键词:
Pol II
;
RNA polymerase II
;
TF
;
transcription factor
;
TBP
;
TATA-
binding
protein
;
TAF
;
TBP-associated factor
;
GTF
;
general transcription factor
;
PIC
;
transcription preinitiation complex
;
CTD
;
C-terminal domain
;
ncRNA
;
non-coding RNA
;
eRNA
;
enhancer RNA
;
FRAP
;
fluorescence recovery after photobleaching
;
GFP
;
green fluorescence protein
;
MMTV
;
mouse mammary tumor virus
;
FISH
;
fluorescence in situ hybridization
;
TS
;
transcription site
;
ES
;
embryonic stem
;
SRF
;
serum response factor
;
ER
;
estrogen recep
刊名:Journal of Molecular Biology
出版年:2017
6.
Structural insight into a novel neutral metalloproteinase from Paenibacillus spp. BD3526: Implications for mechanisms of rapid inactivation and calcium-dependent stability
作者:
Feng Hang
a
;
b
;
Qinbo Wang
a
;
Qing Hong
a
;
Caixia Gao
a
;
Hao Zhang
b
;
Wei Chen
b
;
c
;
chenwei66@jiangnan.edu.cn
关键词:
Paenibacillus
;
Metalloproteinase
;
Autoproteolysis
;
Calcium
刊名:International Journal of Biological Macromolecules
出版年:2017
7.
Tanshinone IIA induced cell death via miR30b-p53-PTPN11/SHP2 signaling pathway in human hepatocellular carcinoma cells
作者:
Xuanqi Ren
a
;
1
;
Cui Wang
a
;
1
;
Binbin Xie
a
;
Linfeng Hu
a
;
Hui Chai
a
;
Lei Ding
a
;
Lihua Tang
a
;
Yongliang Xia
b
;
xiayongliang1@sina.com
;
Xiaobing Dou
a
;
xbdou77@163.com
关键词:
Tanshinone IIA
;
miR30b-p53
;
PTPN11
;
HepG2 cells
;
Cell death
刊名:European Journal of Pharmacology
出版年:2017
8.
Perspectives on variability in pharmaco
kinetics
of an oral contraceptive product
作者:
William J. Jusko
;
wjjusko@buffalo.edu
关键词:
Pharmaco
kinetics
;
Oral contraceptives
;
Ethinyl estradiol
;
Levonorgestrel
刊名:Contraception
出版年:2017
9.
Effects of
Kinetics
and State-Dependent
Binding
Properties of I
Kur
Target
ing Drugs on Atrial Electrophysiology
刊名:Biophysical Journal
出版年:2017
10.
Identification of a selective inhibitor of transforming growth factor β-activated kinase 1 by biosensor-based screening of focused libraries
作者:
Takaaki Miura
a
;
miuratka@chugai-pharm.co.jp
;
Atsushi Matsuo
b
;
Terushige Muraoka
b
;
Mitsuaki Ide
b
;
Kenji Morikami
b
;
Takayuki Kamikawa
a
;
Masamichi Nishihara
b
;
Hirotaka Kashiwagi
b
关键词:
TAK1
;
Chemogenomic approach
;
Selective Type I inhibitor
;
Biophysical screening
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:2017
1
2
3
4
5
6
7
8
9
按检索点细分(603)
题名(5)
关键词(4)
文摘(485)
按出版年细分(603)
2027年及以后(23)
2017年(11)
2016年(35)
2015年(7)
2013年(39)
2012年(47)
2011年(49)
2010年(40)
2009年(42)
2008年(38)
2007年(28)
2006年(27)
2005年(28)
2004年(25)
2003年(15)
2002年(17)
2001年(24)
2000年(17)
2000年及以前(91)
NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via
email
.