设为首页
收藏本站
网站地图
|
English
|
公务邮箱
About the library
Background
History
Leadership
Organization
Readers' Guide
Opening Hours
Collections
Help Via Email
Publications
Electronic Information Resources
常用资源
电子图书
期刊论文
学位会议
外文资源
特色专题
内部出版物
Wiley电子期刊(23)
SpringerLink电子期刊(1237)
Elsevier电子期刊(3367)
Springer电子图书(25)
NATURE电子期刊(30)
ACS电子期刊(311)
在“
Elsevier电子期刊
”中,
命中:
3,367
条,耗时:小于0.01 秒
在所有数据库中总计命中:
4,993
条
1.
Novel trifluoromethylated 9-amino-3,4-dihydroacridin-
1
(2H)-ones act as covalent poisons of human
topoisomerase
IIα
作者:
Lorena Infante Lara
a
;
Alexis Sledge
d
;
Amine Laradji
d
;
Cosmas O. Okoro
d
;
cokoro@tnstate.edu
;
Neil Osheroff
a
;
b
;
c
;
neil.osheroff@vanderbilt.edu
关键词:
Acridin-
1
(2H)-ones
;
DNA
topoisomerase
IIα
;
Anticancer drugs
;
Covalent poison
;
DNA cleavage
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:20
1
7
2.
Synthesis and biological evaluation of naphthoquinone-coumarin conjugates as
topoisomerase
II inhibitors
作者:
Idaira Hueso-Falcó
;
n
a
;
Á
;
ngel Amesty
a
;
1
;
Laura Anaissi-Afonso
b
;
1
;
Isabel Lorenzo-Castrillejo
b
;
Fé
;
lix Machí
;
n
b
;
fmachin@funcanis.org
;
Ana Esté
;
vez-Braun
a
;
aestebra@ull.es
关键词:
2-Hydroxynaphthoquinone
;
4-Hydroxycoumarin
;
Privileged structures
;
Topoisomerase
II
;
ATPase
;
Docking
刊名:Bioorganic & Medicinal Chemistry Letters
出版年:20
1
7
3.
Multifaceted properties of
1
,4-dimethylcarbazoles: Focus on trimethoxybenzamide and trimethoxyphenylurea derivatives as novel human
topoisomerase
II inhibitors
作者:
Domenico Iacopetta
a
;
Camillo Rosano
b
;
Francesco Puoci
a
;
Ortensia Ilaria Parisi
a
;
Carmela Saturnino
c
;
Anna Caruso
a
;
Pasquale Longo
d
;
Jessica Ceramella
a
;
Auré
;
lie Malzert-Fré
;
on
e
;
aurelie.malzert-freon@unicaen.fr
;
Patrick Dallemagne
e
;
Sylvain Rault
e
;
Maria Stefania Sinicropi
a
;
s.sinicropi@unical.it
关键词:
Human
topoisomerase
s I/II
;
Antitumor
;
Docking simulation
;
Thermal stability
;
Large unilamellar vesicles
刊名:European Journal of Pharmaceutical Sciences
出版年:20
1
7
4.
Synthesis, evaluation, and CoMFA study of fluoroquinophenoxazine derivatives as bacterial
topoisomerase
IA inhibitors
作者:
Xufen Yu
a
;
1
;
Mingming Zhang
a
;
1
;
Thirunavukkarasu Annamalai
b
;
Priyanka Bansod
b
;
Gagandeep Narula
b
;
Yuk-Ching Tse-Dinh
b
;
c
;
Dianqing Sun
a
;
dianqing@hawaii.edu
关键词:
Antibacterial
;
CoMFA analysis
;
3D-QSAR
;
Fluoroquinophenoxazine
;
Topoisomerase
IA
;
SAR
刊名:European Journal of Medicinal Chemistry
出版年:20
1
7
5.
Synthesis of pharmacologically important naphthoquinones and anticancer activity of 2-benzyllawsone through DNA
topoisomerase
-II inhibition
作者:
Balagani Sathish Kumar
a
;
Kusumoori Ravi
a
;
Amit Kumar Verma
a
;
Kaneez Fatima
a
;
Mohammad Hasanain
b
;
Arjun Singh
a
;
Jayanta Sarkar
b
;
Suaib Luqman
a
;
Debabrata Chanda
a
;
Arvind S. Negi
a
;
arvindcimap@rediffmail.com
关键词:
Naphthoquinones
;
Synthesis
;
Regioselective
;
Anticancer
;
Topoisomerase
;
Acute oral toxicity
刊名:Bioorganic & Medicinal Chemistry
出版年:20
1
7
6.
Fluorescein hydrazones: A series of novel non-intercalative
topoisomerase
IIα catalytic inhibitors induce G
1
arrest and apoptosis in breast and colon cancer cells
作者:
Mohammad Shahidul Islam
a
;
1
;
Seojeong Park
b
;
1
;
Chanju Song
b
;
Adnan A. Kadi
c
;
Youngjoo Kwon
b
;
ykwon@ewha.ac.kr
;
A.F.M. Motiur Rahman
c
;
afmrahman@ksu.edu.sa
关键词:
Fluorescein
;
Fluorescein hydrazones
;
Topoisomerase
IIα catalytic inhibitor
;
Apoptosis
刊名:European Journal of Medicinal Chemistry
出版年:20
1
7
7.
Novel indolizino[8,7-b]indole hybrids as anti-small cell lung cancer agents: Regioselective modulation of
topoisomerase
II inhibitory and DNA crosslinking activities
作者:
Sue-Ming Chang
a
;
Wilson Christian
a
;
b
;
Ming-Hsi Wu
a
;
Tai-Lin Chen
a
;
c
;
Yi-Wen Lin
a
;
Ching-Shu Suen
a
;
Hima Bindu Pidugu
a
;
Dilip Detroja
a
;
b
;
Anamik Shah
b
;
Ming-Jing Hwang
a
;
Tsann-Long Su
a
;
tlsu@ibms.sinica.edu.tw
;
Te-Chang Lee
a
;
bmtcl@ibms.sinica.edu.tw
关键词:
Anti-SCLC hybrids
;
β-carboline
;
bis(hydroxymethyl)pyrrole
;
indolizino[8
;
7-b]indole
;
DNA cross-linking
;
Topoisomerase
inhibition
刊名:European Journal of Medicinal Chemistry
出版年:20
1
7
8.
Novel 4-(4-substituted amidobenzyl)furan-2(5H)-one derivatives as
topoisomerase
I inhibitors
作者:
Cheng-Kang Peng
1
;
Ting Zeng
1
;
Xing-Jun Xu
;
Yi-Qun Chang
;
Wen Hou
;
Kuo Lu
;
Hui Lin
;
Ping-Hua Sun
;
Jing Lin
;
linjing_jnu@
1
63.com
;
Wei-Min Chen
;
twmchen@jnu.edu.cn
关键词:
Furan-2(5H)-one
;
α
;
β-unsaturated lactones
;
Topoisomerase
I
;
Antitumor
刊名:European Journal of Medicinal Chemistry
出版年:20
1
7
9.
Novel 2-aryl-4-(4′-hydroxyphenyl)-5H-indeno[
1
,2-b]pyridines as potent DNA non-intercalative
topoisomerase
catalytic inhibitors
作者:
Seojeong Park
a
;
1
;
Tara Man Kadayat
b
;
1
;
Kyu-Yeon Jun
a
;
Til Bahadur Thapa Magar
b
;
Ganesh Bist
b
;
Aarajana Shrestha
b
;
Eung-Seok Lee
b
;
eslee@yu.ac.kr
;
Youngjoo Kwon
a
;
ykwon@ewha.ac.kr
关键词:
Anticancer agents
;
2-Aryl-4-(4&prime
;
-hydroxyphenyl)-5H-indeno[
1
;
2-b]pyridine
;
Antiproliferative activity
;
Docking study
;
Dual
topoisomerase
I and II inhibitors
刊名:European Journal of Medicinal Chemistry
出版年:20
1
7
10.
Rational design, synthesis, and evaluation of novel 2,4-Chloro- and Hydroxy-Substituted diphenyl Benzofuro[3,2-b]Pyridines: Non-intercalative catalytic
topoisomerase
I and II dual inhibitor
作者:
Seojeong Park
a
;
1
;
Til Bahadur Thapa Magar
b
;
1
;
Tara Man Kadayat
b
;
Hwa Jong Lee
a
;
Ganesh Bist
b
;
Aarajana Shrestha
b
;
Eung-Seok Lee
b
;
eslee@ynu.ac.kr
;
Youngjoo Kwon
a
;
ykwon@ewha.ac.kr
关键词:2 ;
4-chloro- and hydroxy-substituted diphenyl benzofuro[3
;
2-b]pyridines
;
Dual
topoisomerase
I and II inhibition
;
Antiproliferative activity
;
Non-intercalative catalytic inhibiton
;
Anticancer agent
刊名:European Journal of Medicinal Chemistry
出版年:20
1
7
1
2
3
4
5
6
7
8
9
按检索点细分(3367)
题名(1412)
关键词(1410)
文摘(2804)
NGLC 2004-2010.National Geological Library of China All Rights Reserved.
Add:29 Xueyuan Rd,Haidian District,Beijing,PRC. Mail Add: 8324 mailbox 100083
For exchange or info please contact us via
email
.